T. Habermas, Friderada: A case of miraculous fasting, International Journal of Eating Disorders, vol.17, issue.3, pp.555-62, 1986.
DOI : 10.1002/1098-108X(198603)5:3<555::AID-EAT2260050312>3.0.CO;2-G

M. R. Bell, anorexie sainte : jeûne et mysticisme du Moyen Âge à nos jours, 1994.

G. Raimbault, C. Eliacheff, A. Guillemot, and M. Laxenaire, Les indomptables. Figures de l'anorexie. Paris: Odile Jacob Anorexie mentale et boulimie. Le Poids de la culture, 1975.

C. Lasègue, De l'anorexie hyst??rique, Journal fran??ais de psychiatrie, vol.32, issue.1, pp.385-403, 1873.
DOI : 10.3917/jfp.032.0003

W. W. Gull, V.-Anorexia Nervosa (Apepsia Hysterica, Anorexia Hysterica), Obesity Research, vol.5, issue.5, p.22, 1874.
DOI : 10.1002/j.1550-8528.1997.tb00677.x

P. Jeammet, Paris: Doin, 1984.

J. E. Meyer and H. Feldmann, Anorexia Nervosa, Postgraduate Medicine, vol.4, issue.5, 1965.
DOI : 10.1146/annurev.me.14.020163.000551

S. Decobert, Survol historique de la notion d'anorexie mentale, Groupal, vol.7, pp.8-17, 2000.

B. Brusset, Psychopathologie de l'anorexie mentale. Édition : Coll. Psychismes. Paris: Dunod, 1998.

P. Jeammet, Psychopathologie des troubles des conduites alimentaires à l'adolescence. Valeur heuristique du concept de dépendance, Confront Psychiatr, vol.22, pp.177-202, 1989.

M. Corcos, Le corps insoumis -2ème ed. Paris: Dunod, 2011.
DOI : 10.3917/dunod.corco.2011.01

G. Agman, M. Corcos, and P. Jeammet, Troubles des conduites alimentaires Encycl Med Chir Psychiatrie, 37-350-A-10, p.16, 1994.

G. Agman, M. Corcos, D. Bochereau, J. Chambry, and P. Jeammet, Troubles des conduites alimentaires ?? l'adolescence, EMC - Psychiatrie, vol.1, issue.1, pp.37215-6515, 2002.
DOI : 10.1016/S0246-1072(02)00077-9

I. Nicolas, C. Lamas, and M. Corcos, Troubles des conduites alimentaires à l'adolescence, Encycl Med Chir Psychiatrie, vol.2013, pp.37-215

H. Autorité and D. Santé, Recommandations de Bonnes Pratiques Anorexie mentale; prise en charge, Paris : HAS, 2010.

O. Mondiale-de-la-santé-oms, Classification Internationale des Maladies et problèmes de santé connexes 10ème révision CIM-10, 1993.

A. Psychiatric-association and . Dsm-iv-tr, traduction française) Manuel diagnostique et statistique des troubles mentaux. Issy-les- Moulineaux: Masson, 2000.

H. W. Hoek, Incidence, prevalence and mortality of anorexia nervosa and other eating disorders, Current Opinion in Psychiatry, vol.19, issue.4, pp.389-94, 2006.
DOI : 10.1097/01.yco.0000228759.95237.78

K. A. Halmi, R. C. Casper, E. D. Eckert, S. C. Goldberg, and J. M. Davis, Unique Features associated with age of onset of anorexia nervosa, Psychiatry Research, vol.1, issue.2, pp.209-224, 1979.
DOI : 10.1016/0165-1781(79)90063-5

H. Roux, E. Chapelon, and N. Godart, ??pid??miologie de l???anorexie mentale??: revue de la litt??rature, L'Enc??phale, vol.39, issue.2, pp.85-93, 2013.
DOI : 10.1016/j.encep.2012.06.001

A. Preti, G. De-girolamo, G. Vilagut, J. Alonso, R. De-graaf et al., The epidemiology of eating disorders in six European countries: Results of the ESEMeD-WMH project, Journal of Psychiatric Research, vol.43, issue.14, pp.1125-1157, 2009.
DOI : 10.1016/j.jpsychires.2009.04.003

M. D. Keski-rahkonen, M. D. Hoek, M. D. Susser, B. M. Linna, M. D. Sihvola et al., Epidemiology and Course of Anorexia Nervosa in the Community, American Journal of Psychiatry, vol.164, issue.8, pp.1259-65, 2007.
DOI : 10.1176/appi.ajp.2007.06081388

A. Raevuori, H. W. Hoek, E. Susser, J. Kaprio, A. Rissanen et al., Epidemiology of Anorexia Nervosa in Men: A Nationwide Study of Finnish Twins, PLoS ONE, vol.4, issue.2, pp.4402-4403, 2009.
DOI : 10.1371/journal.pone.0004402.t001

