. Inserm, Cancer et environnement. Collection Expertise collective, 2008.

J. E. Dick, Stem cell concepts renew cancer research, Blood, vol.112, issue.13, pp.4793-807, 2008.
DOI : 10.1182/blood-2008-08-077941

L. Llopis, Molecular biology and prognostic value in acute myloid leukemia. Hématologie, pp.426-469, 2009.

D. G. Gilliland, Molecular genetics of human leukemias: New insights into therapy, Seminars in Hematology, vol.39, issue.4, pp.6-11, 2002.
DOI : 10.1053/shem.2002.36921

J. M. Bennett, D. Catovsky, M. T. Daniel, G. Flandrin, D. A. Galton et al., Proposals for the Classification of the Acute Leukaemias French-American-British (FAB) Co-operative Group, British Journal of Haematology, vol.1, issue.4, pp.451-459, 1976.
DOI : 10.1111/j.1365-2141.1976.tb03563.x

N. L. Harris, E. S. Jaffe, J. Diebold, G. Flandrin, H. K. Muller-hermelink et al., The World Health Organization classification of neoplastic diseases of the hematopoietic and lymphoid tissues. Report of the Clinical Advisory Committee meeting, Ann Oncol, issue.12, pp.10-1419, 1997.

E. S. Jaffe, N. L. Harris, H. Stein, and J. W. Vardiman, Pathology and genetics of tumours of haematopoietic and lymphoid tissues. WHO health organization classification of tumours, 2001.

S. H. Swerdlow, . Campoe, N. L. Harris, E. S. Jaffe, S. A. Pileri et al., WHO classification of tumours of haematopoietic and lymphoid tissues. Fourth Ed, 2008.

M. C. Bene, G. Castoldi, W. Knapp, W. D. Ludwig, E. Matutes et al., Proposals for the immunological classification of acute leukemias. European Group for the Immunological Characterization of Leukemias (EGIL), Leukemia, issue.910, pp.1783-1789, 1995.

J. M. Bennett, D. Catovsky, M. T. Daniel, G. Flandrin, D. A. Galton et al., Proposed Revised Criteria for the Classification of Acute Myeloid Leukemia, Annals of Internal Medicine, vol.103, issue.4, pp.620-625, 1985.
DOI : 10.7326/0003-4819-103-4-620

T. Nosslinger, R. Reisner, E. Koller, H. Gruner, H. Tuchler et al., Myelodysplastic syndromes, from French-American-British to World Health Organization: comparison of classifications on 431 unselected patients from a single institution, Blood, vol.98, issue.10, pp.98-2935, 2001.
DOI : 10.1182/blood.V98.10.2935

F. Valensi, Classification des leuc??mies aigu??s. Apport des propositions de l'Organisation mondiale de la sant??, EMC - H??matologie, vol.1, issue.1, 2003.
DOI : 10.1016/S1155-1984(03)00051-7

J. Pullen, J. J. Shuster, M. Link, M. Borowitz, M. Amylon et al., Significance of commonly used prognostic factors differs for children with T cell acute lymphocytic leukemia (ALL), as compared to those with B-precursor ALL. A Pediatric Oncology Group (POG) study, Leukemia, vol.13, issue.11, pp.13-1696, 1999.
DOI : 10.1038/sj.leu.2401555

J. M. Peters and M. Q. Ansari, Multiparameter flow cytometry in the diagnosis and management of acute leukemia, Arch Pathol Lab Med, vol.135, issue.1, pp.44-54, 2011.

H. Merle-béral, L. Garff-tavernier, and M. , Immunoph??notypage des h??mopathies malignes par cytom??trie de flux, EMC - H??matologie, vol.3, issue.3, pp.13-13, 2008.
DOI : 10.1016/S1155-1984(08)47155-8

D. Campana, Minimal Residual Disease in Acute Lymphoblastic Leukemia, Seminars in Hematology, vol.46, issue.1, pp.100-106, 2009.
DOI : 10.1053/j.seminhematol.2008.09.001

W. Kern, U. Bacher, C. Haferlach, S. Schnittger, and T. Haferlach, The role of multiparameter flow cytometry for disease monitoring in AML, Best Practice & Research Clinical Haematology, vol.23, issue.3, pp.379-90, 2010.
DOI : 10.1016/j.beha.2010.06.007

