43 3.3.1.8 ? Association clozapine avec sertindole, p.44 ,
Delayed-Onset Hypothesis of Antipsychotic Action, Archives of General Psychiatry, vol.60, issue.12, pp.1228-1263, 2003. ,
DOI : 10.1001/archpsyc.60.12.1228
Antipsychotic response in first-episode schizophrenia: efficacy of high doses and switching, European Neuropsychopharmacology, vol.23, issue.9, pp.1017-1039, 2013. ,
DOI : 10.1016/j.euroneuro.2013.04.010
Amisulpride Augmentation in Patients with Schizophrenia Partially Responsive or Unresponsive to Clozapine. A Randomized, Double-Blind, Placebo-Controlled Trial, Pharmacopsychiatry, vol.41, issue.1, pp.24-28, 2008. ,
DOI : 10.1055/s-2007-993209
Effectiveness of Rapid Initial Dose Escalation of up to Forty Milligrams per Day of Oral Olanzapine in Acute Agitation, Journal of Clinical Psychopharmacology, vol.23, issue.4, pp.342-348, 2003. ,
DOI : 10.1097/01.jcp.0000085406.08426.a8
Metformin as an adjunctive treatment to control body weight and metabolic dysfunction during olanzapine administration: A multicentric, double-blind, placebo-controlled trial, Schizophrenia Research, vol.93, issue.1-3, pp.99-108, 2007. ,
DOI : 10.1016/j.schres.2007.03.029
Does the Addition of a Second Antipsychotic Drug Improve Clozapine Treatment?, Schizophrenia Bulletin, vol.35, issue.2, pp.458-468, 2009. ,
DOI : 10.1093/schbul/sbn030
Un cas de résistance à l'insuline dans le traitement de la schizophrénie. Congrès des aliénistes, pp.346-349, 1938. ,
Pharmacological treatment strategies in the non-responsive schizophrenic patient, International Clinical Psychopharmacology, vol.11, issue.Supplement 2, pp.67-71, 1996. ,
DOI : 10.1097/00004850-199605002-00011
The Clinical Use of Plasma Clozapine Levels, Australian & New Zealand Journal of Psychiatry, vol.122, issue.4 ,
DOI : 10.3109/00048679809068332
Safety and efficacy of combined clozapine???lithium pharmacotherapy, The International Journal of Neuropsychopharmacology, vol.7, issue.1 ,
DOI : 10.1017/S1461145703003870
Mirtazapine addon therapy in the treatment of schizophrenia with atypical antipsychotics: a double-blind, randomised, placebo-controlled clinical trial, Hum. Psychopharmacol, vol.24, pp.233-238, 2009. ,
Cardiac risk at the onset of treatment in patients treated with benzodiazepines and clozapine, European Psychiatry, vol.17, issue.7, pp.419-420, 2002. ,
DOI : 10.1016/S0924-9338(02)00699-5
Definition of therapy-resistant schizophrenia and its assessment, European Psychiatry, vol.10, pp.11-18, 1995. ,
DOI : 10.1016/0767-399X(96)80079-4
Fluoxetine augmentation of clozapine treatment in patients with schizophrenia, Am. J. Psychiatry, vol.153, pp.1625-1627, 1996. ,
The 2009 Schizophrenia PORT Psychopharmacological Treatment Recommendations and Summary Statements, Schizophrenia Bulletin, vol.36, issue.1, pp.71-93, 2010. ,
DOI : 10.1093/schbul/sbp116
When Symptoms Persist: Clozapine Augmentation Strategies, Schizophrenia Bulletin, vol.27, issue.4, pp.615-628, 2001. ,
DOI : 10.1093/oxfordjournals.schbul.a006901
URL : http://schizophreniabulletin.oxfordjournals.org/cgi/content/short/27/4/615
Patient response and resource management: another view of clozapine treatment of schizophrenia ,
Hypothesis testing: Is clozapine's superior efficacy dependent on moderate D2 receptor occupancy?, Biological Psychiatry, vol.43, issue.2, pp.79-83, 1998. ,
DOI : 10.1016/S0006-3223(98)00226-1
Effectiveness of second-generation antipsychotics in patients with treatment-resistant schizophrenia: a review and meta-analysis of randomized trials, Am J Psychiatry, 2001. ,
