J. Kelley, P. Monach, J. C. Zhou, Y. Wu, J. Tanaka et al., IgA and IgG antineutrophil cytoplasmic antibody engagement of Fc receptor genetic variants influences granulomatosis with polyangiitis, Proceedings of the National Academy of Sciences, vol.108, issue.51, pp.20736-20777, 2011.
DOI : 10.1073/pnas.1109227109

H. Xiao, P. Heeringa, P. Hu, Z. Liu, M. Zhao et al., Antineutrophil cytoplasmic autoantibodies specific for myeloperoxidase cause glomerulonephritis and vasculitis in mice, Journal of Clinical Investigation, vol.110, issue.7, pp.955-63, 2002.
DOI : 10.1172/JCI0215918

M. Little, B. Ren, S. , H. Leite, M. Jr et al., Anti-Proteinase 3 Anti-Neutrophil Cytoplasm Autoantibodies Recapitulate Systemic Vasculitis in Mice with a Humanized Immune System, PLoS ONE, vol.173, issue.8426, p.28626, 2012.
DOI : 10.1371/journal.pone.0028626.t003

E. Ntatsaki, R. Watts, and D. Scott, Epidemiology of ANCA-associated Vasculitis, Rheumatic Disease Clinics of North America, vol.36, issue.3, pp.447-61, 2010.
DOI : 10.1016/j.rdc.2010.04.002

R. Deurenberg, R. Nieuwenhuis, C. Driessen, N. London, F. Stassen et al., gene among community- and hospital-acquired strains and isolates from Wegener's Granulomatosis patients, FEMS Microbiology Letters, vol.245, issue.1, pp.185-194, 2005.
DOI : 10.1016/j.femsle.2005.03.002

E. Popa and J. Tervaert, The Relation between Staphylococcus aureus and Wegener's Granulomatosis: Current Knowledge and Future Directions, Internal Medicine, vol.42, issue.9, pp.771-80, 2003.
DOI : 10.2169/internalmedicine.42.771

D. Jayne, The diagnosis of vasculitis, Best Practice & Research Clinical Rheumatology, vol.23, issue.3, 2009.
DOI : 10.1016/j.berh.2009.03.001

J. Takala, H. Kautiainen, H. Malmberg, and M. Leirisalo-­?repo, Wegener's granulomatosis in Finland in 1981???2000: clinical presentation and diagnostic delay, Scandinavian Journal of Rheumatology, vol.33, issue.6
DOI : 10.1002/art.1780370206

A. Karras, E. Guiard, C. Lévi, and E. Thervet, Granulomatosis with polyangiitis (Wegener's granulomatosis)]. Presse Médicale Paris Fr 1983, pp.1014-1037, 2012.

L. Guillevin, Eosinophilic granulomatosis with polyangiitis (Churg-­?Strauss syndrome)]. Presse Médicale Paris Fr 1983, pp.1004-1017, 2012.
URL : https://hal.archives-ouvertes.fr/hal-00873378

C. Pagnoux, P. Guilpain, and L. Guillevin, Polyangéite microscopique. Presse Médicale, pp.895-901, 2007.
DOI : 10.1016/j.lpm.2007.01.030

J. Stone, . Wegener-'s-granulomatosis-etanercept-trial-research, and . Group, Limited versus severe Wegener's granulomatosis: baseline data on patients in the Wegener's granulomatosis etanercept trial, Arthritis Rheum, vol.48, issue.8, pp.2299-309, 2003.

G. Hoffman, G. Kerr, R. Leavitt, C. Hallahan, R. Lebovics et al., Wegener Granulomatosis: An Analysis of 158 Patients, Annals of Internal Medicine, vol.116, issue.6, pp.488-98, 1992.
DOI : 10.7326/0003-4819-116-6-488

E. Reinhold-­?keller, N. Beuge, U. Latza, K. De-groot, H. Rudert et al., An interdisciplinary approach to the care of patients with Wegener's granulomatosis: Long-term outcome in 155 patients, Arthritis & Rheumatism, vol.43, issue.5, pp.1021-1053, 2000.
DOI : 10.1002/1529-0131(200005)43:5<1021::AID-ANR10>3.0.CO;2-J

E. Ballanti, D. Muzio, G. Novelli, L. Perricone, C. Perricone et al., Churg-­?Strauss syndrome with neurologic manifestations: successful treatment with intravenous immunoglobulins, Isr Med Assoc J IMAJ, vol.14, issue.9, pp.583-588, 2012.

F. Moosig and . L6, L6. Eosinophilic granulomatosis with polyangiitis: Future therapies, La Presse M??dicale, vol.42, issue.4
DOI : 10.1016/j.lpm.2013.01.006

M. Rothenberg, A. Klion, F. Roufosse, J. Kahn, P. Weller et al., Treatment of Patients with the Hypereosinophilic Syndrome with Mepolizumab, New England Journal of Medicine, vol.358, issue.12, pp.1215-1243, 2008.
DOI : 10.1056/NEJMoa070812

S. Kim, G. Marigowda, E. Oren, E. Israel, and M. Wechsler, Mepolizumab as a steroid-sparing treatment option in patients with Churg-Strauss syndrome, Journal of Allergy and Clinical Immunology, vol.125, issue.6, pp.1336-1379, 2010.
DOI : 10.1016/j.jaci.2010.03.028

F. Moosig, W. Gross, K. Herrmann, J. Bremer, and B. Hellmich, Targeting Interleukin-5 in Refractory and Relapsing Churg???Strauss Syndrome, Annals of Internal Medicine, vol.155, issue.5, pp.341-344, 2011.
DOI : 10.7326/0003-4819-155-5-201109060-00026

P. Cohen, C. Pagnoux, A. Mahr, J. Arène, L. Mouthon et al., Churg-Strauss syndrome with poor-prognosis factors: A prospective multicenter trial comparing glucocorticoids and six or twelve cyclophosphamide pulses in forty-eight patients, Arthritis & Rheumatism, vol.200, issue.4, pp.686-93, 2007.
DOI : 10.1002/art.22679

G. Majno, The ancient riddle of sigma eta psi iota sigma (sepsis), J Infect Dis, 1991.