H. Jouault, Place de la cytométrie en flux pour le diagnostic et le suivi des leucémies aiguës. Revue Française des Laboratoires, pp.25-30, 2002.
DOI : 10.1016/s0338-9898(02)80017-8

M. J. Borowitz, M. C. Béné, N. L. Harris, A. Porwit, E. Matutes et al., Acute leukaemias of ambiguous lineage WHO classification of tumours of haematopoietic and lymphoid tissues. Fourth Ed, pp.24-1392, 2008.

O. K. Weinberg and D. A. Arber, Mixed-phenotype acute leukemia: historical overview and a new definition, Leukemia, vol.7, issue.11, pp.24-1844, 2010.
DOI : 10.1182/blood-2004-04-1616

X. Troussard, V. Duchenet, E. Cornet, D. Mouchel, M. Malet et al., Haematological malignancies: incidence in Basse, pp.57-151, 1997.

A. Belot, P. Grosclaude, N. Bossard, E. Jougla, E. Benhamou et al., Cancer incidence and mortality in France over the period 1980-2005. Rev Epidemiol Sante Publique, 25. Hospices civils de Lyon, Institut national de veille sanitaire, pp.159-75, 2008.
URL : https://hal.archives-ouvertes.fr/hal-00538673

B. Deschler and M. Lubbert, Acute myeloid leukemia: epidemiology and etiology. Cancer, pp.2099-107, 2006.

M. Brionne and M. Nowoczyn, Leucémies Aiguës Myéloïdes -Nouvelle classification OMS. Laboratoire Hématologie -CHU Caen, 2009.

X. Troussard and N. Maarouf, Biphenotypic leukaemia (BAL) : myth, reality, prospects. Spectra biologie, pp.34-38, 2006.

M. S. Linet, L. A. Ries, M. A. Smith, R. E. Tarone, and S. S. Devesa, Cancer Surveillance Series: Recent Trends in Childhood Cancer Incidence and Mortality in the United States, JNCI Journal of the National Cancer Institute, vol.91, issue.12, pp.91-1051, 1999.
DOI : 10.1093/jnci/91.12.1051

M. Belson, B. Kingsley, and A. Holmes, Risk Factors for Acute Leukemia in Children: A Review, Environmental Health Perspectives, vol.115, issue.1, pp.138-183, 2007.
DOI : 10.1289/ehp.9023

C. Berger, B. Trombert-paviot, N. Mitton, D. Frappaz, C. Galambrun et al., Childhood cancer incidence and survival rates in the Rhone-Alpes regional paediatric registry 1987-1999, Arch Pediatr, issue.2, pp.13-121, 2006.

B. Lacour, A. Guyot-goubin, S. Guissou, S. Bellec, E. Desandes et al., Incidence of childhood cancer in France: National Children Cancer Registries, Eur J Cancer Prev, issue.3, pp.19-173, 2000.

J. Clavel, A. Goubin, M. F. Auclerc, A. Auvrignon, C. Waterkeyn et al., Incidence of childhood leukaemia and non-Hodgkin's lymphoma in France: National Registry of Childhood Leukaemia and Lymphoma, 1990-1999, Eur J Cancer Prev, issue.2, pp.13-97, 2004.

Y. L. Kwong, Azathioprine: Association with Therapy-related Myelodysplastic Syndrome and Acute Myeloid Leukemia, The Journal of Rheumatology, vol.37, issue.3, pp.485-90, 2010.
DOI : 10.3899/jrheum.090834

J. W. Clark, M. Robert-guroff, O. Ikehara, E. Henzan, and W. A. Blattner, Human T-cell leukemia-lymphoma virus type 1 and adult T-cell leukemia-lymphoma in Okinawa, Cancer Res, issue.6, pp.45-2849, 1985.

