U. and «. Pitons, cirques et remparts de l'ile de la Réunion » , [consulté en juillet 2014]; Disponible sur le web, 1317.

F. Michailesco, L. Grand, and H. , Difficultés face à l'écrit. INSEE Partenaires n°27; Octobre 2013

J. Rivière and V. «. Daudin, Informations Rapides Réunion n°300 » [En ligne]; Avril 2014, Disponible sur le web

H. Sauberlich, Laboratory Tests for the Assessment of Nutritional Status, Second Edition, p.12, 1999.

O. Fain, Carences en vitamine C. Rev Médecine Interne, pp.872-80, 2004.
DOI : 10.1016/j.revmed.2004.03.009

S. Hercberg, P. Galan, P. Preziosi, S. Bertrais, L. Mennen et al., The SU.VI.MAX Study, Archives of Internal Medicine, vol.164, issue.21, pp.2335-2377, 2004.
DOI : 10.1001/archinte.164.21.2335

URL : https://hal.archives-ouvertes.fr/hal-01346671

J. Hirschmann and G. Raugi, Adult scurvy, Journal of the American Academy of Dermatology, vol.41, issue.6, pp.895-910, 1999.
DOI : 10.1016/S0190-9622(99)70244-6

M. Levine, New Concepts in the Biology and Biochemistry of Ascorbic Acid, Journal of Nutritional Medicine, vol.46, issue.3-4, pp.892-902, 1986.
DOI : 10.3109/13590849208997993

A. Kierszenbaum, Histologie et biologie cellulaire : Une introduction à l'anatomie pathologique, pp.98-99, 2006.

S. Lioret, C. Dubuisson, A. Dufour, M. Touvier, G. Calamassi-tran et al., Trends in food intake in French children from 1999 to 2007: results from the INCA (??tude Individuelle Nationale des Consommations Alimentaires) dietary surveys, British Journal of Nutrition, vol.13, issue.04, pp.585-601, 2010.
DOI : 10.1159/000066398

«. Anses and . French, composition table version (2013) » [En ligne]; 2013. Disponible sur le web: <https://pro

J. Vanderslice and D. Higgs, Vitamin C content of foods: sample variability, Am J Clin Nutr, vol.54, issue.6, pp.1323-1327, 1991.

Y. Lim, T. Lim, and J. Tee, Antioxidant properties of guava fruit: comparison with some local fruits, Sunway Acad J, vol.3, pp.9-20, 2006.

. Afssa, Apports nutritionnels conseillés en vitamine C pour la population française » [En ligne] ; [consulté en 2014], Disponible sur le web : <www.afssa.fr

E. Magiorkinis, A. Beloukas, and A. Diamantis, Scurvy: Past, present and future, European Journal of Internal Medicine, vol.22, issue.2, pp.147-52, 2011.
DOI : 10.1016/j.ejim.2010.10.006

P. Aubry, Scurvy, an illness of mariners from the 15th to 18th century , always present. Médecine Trop Rev Corps Santé Colon, pp.478-80, 2001.

F. Assefa, M. Jabarkhil, P. Salama, and P. Spiegel, Malnutrition and Mortality in Kohistan District, Afghanistan, April 2001, JAMA, vol.286, issue.21, pp.2723-2731, 2001.
DOI : 10.1001/jama.286.21.2723

J. Desenclos, A. Berry, R. Padt, B. Farah, C. Segala et al., Epidemiological patterns of scurvy among Ethiopian refugees, Bull World Health Organ, vol.67, issue.3, pp.309-325, 1989.

J. Dillon, Prevention of iron deficiency and iron deficiency anemia in tropical areas, Médecine Trop Rev Corps Santé Colon, vol.60, issue.1, pp.83-91, 2000.

J. Hampl, C. Taylor, and C. Johnston, Vitamin C Deficiency and Depletion in the United States: The Third National Health and Nutrition Examination Survey, 1988 to 1994, American Journal of Public Health, vol.94, issue.5, pp.870-875, 1988.
DOI : 10.2105/AJPH.94.5.870

R. Riemersma, M. Oliver, R. Elton, G. Alfthan, E. Vartiainen et al., Plasma antioxidants and coronary heart disease: vitamins C and E, and selenium, Eur J Clin Nutr. Feb, vol.44, issue.2, pp.143-50, 1990.