Aripiprazole Augmentation in Clozapine-Treated Patients With Refractory Schizophrenia, The Journal of Clinical Psychiatry, vol.69, issue.5, pp.720-731, 2008. ,
DOI : 10.4088/JCP.v69n0505
Management of treatment resistance in schizophrenia, Biological Psychiatry, vol.50, issue.11 ,
DOI : 10.1016/S0006-3223(01)01271-9
Time to clozapine response in a standardized trial, Am. J. Psychiatry, vol.154, pp.1243-1247, 1997. ,
Antipsychotic Combinations vs Monotherapy in Schizophrenia: A Meta-analysis of Randomized Controlled Trials, Schizophrenia Bulletin, vol.35, issue.2, pp.443-457, 2009. ,
DOI : 10.1093/schbul/sbn018
Plasma Clozapine and Norclozapine in Patients Prescribed Different Brands of Clozapine (Clozaril, Denzapine, and Zaponex), Therapeutic Drug Monitoring, vol.32, issue.5, pp.624-627, 2010. ,
DOI : 10.1097/FTD.0b013e3181f0a1a2
Molecular pathology of schizophrenia: more than one disease process?, BMJ, vol.280, issue.6207 ,
DOI : 10.1136/bmj.280.6207.66
The treatment response scale: a retrospective method of assessing response to neuroleptics, Am J Psychiatry, vol.140, issue.9, pp.1210-1213, 1983. ,
DOSE EQUIVALENCE OF THE ANTIPSYCHOTIC DRUGS, J. Psychiatry Res, vol.11, pp.65-69, 1974. ,
DOI : 10.1016/B978-0-08-018242-1.50015-5
Dose Response and Dose Equivalence of Antipsychotics, Journal of Clinical Psychopharmacology, vol.24, issue.2, pp.192-208, 2004. ,
DOI : 10.1097/01.jcp.0000117422.05703.ae
Clozapine-related seizures, Neurology, vol.41, issue.3, pp.369-371, 1991. ,
DOI : 10.1212/WNL.41.3.369
Conventional Antipsychotic Medications for Schizophrenia, Schizophrenia Bulletin, vol.21, issue.4, 1995. ,
DOI : 10.1093/schbul/21.4.567
Pharmacotherapy of treatment-resistant schizophrenia: a clinical perspective, Evidence Based Mental Health, vol.197, issue.(Suppl 2), pp.33-37, 2014. ,
DOI : 10.1136/eb-2014-101813
Haloperidol for Acute Schizophrenic Patients, Archives of General Psychiatry, vol.37, issue.6, pp.691-695, 1980. ,
DOI : 10.1001/archpsyc.1980.01780190089011
Clozapine weight gain, plus topiramate weight loss, Can J Psychiatry, vol.45, p.198, 2000. ,
Randomized placebocontrolled study of ethyl-eicosapentaeroic acid as supplemental treatment in schizophrenia ,
Is the time course of clozapine response correlated to the time course of clozapine plasma levels? A one-year prospective study in drug-resistant patients with schizophrenia ,
Clozapine for the treatment of schizophrenia, Expert Opinion on Pharmacotherapy, vol.24, issue.18, pp.1923-1935, 2012. ,
DOI : 10.1093/schbul/23.4.663
Positron Emission Tomographic Analysis of Central D1 and D2 Dopamine Receptor Occupancy in Patients Treated With Classical Neuroleptics and Clozapine, Archives of General Psychiatry, vol.49, issue.7, pp.538-582, 1992. ,
DOI : 10.1001/archpsyc.1992.01820070032005
A Placebo-Controlled Trial of Omega-3 Fatty Acid (Ethyl Eicosapentaenoic Acid) Supplementation for Residual Symptoms and Cognitive Impairment in Schizophrenia, American Journal of Psychiatry, vol.158, issue.12, pp.2071-2074, 2001. ,
DOI : 10.1176/appi.ajp.158.12.2071
Clozapine dose in the United States and Europe: implications for therapeutic and adverse effects, J. Clin. Psychiatry, vol.55, pp.78-81, 1994. ,
Weight change on aripiprazole-clozapine combination in schizophrenic patients with weight gain and suboptimal response on clozapine: 16-week double-blind study, European Psychiatry, vol.23, issue.2, pp.114-115, 2008. ,
DOI : 10.1016/j.eurpsy.2008.01.784
