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Master Thesis

Suivi de grossesse de femmes atteintes du Syndrome de Marfan. A propos d'une série rétrospective à l'Hôpital Bichat

Abstract : Objective: To study the occurrence of cardiac, obstetric, fetal and neonatal complications in pregnant women with the Marfan Syndrome. Results: 16 women had a total of 20 pregnancies resulting in 1 late miscarriage, one intra-uterine fetal death, 4 preterm and 14 at-term deliveries. Of the 18 births of viable children 16 were born by Caesarean Section and 2 by vaginal delivery. One major cardiac complication occurred during the study: an aortic dissection at 37 weeks in a woman whose pregnancy was cons-reported and for which treatment with beta-blockers was started at 35 weeks. 8 intra-uterine growth retardations were diagnosed during pregnancy and 7 children were born small for gestational age. Neonatal complications were found related to maternal treatment with beta-blockers: 1 bradycardia, 1 hypoglycemia, and 1 respiratory distress. For women affected by the Marfan syndrome, when the aortic diameter is less than 45 mm, pregnancy can be reasonably considered in establishing a joint obstetrical and cardiologic follow-up and a therapy with beta-blockade.
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https://dumas.ccsd.cnrs.fr/dumas-00623492
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Submitted on : Wednesday, September 14, 2011 - 1:50:39 PM
Last modification on : Friday, October 23, 2020 - 4:49:23 PM
Long-term archiving on: : Thursday, December 15, 2011 - 2:21:59 AM

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  • HAL Id : dumas-00623492, version 1

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Agathe Dumont. Suivi de grossesse de femmes atteintes du Syndrome de Marfan. A propos d'une série rétrospective à l'Hôpital Bichat. Gynécologie et obstétrique. 2011. ⟨dumas-00623492⟩

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