Insulin: Discovery and controversy. Clinical Chemistry, pp.12-2270, 2002. ,
Physiologie de la sécrétion dinsuline: Physiology of insulin secretion, Médecine des Maladies Métaboliques, 2012. ,
Seventy-five years later, insulin remains Canada's major medical-research coup ,
7. Pancreatic Extracts in the Treatment of Diabetes Mellitus: Preliminary Report, CMAJ Nov, vol.15145, issue.10, pp.1281-1287, 1922. ,
DOI : 10.3138/9781442656918-011
Pancreatic Extracts in the Treatment of Diabetes Mellitus Can Med Assoc J, pp.141-147, 1922. ,
Lutilisation judicieuse de linsuline dans le traitement du diabète. Endocrinologie. Conférences scientifiques, JAMA, vol.4, issue.8, pp.90-610, 1928. ,
517525 DOI: 10.2515/therapie/2011073 13. em-consulte.com/article/22595/oedemes-generalises 14. cuen.fr 15 Bilateral pleural effusions, ascites, and facial and peripheral oedema in a 19-year-old woman 2 weeks following commencement of insulin lispro and detemir--an unusual presentation of insulin oedema, Thérapie 2011 Novembre-Décembre, pp.1282-1287, 2007. ,
Insulin-induced oedema in children and adolescents. J Paediatr Child Health, pp.655-662, 2006. ,
Insulin oedema: an uncommon complication of insulin therapy, J Assoc Physicians India, vol.39, issue.5, pp.411-423, 1991. ,
Insulin resistance and diabetic macular oedema in type 2 diabetes mellitus, British Journal of Ophthalmology, vol.94, issue.9, pp.1230-1232, 2010. ,
DOI : 10.1136/bjo.2009.171702
Insulin reverses haemodynamic changes and pulmonary oedema in children stung by the Indian red scorpion Mesobuthus tamulus concanesis, Pocock, Ann Trop Med Parasitol, 1991. ,
Insulin Oedema and its Clinical Significance: Metabolic Studies in Three Cases, Diabetic Medicine, vol.1, issue.3, pp.400-404, 1985. ,
DOI : 10.1111/j.1464-5491.1985.tb00663.x
Insulin oedema., Postgraduate Medical Journal, vol.62, issue.729 ,
DOI : 10.1136/pgmj.62.729.665
URL : http://pmj.bmj.com/cgi/content/short/62/729/665
Bilateral cataracts and insulin oedema in a child with type 1 ,
2013 Feb 1;2013. 24 Does the use of insulin in a patient with liver dysfunction increase water retention in the body, i.e. cause insulin oedema? ,
Parotid Gland Enlargement and the Insulin-oedema Syndrome, BMJ, vol.1, issue.5490 ,
DOI : 10.1136/bmj.1.5490.803-b
Diabetic (insulin) oedema., BMJ, vol.2, issue.6187, p.445, 1979. ,
DOI : 10.1136/bmj.2.6187.445-a
The insulin-oedema syndrome in African diabetic subjects, Transactions of the Royal Society of Tropical Medicine and Hygiene, vol.60, issue.4 ,
DOI : 10.1016/0035-9203(66)90277-X
Role of insulin in non-cardiac pulmonary oedema in scorpion stings, J Assoc Physicians India. Feb Bleach NR Br Med J. Jul Rabinowitch IM. INSULIN OEDEMA. Can Med Assoc J, vol.42217, issue.306, pp.171-173, 1927. ,
Cerebral oedema in diabetic ketoacidosis: do we use too much insulin? Lancet Involvement of the kinin system in the insulininduced inhibition of carrageenin oedema in rats, Monogr Allergy, vol.112, issue.8474, pp.131-138, 1977. ,
Contribution to the pathophysiology of protracted insulin coma and the concept of experimental model of cerebral oedema (author's transl)]. Bratisl Lek Listy, 1979. ,
Insulin edema in the twenty-first century: review of the existing literature, J Investig Med, vol.7152, issue.12, pp.3-15104, 2004. ,