Effects of adjunctive treatment with aripiprazole on body weight and clinical efficacy in schizophrenia patients treated with clozapine: a randomized, double-blind, placebo-controlled trial, The International Journal of Neuropsychopharmacology, vol.13, issue.08, pp.1115-1125, 2010. ,
DOI : 10.1017/S1461145710000490
Clozapine ? a novel antip-sychotic [letter], N Engl J ,
Risperidone augmentation for schizophrenia partially responsive to clozapine: A double-blind, placebo-controlled trial, Schizophrenia Research, vol.92, issue.1-3, pp.90-94, 2007. ,
DOI : 10.1016/j.schres.2006.12.030
Pimozide Augmentation of Clozapine Inpatients with Schizophrenia and Schizoaffective Disorder Unresponsive to Clozapine Monotherapy, Neuropsychopharmacology, vol.156, issue.6, pp.1289-1295, 2011. ,
DOI : 10.1007/BF00498834
International Consensus Study of Antipsychotic Dosing, American Journal of Psychiatry, vol.167, issue.6, pp.686-93, 2010. ,
DOI : 10.1176/appi.ajp.2009.09060802
Interaction of haloperidol plasma level and antipsychotic effect in early phases of acute psychosis treatment, Journal of Psychiatric Research, vol.44, issue.8, pp.44-487, 2010. ,
DOI : 10.1016/j.jpsychires.2009.11.004
Antipsychotic drug mechanisms: links between therapeutic effects, metabolic side effects and the insulin signaling pathway, Molecular Psychiatry, vol.111, issue.10, pp.918-947, 2008. ,
DOI : 10.1124/mol.66.1.97
A placebo-controlled crossover trial of d-cycloserine added to clozapine in patients with schizophrenia, Biological Psychiatry, vol.45, issue.4, pp.45-512, 1999. ,
DOI : 10.1016/S0006-3223(98)00367-9
A Placebo-Controlled Pilot Study of the Ampakine CX516 Added to Clozapine in Schizophrenia, Journal of Clinical Psychopharmacology, vol.21, issue.5 ,
DOI : 10.1097/00004714-200110000-00005
Lamotrigine as add-on therapy in schizophrenia: results of 2 placebo-controlled trials, J. Clin. Psychopharmacol, vol.27, pp.582-589, 2007. ,
Strategies for Improving Treatment Adherence in Schizophrenia and Schizoaffective Disorder, The Journal of Clinical Psychiatry, vol.71, issue.suppl 2, pp.20-26, 2010. ,
DOI : 10.4088/JCP.9096su1cc.04
The 'atypicality' of antipsychotics: a concept re-examined and re-defined, Nature Reviews Drug Discovery, vol.165, issue.3, pp.197-202, 2009. ,
DOI : 10.1038/nrd2806
Clozapine and Metabolite Concentrations during Treatment of Patients with Chronic Schizophrenia, The Journal of Clinical Pharmacology, vol.147, issue.Suppl., pp.721-728, 1999. ,
DOI : 10.1177/00912709922008245
Olanzapine Augmentation of Clozapine, Annals of Clinical Psychiatry, vol.10, issue.3 ,
DOI : 10.3109/10401239809148944
Patterns of clozapine prescribing in a mental health service in New Zealand, Pharmacy World & Science, vol.21, issue.4, pp.503-514, 2010. ,
DOI : 10.1007/s11096-010-9398-5
World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Schizophrenia, Part 1: Update 2012 on the acute treatment of schizophrenia and the management of treatment resistance, The World Journal of Biological Psychiatry, vol.22, issue.1 ,
DOI : 10.1016/j.schres.2007.02.009
AGNP Consensus Guidelines for Therapeutic Drug Monitoring in Psychiatry: Update 2011, Pharmacopsychiatry, vol.44, issue.06, pp.195-235, 2011. ,
DOI : 10.1055/s-0031-1286287
A historical perspective of clozapine, J Clin Psychiatry, vol.6012, 1999. ,
Clozapine Alone versus Clozapine and Risperidone with Refractory Schizophrenia, New England Journal of Medicine, vol.354, issue.5, pp.472-482, 2006. ,
DOI : 10.1056/NEJMoa053222