J. I. Hudson, E. Hiripi, H. G. Pope, . Jr, and R. C. Kessler, The Prevalence and Correlates of Eating Disorders in the National Comorbidity Survey Replication, Biological Psychiatry, vol.61, issue.3, pp.348-58, 2007.
DOI : 10.1016/j.biopsych.2006.03.040

H. W. Hoek and D. Van-hoeken, Review of the prevalence and incidence of eating disorders, International Journal of Eating Disorders, vol.26, issue.4, pp.383-96, 2003.
DOI : 10.1002/eat.10222

D. M. Garner, Pathogenesis of anorexia nervosa, The Lancet, vol.341, issue.8861, pp.1631-1636, 1993.
DOI : 10.1016/0140-6736(93)90768-C

N. Godart, F. Perdereau, and P. Jeammet, Etiopathogénie des troubles des conduites alimentaires, Manuel de Psychiatrie, pp.424-454, 2007.

M. Strober, R. Freeman, C. Lampert, J. Diamond, and W. Kaye, Males with anorexia nervosa: A controlled study of eating disorders in first-degree relatives, International Journal of Eating Disorders, vol.157, issue.3, pp.263-272, 2001.
DOI : 10.1002/eat.1017

A. P. Pinheiro, T. Root, and C. M. Bulik, The genetics of anorexia nervosa: current findings and future perspectives, Int J Child Adolesc Health, vol.2, pp.153-64, 2009.

P. Jeammet, Vers une clinique de la dépendance Approche psychanalytique, Dépendance et conduites de consommation, pp.429-477, 1997.

M. Corcos, M. Flament, and P. Jeammet, Les conduites de dépendance : dimensions psychopathologiques communes, 2003.

D. A. Williamson, C. J. Davis, E. G. Duchmann, S. J. Mckenzie, and P. C. Watkins, Assessment of eating disorders: Obesity, anorexia, and bulimia nervosa, 1990.

S. Minuchin, L. Baker, B. L. Rosman, R. Liebman, L. Milman et al., A Conceptual Model of Psychosomatic Illness in Children, Archives of General Psychiatry, vol.32, issue.8, pp.1031-1039, 1975.
DOI : 10.1001/archpsyc.1975.01760260095008

M. Selvini-palazzoli, La famille de l'anorexique et la famille du schizophrène. Une étude transactionnelle, Actual Psychiatr, vol.12, pp.15-25, 1982.

P. Jeammet and A. Gorge, Une forme de thérapie familiale : le groupe de parents Bilan de six années de fonctionnement d'un groupe ouvert de parents d'anorexiques mentales adolescentes, Psychiatr Enfant, vol.23, pp.587-636, 1980.

P. Jeammet, Le groupe de parents : sa place dans le traitement de l'anorexie mentale, Neuropsychiatr Enfance Adolesc, vol.32, pp.299-303, 1984.

H. Steinhausen, The Outcome of Anorexia Nervosa in the 20th Century, American Journal of Psychiatry, vol.159, issue.8, pp.1284-93, 2002.
DOI : 10.1176/appi.ajp.159.8.1284

C. W. Sharp and C. P. Freeman, The medical complications of anorexia nervosa, The British Journal of Psychiatry, vol.162, issue.4, pp.452-62, 1993.
DOI : 10.1192/bjp.162.4.452

G. Hütter, S. Ganepola, and W. Hofmann, The hematology of anorexia nervosa, International Journal of Eating Disorders, vol.63, issue.4, pp.293-300, 2009.
DOI : 10.1002/eat.20610

R. Strumia, Dermatologic Signs in Patients with Eating Disorders, American Journal of Clinical Dermatology, vol.145, issue.8, pp.165-73, 2005.
DOI : 10.2165/00128071-200506030-00003

H. T. Chui, B. K. Christensen, R. B. Zipursky, B. A. Richards, M. K. Hanratty et al., Cognitive Function and Brain Structure in Females With a History of Adolescent-Onset Anorexia Nervosa, PEDIATRICS, vol.122, issue.2, pp.426-437, 2008.
DOI : 10.1542/peds.2008-0170

N. D. Berkman, K. N. Lohr, and C. M. Bulik, Outcomes of eating disorders: A systematic review of the literature, International Journal of Eating Disorders, vol.15, issue.4, pp.293-309, 2007.
DOI : 10.1002/eat.20369

N. T. Godart, M. F. Flament, F. Perdereau, and P. Jeammet, Comorbidity between eating disorders and anxiety disorders: A review, International Journal of Eating Disorders, vol.33, issue.3, pp.253-70, 2002.
DOI : 10.1002/eat.10096

N. T. Godart, F. Perdereau, Z. Rein, S. Berthoz, J. Wallier et al., Comorbidity studies of eating disorders and mood disorders. Critical review of the literature, Journal of Affective Disorders, vol.97, issue.1-3, pp.37-49, 2007.
DOI : 10.1016/j.jad.2006.06.023