Natural course of insulin edema, Journal of Endocrinological Investigation, vol.173, issue.3, pp.187-195, 2000. ,
DOI : 10.1007/BF03343704
Insulin edema in a child with diabetes mellitus type 1 Insulin edema in a patient with cystic fibrosis-related diabetes. Diabetes Care, Turk J Pediatr Feb, vol.5435, issue.372, pp.309-320, 2012. ,
Combined Insulin and Bicarbonate Therapy Elicits Cerebral Edema in a Juvenile Mouse Model of Diabetic Ketoacidosis, Pediatric Research, vol.31, issue.3, 2007. ,
DOI : 10.1203/pdr.0b013e318030d193
Case of insulin edema occurring during intensive insulin therapy after bone marrow transplantation, J Dermatol. Feb, vol.39, issue.2, pp.172-177, 2012. ,
Effective treatment of insulin-induced edema using ephedrine. Diabetes Care, pp.1026-1034, 1993. ,
Delayed insulin absorption due to subcutaneous edema ,
Generalized edema following insulin treatment of newly diagnosed diabetes mellitus. Tidsskr Nor Laegeforen Acute pulmonary edema caused by hypoglycemia due to insulin overdose, Intern Med, vol.12143, issue.811, pp.919-201056, 2001. ,
Insulin edema and Mauriac syndrome Med Clin (Barc) Insulin edema in three adolescents with insulin-dependent diabetes mellitus. Minerva Pediatr, Mar, vol.1712847, issue.10, 1995. ,
Gallbladder edema in type 1 diabetic patient due to delayed-type insulin allergy, Intern Med, vol.48, issue.17, pp.1545-1554, 2009. ,
Insulin edema in patients with diabetes mellitus and recent diabetic ketoacidosis (epidemiology and case reports) ,
A case of hypoglycemic brittle diabetes with peripheral edema successfully managed by conversion from insulin lispro to insulin aspart, Diabetes Res Clin Pract, vol.81, issue.83, pp.39-43, 2004. ,
Macular Edema and Pregnancy in Insulin-Dependent Diabetes, American Journal of Ophthalmology, vol.97, issue.2, pp.154-67, 1984. ,
DOI : 10.1016/S0002-9394(14)76085-4
Insulin edema in diabetes mellitus associated with the 3243 mitochondrial tRNA(Leu(UUR)) mutation; case reports, Diabetes Res Clin Pract, 1995. ,
A case of insulin edema with inappropriate hyperaldosteronism, Journal of Endocrinological Investigation, vol.68, issue.Suppl1, pp.957-60, 2004. ,
DOI : 10.1007/BF03347540
Insulin-induced cardiac failure, The American Journal of Medicine, vol.79, issue.1 ,
DOI : 10.1016/0002-9343(85)90562-5
Cause inhabituelle doedème chez une patiente diabétique: rôle de linsuline, Louvain Medical, vol.128, issue.7, pp.252-254, 2009. ,
Edema associated with improved glycemic control in an adolescent with type 1 diabetes. Clinical observations, J Pediatr, 1987. ,
Edematogenic syndrome in diabetics treated with insulin : a littke-known complication, Minerva Med. Feb, vol.18, issue.77, pp.5-6, 1986. ,
Epithelial sodium channels: function, structure, and regulation ,
Detailed Study of Electrolyte Balances Following the Withdrawal and Reestablishment of Insulin Therapy The effect of insulin on renal handling of sodium, potassium, calcium, and phosphate in man, J Clin Invest J Clin Invest, vol.12, issue.554, pp.297-326, 1933. ,
Insulin stimulates volume absorption in the rabbit proximal convoluted tubule., Journal of Clinical Investigation, vol.79, issue.4 ,
DOI : 10.1172/JCI112925