Adherence to treatment guidelines in clinical practice: study of antipsychotic treatment prior to clozapine initiation, The British Journal of Psychiatry, vol.201, issue.6, 2012. ,
DOI : 10.1192/bjp.bp.111.105833
Clozapine Augmented With Risperidone in the Treatment of Schizophrenia: A Randomized, Double-Blind, Placebo-Controlled Trial, American Journal of Psychiatry, vol.162, issue.1, pp.130-136, 2005. ,
DOI : 10.1176/appi.ajp.162.1.130
Clozapine for the Treatment-Resistant Schizophrenic, Archives of General Psychiatry, vol.45, issue.9, pp.789-796, 1988. ,
DOI : 10.1001/archpsyc.1988.01800330013001
Psychopharmacologic treatment of schizophrenia Does fast dissociation from the dopamine D(2) receptor explain the action of atypical antipsychotics? A new hypothesis, Schizophr Bull Am J Psychiatry, vol.19158, pp.287-302, 1993. ,
Evidence for Onset of Antipsychotic Effects Within the First 24 Hours of Treatment, American Journal of Psychiatry, vol.162, issue.5, pp.939-985, 2005. ,
DOI : 10.1176/appi.ajp.162.5.939
Adjunct Divalproex or Lithium to Clozapine in Treatment-Resistant Schizophrenia, Psychiatric Quarterly, vol.152, issue.2, pp.81-95, 2006. ,
DOI : 10.1007/s11126-006-7963-9
Examining Concentration-Dependent Toxicity of Clozapine: Role of Therapeutic Drug Monitoring, Journal of Psychiatric Practice, vol.11, issue.5, pp.289-301, 2005. ,
DOI : 10.1097/00131746-200509000-00003
Influence of neuroleptic dose and class in treatment-resistant schizophrenia relapse, Presented at the 32nd Annual Meeting of the New Clinical Drug Evaluation Unit, 1992. ,
Treatment of neuroleptic resistant schizophrenia relapse ,
Standard and Higher Dose of Olanzapine in Patients With Schizophrenia or Schizoaffective Disorder, Journal of Clinical Psychopharmacology, vol.28, issue.4, pp.392-400, 2008. ,
DOI : 10.1097/JCP.0b013e31817e63a5
Randomized controlled augmentation trials in clozapine-resistant schizophrenic patients: a critical review, European Psychiatry, vol.20, issue.5-6 ,
DOI : 10.1016/j.eurpsy.2004.12.007
Minimal Dose for Severe Poisoning and Influencing Factors in Acute Human Clozapine Intoxication, Clinical Neuropharmacology, vol.33, issue.5, pp.230-234, 2010. ,
DOI : 10.1097/WNF.0b013e3181f0ec55
Placebocontrolled trial of lamotrigine added to conventional and atypical antipsychotics in schizophrenia, Biol. Psychiatry, pp.56-441, 2004. ,
Plasma clozapine levels and clinical response for treatment-refractory schizophrenic patients, Am. J. Psychiatry, vol.152, pp.179-182, 1995. ,
Branded versus generic clozapine: bioavailability comparison and interchangeability issues, J Clin Psychiatry, vol.5, pp.18-22, 2001. ,
A randomized, placebo-controlled clinical trial of combined citalopram and clozapine in the treatment of negative symptoms of schizophrenia, Chin Ment Health J, vol.20, pp.696-698, 2006. ,
Practice guideline for the treatment of patients with schizophrenia, second edition, Am J Psychiatry, vol.161, issue.2, pp.1-56, 2004. ,
Early Prediction of Antipsychotic Nonresponse Among Patients With Schizophrenia, The Journal of Clinical Psychiatry, vol.68, issue.03, pp.352-60, 2007. ,
DOI : 10.4088/JCP.v68n0301
Clinical effects of clozapine in chronic schizophrenia: response to treatment and predictors of outcome, Am. J. Psychiatry, vol.151, pp.1744-1752, 1994. ,
Limites d'efficacité des chimiothérapies ,
Impact of Tobacco Smoking Cessation on Stable Clozapine or Olanzapine Treatment, Annals of Pharmacotherapy, vol.44, issue.4, pp.727-759, 2010. ,
DOI : 10.1345/aph.1M398
Fluvoxamine Reduces the Clozapine Dosage Needed in Refractory Schizophrenic Patients, The Journal of Clinical Psychiatry, vol.61, issue.8, pp.61-594, 2000. ,
