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Master Thesis

Place de l'oxygénothérapie hyperbare dans le traitement des gelures : évaluations des pratiques européennes

Abstract : Role of hyperbaric oxygen therapy in the treatment of frostbite: evaluation of common practices in Europe. Frostbite is a medical condition where the efficacy of hyperbaric oxygen therapy (HBOT) remains controversial and has not yet been proved scientifically. Frostbite is a tissue damage that occurs during prolonged and direct exposure to a temperature below 0°C. HBO is worth consideration as an adjunct therapy in frostbite management as it improves local oxygenation, reduces oedema, increases bactericidal activity and stimulates the healing process. Our study has been motivated by good clinical results in treatment of frostbites reported by the team of Hyperbaric Center in the Hospital of Sainte-Marguerite in Marseille. The main goal of this work was to describe the common practices while frostbite treatment in hyperbaric centers in Europe. Secondary endpoints were to verify if there was a therapeutic benefit of HBO in frostbite patients. Our questionnaire was sent to 134 hyperbaric chambers in Europe. 21 physicians completed the questionnaire. 86% of these specialists agreed that HBO could theoretically be indicated in frostbite treatment. Among the 25 patients included in the study, 84% were suffering from severe frostbites and only 44% received HBO in the first 72 hours. Despite these facts, during the first 3 months of evolution, 88% of patients showed improvement of skin lesions. Although the results did not meet statistical significance, these data suggest that using HBO as an adjunct therapy may be beneficial for patients suffering from frostbites, even at a late stage. Therefore, large prospective studies are necessary and justified.
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Master Thesis
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Edyta Kolakowska. Place de l'oxygénothérapie hyperbare dans le traitement des gelures : évaluations des pratiques européennes. Médecine humaine et pathologie. 2012. ⟨dumas-01000379⟩



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