J. R. Kerr, F. Barah, V. S. Cunniffe, J. Smith, P. J. Vallely et al., Association of acute parvovirus B19 infection with new onset of acute lymphoblastic and myeloblastic leukaemia, Journal of Clinical Pathology, vol.56, issue.11, pp.56-873, 2003.
DOI : 10.1136/jcp.56.11.873

S. Bhatia and C. Sklar, SECOND CANCERS IN SURVIVORS OF CHILDHOOD CANCER, Nature Reviews Cancer, vol.95, issue.2, pp.124-156, 2002.
DOI : 10.1056/NEJM199908053410607

S. De-botton, Leucémies aiguës myéloblastiques et syndromes myélodysplasiques induits. Hématologie, pp.16-20, 2010.

G. Leone, L. Pagano, D. Ben-yehuda, and M. T. Voso, Therapy-related leukemia and myelodysplasia: susceptibility and incidence, Haematologica, vol.92, issue.10, pp.92-1389, 2007.
DOI : 10.3324/haematol.11034

L. Pagano, A. Pulsoni, L. Mele, G. Leone, M. E. Tosti et al., Acute leukemia following a previous malignancy: do acute lymphoid leukemia and acute myeloid leukemia have common risk factors?, The Hematology Journal, vol.1, issue.5, pp.329-361, 2000.
DOI : 10.1038/sj.thj.6200058

J. W. Vardiman, D. A. Arber, R. D. Brunning, R. A. Larson, E. Matutes et al., Therapy-related myeloid neoplasms, Fourth Ed. WHO classification of tumours of haematopoietic and lymphoid tissues, pp.127-136, 2008.

C. A. Felix, Secondary leukemias induced by topoisomerase-targeted drugs, Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, vol.1400, issue.1-3, pp.233-55, 1998.
DOI : 10.1016/S0167-4781(98)00139-0

J. Libura, D. J. Slater, C. A. Felix, and C. Richardson, Therapy-related acute myeloid leukemia-like MLL rearrangements are induced by etoposide in primary human CD34+ cells and remain stable after clonal expansion, Blood, vol.105, issue.5, pp.105-2124, 2005.
DOI : 10.1182/blood-2004-07-2683

C. D. Bloomfield, K. J. Archer, K. Mrozek, D. M. Lillington, Y. Kaneko et al., 11q23 balanced chromosome aberrations in treatment-related myelodysplastic syndromes and acute leukemia: Report from an International Workshop???, Genes, Chromosomes and Cancer, vol.305, issue.Suppl, pp.362-78, 2002.
DOI : 10.1002/gcc.10046

J. M. Allan, A. G. Smith, K. Wheatley, R. K. Hills, L. B. Travis et al., Genetic variation in XPD predicts treatment outcome and risk of acute myeloid leukemia following chemotherapy, Blood, vol.104, issue.13, pp.104-3872, 2004.
DOI : 10.1182/blood-2004-06-2161

R. A. Larson, Y. Wang, M. Banerjee, J. Wiemels, C. Hartford et al., Prevalence of the inactivating 609C-->T polymorphism in the NAD(P)H:quinone oxidoreductase (NQO1) gene in patients with primary and therapy-related myeloid leukemia, Blood, issue.2, pp.94-803, 1999.

J. H. Folley, W. Borges, and T. Yamawaki, Incidence of leukemia in survivors of the atomic bomb in Hiroshima and Nagasaki, Japan, The American Journal of Medicine, vol.13, issue.3, pp.311-332, 1952.
DOI : 10.1016/0002-9343(52)90285-4

D. L. Preston, D. A. Pierce, Y. Shimizu, H. M. Cullings, S. Fujita et al., Effect of Recent Changes in Atomic Bomb Survivor Dosimetry on Cancer Mortality Risk Estimates, Radiation Research, vol.162, issue.4, pp.377-89, 2004.
DOI : 10.1667/RR3232

D. L. Preston, S. Kusumi, M. Tomonaga, S. Izumi, E. Ron et al., Cancer incidence in atomic bomb survivors. Part III. Leukemia, lymphoma and multiple myeloma, Radiat Res, issue.2, pp.137-68, 1950.