Insulin stimulates Na+, Cl-, Ca2+, and Mg2+ transports in TAL of mouse nephron: cross-potentiation with AVP, Am J Physiol, vol.265, issue.3 2, pp.361-370, 1993. ,
Insulin increases loop segment chloride reabsorption in the euglycemic rat, Am J Physiol, vol.255, issue.6, pp.1206-1219, 1988. ,
Pt 1): 171180 Hormonal regulation of ENaCs: insulin and aldosterone Insulin-stimulated trafficking of ENaC in renal cells requires PI 3-kinase activity, ATPase in rat collecting duct, pp.1645-53, 1995. ,
Hormonal regulation of the epithelial Na+ channel: From amphibians to mammals, General and Comparative Endocrinology, vol.147, issue.1, pp.85-92, 1998. ,
DOI : 10.1016/j.ygcen.2005.11.010
Stimulus-Dependent Regulation of Serum and Glucocorticoid Inducible Protein Kinase (SGK) Transcription, Subcellular Localization and Enzymatic Activity, Cellular Physiology and Biochemistry, vol.13, issue.1, pp.1-12, 2003. ,
DOI : 10.1159/000070244
Role of SGK in hormonal regulation of epithelial sodium channel in A6 cells, AJP: Cell Physiology, vol.284, issue.2, pp.404-418, 2003. ,
DOI : 10.1152/ajpcell.00398.2002
Activation of serum-and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide- dependent protein kinase-1 (PDK1) and PDK2, Biochem J. Apr, vol.15339, issue.2, pp.319-347, 1999. ,
Blunted hypertensive effect of combined fructose and high-salt diet in genetargeted mice lacking functional serum-and glucocorticoid-inducible kinase SGK1, Am J Physiol Regul Integr Comp Physiol, vol.290, issue.4, pp.935-979, 2006. ,
Coordinate expression of the PI3-kinase downstream effectors serum and glucocorticoid-induced kinase (SGK-1) and Akt-1 in human breast cancer, European Journal of Cancer, vol.41, issue.17, pp.2754-2763, 2005. ,
DOI : 10.1016/j.ejca.2005.07.018
Inducible kidney-specific Sgk1 knockout mice show a salt-losing phenotype, Am J Physiol Renal Physiol, vol.302, issue.8, pp.977-85, 2012. ,
Nedd4-2 modulates renal Na+-Cl-cotransporter via the aldosterone-SGK1-Nedd4-2 pathway, J Am Soc Nephrol, 2011. ,
Regulation of the epithelial sodium channel (ENaC) by membrane trafficking, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, vol.1802, issue.12, pp.1166-77, 1802. ,
DOI : 10.1016/j.bbadis.2010.03.010
Hormonal Regulation of the Epithelial Sodium Channel ENaC, The Journal of General Physiology, vol.280, issue.1 ,
DOI : 10.1046/j.1440-1681.2000.03204.x
Mechanisms of ENaC Regulation and Clinical Implications, Journal of the American Society of Nephrology, vol.19, issue.10 ,
DOI : 10.1681/ASN.2008020225
Trafficking of ENaC subunits in response to acute insulin in mouse kidney, AJP: Renal Physiology, vol.293, issue.1, pp.178-85, 2007. ,
DOI : 10.1152/ajprenal.00447.2006
Endothelial function and dysfunction: testing and clinical relevance. Circulation, Mar, vol.13115, issue.10, pp.1285-95, 2007. ,
The L-arginine-nitric oxide pathway, N Engl J Med, vol.329, issue.27, pp.2002-2014, 1993. ,
Mitochondria and Reactive Oxygen Species, Hypertension, vol.53, issue.6 ,
DOI : 10.1161/HYPERTENSIONAHA.109.130054
Endothelin-1: The Yin and Yang on Vascular Function, Current Medicinal Chemistry, vol.13, issue.14, pp.1655-65, 2006. ,
DOI : 10.2174/092986706777441968