DOI : 10.4088/JCP.v61n0809
Adjunctive Fluvoxamine Inhibits Clozapine-Related Weight Gain and Metabolic Disturbances, The Journal of Clinical Psychiatry, vol.65, issue.6, pp.65-766, 2004. ,
DOI : 10.4088/JCP.v65n0607
5-HT2, and 5-HT1A Receptor Occupancy in Patients With Schizophrenia: a Triple Tracer PET Study, Am J Psychiatry, vol.164, pp.1411-1417, 2007. ,
The side-effects of clozapine: A four year follow-up study, Progress in Neuro-Psychopharmacology and Biological Psychiatry, vol.18, issue.3, pp.537-544, 1994. ,
DOI : 10.1016/0278-5846(94)90010-8
Comparative study of clozapine, electroshock and the combination of ECT with clozapine in treatment-resistant schizophrenic patients. Pak, J. Biol ,
A systematic approach to treatment resistance in schizophrenic disorders, Treatment Resistance in Schizophrenia. Braunschweig, pp.22-25, 1988. ,
Effectiveness of Clozapine Versus Olanzapine, Quetiapine, and Risperidone in Patients With Chronic Schizophrenia Who Did Not Respond to Prior Atypical Antipsychotic Treatment, American Journal of Psychiatry, vol.163, issue.4, pp.600-610, 2006. ,
DOI : 10.1176/ajp.2006.163.4.600
Antipsychotic and anticholinergic effects on two types of spatial memory in schizophrenia, Schizophrenia Research, vol.68, issue.2-3, pp.225-233, 2004. ,
DOI : 10.1016/S0920-9964(03)00123-3
A prospective study of clozapine in treatment-resistant schizophrenic patients, Psychopharmacology, vol.10, issue.S1 ,
DOI : 10.1007/BF00442563
Effects of Six Months of Clozapine Treatment on the Quality of Life of Chronic Schizophrenic Patients, Psychiatric Services, vol.41, issue.8, pp.41-892, 1990. ,
DOI : 10.1176/ps.41.8.892
Serotonin receptors : their key role in drugs to treat schizophrenia, Progress in Neuro-Psychopharmacology and Biological Psychiatry, vol.27, issue.7, pp.1159-72, 2003. ,
DOI : 10.1016/j.pnpbp.2003.09.010
Case reports of the reemergence of psychotic symptoms after conversion from brand-name clozapine to a generic formulation, Clinical Therapeutics, vol.23, issue.10, pp.1720-1731, 2001. ,
DOI : 10.1016/S0149-2918(01)80139-9
The Texas Medication Algorithm Project antipsychotic algorithm for schizophrenia: 2006 update, J Clin Psychiatry, vol.68, issue.11, pp.1751-62, 2007. ,
P.3.c.037 Haloperidol in combination with clozapine in treatment-refractory patients with schizophrenia, European Neuropsychopharmacology, vol.16, p.416, 2006. ,
DOI : 10.1016/S0924-977X(06)70524-7
Amisulpride augmentation of clozapine: an open non-randomized study in patients with schizophrenia partially responsive to clozapine, Acta Psychiatrica Scandinavica, vol.173, issue.44 ,
DOI : 10.1001/archpsyc.60.6.553
Effect of aripiprazole augmentation of clozapine in schizophrenia: A double-blind, placebo-controlled study, Schizophrenia Research, vol.127, issue.1-3, pp.93-99, 2011. ,
DOI : 10.1016/j.schres.2010.12.011
Topiramate augmentation of clozapine in schizophrenia: a double-blind, placebo-controlled study Clinical management of clozapine patients in relation to efficacy and side-effects, J Psychopharmacol Br J Psychiatry, vol.17, issue.2, pp.54-63, 1992. ,
Neurochemical Mechanisms of Action of ECS, The Journal of ECT, vol.14, issue.3, pp.153-171, 1998. ,
DOI : 10.1097/00124509-199809000-00002
Antipsychotics Associated with the Development of Type 2 Diabetes in Antipsychotic-Na??ve Schizophrenia Patients, Neuropsychopharmacology, vol.156, issue.9, pp.1997-2004, 2010. ,
DOI : 10.1002/pds.1781