D. Laurier, S. Jacob, M. O. Bernier, K. Leuraud, C. Metz et al., Epidemiological studies of leukaemia in children and young adults around nuclear facilities: a critical review, Radiation Protection Dosimetry, vol.132, issue.2, pp.132-182, 2008.
DOI : 10.1093/rpd/ncn262

O. Guye, M. Bernard, A. Sonko, M. Dreneau, I. Fontanier et al., en collaboration avec les ORS Languedoc-Roussillon et Provence-Alpes-Côte-d'Azur et la Fnors (Fédération nationale des Observatoires Régionaux) de la Santé, Etude sanitaire sur les cancers autour du site nucléaire du Tricastin Risk of childhood cancer from fetal irradiation, Br J Radiol, vol.70, pp.130-139, 1997.

R. Wakeford and M. P. Little, Risk coefficients for childhood cancer after intrauterine irradiation: a review, International Journal of Radiation Biology, vol.103, issue.5, pp.79-293, 2003.
DOI : 10.1080/0955300031000114729

E. Ron, Cancer risks from medical radiation Ionizing radiation, part 2: some internally deposited radionuclides. Views and expert opinions of an IARC Working Group on the Evaluation of Carcinogenic Risks to Humans Impact sanitaire du radon domestique : de la connaissance à l'action. Bulletin épidémiologique hebdomadaire, Health Phys IARC Monogr Eval Carcinog Risks Hum, vol.85, issue.57, pp.47-59, 2000.

D. Laurier, M. Valenty, and M. Tirmarche, RADON EXPOSURE AND THE RISK OF LEUKEMIA, Health Physics, vol.81, issue.3, pp.81-272, 2001.
DOI : 10.1097/00004032-200109000-00009

A. S. Evrard, D. Hemon, S. Billon, D. Laurier, E. Jougla et al., Ecological association between indoor radon concentration and childhood leukaemia incidence in France, Eur J Cancer Prev, issue.2, pp.14-147, 1990.
URL : https://hal.archives-ouvertes.fr/inserm-00086147

O. Raaschou-nielsen, Indoor radon and childhood leukaemia, Radiation Protection Dosimetry, vol.132, issue.2, pp.175-81, 2008.
DOI : 10.1093/rpd/ncn288

URL : http://rpd.oxfordjournals.org/cgi/content/short/132/2/175

. Irsn, Campagne nationale de mesure de l'exposition domestique au radon, 2000.

A. Ahlbom, N. Day, M. Feychting, E. Roman, J. Skinner et al., A pooled analysis of magnetic fields and childhood leukaemia, British Journal of Cancer, vol.83, issue.5, pp.83-692, 2000.
DOI : 10.1054/bjoc.2000.1376

S. Greenland, A. R. Sheppard, W. T. Kaune, C. Poole, and M. A. Kelsh, A pooled analysis of magnetic fields, wire codes, and childhood leukemia. Childhood Leukemia-EMF Study Group, Epidemiology, issue.6, pp.11-624, 2000.

G. Draper, T. Vincent, M. E. Kroll, and J. Swanson, Childhood cancer in relation to distance from high voltage power lines in England and Wales: a case-control study, BMJ, vol.330, issue.7503, pp.330-1290, 2005.
DOI : 10.1136/bmj.330.7503.1290

L. Kheifets, J. D. Bowman, H. Checkoway, M. Feychting, J. M. Harrington et al., Future needs of occupational epidemiology of extremely low frequency electric and magnetic fields: review and recommendations, Occupational and Environmental Medicine, vol.66, issue.2, pp.66-72, 2009.
DOI : 10.1136/oem.2007.037994

H. Austin, E. Delzell, and P. Cole, BENZENE AND LEUKEMIA, American Journal of Epidemiology, vol.127, issue.3, pp.419-458, 1988.
DOI : 10.1093/oxfordjournals.aje.a114820

P. Guenel, E. Imbernon, A. Chevalier, A. Crinquand-calastreng, and M. Goldberg, Leukemia in relation to occupational exposures to benzene and other agents: a casecontrol study nested in a cohort of gas and electric utility workers, Am J Ind Med, issue.2, pp.42-87, 2002.

O. Wong, Risk of acute myeloid leukaemia and multiple myeloma in workers exposed to benzene., Occupational and Environmental Medicine, vol.52, issue.6, pp.380-384, 1995.
DOI : 10.1136/oem.52.6.380

D. A. Savitz and K. W. Andrews, Review of epidemiologic evidence on benzene and lymphatic and hematopoietic cancers, Am J Ind Med, issue.3, pp.31-287, 1997.