N. Coulon, P. Jeammet, and N. Godart, Phobie sociale dans l???anorexie mentale??: ??volution au cours des soins, L'Enc??phale, vol.35, issue.6, pp.531-538, 2009.
DOI : 10.1016/j.encep.2008.09.005

D. K. Katzman, Medical complications in adolescents with anorexia nervosa: A review of the literature, International Journal of Eating Disorders, vol.111, issue.S1, pp.52-59, 2005.
DOI : 10.1002/eat.20118

C. Lamas, Troubles des conduites alimentaires et maternité-infertilité, Rev Prat, vol.58, issue.2, pp.147-155, 2008.

D. E. Stewart, R. E. Goldbloom, D. S. Wright, and C. , Infertility and eating disorders, American Journal of Obstetrics and Gynecology, vol.163, issue.4, pp.1196-1205, 1990.
DOI : 10.1016/0002-9378(90)90688-4

M. Freizinger, D. L. Franko, M. Dacey, B. Okun, and A. D. Domar, The prevalence of eating disorders in infertile women, Fertility and Sterility, vol.93, issue.1, pp.72-80, 2010.
DOI : 10.1016/j.fertnstert.2008.09.055

J. Arcelus, A. J. Mitchell, J. Wales, and S. Nielsen, Mortality Rates in Patients With Anorexia Nervosa and Other Eating Disorders, Archives of General Psychiatry, vol.68, issue.7, pp.724-755, 2011.
DOI : 10.1001/archgenpsychiatry.2011.74

P. F. Sullivan, Mortality in anorexia nervosa, Am J Psychiatr, vol.152, pp.1073-1077, 1995.

E. C. Harris and B. Barraclough, Excess mortality of mental disorder, The British Journal of Psychiatry, vol.173, issue.1, pp.11-53, 1998.
DOI : 10.1192/bjp.173.1.11

S. Zipfel, B. Löwe, D. L. Reas, H. C. Deter, and W. Herzog, Long-term prognosis in anorexia nervosa: lessons from a 21-year follow-up study, The Lancet, vol.355, issue.9205, pp.721-723, 2000.
DOI : 10.1016/S0140-6736(99)05363-5

. American-psychiatric-association, Treatment of Patients With Eating Disorders, Third Edition, Am J Psychiatry, vol.163, pp.4-54, 2006.
DOI : 10.1176/appi.books.9780890423363.138660

P. K. Keel and A. Haedt, Evidence-Based Psychosocial Treatments for Eating Problems and Eating Disorders, Journal of Clinical Child & Adolescent Psychology, vol.154, issue.1, pp.39-61, 2008.
DOI : 10.1002/1098-108X(199201)11:1<3::AID-EAT2260110103>3.0.CO;2-V

A. W. Hetherington and S. W. Ranson, Hypothalamic lesions and adiposity in the rat, The Anatomical Record, vol.88, issue.2, pp.149-72, 1940.
DOI : 10.1002/ar.1090780203

B. K. Anand and J. R. Brobeck, Localization of a "Feeding Center" in the Hypothalamus of the Rat, Experimental Biology and Medicine, vol.77, issue.2, pp.323-327, 1951.
DOI : 10.3181/00379727-77-18766

S. P. Kalra, M. G. Dube, P. Shuye, X. Bin, L. H. Tamas et al., Interacting appetiteregulating pathways in the hypothalamic regulation of body weight, Endocr Rev, vol.20, pp.68-100, 1999.

B. Stanley, S. E. Kyrkouli, S. Lampert, and S. F. Leibowitz, Neuropeptide Y chronically injected into the hypothalamus: A powerful neurochemical inducer of hyperphagia and obesity, Peptides, vol.7, issue.6, pp.1189-92, 1986.
DOI : 10.1016/0196-9781(86)90149-X

T. M. Hahn, J. F. Breininger, D. G. Baskin, and M. W. Schwartz, Coexpression of Agrp and NPY in fasting-activated hypothalamic neurons, Nat Neurosci, vol.1, pp.271-273, 1998.

R. Poggioli, A. V. Vergoni, and A. Bertolini, ACTH-(1???24) and ??-MSH antagonize feeding behavior stimulated by kappa opiate agonists, Peptides, vol.7, issue.5, pp.843-851, 1986.
DOI : 10.1016/0196-9781(86)90104-X

C. F. Elias, C. Lee, J. Kelly, C. Aschkenasi, R. S. Ahima et al., Leptin Activates Hypothalamic CART Neurons Projecting to the Spinal Cord, Neuron, vol.21, issue.6, pp.1375-85, 1998.
DOI : 10.1016/S0896-6273(00)80656-X

C. Broberger, J. Johansen, C. Johansson, M. Schalling, and T. Hökfelt, The neuropeptide Y/agouti gene-related protein (AGRP) brain circuitry in normal, anorectic, and monosodium glutamate-treated mice, Proceedings of the National Academy of Sciences, vol.95, issue.25, pp.15043-15051, 1998.
DOI : 10.1073/pnas.95.25.15043

B. G. Stanley and S. F. Leibowitz, Neuropeptide Y injected in the paraventricular hypothalamus: a powerful stimulant of feeding behavior., Proceedings of the National Academy of Sciences, vol.82, issue.11, pp.3940-3943, 1985.
DOI : 10.1073/pnas.82.11.3940

Y. Hu, B. T. Bloomquist, L. J. Cornfield, L. B. Decarr, J. Flores-riveros et al., Identification of a novel hypothalamic neuropeptide Y receptor associated with feeding behavior, J Biol Chem, vol.271, pp.26315-26324, 1996.

