Industrial Ecology (IE) is a multidisciplinary and complex field, which requires scientific and technical knowledge as well as the addressing of regional issues involving the economic and public regional actors. To train student on handling these IE aspects, the innovative pedagogical activity “TAMO LAVIVA” has been developed. The students play the role of public and private actors, who need to solve an environmental crisis regarding municipal waste management on the fictional island of TAMO LAVIVA. Thus, students are involved in a negotiation situation to reach a common solution, in the form of three waste management scenarios. This multi-faceted educational activity is based on the following educational objectives: - To understand the concepts and issues of industrial ecology (IE) in a given geopolitical context - To know how to apply IE tools: territorial metabolism, flow analysis, environmental and economic analysis - To acquire a general vision of flow management in an area and its links to regional dynamics (from the economic, social, environmental and governance perspectives) - To conduct a negotiation around an IE project After three years of experimentation, with 86 trained students, the feedback allows the obstacles and levers of this pedagogical activity to be highlighted. However, the 33h various activities (lectures, tutorials, visits, conferences, online course and the role-playing game) make it possible to juggle theoretical knowledge and its implementation through more playful teaching. Student’s feedback has been positive, particularly concerning negotiation, and this was illustrated by their involvement in reaching an agreement.