D. C. Glass, C. N. Gray, D. J. Jolley, C. Gibbons, M. R. Sim et al., Leukemia risk associated with low-level benzene exposure Final report on carcinogens background document for styrene, Epidemiology Rep Carcinog Backgr Doc, vol.14, issue.72, pp.569-778, 2003.

D. W. Kaufman, T. E. Anderson, and S. Issaragrisil, Risk factors for leukemia in Thailand, Annals of Hematology, vol.156, issue.suppl 6
DOI : 10.1007/s00277-009-0731-9

N. Sathiakumar, E. Delzell, M. Hovinga, M. Macaluso, J. A. Julian et al., Mortality from cancer and other causes of death among synthetic rubber workers, Occupational and Environmental Medicine, vol.55, issue.4, pp.55-230, 1998.
DOI : 10.1136/oem.55.4.230

J. F. Viel and S. T. Richardson, Adult leukemia and farm practices: An alternative approach for assessing geographical pesticide exposure, Social Science & Medicine, vol.32, issue.9, pp.1067-73, 1991.
DOI : 10.1016/0277-9536(91)90165-9

F. Menegaux, A. Baruchel, Y. Bertrand, B. Lescoeur, G. Leverger et al., Household exposure to pesticides and risk of childhood acute leukaemia, Occupational and Environmental Medicine, vol.63, issue.2, pp.131-135, 2006.
DOI : 10.1136/oem.2005.023036

URL : https://hal.archives-ouvertes.fr/inserm-00085342

J. Rudant, F. Menegaux, G. Leverger, A. Baruchel, B. Nelken et al., Household exposure to pesticides and risk of childhood hematopoietic malignancies: The ESCALE study (SFCE) Environ Health Perspect, pp.115-1787, 2007.

G. Van-maele-fabry, A. C. Lantin, P. Hoet, and D. Lison, Childhood leukaemia and parental occupational exposure to pesticides: a systematic review and meta-analysis, Cancer Causes & Control, vol.52, issue.6, pp.787-809, 2011.
DOI : 10.1007/s10552-010-9516-7

. Insee, Evolution et structure de la population -Chiffres clés -Drôme (26 - Département), 2010.

. Insee, Evolution et structure de la population -Chiffres clés -Ardèche (07 - Département), 2010.

J. Laganier and D. Vienne, Recensement de la population de, p.6, 1218.

. Insee, . La-lettre-résultats, and . Insee, Recommandation de la Commission, du 21 février 1990, relative à la protection de la population contre les dangers résultant de l'exposition au radon à l'intérieur des bâtiments, Euratom, vol.107, issue.90143, pp.3-26, 1990.

D. Circulaire-conjointe and . Vs5, 46 du 27 janvier 1999 relative à l'organisation de la gestion du risque lié au radon. Direction Générale de la Santé (DGS) et Conseil Supérieur d'Hygiène Publique de France (CSHPF), 1999. 85. Impact sanitaire du radon domestique : de la connaissance à l'action, Bulletin Epidémiologique Hebdomadaire, pp.18-19, 2007.

L. Rayonnements-ionisants-et-le-radon, Observatoire Régional de la Santé Rhône- Alpes (ORS), pp.1-19, 2007.

. Site, Classification Internationale Type de Professions CITP-88 Site internet: http://laborsta.ilo.org/applv8/data/isco88f, Consulté le 16 janvier 2011. 89. Valleron A.J., UE4 -évaluation des méthodes d'analyse appliquées aux sciences de la vie et de la santé, 2010.

E. L. Kaplan and P. Meier, Nonparametric Estimation from Incomplete Observations, Journal of the American Statistical Association, vol.37, issue.282, pp.457-481, 1958.
DOI : 10.1214/aoms/1177731566

A. Bélot, M. Velten, P. Grosclaude, N. Bossard, G. Launoy et al., Estimation nationale de l'incidence et de la mortalité par cancer en France entre Saint-Maurice (Fra) : Institut de veille sanitaire, Décembre 2008: 138. 92. Hospices civils de Lyon, Institut national de veille sanitaire, Institut national du cancer, Francim, Institut national de la santé et de la recherche médicale, Projections de l'incidence et de la mortalité par cancer en France en, Septembre 2009. 93. Estimations de population et statistiques de l'état civil. Site internet, 1980.