S. Hercberg, P. Preziosi, P. Galan, M. Devanlay, H. Keller et al., Vitamin status of a healthy French population: dietary intakes and biochemical markers, Int J Vitam Nutr Res Int Z Für Vitam-Ernährungsforschung J Int Vitaminol Nutr, vol.64, issue.3, pp.220-252, 1994.

G. Policy, F. Ma, G. Security, H. , and S. , Nutrition and health in old age: the cross-sectional analysis of the findings of a survey made in 1972/3 of elderly people who had been, report. H.M. Stationery Off, vol.8, 1967.

O. Fain, J. Pariés, B. Jacquart, L. Moël, G. Kettaneh et al., Hypovitaminosis C in hospitalized patients, European Journal of Internal Medicine, vol.14, issue.7, pp.419-444, 2003.
DOI : 10.1016/j.ejim.2003.08.006

R. Hodges, E. Baker, J. Hood, H. Sauberlich, and S. March, Experimental Scurvy in Man, Am J Clin Nutr, vol.22, issue.5, pp.535-583, 1969.

C. Johnston and L. Thompson, Vitamin C Status of an Outpatient Population, Journal of the American College of Nutrition, vol.22, issue.4, pp.366-70, 1998.
DOI : 10.1080/07315724.1998.10718777

R. Jacob, J. Skala, and S. Omaye, Biochemical indices of human vitamin C status, Am J Clin Nutr, vol.46, issue.5, pp.818-844, 1987.

R. Hodges, J. Hood, J. Canham, H. Sauberlich, and E. Baker, Clinical manifestations of ascorbic acid deficiency in man, Am J Clin Nutr, vol.24, issue.4, pp.432-475, 1971.

B. Velandia, R. Centor, V. Mcconnell, and M. Shah, Scurvy Is Still Present in Developed Countries, Journal of General Internal Medicine, vol.44, issue.8, pp.1281-1285, 2008.
DOI : 10.1007/s11606-008-0577-1

F. Oski, . Beutler, . Ma-lichtman, &. Bs-coller, and . Kipps, Anemia due to other nutritional deficiencies, Williams' Hematology, pp.511-515, 1995.

A. Yalçin, A. Ural, C. Beyan, B. Ta?tan, M. Demiriz et al., SCURVY PRESENTING WITH CUTANEOUS AND ARTICULAR SIGNS AND DECREASE IN RED AND WHITE BLOOD CELLS, International Journal of Dermatology, vol.55, issue.12, pp.879-81, 1996.
DOI : 10.1016/0049-3848(81)90034-7

A. Goldberg, The Anaemia of Scurvy, QJM, vol.32, issue.1, pp.51-64, 1963.

E. Cox, M. Meynell, W. Cooke, and R. Gaddie, Scurvy and anaemia, Am J Med, 1962.
DOI : 10.1016/0002-9343(62)90293-0

R. Kinsman and J. Hood, Some behavioral effects of ascorbic acid deficiency, Am J Clin Nutr, vol.24, issue.4, pp.455-64, 1971.

H. Khonsari, L. Grandière-perez, and E. Caumes, Le scorbut n'a pas disparu : histoire d'une maladie réémergente. Rev Médecine Interne, pp.885-90, 2005.

G. Schectman, Estimating Ascorbic Acid Requirements for Cigarette Smokers, Annals of the New York Academy of Sciences, vol.34, issue.6, pp.335-380, 1993.
DOI : 10.1016/S0140-6736(66)92139-8

I. Hininger, M. Chopra, D. Thurnham, F. Laporte, M. Richard et al., Effect of increased fruit and vegetable intake on the susceptibility of lipoprotein to oxidation in smokers, European Journal of Clinical Nutrition, vol.51, issue.9, pp.601-607, 1997.
DOI : 10.1038/sj.ejcn.1600451

A. Kallner, D. Hartmann, and D. Hornig, On the requirements of ascorbic acid in man: steady-state turnover and body pool in smokers, Am J Clin Nutr, vol.34, issue.7, pp.1347-55, 1981.

