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Master Thesis

Étude in vitro de la durée d'écoulement de solutions antibiotiques préparées dans des diffuseurs portables élastomériques : effet du stockage au froid pendant trois à sept jours

Abstract : The management of patients with cystic fibrosis in Rhone-Alpes in France as elsewhere is organized around Centers of Expertise and Resources for Cystic Fibrosis (CRCM), but also a complementary manner with the participation of network EMERA (Together against Cystic fibrosis in Rhone-Alpes). The network offers EMERA including the organization of courses of intravenous antibiotics at home themselves prepared centrally in elastomeric infusion devices for use in the pharmacy inside the Grenoble University Hospital as one of the Hospices Civils de Lyon. However, it was found that the durations of infusion of these presenters were often higher than the nominal duration of infusion indicated by their manufacturers. The pharmacy of the University Hospital of Grenoble has therefore proposed to investigate the causes potential source of such non-compliance. The results of the in vitro study showed the impact: 1. Filling the time between the diffuser and flow of the solution, 2. Stockpiling of broadcasters cold, 3. of antibiotic concentration and hence the viscosity of the solution toadminister. It is therefore essential that health care teams are aware of factors which may lead to longer duration infusions performed using the infusion devices. Where the time for additional infusion remain acceptable, it should inform the patient and the relative elongation with respect to many benefits that these devices provide for the care home.
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Master Thesis
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https://dumas.ccsd.cnrs.fr/dumas-00592391
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Submitted on : Thursday, May 12, 2011 - 11:46:35 AM
Last modification on : Tuesday, May 11, 2021 - 11:36:17 AM
Long-term archiving on: : Saturday, August 13, 2011 - 2:47:56 AM

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  • HAL Id : dumas-00592391, version 1

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Caroline Chapon-Grangeon. Étude in vitro de la durée d'écoulement de solutions antibiotiques préparées dans des diffuseurs portables élastomériques : effet du stockage au froid pendant trois à sept jours. Sciences pharmaceutiques. 2010. ⟨dumas-00592391⟩

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