B. D. Cheson, J. M. Bennett, K. J. Kopecky, T. Buchner, C. L. Willman et al., Revised Recommendations of the International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid Leukemia, Journal of Clinical Oncology, vol.21, issue.24, pp.21-4642, 2003.
DOI : 10.1200/JCO.2003.04.036

H. Dohner, E. H. Estey, S. Amadori, F. R. Appelbaum, T. Buchner et al., Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet, Blood, vol.115, issue.3, pp.115-453, 2010.
DOI : 10.1182/blood-2009-07-235358

. Le-registre-des-hémopathies-malignes-de-la-gironde, Site internet: http://etudes.isped.u-bordeaux2.fr/registres-cancers- aquitaine/HM/H_Resultats.aspx -Consulté le 12, 2002.

U. Bacher, W. Kern, S. Schnittger, W. Hiddemann, C. Schoch et al., Further correlations of morphology according to FAB and WHO classification to cytogenetics in de novo acute myeloid leukemia: a study on 2,235 patients, Annals of Hematology, vol.100, issue.1, pp.84-785, 2005.
DOI : 10.1007/s00277-005-1099-0

F. Mugneret, P. Callier, and B. Favre-audry, Chromosomal abnormalities in acute myeloid leukaemias, Pathol Biol, issue.6, pp.51-314, 2003.

L. A. Godley and R. A. Larson, Therapy-Related Myeloid Leukemia, Seminars in Oncology, vol.35, issue.4, pp.418-447, 2008.
DOI : 10.1053/j.seminoncol.2008.04.012

L. Pagano, A. Pulsoni, M. E. Tosti, G. Avvisati, L. Mele et al., Clinical and biological features of acute myeloid leukaemia occurring as second malignancy: GIMEMA archive of adult acute leukaemia, British Journal of Haematology, vol.11, issue.1, pp.109-126, 2001.
DOI : 10.1016/S1040-8428(97)10029-4

S. M. Smith, L. Beau, M. M. Huo, D. Karrison, T. Sobecks et al., Clinical-cytogenetic associations in 306 patients with therapy-related myelodysplasia and myeloid leukemia: the University of Chicago series, Blood, vol.102, issue.1, pp.43-52, 2003.
DOI : 10.1182/blood-2002-11-3343

B. S. Preiss, O. J. Bergman, L. S. Friis, A. G. Sorensen, M. Frederiksen et al., Cytogenetic findings in adult secondary acute myeloid leukemia (AML): frequency of favorable and adverse chromosomal aberrations do not differ from adult de novo AML, Cancer Genetics and Cytogenetics, vol.202, issue.2, pp.202-108, 2010.
DOI : 10.1016/j.cancergencyto.2010.06.013

J. S. Brown, D. Eraut, C. Trask, and A. G. Davison, Age and the treatment of lung cancer., Thorax, vol.51, issue.6, pp.51-564, 1996.
DOI : 10.1136/thx.51.6.564

N. Mauritzson, M. Albin, L. Rylander, R. Billstrom, T. Ahlgren et al., Pooled analysis of clinical and cytogenetic features in treatment-related and de novo adult acute myeloid leukemia and myelodysplastic syndromes based on a consecutive series of 761 patients analyzed 1976-1993 and on 5098 unselected cases reported in the literature, pp.16-2366, 1974.

C. Aul, A. Giagounidis, U. Germing, and A. Ganser, Evaluating the prognosis of patients with myelodysplastic syndromes, Ann Hematol, issue.9, pp.81-485, 2002.

N. Dastugue, C. Payen, M. Lafage-pochitaloff, P. Bernard, D. Leroux et al., Prognostic significance of karyotype in de novo adult acute myeloid leukemia. The BGMT group, Leukemia, issue.99, pp.1491-1499, 1995.