O. Fain, E. Mathieu, and M. Thomas, Lesson of the week: Scurvy in patients with cancer, BMJ, vol.316, issue.7145, pp.1661-1663, 1998.
DOI : 10.1136/bmj.316.7145.1661

R. Lee, Scurvy: a contemporary historical perspective, Conn Med, 1983.

V. Fazio, D. Flint, and M. Wahlqvist, Acute effects of alcohol on plasma ascorbic acid in healthy subjects, Am J Clin Nutr, vol.34, issue.11, pp.2394-2400, 1981.

J. Cunningham, S. Ellis, K. Mcveigh, R. Levine, and J. Calles-escandon, Reduced mononuclear leukocyte ascorbic acid content in adults with insulin-dependent diabetes mellitus consuming adequate dietary vitamin C. Metabolism, Feb, vol.40, issue.2, pp.146-155, 1991.

I. Chatterjee and A. Banerjee, Estimation of dehydroascorbic acid in blood of diabetic patients, Analytical Biochemistry, vol.98, issue.2, pp.368-74, 1979.
DOI : 10.1016/0003-2697(79)90155-6

S. Som, S. Basu, D. Mukherjee, S. Deb, P. Choudhury et al., Ascorbic acid metabolism in diabetes mellitus, Metabolism, vol.30, issue.6, pp.572-579, 1981.
DOI : 10.1016/0026-0495(81)90133-5

M. Bürzle and M. Hediger, Chapter Eleven -Functional and Physiological Role of Vitamin C Transporters. Mark O. Bevensee, Current Topics in Membranes Academic Press; 2012, pp.357-75

A. Montel-hagen, S. Kinet, N. Manel, C. Mongellaz, R. Prohaska et al., Erythrocyte Glut1 Triggers Dehydroascorbic Acid Uptake in Mammals Unable to Synthesize Vitamin C. Cell, pp.1039-1087, 2008.

S. Kc, J. Cárcamo, and D. Golde, Vitamin C enters mitochondria via facilitative glucose transporter 1 (Glut1) and confers mitochondrial protection against oxidative injury, The FASEB Journal, vol.19, issue.12
DOI : 10.1096/fj.05-4107com

J. Cunningham, Altered vitamin C transport in diabetes mellitus. Med Hypotheses, 1988.

L. Stankova, M. Riddle, J. Larned, K. Burry, D. Menashe et al., Plasma ascorbate concentrations and blood cell dehydroascorbate transport in patients with diabetes mellitus. Metabolism, pp.347-53, 1984.

T. Connelly, A. Becker, and J. Mcdonald, Bachelor Scurvy, International Journal of Dermatology, vol.31, issue.4, pp.209-220, 1982.
DOI : 10.1111/j.1365-2133.1968.tb11911.x

A. Reddy, K. Chan, J. Jones, M. Vassallo, and M. Auger, Spontaneous bruising in an elderly woman., Postgraduate Medical Journal, vol.74, issue.871, pp.273-278, 1998.
DOI : 10.1136/pgmj.74.871.273

R. Jacob, C. Otradovec, R. Russell, H. Munro, S. Hartz et al., Vitamin C status and nutrient interactions in a healthy elderly population, Am J Clin Nutr, vol.48, issue.6, pp.1436-1478, 1988.

C. Bates, I. Rutishauser, A. Black, A. Paul, A. Mandal et al., Long-term vitamin status and dietary intake of healthy elderly subjects, British Journal of Nutrition, vol.59, issue.01, pp.43-56, 1979.
DOI : 10.1079/BJN19790088

C. Loria, P. Whelton, L. Caulfiled, M. Szklo, and M. Klag, Agreement among Indicators of Vitamin C Status, American Journal of Epidemiology, vol.147, issue.6, pp.587-96, 1998.
DOI : 10.1093/oxfordjournals.aje.a009491

A. Karlsen, R. Blomhoff, and T. Gundersen, Stability of whole blood and plasma ascorbic acid, European Journal of Clinical Nutrition, vol.204, issue.10, pp.1233-1239, 2007.
DOI : 10.1038/sj.ejcn.1602655

E. Nagy and I. Degrell, Determination of ascorbic acid and dehydroascorbic acid in plasma and cerebrospinal fluid by liquid chromatography with electrochemical detection, Journal of Chromatography B: Biomedical Sciences and Applications, vol.497, pp.276-81, 1989.
DOI : 10.1016/0378-4347(89)80029-5

K. Hashimoto, A. Kitabchi, W. Duckworth, and N. Robinson, Ultrastructure of scorbutic human skin, Acta Derm Venereol, vol.50, issue.1, pp.9-21, 1970.