A. Kanatani, M. Hata, S. Mashiko, A. Ishihara, O. Okamoto et al., A typical Y1 receptor regulates feeding behaviors: effects of a potent and selective Y1 antagonist, J-115814, Mol Pharmacol, vol.59, pp.501-506, 2001.

A. Sahu, P. S. Kalra, and S. P. Kalra, Food deprivation and ingestion induce reciprocal changes in neuropeptide Y concentrations in the paraventricular nucleus, Peptides, vol.9, issue.1, pp.83-89, 1988.
DOI : 10.1016/0196-9781(88)90013-7

A. Thorsell and M. Heilig, Diverse functions of neuropeptide Y revealed using genetically modified animals, Neuropeptides, vol.36, issue.2-3, pp.182-93, 2002.
DOI : 10.1054/npep.2002.0897

M. M. Ollmann, B. D. Wilson, Y. Yang, J. A. Kerns, Y. Chen et al., Antagonism of Central Melanocortin Receptors in Vitro and in Vivo by Agouti-Related Protein, Science, vol.278, issue.5335, pp.135-143, 1997.
DOI : 10.1126/science.278.5335.135

D. Lu, D. Willard, I. R. Patel, S. Kadwell, L. Overton et al., Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor, Nature, vol.371, issue.6500, pp.799-802, 1994.
DOI : 10.1038/371799a0

J. E. Mcminn, C. W. Wilkinson, P. J. Havel, S. C. Woods, and M. W. Schwartz, Effect of intracerebroventricular ?-MSH on food intake, adiposity, c-Fos induction, and neuropeptide expression, Am J Physiol Regul Integr Comp Physiol, vol.279, pp.695-703, 2000.

H. Krude, H. Biebermann, D. Schnabel, M. Z. Tansek, P. Theunissen et al., Obesity Due to Proopiomelanocortin Deficiency: Three New Cases and Treatment Trials with Thyroid Hormone and ACTH4???10, The Journal of Clinical Endocrinology & Metabolism, vol.88, issue.10, pp.4633-4673, 2003.
DOI : 10.1210/jc.2003-030502

C. Vaisse, K. Clement, E. Durand, S. Hercberg, B. Guy-grand et al., Melanocortin-4 receptor mutations are a frequent and heterogeneous cause of morbid obesity, Journal of Clinical Investigation, vol.106, issue.2, pp.253-62, 2000.
DOI : 10.1172/JCI9238

P. Kristensen, M. E. Judge, L. Thim, U. Ribel, K. N. Christjansen et al., Hypothalamic CART is a new anorectic peptide regulated by leptin, Nature, vol.393, issue.6680, pp.72-78, 1998.
DOI : 10.1038/29993

C. R. Abbott, M. Rossi, A. M. Wren, K. G. Murphy, A. R. Kennedy et al., Evidence of an Orexigenic Role for Cocaine- and Amphetamine-Regulated Transcript after Administration into Discrete Hypothalamic Nuclei, Endocrinology, vol.142, issue.8, pp.3457-63, 2001.
DOI : 10.1210/endo.142.8.8304

M. W. Schwartz, S. C. Woods, D. Porte, . Jr, R. J. Seeley et al., Central nervous system control of food intake, Nature, vol.404, pp.661-71, 2000.

D. Qu, D. S. Ludwig, S. Gammeltoft, M. Piper, M. A. Pelleymounter et al., A role for melanin-concentrating hormone in the central regulation of feeding behaviour, Nature, vol.380, issue.6571, pp.243-250, 1996.
DOI : 10.1038/380243a0

M. Székely, E. Pétervári, M. Balaskó, I. Hernádi, and B. Uzsoki, Effects of orexins on energy balance and thermoregulation, Regulatory Peptides, vol.104, issue.1-3, pp.47-53, 2002.
DOI : 10.1016/S0167-0115(01)00348-2

H. Ferner, The insular alpha and beta cells as the source of the antagonistic principles glucagon and insulin], Mikroskopie, vol.6, pp.1-8, 1951.