Optimizing clozapine treatment, Acta Psychiatrica Scandinavica, vol.163, issue.Suppl, pp.411-422, 2011. ,
DOI : 10.1111/j.1600-0447.2011.01710.x
Augmenting Clozapine With Sertindole, Journal of Clinical Psychopharmacology, vol.32, issue.2 ,
DOI : 10.1097/JCP.0b013e318248dfb8
Generic clozapine: outcomes after switching formulations, The British Journal of Psychiatry, vol.189, issue.2, pp.184-185, 2006. ,
DOI : 10.1192/bjp.bp.105.017079
Augmentation With a Second Antipsychotic in Patients With Schizophrenia Who Partially Respond to Clozapine, Journal of Clinical Psychopharmacology, vol.27, issue.2, pp.198-204, 2007. ,
DOI : 10.1097/JCP.0b013e318036bfbb
Clozapine treatment in Denmark: concomitant psychotropic medication and hematologic monitoring in a system with liberal usage practices, J Clin Psychiatry, vol.55, pp.44-53, 1994. ,
A dose-ranging exploratory study of the effects of ethyl-eicosapentaenoate in patients with persistent schizophrenic symptoms, Journal of Psychiatric Research, vol.36, issue.1, pp.7-18, 2002. ,
DOI : 10.1016/S0022-3956(01)00048-6
Clozapine and norclozapine plasma concentrations and clinical response of treatment-refractory schizophrenic patients, Am. J ,
Clozapine, single photon emission tomography, and the D2 dopamine receptor blockade hypothesis of schizophrenia, The Lancet, vol.340, issue.8813, pp.199-202, 1992. ,
DOI : 10.1016/0140-6736(92)90467-H
Plasma clozapine concentrations predict clinical response in treatment-resistant schizophrenia, J. Clin. Psychiatry, vol.55, pp.133-136, 1994. ,
Clozapine in China: a review and preview of US/PRC collaboration, Psychopharmacology, vol.10, issue.S1, pp.87-91, 1989. ,
DOI : 10.1007/BF00442568
Clozapine resistance: Augmentation strategies, European Neuropsychopharmacology, vol.22, issue.3, pp.165-82, 2009. ,
DOI : 10.1016/j.euroneuro.2011.08.005
Is clonidine useful for treatment of clozapine-induced sialorrhea?, Journal of Psychopharmacology, vol.269, issue.4, pp.426-428, 2005. ,
DOI : 10.1177/0269881105053311
Atypical Antipsychotics: Pharmacokinetics, Therapeutic Drug Monitoring and Pharmacological Interactions, Current Medicinal Chemistry, vol.11, issue.3, pp.279-296, 2004. ,
DOI : 10.2174/0929867043456089
Augmentation of clozapine partial responders with conventional antipsychotics, Schizophrenia Research, vol.60, issue.1, pp.97-98, 2003. ,
DOI : 10.1016/S0920-9964(02)00293-1
Clozapine-induced EEG abnormalities and clinical response to clozapine, J Neuropsychiatry Clin Neurosci, vol.7, pp.466-470, 1995. ,
Head-to-head comparisons of metabolic side effects of second generation antipsychotics in the treatment of schizophrenia: a systematic review and metaanalysis, Schizophrenia Research, vol.123, pp.225-233, 2010. ,
What is an Adequate Trial with Clozapine?, Clinical Pharmacokinetics, vol.171, issue.4, pp.607-618, 2003. ,
DOI : 10.2165/00003088-200342070-00001
Sulpiride augmentation in people with schizophrenia partially responsive to clozapine. A double-blind, placebo-controlled study, The British Journal of Psychiatry, vol.171, issue.6, pp.569-573, 1997. ,
DOI : 10.1192/bjp.171.6.569
Fluvoxamine augmentation in clozapine-resistant schizophrenia: an open pilot study, Biological Psychiatry, vol.40, issue.7, pp.671-674, 1996. ,
DOI : 10.1016/0006-3223(96)00170-9
Tolerability and Efficacy of Clozapine Combined with Lithium in Schizophrenia and Schizoaffective Disorder, Journal of Clinical Psychopharmacology, vol.23, issue.3 ,
DOI : 10.1097/01.jcp.0000084026.22282.5f