K. Mrozek, N. A. Heerema, and C. D. Bloomfield, Cytogenetics in acute leukemia, Blood Reviews, vol.18, issue.2, pp.115-151, 2004.
DOI : 10.1016/S0268-960X(03)00040-7

M. Lafage-pochitaloff and C. Charrin, Cytogenetic abnormalities in acute lymphoblastic leukemia, Pathol Biol, issue.6, pp.51-329, 2003.

I. Luquet, J. L. Lai, C. Barin, L. Baranger, C. Bilhou-nabera et al., Hyperdiploid karyotypes in acute myeloid leukemia define a novel entity: a study of 38 patients from the Groupe Francophone de Cytogenetique Hematologique (GFCH), Leukemia, vol.20, issue.1, pp.132-139, 2008.
DOI : 10.1038/sj.leu.2404974

N. Dastugue, The interest of standard and molecular cytogenetics for diagnosis of acute leukemia, Pathol Biol, issue.6, pp.51-337, 2003.

C. Schoch, W. Kern, A. Kohlmann, W. Hiddemann, S. Schnittger et al., Acute myeloid leukemia with a complex aberrant karyotype is a distinct biological entity characterized by genomic imbalances and a specific gene expression profile, Genes, Chromosomes and Cancer, vol.53, issue.3, pp.43-227, 2005.
DOI : 10.1002/gcc.20193

G. Gohring, K. Michalova, H. B. Beverloo, D. Betts, J. Harbott et al., Complex karyotype newly defined: the strongest prognostic factor in advanced childhood myelodysplastic syndrome, Blood, vol.116, issue.19, pp.116-3766, 2010.
DOI : 10.1182/blood-2010-04-280313

C. H. Pui, A. J. Carroll, D. Head, S. C. Raimondi, J. J. Shuster et al., Neartriploid and near-tetraploid acute lymphoblastic leukemia of childhood, Blood, issue.3, pp.76-590, 1990.

D. Grimwade, A. Biondi, M. J. Mozziconacci, A. Hagemeijer, R. Berger et al., Characterization of acute promyelocytic leukemia cases lacking the classic t(15;17): results of the European Working Party, Blood, issue.4, pp.96-1297, 2000.

V. I. Gaidzik, R. F. Schlenk, S. Moschny, A. Becker, L. Bullinger et al., mutations in cytogenetically normal acute myeloid leukemia: a study of the German-Austrian AML Study Group, Blood, vol.113, issue.19, pp.113-4505, 2009.
DOI : 10.1182/blood-2008-10-183392

H. A. Hou, T. C. Huang, L. I. Lin, C. Y. Liu, C. Y. Chen et al., WT1 mutation in 470 adult patients with acute myeloid leukemia: stability during disease evolution and implication of its incorporation into a survival scoring system, Blood, vol.115, issue.25, pp.115-5222, 2010.
DOI : 10.1182/blood-2009-12-259390

P. Paschka, G. Marcucci, A. S. Ruppert, S. P. Whitman, K. Mrozek et al., Wilms??? Tumor 1 Gene Mutations Independently Predict Poor Outcome in Adults With Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study, Journal of Clinical Oncology, vol.26, issue.28
DOI : 10.1200/JCO.2007.15.2058

A. Renneville, N. Boissel, V. Zurawski, L. Llopis, V. Biggio et al., Wilms tumor 1 gene mutations are associated with a higher risk of recurrence in young adults with acute myeloid leukemia, Cancer, vol.8, issue.16, pp.115-3719, 2009.
DOI : 10.1002/cncr.24442

P. Virappane, R. Gale, R. Hills, I. Kakkas, K. Summers et al., Mutation of the Wilms??? Tumor 1 Gene Is a Poor Prognostic Factor Associated With Chemotherapy Resistance in Normal Karyotype Acute Myeloid Leukemia: The United Kingdom Medical Research Council Adult Leukaemia Working Party, Journal of Clinical Oncology, vol.26, issue.33, pp.26-5429, 2008.
DOI : 10.1200/JCO.2008.16.0333

