Evaluation of registration methods on thoracic CT: the EMPIRE10 challenge.
Keelin Murphy
(1)
,
Bram van Ginneken
(1)
,
Joseph M. Reinhardt
(2)
,
Sven Kabus
(3)
,
Kai Ding
(2)
,
Xiang Deng
(4)
,
Kunlin Cao
(2, 5)
,
Kaifang Du
(2)
,
Gary E. Christensen
(2)
,
Vincent Garcia
(6)
,
Tom Vercauteren
(7)
,
Nicholas Ayache
(8)
,
Olivier Commowick
(9)
,
Grégoire Malandain
(8)
,
Ben Glocker
(10)
,
Nikolaos Paragios
(11, 12)
,
Nassir Navab
(10)
,
Vladlena Gorbunova
(13)
,
Jon Sporring
(13)
,
Marleen de Bruijne
(13, 14)
,
Xiao Han
(15)
,
Mattias P. Heinrich
(16, 17)
,
Julia A. Schnabel
(16)
,
Mark Jenkinson
(17)
,
Cristian Lorenz
(3)
,
Marc Modat
(18)
,
Jamie R. Mcclelland
(18)
,
Sébastien Ourselin
(18)
,
Sacha Ea Muenzing
(1)
,
Max A. Viergever
(1)
,
Dante de Nigris
(19)
,
Louis D. Collins
(20, 21)
,
Tal Arbel
(19)
,
Marta Peroni
(22)
,
Rui Li
(22)
,
Gregory C. Sharp
(22)
,
Alexander Schmidt-Richberg
(23)
,
Jan Ehrhardt
(23)
,
René Werner
(23)
,
Dirk Smeets
(24)
,
Dirk Loeckx
(24)
,
Gang Song
(25)
,
Nicholas Tustison
(26)
,
Brian Avants
(25)
,
James C. Gee
(25)
,
Marius Staring
(27)
,
Stefan Klein
(14)
,
Berend C. Stoel
(27)
,
Martin Urschler
(28)
,
Manuel Werlberger
(28)
,
Jef Vandemeulebroucke
(29)
,
Simon Rit
(30)
,
David Sarrut
(30)
,
Josien Pw Pluim
(1)
1
ISI -
Image sciences institute - University of Utrecht
2 Department of Electrical and Computer Engineering [Iowa]
3 Philips Research [Germany]
4 Siemens [Beijing]
5 State Key Laboratory of Chemical Engineering (Polymerization Division)
6 Service DREAM
7 Mauna Kea Technologies
8 ASCLEPIOS - Analysis and Simulation of Biomedical Images
9 VisAGeS - Vision, Action et Gestion d'informations en Santé
10 CAMPAR - Computer Aided Medical Procedures & Augmented Reality
11 GALEN - Organ Modeling through Extraction, Representation and Understanding of Medical Image Content
12 MAS - Mathématiques Appliquées aux Systèmes - EA 4037
13 DIKU - Department of Computer Science [Copenhagen]
14 BIG - Biomedical Imaging Group [Rotterdam]
15 CMS Software
16 IBME - Institute of Biomedical Engineering [Oxford]
17 Department of Clinical Neurology [Oxford]
18 CMIC - Centre for Medical Image Computing
19 CIM - Centre for Intelligent Machines
20 Montreal Neurological Institute and Hospital
21 MNI - McConnell Brain Imaging Centre
22 Massachusetts General Hospital [Boston]
23 Institute of Medical Informatics [Lübeck]
24 Medical imaging research center [Leuven]
25 PICSL - Penn Image Computing & Science Lab [Philadelphia]
26 Department of radiology and medical imaging [Charlottesville]
27 Division of image processing [Leiden]
28 ICG - Institute for Computer Graphics and Vision [Graz]
29 CREATIS - Centre de Recherche en Acquisition et Traitement de l'Image pour la Santé
30 Imagerie Tomographique et Radiothérapie
2 Department of Electrical and Computer Engineering [Iowa]
3 Philips Research [Germany]
4 Siemens [Beijing]
5 State Key Laboratory of Chemical Engineering (Polymerization Division)
6 Service DREAM
7 Mauna Kea Technologies
8 ASCLEPIOS - Analysis and Simulation of Biomedical Images
9 VisAGeS - Vision, Action et Gestion d'informations en Santé
10 CAMPAR - Computer Aided Medical Procedures & Augmented Reality
11 GALEN - Organ Modeling through Extraction, Representation and Understanding of Medical Image Content
12 MAS - Mathématiques Appliquées aux Systèmes - EA 4037
13 DIKU - Department of Computer Science [Copenhagen]
14 BIG - Biomedical Imaging Group [Rotterdam]
15 CMS Software
16 IBME - Institute of Biomedical Engineering [Oxford]
17 Department of Clinical Neurology [Oxford]
18 CMIC - Centre for Medical Image Computing
19 CIM - Centre for Intelligent Machines
20 Montreal Neurological Institute and Hospital
21 MNI - McConnell Brain Imaging Centre
22 Massachusetts General Hospital [Boston]
23 Institute of Medical Informatics [Lübeck]
24 Medical imaging research center [Leuven]
25 PICSL - Penn Image Computing & Science Lab [Philadelphia]
26 Department of radiology and medical imaging [Charlottesville]
27 Division of image processing [Leiden]
28 ICG - Institute for Computer Graphics and Vision [Graz]
29 CREATIS - Centre de Recherche en Acquisition et Traitement de l'Image pour la Santé
30 Imagerie Tomographique et Radiothérapie
Bram van Ginneken
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Nicholas Ayache
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Olivier Commowick
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Grégoire Malandain
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Ben Glocker
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Marleen de Bruijne
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Marc Modat
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Stefan Klein
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Simon Rit
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David Sarrut
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Résumé
EMPIRE10 (Evaluation of Methods for Pulmonary Image REgistration 2010) is a public platform for fair and meaningful comparison of registration algorithms which are applied to a database of intrapatient thoracic CT image pairs. Evaluation of nonrigid registration techniques is a nontrivial task. This is compounded by the fact that researchers typically test only on their own data, which varies widely. For this reason, reliable assessment and comparison of different registration algorithms has been virtually impossible in the past. In this work we present the results of the launch phase of EMPIRE10, which comprised the comprehensive evaluation and comparison of 20 individual algorithms from leading academic and industrial research groups. All algorithms are applied to the same set of 30 thoracic CT pairs. Algorithm settings and parameters are chosen by researchers expert in the configuration of their own method and the evaluation is independent, using the same criteria for all participants. All results are published on the EMPIRE10 website (http://empire10.isi.uu.nl). The challenge remains ongoing and open to new participants. Full results from 24 algorithms have been published at the time of writing. This paper details the organization of the challenge, the data and evaluation methods and the outcome of the initial launch with 20 algorithms. The gain in knowledge and future work are discussed.
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