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Master Thesis

Évaluation des pratiques professionnelles : étude de l'impact de l'humidification du Propess® sur son innocuité, son efficacité et son acceptabilité

Abstract : Evaluation of professional practices : the use of moistened Propess® : innocuity, efficacy and acceptability. About twenty percent of labors are induced in France since 1995. Propess® is one of the most frequently used ways of inducing labor. It's composed of natural prostaglandins. Many studies compared it with other methods, but there is no data about how to manipulate it. We tried to evaluate the use of moistened Propess® about it's innocuity, efficacy and acceptability. We observed that some midwives used water or other lubricating substances to insert the Propess®. Our study is both prospective and retrospective. Data were collected from two different hospitals during 2013 for eight month. 68 cases "dry" and 69 "moistening" were included. We analyzed results regarding both general population and small groups (primiparous, multiparous). It appears that labor is quicker in the primiparous (75% are in labor < 24h in the group "moistened", 55,9% in the group "dry", p=0.030). When the Propess® is dry, a second way of inducting labor is more needed than when it's moistened (p=0,008). When the Propess® is removed, there are more women in labor in the group "moistened" (37,5%) than in the group "dry" (17,6%, p=0,033). No significant difference was found regarding delivery and neonatal issues. Propess®'s moistening seems to be effective and it does not have more side effects. A randomized control study should be realized to verify this assessment. Moreover, since no explanation has been found, an in vitro study could be done to explain the mechanism.
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https://dumas.ccsd.cnrs.fr/dumas-01056874
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Submitted on : Wednesday, August 20, 2014 - 4:34:07 PM
Last modification on : Friday, October 23, 2020 - 4:49:22 PM
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  • HAL Id : dumas-01056874, version 1

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Diane Cousin. Évaluation des pratiques professionnelles : étude de l'impact de l'humidification du Propess® sur son innocuité, son efficacité et son acceptabilité. Gynécologie et obstétrique. 2014. ⟨dumas-01056874⟩

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