H. Becker, G. Marcucci, K. Maharry, M. D. Radmacher, K. Mrozek et al., Mutations of the Wilms tumor 1 gene (WT1) in older patients with primary cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study, Blood, vol.116, issue.5, pp.116-788, 2010.
DOI : 10.1182/blood-2010-01-262543

P. A. Ho, R. Zeng, T. A. Alonzo, R. B. Gerbing, K. L. Miller et al., Prevalence and prognostic implications of WT1 mutations in pediatric acute myeloid leukemia (AML): a report from the Children's Oncology Group, Blood, vol.116, issue.5, pp.116-702, 2010.
DOI : 10.1182/blood-2010-02-268953

D. Cilloni, E. Gottardi, D. Micheli, D. Serra, A. Volpe et al., Quantitative assessment of WT1 expression by real time quantitative PCR may be a useful tool for monitoring minimal residual disease in acute leukemia patients, Leukemia, vol.16, issue.10, pp.16-2115, 2002.
DOI : 10.1038/sj.leu.2402675

J. M. Bennett, M. L. Young, J. W. Andersen, P. A. Cassileth, M. S. Tallman et al., Long-term survival in acute myeloid leukemia, Cancer, vol.15, issue.S11, pp.80-2205, 1997.
DOI : 10.1002/(SICI)1097-0142(19971201)80:11+<2205::AID-CNCR7>3.0.CO;2-G

A. Pulsoni, L. Pagano, R. Latagliata, M. Casini, R. Cerri et al., Survival of elderly patients with acute myeloid leukemia, Haematologica, issue.3, pp.89-296, 2004.

C. Schoch, W. Kern, S. Schnittger, W. Hiddemann, and T. Haferlach, Karyotype is an independent prognostic parameter in therapy-related acute myeloid leukemia (t-AML): an analysis of 93 patients with t-AML in comparison to 1091 patients with de novo AML, Leukemia, vol.18, issue.1, pp.120-125, 2004.
DOI : 10.1038/sj.leu.2403187

H. Halalsheh, N. Abuirmeileh, R. Rihani, F. Bazzeh, L. Zaru et al., Outcome of childhood acute lymphoblastic leukemia in Jordan, Pediatric Blood & Cancer, vol.53, issue.3, 2011.
DOI : 10.1002/pbc.23065

D. Botton, S. Fenaux, P. Quesnel, and B. , Prognosis factors for acute leukemias and lymphomas. Réanimation, pp.306-322, 2002.

H. Hussein, I. Sidhom, S. A. Naga, M. Amin, E. Ebied et al., Outcome and Prognostic Factors of Acute Lymphoblastic Leukemia in Children at the National Cancer Institute, Egypt, Journal of Pediatric Hematology/Oncology, vol.26, issue.8, pp.26-507, 2004.
DOI : 10.1097/01.mph.0000132735.93396.92

J. Dich, S. H. Zahm, and A. Hanberg, Adami H.O. Pesticides and cancer, Cancer Causes and Control, vol.8, issue.3, pp.420-463, 1997.
DOI : 10.1023/A:1018413522959

L. Miligi, A. S. Costantini, A. Veraldi, A. Benvenuti, and P. Vineis, Cancer and Pesticides: An Overview and Some Results of the Italian Multicenter Case-Control Study on Hematolymphopoietic Malignancies, Annals of the New York Academy of Sciences, vol.778, issue.19, pp.366-77, 2006.
DOI : 10.1093/annhyg/mef011

A. Amigou, C. Sermage-faure, L. Orsi, G. Leverger, A. Baruchel et al., Road Traffic and Childhood Leukemia: The ESCALE Study (SFCE) Environ Health Perspect, 2010.

C. R. Muirhead, Exposure assessment: implications for epidemiological studies of ionizing radiation, Radiation Protection Dosimetry, vol.132, issue.2, pp.134-142, 2008.
DOI : 10.1093/rpd/ncn267

D. Black, Chairman of the Independent Advisory Group) Investigation of the possible increased incidence of cancer in West Cumbria, 1984.

B. Grosche, Leucémies infantiles dans le voisinage des centrales nucléaires en Allemagne. Symposium sur les agrégats de leucémie. Actes du symposium, Commission de Contrôle de l'Energie Atomique Pub, pp.19-25, 1992.