D. Fossitt and T. Kowalski, Classic Skin Findings of Scurvy, Mayo Clinic Proceedings, vol.89, issue.7, p.61, 2014.
DOI : 10.1016/j.mayocp.2013.06.030

J. Patterson, Practical Skin Pathology: A Diagnostic Approach: A Volume in the Pattern Recognition Series, pp.87-88, 2013.

P. Wirth and R. Kalb, Follicular Purpuric Macules of the Extremities, Archives of Dermatology, vol.126, issue.3, pp.385-391, 1990.
DOI : 10.1001/archderm.1990.01670270117020

A. «. Randrianjohany, Déficit en vitamine C en milieu tropical : étude prospective dans l'Est réunionnais. » [En ligne]; 29 novembre 2011, Disponible sur le web

L. Simon, F. Gauvin, D. Amre, P. Saint-louis, and J. Lacroix, Serum Procalcitonin and C-Reactive Protein Levels as Markers of Bacterial Infection: A Systematic Review and Meta-analysis, Clinical Infectious Diseases, vol.39, issue.2, pp.206-223, 2004.
DOI : 10.1086/421997

«. Observatoire-régional-de-la-santé-À-la-réunion and ». L-'insuffisance-rénale-chronique-À-la-réunion, En ligne]; Novembre 2013Disponible sur le web : <http://www.orsreunion .org/IMG/file/tableaux_bord/TB_IRC_2013.pdf> 69. HAS, « Diagnostic de l'insuffisance rénale chronique » [En ligne]; Juillet 2012. D i s p o n i b l e s u r l e w e b

I. Lazareth, S. Hubert, U. Michon-pasturel, and P. Priollet, D??ficit en??vitamine C et??ulc??res de??jambe. R??sultats d'une enqu??te cas t??moins, Journal des Maladies Vasculaires, vol.32, issue.2, pp.96-105, 2007.
DOI : 10.1016/j.jmv.2007.02.003

O. Rédia-inserm, Ré Consal ? Comportements alimentaires et activité physique des réunionnais " [En ligne]; 2011, Disponible sur le web

J. Tobón, J. Whitney, and M. Jarrett, NUTRITIONAL STATUS AND WOUND SEVERITY OF OVERWEIGHT AND OBESE PATIENTS WITH VENOUS LEG ULCERS, Journal of Wound, Ostomy and Continence Nursing, vol.35, issue.Supplement, pp.43-52, 2008.
DOI : 10.1097/01.WON.0000319453.47147.53

. Inpes, Grandes tendances dans les DOM -Alcool, tabac et drogues illicites -Géographie des pratiques addictives en France » [ E n l i g n e ] ; N o v e m b r e 2 0 1 3 . D i s p o n i b l e s u r l e w e b, Analyses régionales du Baromètre santé Inpes, 2010.

C. Deligny, V. Dehlinger, V. Goëb, G. Baptiste, and S. Arfi, Paradoxical appearance of adult scurvy in Martinique, French West Indies, European Journal of Internal Medicine, vol.22, issue.2, pp.7-8, 2011.
DOI : 10.1016/j.ejim.2010.11.011

. Observatoire-régional-de-la-santé-À-la-réunion and ». Le-diabète-À-la-réunion, En ligne]; D é c e m b r e 2 0 1 3 . D i s p o n i b l e s u r l e w e b

U. Fr-;-«-comparatif-des-prix-de, V. Upsa-500mg-arôme-orange, and C. Croq-b, 2 -Upsa Conseil » [En ligne]; Aout 2014 Disponible sur le web: <http://www.unooc.fr/medicament/vitamine-c-upsa-500mg-arome-orange-cpr-croq-b2--- upsa-conseil-45164, p.61

. Femme, Poids = 61,2kg, sans emploi, valeur acide ascorbique = 4 ?mol