S. C. Woods, E. C. Lotter, L. D. Mckay, and D. Porte, Chronic intracerebroventricular infusion of insulin reduces food intake and body weight of baboons, Nature, vol.3, issue.5738, pp.503-508, 1979.
DOI : 10.1016/0031-9384(77)90218-9

L. E. Pritchard, A. V. Turnbull, and A. White, Pro-opiomelanocortin processing in the hypothalamus: impact on melanocortin signalling and obesity, Journal of Endocrinology, vol.172, issue.3, pp.411-432, 2002.
DOI : 10.1677/joe.0.1720411

Y. Zhang, R. Proenca, M. Maffei, M. Barone, L. Leopold et al., Positional cloning of the mouse obese gene and its human homologue, Nature, vol.372, issue.6505, pp.425-457, 1994.
DOI : 10.1038/372425a0

M. Maffei, J. Halaas, E. Ravussin, R. E. Pratley, G. H. Lee et al., Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects, Nature Medicine, vol.132, issue.11, pp.1155-61, 1995.
DOI : 10.1006/abio.1987.9999

L. A. Campfield, F. J. Smith, Y. Guisez, R. Devos, and P. Burn, Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks, Science, vol.269, issue.5223, pp.546-555, 1995.
DOI : 10.1126/science.7624778

D. G. Baskin, J. F. Breininger, and M. W. Schwartz, Leptin receptor mRNA identifies a subpopulation of neuropeptide Y neurons activated by fasting in rat hypothalamus, Diabetes, vol.48, issue.4, pp.828-861, 1999.
DOI : 10.2337/diabetes.48.4.828

J. M. Lundberg, K. Tatemoto, L. Terenius, P. M. Hellström, V. Mutt et al., Localization of peptide YY (PYY) in gastrointestinal endocrine cells and effects on intestinal blood flow and motility., Proceedings of the National Academy of Sciences, vol.79, issue.14, pp.4471-4476, 1982.
DOI : 10.1073/pnas.79.14.4471

R. L. Batterham, M. A. Cowley, C. J. Small, H. Herzog, M. A. Cohen et al., Gut hormone PYY3-36 physiologically inhibits food intake, Nature, vol.281, issue.6898, pp.650-654, 2002.
DOI : 10.1016/S0306-4522(00)00308-0

G. Rindi, A. Torsello, V. Locatelli, and E. Solcia, Ghrelin expression and actions: a novel peptide for an old cell type of the diffuse endocrine system, Exp Biol Med Maywood NJ, vol.229, pp.1007-1023, 2004.

M. Nakazato, N. Murakami, Y. Date, M. Kojima, H. Matsuo et al., A role for ghrelin in the central regulation of feeding, Nature, vol.409, issue.6817, pp.194-202, 2001.
DOI : 10.1038/35051587

L. Wang, D. H. Saint-pierre, and Y. Taché, Peripheral ghrelin selectively increases Fos expression in neuropeptide Y ??? synthesizing neurons in mouse hypothalamic arcuate nucleus, Neuroscience Letters, vol.325, issue.1, pp.47-51, 2002.
DOI : 10.1016/S0304-3940(02)00241-0

E. E. Müller, A. Panerai, D. Cocchi, L. A. Frohman, and P. Mantegazza, Central glucoprivation: Some physiological effects induced by the intraventricular administration of 2-deoxy-d-glucose, Experientia, vol.20, issue.7, pp.874-880, 1973.
DOI : 10.1007/BF01946338

S. H. Cha, M. Wolfgang, Y. Tokutake, S. Chohnan, and M. D. Lane, Differential effects of central fructose and glucose on hypothalamic malonyl-CoA and food intake, Proceedings of the National Academy of Sciences, vol.105, issue.44, pp.16871-16876, 2008.
DOI : 10.1073/pnas.0809255105

I. Bady, N. Marty, M. Dallaporta, M. Emery, J. Gyger et al., Evidence From Glut2-Null Mice That Glucose Is a Critical Physiological Regulator of Feeding, Diabetes, vol.55, issue.4, pp.988-95, 2006.
DOI : 10.2337/diabetes.55.04.06.db05-1386

F. Daddoun and M. Romon, R??gulation physiologique du comportement alimentaire, Cahiers de Nutrition et de Di??t??tique, vol.39, issue.6, pp.422-450, 2008.
DOI : 10.1016/S0007-9960(04)94483-5

A. Volterra and J. Meldolesi, Astrocytes, from brain glue to communication elements: the revolution continues, Nature Reviews Neuroscience, vol.21, issue.8, pp.626-666, 2005.
DOI : 10.1038/35077000

H. Shinoda, A. M. Marini, C. Cosi, and J. P. Schwartz, Brain region and gene specificity of neuropeptide gene expression in cultured astrocytes, Science, vol.245, issue.4916, pp.415-422, 1989.
DOI : 10.1126/science.2569236

E. Guillod-maximin, A. Lorsignol, T. Alquier, and L. Pénicaud, Acute Intracarotid Glucose Injection Towards the Brain Induces Specific c-fos Activation in Hypothalamic Nuclei: Involvement of Astrocytes in Cerebral Glucose-Sensing in Rats, Journal of Neuroendocrinology, vol.16, issue.5, pp.464-71, 2004.
DOI : 10.1111/j.1365-2826.2004.01185.x

URL : https://hal.archives-ouvertes.fr/hal-00409148

D. Hulst, C. Atack, J. R. Kooy, and R. F. , The complexity of the GABA A receptor shapes unique pharmacological profiles, Drug Discov Today, vol.14, pp.866-75, 2009.

