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Master Thesis

Contre-indications à l'altitude chez les sujets avec une maladie coronarienne ou un asthme : une revue de la littérature

Abstract : Background: More and more patients suffering from pre-existing conditions wish to spend some time at a high altitude and they are turning to the medical community to get their "safety pass". Purpose: Define clearly the contraindications related to an altitude of 2500m and above for patients who suffer from coronary heart disease or asthma. Methods: Review of the literature, inspired from the PRISMA methodology, searching the following data bases: Medline, Cismef, Cochrane Library, Google Scholar, SUDOC. The combination of the search terms: "altitude", "preexisting medical conditions", "coronary artery disease", "asthma" + limitation : "French or English" and "since 2003" has been used by Medline and is adapted to other data bases. The recommendations for the decision or not to allow a staying at a high altitude above 2500 m were synthesized, with the level of evidence. Results: 146 titles were found after the search in the data bases, and 21 articles were finally chosen and analyzed. The hand search have respectively produced 9 extra articles. Depending on their authors, the recommendations sometimes differ and have, on the whole, a low level of evidence, due to the lack of prospective studies devised to answer the given question. The pre-existing condition must be stable, low or moderately severe, in asymptomatic patients, who live at sea level, before the staying at a high altitude. Limitations: The main bias is that it was performed by only one researcher. Conclusion: based on this scientific literature, a consensus by experts using the Delphi methodology may be implemented in order to define new recommendations.
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Master Thesis
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Submitted on : Wednesday, October 8, 2014 - 10:03:21 AM
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  • HAL Id : dumas-01072403, version 1


Gwendoline Maroud Mingeon. Contre-indications à l'altitude chez les sujets avec une maladie coronarienne ou un asthme : une revue de la littérature. Médecine humaine et pathologie. 2014. ⟨dumas-01072403⟩



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