The Wisconsin epidemiologic study of diabetic retinopathy II. Prevalence and risk of diabetic retinopathy when age at diagnosis is less than 30 years, Arch Ophthalmol, vol.102, issue.1, pp.520-526, 1984. ,
Glycosylated Hemoglobin Predicts the Incidence and Progression of Diabetic Retinopathy, JAMA: The Journal of the American Medical Association, vol.260, issue.19, pp.2864-2871, 1988. ,
DOI : 10.1001/jama.1988.03410190112033
Glucose Control and the Renal and Retinal Complications of Insulin-dependent Diabetes, JAMA: The Journal of the American Medical Association, vol.261, issue.8, pp.1155-1160, 1989. ,
DOI : 10.1001/jama.1989.03420080075034
Current status of pancreatic islet transplantation, Clinical Science, vol.110, issue.6, pp.611-636, 2006. ,
DOI : 10.1042/CS20050342
Islet cell transplantation today. Langenbecks Arch Surg, pp.239-53, 2007. ,
DOI : 10.1007/s00423-007-0183-4
Islet Transplantation in Seven Patients with Type 1 Diabetes Mellitus Using a Glucocorticoid-Free Immunosuppressive Regimen, New England Journal of Medicine, vol.343, issue.4, 2000. ,
DOI : 10.1056/NEJM200007273430401
Five-Year Follow-Up After Clinical Islet Transplantation, Diabetes, vol.54, issue.7, pp.2060-2069, 2005. ,
DOI : 10.2337/diabetes.54.7.2060
A SELECTIVE DECREASE IN THE BETA CELL MASS OF HUMAN ISLETS TRANSPLANTED INTO DIABETIC NUDE MICE, Transplantation, vol.59, issue.6, pp.817-820, 1995. ,
DOI : 10.1097/00007890-199503000-00003
Factors influencing Islet of Langerhans graft function and monitoring, Clinica Chimica Acta, vol.310, issue.1, pp.3-16, 2001. ,
DOI : 10.1016/S0009-8981(01)00503-4
Mitochondria as the central control point of apoptosis. Trends in cell biology, pp.369-77, 2000. ,
The mitochondrial permeability transition Biochimica et biophysica acta, Jul, vol.17, issue.12412, pp.139-76, 1995. ,
Opening of the mitochondrial permeability transition pore induces reactive oxygen species production at the level of the respiratory chain complex I. The Journal of biological chemistry, pp.17197-204, 2004. ,
URL : https://hal.archives-ouvertes.fr/inserm-00389920
Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death, Nature, vol.65, issue.7033, pp.658-62, 2005. ,
DOI : 10.1038/sj.gt.3301048
Properties of the permeability transition pore in mitochondria devoid of Cyclophilin D. The Journal of biological chemistry, pp.18558-61, 2005. ,
The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore, Nature, vol.427, issue.6973, 2004. ,
DOI : 10.1038/nature02229
Regulation of the permeability transition pore in skeletal muscle mitochondria. Modulation by electron flow through the respiratory chain complex I. The Journal of biological chemistry, pp.12662-12670, 1998. ,
The characterization of mitochondrial permeability transition in clonal pancreatic beta-cells. Multiple modes and regulation. The Journal of biological chemistry, pp.41368-76, 2004. ,
The role of peripheral benzodiazepine receptors on the function and survival of isolated human pancreatic islets. European journal of endocrinology / European Federation of Endocrinology/European Federation of endocrine Societies, pp.207-221, 2004. ,
17-beta- Estradiol protects isolated human pancreatic islets against proinflammatory cytokineinduced cell death: molecular mechanisms and islet functionality, Transplantation, 2002. ,
DOI : 10.1097/00007890-200211150-00010
Cytokine-induced apoptosis and necrosis are preceded by disruption of the mitochondrial membrane potential (Deltapsi (m)) in pancreatic RINm5F cells: prevention by Bcl-2. Molecular and cellular endocrinology, pp.75-82, 2002. ,
NO induces a cGMP-independent release of cytochrome c from mitochondria which precedes caspase 3 activation in insulin producing RINm5F cells. FEBS letters, pp.238-281, 1999. ,
Specific inhibition of the mitochondrial permeability transition prevents lethal reperfusion injury, Journal of Molecular and Cellular Cardiology, vol.38, issue.2, pp.367-74, 2005. ,
DOI : 10.1016/j.yjmcc.2004.12.001
Desensitization of the permeability transition pore by cyclosporin a prevents activation of the mitochondrial apoptotic pathway and liver damage by tumor necrosis factor-alpha. The Journal of biological chemistry, pp.36803-36811, 2004. ,
