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Master Thesis

Étude des dopplers utérins au premier trimestre de la grossesse : comparaison de deux voies d'abord

Abstract : Study of Uterine Artery Doppler in the first trimester of pregnancy: comparison of two approaches. Preeclampsia, which affects about 2-7% of pregnancies, is a major cause of maternal and perinatal morbidity and mortality. In the first trimester of pregnancy, a screening of preeclampsia is proposed, based on patient age, personal and family history, pulsatility index (PI) of the uterine arteries, measurement of PAPP-A and the mean arterial pressure. Screening was created for uterine PI values obtained from transabdominal approach. However, this approach being sometimes difficult so the transvaginal approach is required. We can wonder if the use of a PI obtained from transvaginal in the screening is permitted. A study was conducted between March and April 2013 at the Necker Hospital on 176 women at 11 to 13 + 6 weeks of gestation. Uterine Doppler was performed from transabdominal and transvaginal approaches. A significant difference (p <0.05) was found between transabdominal PI (1.64) and transvaginal PI (1.55). However there were low correlation (R = 0.49). No corrective factor for integrating transvaginal PI could be developed due to a large dispersion of values. A larger scale study should be conducted in order to redefine standards of pathological transvaginal PI. This would allow integration from transvaginal PI to the screening.
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Submitted on : Thursday, September 4, 2014 - 3:20:09 PM
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  • HAL Id : dumas-01060910, version 1


Laure Tremolieres. Étude des dopplers utérins au premier trimestre de la grossesse : comparaison de deux voies d'abord. Gynécologie et obstétrique. 2014. ⟨dumas-01060910⟩



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