This paper considers the problem of fault-tolerant control (FTC) and fault reconstruction of actuator faults for linear parametervarying (LPV) descriptor systems with time delay. A polytopic sliding mode observer (PSMO) is synthesized toachieve simultaneous reconstruction of LPV polytopic descriptor system states and actuator faults. Exploiting the reconstructedactuator faults and state estimates, a fault-tolerant controller is designed to compensate the impact of actuator faultson system performance by stabilizing the closed-loop LPV delayed descriptor system. Besides, the controller and PSMOgains are obtained throughout the resolution of linear matrix inequalities (LMIs) using convex optimization techniques. Thedeveloped PSMO could force the output estimation error to converge to zero in a finite time when the actuators faults arebounded through the reinjection of the output estimation error via a nonlinear switching term. Simulation results applied toa given numerical system are presented to highlight the superiority and effectiveness of the proposed approach.