Nitric oxide and mitochondria, Frontiers in Bioscience, vol.12, issue.1, pp.1024-1057, 2007. ,
DOI : 10.2741/2122
Metformin prevents high-glucose-induced endothelial cell death through a mitochondrial permeability transition-dependent process. Diabetes, pp.2179-87, 2005. ,
URL : https://hal.archives-ouvertes.fr/inserm-00388755
Establishment of 2- mercaptoethanol-dependent differentiated insulin-secreting cell lines, Endocrinology, 1992. ,
Effect of Transient and Permanent Permeability Transition Pore Opening on NAD(P)H Localization in Intact Cells, Biophysical Journal, vol.98, issue.3, pp.15117-15142, 2009. ,
DOI : 10.1016/j.bpj.2009.12.2036
URL : https://hal.archives-ouvertes.fr/inserm-00388526
Analysis of apoptosis by laser scanning cytometry, Cytometry, vol.32, issue.3, pp.181-95, 1999. ,
DOI : 10.1002/(SICI)1097-0320(19990301)35:3<181::AID-CYTO1>3.0.CO;2-5
Apoptosis and necrosis: Detection, discrimination and phagocytosis, Methods, vol.44, issue.3, pp.205-226, 2008. ,
DOI : 10.1016/j.ymeth.2007.12.001
Pancreatic Islets from Type 2 Diabetic Patients Have Functional Defects and Increased Apoptosis That Are Ameliorated by Metformin, The Journal of Clinical Endocrinology & Metabolism, vol.89, issue.11, pp.5535-5576, 2004. ,
DOI : 10.1210/jc.2004-0150
Metformin protects the ischemic heart by the Akt-mediated inhibition of mitochondrial permeability transition pore opening, Basic Research in Cardiology, vol.108, issue.Pt 3, pp.274-84, 2007. ,
DOI : 10.1007/s00395-007-0691-y
Activation of the Dual-Leucine-Zipper-Bearing Kinase and Induction of ??-Cell Apoptosis by the Immunosuppressive Drug Cyclosporin A, Molecular Pharmacology, vol.73, issue.3, pp.652-661, 2007. ,
DOI : 10.1124/mol.107.040782
Seven years of remission in a type I diabetic patient. Diabetes Care, pp.990-995, 1993. ,
Direct Effects of Cyclosporin A on Human Pancreatic ??-cells, Diabetes, vol.35, issue.9, pp.1049-1052, 1986. ,
DOI : 10.2337/diab.35.9.1049
The mitochondrial permeability transition, Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes, vol.1241, issue.2, pp.139-156, 1995. ,
DOI : 10.1016/0304-4157(95)00003-A
Mitochondria Are Excitable Organelles Capable of Generating and Conveying Electrical and Calcium Signals, Cell, vol.89, issue.7, pp.1145-1153, 1997. ,
DOI : 10.1016/S0092-8674(00)80301-3
Parallel Oscillations of Intracellular Calcium Activity and Mitochondrial Membrane Potential in Mouse Pancreatic B-Cells, Biochemical and Biophysical Research Communications, vol.267, issue.1, 2000. ,
DOI : 10.1006/bbrc.1999.1921
Diabetogenic Effect of Cyclosporin A Is Mediated by Interference with Mitochondrial Function of Pancreatic B- Cells Molecular Pharmacology, pp.873-879, 2001. ,
High Glucose Causes Apoptosis in Cultured Human Pancreatic Islets of Langerhans: A Potential Role for Regulation of Specific Bcl Family Genes Toward an Apoptotic Cell Death Program, Diabetes, vol.50, issue.6, pp.1290-301, 2001. ,
DOI : 10.2337/diabetes.50.6.1290
Glucose-induced ?? cell production of IL-1?? contributes to glucotoxicity in human pancreatic islets, Journal of Clinical Investigation, vol.110, issue.6, pp.851-60, 2002. ,
DOI : 10.1172/JCI200215318
Glucagon-Like Peptide 1 Inhibits Cell Apoptosis and Improves Glucose Responsiveness of Freshly Isolated Human Islets, Endocrinology, vol.144, issue.12, pp.5149-58, 2003. ,
DOI : 10.1210/en.2003-0323
Expectations and Strategies Regarding Islet Transplantation: Metabolic Data From the GRAGIL 2 Trial, Transplantation, vol.84, issue.1, pp.89-96, 2007. ,
DOI : 10.1097/01.tp.0000268511.64428.d8
URL : https://hal.archives-ouvertes.fr/hal-00201285
Plasma 15-F2t isoprostane concentrations are increased during acute fructose loading in type 2 diabetes. Diabetes Metab, pp.148-54, 2008. ,
Comparison of the effects of zinc alone and zinc associated with selenium and vitamin E on insulin sensitivity and oxidative stress in high-fructose-fed rats, Journal of Trace Elements in Medicine and Biology, vol.21, issue.2, pp.113-122, 2007. ,
DOI : 10.1016/j.jtemb.2006.12.005