C. Braestrup and R. F. Squires, Specific benzodiazepine receptors in rat brain characterized by high-affinity (3H)diazepam binding., Proceedings of the National Academy of Sciences, vol.74, issue.9, pp.3805-3814, 1977.
DOI : 10.1073/pnas.74.9.3805

R. F. Squires and C. Braestrup, Benzodiazepine receptors in rat brain, Nature, vol.14, issue.5604, pp.732-736, 1977.
DOI : 10.1038/266732a0

A. Guidotti, C. M. Forchetti, M. G. Corda, D. Konkel, C. D. Bennett et al., Isolation, characterization, and purification to homogeneity of an endogenous polypeptide with agonistic action on benzodiazepine receptors., Proceedings of the National Academy of Sciences, vol.80, issue.11, pp.3531-3536, 1983.
DOI : 10.1073/pnas.80.11.3531

M. A. Debernardi, R. R. Crowe, I. Mocchetti, T. B. Shows, R. L. Eddy et al., Chromosomal localization of the human diazepam binding inhibitor gene., Proceedings of the National Academy of Sciences, vol.85, issue.17, pp.6561-6566, 1988.
DOI : 10.1073/pnas.85.17.6561

J. V. Swinnen, M. Esquenet, J. Rosseels, F. Claessens, W. Rombauts et al., A Human Gene Encoding Diazepam-Binding Inhibitor/Acyl-CoA-Binding Protein: Transcription and Hormonal Regulation in the Androgen-Sensitive Human Prostatic Adenocarcinoma Cell Line LNCaP, DNA and Cell Biology, vol.15, issue.3, pp.197-208, 1996.
DOI : 10.1089/dna.1996.15.197

M. Kolmer, A. Rovio, and H. Alho, The characterization of two diazepam binding inhibitor (DBI) transcripts in humans, Biochemical Journal, vol.306, issue.2, pp.327-357, 1995.
DOI : 10.1042/bj3060327

E. Slobodyansky, A. Guidotti, C. Wambebe, A. Berkovich, and E. Costa, Isolation and Characterization of a Rat Brain Triakontatetraneuropeptide, a Posttranslational Product of Diazepam Binding Inhibitor: Specific Action at the Ro 5-4864 Recognition Site, Journal of Neurochemistry, vol.7, issue.4, pp.1276-84, 1989.
DOI : 10.1016/0006-8993(76)90506-0

M. Tonon, L. Désy, P. Nicolas, H. Vaudry, and G. Pelletier, Immunocytochemical localization of the endogenous benzodiazepine ligand octadecaneuropeptide (ODN) in the rat brain, Neuropeptides, vol.15, issue.1, pp.17-24, 1990.
DOI : 10.1016/0143-4179(90)90155-R

J. A. Ball, M. A. Ghatei, K. Sekiya, T. Krausz, and S. R. Bloom, Diazepam binding inhibitor-like immunoreactivity(51???70): distribution in human brain, spinal cord and peripheral tissues, Brain Research, vol.479, issue.2, pp.300-305, 1989.
DOI : 10.1016/0006-8993(89)91632-6

J. Bormann and D. E. Clapham, gamma-Aminobutyric acid receptor channels in adrenal chromaffin cells: a patch-clamp study., Proceedings of the National Academy of Sciences, vol.82, issue.7, pp.2168-72, 1985.
DOI : 10.1073/pnas.82.7.2168

J. Bormann, Electrophysiological characterization of diazepam binding inhibitor (DBI) on GABAA receptors, Neuropharmacology, vol.30, issue.12, pp.1387-1396, 1991.
DOI : 10.1016/S0028-3908(11)80006-7

R. R. Anholt, P. L. Pedersen, E. B. Souza, and S. H. Snyder, The peripheral-type benzodiazepine receptor. Localization to the mitochondrial outer membrane, J Biol Chem, vol.261, pp.576-83, 1986.

H. Alho, V. Varga, and K. E. Krueger, Expression of mitochondrial benzodiazepine receptor and its putative endogenous ligand diazepam binding inhibitor in cultured primary astrocytes and C-6 cells: relation to cell growth, Cell Growth Differ, vol.5, p.1005, 1994.

C. Patte, H. Vaudry, L. Desrues, P. Gandolfo, I. Strijdveen et al., The endozepine ODN stimulates polyphosphoinositide metabolism in rat astrocytes, FEBS Letters, vol.131, issue.2, pp.106-116, 1995.
DOI : 10.1016/0014-5793(95)00209-R

V. Taupin, A. Herbelin, B. Descamps-latscha, and F. Zavala, Endogenous anxiogenic peptide, ODN-diazepam-binding inhibitor, and benzodiazepines enhance the production of interleukin-1 and tumor necrosis factor by human monocytes, Lymphokine Cytokine Res, vol.10, pp.7-13, 1991.

