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Orbicularisine: A Spiro-Indolothiazine Isolated from Gills of the Tropical Bivalve Codakia orbicularis

Abstract : A novel spiro-indolofuranone fused to a thiazine skeleton, orbicularisine (1), was isolated from gills of the mollusk Codakia orbicularis. The isolation and structure elucidation using spectroscopic evidence including mass and NMR spectroscopy are described. The final structure of 1 was supported by key HMBC correlation.
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Francesca Goudou, Philippe Petit, Céline Moriou, Olivier Gros, Ali Al-Mourabit. Orbicularisine: A Spiro-Indolothiazine Isolated from Gills of the Tropical Bivalve Codakia orbicularis. Journal of Natural Products, American Chemical Society, 2017, 80 (5), pp.1693-1696. ⟨10.1021/acs.jnatprod.7b00149⟩. ⟨hal-01547430⟩

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