Risperidone as adjunctive therapy in clozapine treatment of refractory schizophrenia: a meta-analysis of randomized, placebo-controlled trial ,
Pharmacological Augmentation Strategies for Schizophrenia Patients With Insufficient Response to Clozapine: A Quantitative Literature Review, Schizophrenia Bulletin, vol.38, issue.5, 2011. ,
DOI : 10.1093/schbul/sbr004
Effect of fluoxetine on the plasma concentrations of clozapine and its major metabolites in patients with schizophrenia, International Clinical Psychopharmacology, vol.13, issue.3, pp.141-145, 1998. ,
DOI : 10.1097/00004850-199805000-00009
Antipsychotic drug action: targets for drug discovery with neurochemical imaging, Expert Review of Neurotherapeutics, vol.6, issue.1, pp.57-64, 2006. ,
DOI : 10.1586/14737175.6.1.57
Augmentation of Aripiprazole with Low-Dose Clozapine, Pharmacotherapy, vol.60, issue.3, pp.1599-1602, 2007. ,
DOI : 10.2174/0929867043456034
How effective is it to sequentially switch among Olanzapine, Quetiapine and Risperidone????A randomized, open-label study of algorithm-based antipsychotic treatment to patients with symptomatic schizophrenia in the real-world clinical setting, Psychopharmacology, vol.67, issue.7273, 2007. ,
DOI : 10.1007/s00213-007-0872-2
Treatment resistant schizophrenia and response to antipsychotics: A review, Schizophrenia Research, vol.133, issue.1-3, pp.54-62, 2011. ,
DOI : 10.1016/j.schres.2011.09.016
Prior Antipsychotic Prescribing in Patients Currently Receiving Clozapine, The Journal of Clinical Psychiatry, vol.64, issue.1, pp.30-34, 2003. ,
DOI : 10.4088/JCP.v64n0107
Augmentation of clozapine with a second antipsychotic - a meta-analysis of randomized, placebo-controlled studies, Acta Psychiatrica Scandinavica, vol.43, issue.suppl. 4, pp.419-425, 2009. ,
DOI : 10.1111/j.1600-0447.2009.01367.x
Augmentation of clozapine with a second antipsychotic - a meta-analysis, Acta Psychiatrica Scandinavica, vol.35, issue.Suppl 1, pp.15-24 ,
DOI : 10.1111/j.1600-0447.2011.01792.x
Switching to Olanzapine After Unsuccessful Treatment With Risperidone During the First Episode of Schizophrenia, The Journal of Clinical Psychiatry, vol.67, issue.10, pp.1067-72, 2006. ,
DOI : 10.4088/JCP.v67n1013
Lamotrigine in treatment-resistant schizophrenia: a randomized placebo-controlled crossover trial, Biol. Psychiatry, vol.54, pp.1241-1248, 2003. ,
Topiramate add-on in treatment-resistant schizophrenia: a randomized, double-blind, placebo-controlled, crossover trial, J. Clin ,
Therapeutic effect of clozapine at an unusually high plasma level, Am J Psychiatry, vol.153, pp.133-134, 1996. ,
Adjunctive Risperidone for Partially Responsive People with Schizophrenia Treated with Clozapine, Neuropsychopharmacology, vol.212, issue.11, pp.2274-2283, 2010. ,
DOI : 10.1038/npp.2010.101
Toxic Delirium with Low-Dose Clozapine, The Canadian Journal of Psychiatry, vol.153, issue.4, pp.429-430, 1997. ,
DOI : 10.1177/070674379704200418
Clozapine-resistant schizophrenia: a positive approach, The British Journal of Psychiatry, vol.181, issue.3, pp.181-184, 2002. ,
DOI : 10.1192/bjp.181.3.184
A Double-Blind Controlled Study of Adjunctive Treatment With Risperidone in Schizophrenic Patients Partially Responsive to Clozapine, The Journal of Clinical Psychiatry, vol.66, issue.01, pp.63-72, 2005. ,
DOI : 10.4088/JCP.v66n0109
The effect of lamotrigine augmentation of clozapine in a sample of treatment-resistant schizophrenic patients: A double-blind, placebo-controlled study, Schizophrenia Research, vol.93, issue.1-3, pp.93-109, 2007. ,
DOI : 10.1016/j.schres.2007.02.009