V. Taupin, S. Toulmond, A. Serrano, J. Benavides, and F. Zavala, Increase in IL-6, IL-1 and TNF levels in rat brain following traumatic lesion, Journal of Neuroimmunology, vol.42, issue.2, pp.177-85, 1993.
DOI : 10.1016/0165-5728(93)90008-M

M. Cosentino, F. Marino, S. Cattaneo, L. D. Grazia, C. Francioli et al., Diazepam-binding inhibitor-derived peptides induce intracellular calcium changes and modulate human neutrophil function, J Leukoc Biol, vol.67, pp.637-680, 2000.

F. Marino, M. Cosentino, A. M. Fietta, M. Ferrari, S. Cattaneo et al., Interleukin-8 production induced by the endozepine triakontatetraneuropeptide in human neutrophils: role of calcium and pharmacological investigation of signal transduction pathways, Cellular Signalling, vol.15, issue.5, pp.511-518, 2003.
DOI : 10.1016/S0898-6568(02)00134-1

K. Yanagibashi, Y. Ohno, M. Kawamura, and P. F. Hall, The Regulation of Intracellular Transport of Cholesterol in Bovine Adrenal Cells: Purification of a Novel Protein, Endocrinology, vol.123, issue.4, pp.2075-82, 1988.
DOI : 10.1210/endo-123-4-2075

V. Compère, S. Li, J. Leprince, M. Tonon, H. Vaudry et al., In vivo action of a new octadecaneuropeptide (ODN) antagonist on gonadotropin-releasing hormone gene expression in the male rat brain, Neuroscience, vol.125, issue.2, pp.411-416, 2004.
DOI : 10.1016/j.neuroscience.2004.02.016

L. Givalois, S. Li, and G. Pelletier, Role of Glucocorticoids in the Modulation of Corticotropin-Releasing Hormone mRNA Level by the Endogenous Benzodiazepine Receptor Ligand Octadecaneuropeptide in Rat Brain, Neuroendocrinology, vol.68, issue.2, pp.98-104, 1998.
DOI : 10.1159/000054355

R. Apfel, F. Lottspeich, J. Hoppe, C. Behl, G. Dürr et al., Purification and analysis of growth regulating proteins secreted by a human melanoma cell line, Melanoma Research, vol.2, issue.5, pp.327-363, 1992.
DOI : 10.1097/00008390-199212000-00006

M. Garnier, N. Boujrad, B. O. Oke, A. S. Brown, J. Riond et al., Diazepam binding inhibitor is a paracrine/autocrine regulator of Leydig cell proliferation and steroidogenesis: action via peripheral-type benzodiazepine receptor and independent mechanisms, Endocrinology, vol.132, pp.444-58, 1993.

M. L. Barbaccia, E. Costa, and P. Ferrero, Diazepam-Binding Inhibitor, Archives of General Psychiatry, vol.43, issue.12, pp.1143-1150, 1986.
DOI : 10.1001/archpsyc.1986.01800120029007

D. Mateos-verchere, J. Leprince, J. Tonon, M. Vaudry, H. Costentin et al., The Octadecaneuropeptide ODN Induces Anxiety in Rodents: Possible Involvement of a Shorter Biologically Active Fragment, Peptides, vol.19, issue.5, pp.841-849, 1998.
DOI : 10.1016/S0196-9781(98)00037-0

M. Kavaliers and M. Hirst, An octadecaneuropeptide (ODN) derived from diazepam binding inhibitor increases aggressive interactions in mice, Brain Research, vol.383, issue.1-2, pp.343-352, 1986.
DOI : 10.1016/0006-8993(86)90037-5

P. Ferrero, M. R. Santi, B. Conti-tronconi, E. Costa, and A. Guidotti, Study of an octadecaneuropeptide derived from diazepam binding inhibitor (DBI): biological activity and presence in rat brain., Proceedings of the National Academy of Sciences, vol.83, issue.3, pp.827-858, 1986.
DOI : 10.1073/pnas.83.3.827

D. Mateos-verchere, J. G. Leprince, J. Tonon, M. Vaudry, H. Costentin et al., The octadecaneuropeptide [diazepam-binding inhibitor (33???50)] exerts potent anorexigenic effects in rodents, European Journal of Pharmacology, vol.414, issue.2-3, pp.225-256, 2001.
DOI : 10.1016/S0014-2999(01)00771-3

V. Compère, S. Li, J. Leprince, M. Tonon, H. Vaudry et al., Effect of Intracerebroventricular Administration of the Octadecaneuropeptide on the Expression of Pro-Opiomelanocortin, Neuropeptide Y and Corticotropin-Releasing Hormone mRNAs in Rat Hypothalamus, Journal of Neuroendocrinology, vol.33, issue.2, pp.197-203, 2003.
DOI : 10.1046/j.1365-2826.2003.00970.x