Nitric oxide regulates the expression of vasoconstrictors and growth factors by vascular endothelium under both normoxia and hypoxia., Journal of Clinical Investigation, vol.92, issue.1, pp.99-104, 1993. ,
DOI : 10.1172/JCI116604
Insulin-mediated skeletal muscle vasodilation is nitric oxide dependent. A novel action of insulin to increase nitric oxide release., Journal of Clinical Investigation, vol.94, issue.3, pp.1172-1179, 1994. ,
DOI : 10.1172/JCI117433
Insulin-stimulated production of nitric oxide is inhibited by ,
Direct measurement in vascular endothelial cells, J Clin Invest Aug, vol.1598, issue.4, pp.894-902, 1996. ,
Insulin-induced vasodilatation: physiology or pharmacology?, Diabetologia, vol.41, issue.4, pp.369-79, 1998. ,
DOI : 10.1007/s001250050919
Molecular and physiologic actions of insulin related to production of nitric oxide in vascular endothelium, Current Diabetes Reports, vol.97, issue.suppl 2, pp.279-88, 2003. ,
DOI : 10.1007/s11892-003-0018-9
Regulation of blood flow in the microcirculation. Microcirculation, 2005. ,
Methodological aspects, dose-response characteristics and causes of interindividual variation in insulin stimulation of limb blood flow in normal subjects, Diabetologia, vol.43, issue.Suppl 1, pp.555-64, 1995. ,
DOI : 10.1007/BF00400724
Insulin as a Vascular and Sympathoexcitatory Hormone : Implications for Blood Pressure Regulation, Insulin Sensitivity, and Cardiovascular Morbidity, Circulation, vol.96, issue.11, pp.4104-4117, 1997. ,
DOI : 10.1161/01.CIR.96.11.4104
Mark AL Hyperinsulinemia produces both sympathetic neural activation and vasodilation in normal humans, J Clin Invest, 1991. ,
Effects of Sympathectomy and Nitric Oxide Synthase Inhibition on Vascular Actions of Insulin in Humans, Hypertension, vol.34, issue.4, pp.586-595, 1999. ,
DOI : 10.1161/01.HYP.34.4.586
Hypotensive and sedative effects of insulin in autonomic failure Baron AD, Brechtel G. Insulin differentially regulates systemic and skeletal muscle vascular resistancePhysiological' hyperinsulinaemia increases distal artery systolic blood pressure without changing proximal blood pressure, Br Med J (Clin Res Ed Am J Physiol. Clin Sci, vol.29526593, issue.1036, pp.161-164, 1987. ,
Diabetic Vascular Disease: An Experimental Objective, Arteriosclerosis, Thrombosis, and Vascular Biology, vol.26, issue.8 ,
DOI : 10.1161/01.ATV.0000231521.76545.f6
Edition John Libbey Eurotext ,
Vascular actions of insulin with implications for endothelial dysfunction, AJP: Endocrinology and Metabolism, vol.297, issue.3, pp.568-77, 2009. ,
DOI : 10.1152/ajpendo.00297.2009
Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation, Nature. Jun, vol.10399, issue.6736, pp.601-606, 1999. ,
Insulin-stimulated Activation of eNOS Is Independent of Ca2+ but Requires Phosphorylation by Akt at Ser1179, Journal of Biological Chemistry, vol.276, issue.32, pp.30392-30400, 2001. ,
DOI : 10.1074/jbc.M103702200
Insulin Signalling, Akt1 regulates pathological angiogenesis, pp.1188-96563, 1999. ,
DOI : 10.1016/S0898-6568(99)00025-X
The Pathobiology of Diabetic Complications: A Unifying Mechanism, Diabetes, vol.54, issue.6 ,
DOI : 10.2337/diabetes.54.6.1615
Vascular Endothelium: An Integrator of pathophysiologic Stimuli in Atherosclerosis, Arterioscler Thromb Vasc Biol, vol.17, pp.2479-2488, 1997. ,
Interactions ,