D. Rego, J. Orta, M. Leprince, J. Tonon, M. Vaudry et al., Pharmacological Characterization of the Receptor Mediating the Anorexigenic Action of the Octadecaneuropeptide: Evidence for an Endozepinergic Tone Regulating Food Intake, Neuropsychopharmacology, vol.65, issue.7, pp.1641-1649, 2006.
DOI : 10.1038/sj.npp.1301280

D. Lanfray, S. Arthaud, J. Ouellet, V. Compère, J. D. Rego et al., Gliotransmission and Brain Glucose Sensing: Critical Role of Endozepines, Diabetes, vol.62, issue.3, pp.801-811, 2013.
DOI : 10.2337/db11-0785

Y. Li, Y. Hao, and C. Owyang, Diazepam-binding inhibitor mediates feedback regulation of pancreatic secretion and postprandial release of cholecystokinin, Journal of Clinical Investigation, vol.105, issue.3, pp.351-360, 2000.
DOI : 10.1172/JCI7204

P. Leichner, H. Steiger, G. Puentes-neuman, M. Perreault, and N. Gottheil, Validation d'une échelle d'attitudes alimentaires auprès d'une population québécoise francophone, Can J Psychiatry n.d, vol.39, pp.49-54

J. P. Lépine, M. Godchau, P. Brun, and T. Lempérière, Evaluation de l'anxiété et de la dépression chez des patients hospitalisés dans un service de médecine interne, Ann Méd Psychol, vol.143, pp.175-89, 1985.

M. Bouvard and J. Cottraux, Protocoles et échelles d'évaluation en psychiatrie et en psychologie, 2002.

H. Vaudry, M. Tonon, C. Delarue, R. Vaillant, and J. Kraicer, Biological and Radioimmunological Evidence for Melanocyte Stimulating Hormones (MSH) of Extrapituitary Origin in the Rat Brain, Neuroendocrinology, vol.27, issue.1-2, pp.9-24, 1978.
DOI : 10.1159/000122796

C. Duparc, H. Lefebvre, M. Tonon, H. Vaudry, and J. Kuhn, Characterization of Endozepines in the Human Testicular Tissue: Effect of Triakontatetraneuropeptide on Testosterone Secretion, The Journal of Clinical Endocrinology & Metabolism, vol.88, issue.11, pp.5521-5529, 2003.
DOI : 10.1210/jc.2003-030783

P. Jeammet, G. Brechon, C. Payan, A. Gorge, and J. Fermanian, Le devenir de l'anorexie mentale : une étude prospective de 129 patients évalués au moins 4 ans après leur première admission, Psychiatrie l'enf, vol.34, issue.2, pp.381-442, 1991.

L. K. Hsu, Outcome of early onset anorexia nervosa: What do we know?, Journal of Youth and Adolescence, vol.41, issue.4, pp.563-571, 1996.
DOI : 10.1007/BF01537549

H. Steinhausen, Annotation: Outcome of Anorexia Nervosa in the Younger Patient, Journal of Child Psychology and Psychiatry, vol.9, issue.3, pp.271-277, 1997.
DOI : 10.1007/BF01537547

W. Vandereycken, The place of inpatient care in the treatment of anorexia nervosa: Questions to be answered, International Journal of Eating Disorders, vol.31, issue.4, pp.409-431, 2003.
DOI : 10.1002/eat.10223

V. Narayanan, J. L. Gaudiani, and P. S. Mehler, Serum Albumin Levels May Not Correlate With Weight Status in Severe Anorexia Nervosa, Eating Disorders, vol.152, issue.4, pp.322-328, 2009.
DOI : 10.1097/01.CCM.0000215112.84523.F0

A. P. Winston, The clinical biochemistry of anorexia nervosa, Annals of Clinical Biochemistry: An international journal of biochemistry and laboratory medicine, vol.49, issue.2, pp.132-175, 2012.
DOI : 10.1258/acb.2011.011185

C. Ferrarese, T. Cogliati, R. Tortorella, C. Zucca, G. Bogliun et al., Diazepam binding inhibitor (DBI) in the plasma of pediatric and adult epileptic patients, Epilepsy Research, vol.29, issue.2, pp.129-163, 1998.
DOI : 10.1016/S0920-1211(97)00074-0

E. Conti, L. Tremolizzo, M. Bomba, O. Uccellini, M. S. Rossi et al., Reduced fasting plasma levels of diazepam-binding inhibitor in adolescents with anorexia nervosa, International Journal of Eating Disorders, vol.16, issue.6, 2013.
DOI : 10.1002/eat.22129

S. Y. Nam, J. Kratzsch, K. W. Kim, K. R. Kim, S. K. Lim et al., Cerebrospinal fluid and plasma concentrations of leptin, NPY, and alpha-MSH in obese women and their relationship to negative energy balance, J Clin Endocrinol Metab, vol.86, pp.4849-53, 2001.