Instability of repetitive DNA sequences: The role of replication in multiple mechanisms, Proceedings of the National Academy of Sciences, pp.98-8319, 2001. ,
DOI : 10.1073/pnas.111008398
Glow in the Dark: Fluorescent Proteins as Cell and Tissue-Specific Markers in Plants, Molecular Plant, vol.4, issue.5, pp.794-804, 2011. ,
DOI : 10.1093/mp/ssr059
Thrombin signalling and protease-activated receptors, Nature, vol.407, issue.6801, pp.258-264, 2000. ,
DOI : 10.1038/35025229
Protective effects of C5a blockade in sepsis, Nature medicine, vol.5, issue.7, pp.788-792, 1999. ,
A Novel Extracellular Matrix Protein from Tomato Associated with Lignified Secondary Cell Walls, THE PLANT CELL ONLINE, vol.6, issue.8, pp.1035-1047, 1994. ,
DOI : 10.1105/tpc.6.8.1035
Identification of a novel peptide motif that mediates cross-linking of proteins to cell walls, The Plant Journal, vol.90, issue.5, pp.563-570, 1999. ,
DOI : 10.1016/0168-9452(88)90065-9
Characterization of proteins from sunflower leaves and seeds: relationship of biomass and seed yield. Trends in new crops and new uses, pp.143-149, 2002. ,
A High-Affinity Fully Human Anti-IL-6 mAb, 1339, for the Treatment of Multiple Myeloma, Clinical Cancer Research, vol.15, issue.23, pp.15-7144, 2009. ,
DOI : 10.1158/1078-0432.CCR-09-1483
Visualizing mRNA Expression in Plant Protoplasts: Factors Influencing Efficient mRNA Uptake and Translation, THE PLANT CELL ONLINE, vol.1, issue.3, pp.301-311, 1989. ,
DOI : 10.1105/tpc.1.3.301
Removal of a cryptic intron and subcellular localization of green fluorescent protein are required to mark transgenic Arabidopsis plants brightly, Proceedings of the National Academy of Sciences, vol.94, issue.6, pp.94-2122, 1997. ,
DOI : 10.1073/pnas.94.6.2122
Use of Ubiquitin Fusions to Augment Protein Expression in Transgenic Plants, Plant Physiology, vol.119, issue.2, pp.713-724, 1999. ,
DOI : 10.1104/pp.119.2.713
Monoclonal antibody manufacturing in transgenic plants ??? myths and realities, Current Opinion in Biotechnology, vol.13, issue.6, pp.630-635, 2002. ,
DOI : 10.1016/S0958-1669(02)00351-8
Green fluorescent protein as a vital marker for nondestructive detection of transformation events in transgenic plants. Plant cell, tissue and organ culture, pp.303-318, 2006. ,
Tracking of the CaMV-35S promoter performance in GFP transgenic tobacco, with a special emphasis on flowers and reproductive organs, confirmed its predominant activity in vascular tissues, Plant Cell, Tissue and Organ Culture, vol.11, issue.3, pp.94-239, 2008. ,
DOI : 10.1007/s11240-007-9312-6
Bioprospecting in plants for engineered proteins, Current Opinion in Plant Biology, vol.8, issue.2, pp.223-226, 2005. ,
DOI : 10.1016/j.pbi.2005.01.003
STABILITY OF INTERLEUKIN 6, SOLUBLE INTERLEUKIN 6 RECEPTOR, INTERLEUKIN 10 AND CC16 IN HUMAN SERUM, Cytokine, vol.19, issue.5, pp.228-235, 2002. ,
DOI : 10.1016/S1043-4666(02)91961-7
TOBACCO AS A POTENTIAL FOOD SOURCE AND SMOKE MATERIAL: NUTRITIONAL EVALUATION OF TOBACCO LEAF PROTEIN, Journal of Food Science, vol.4, issue.2, pp.320-327, 1980. ,
DOI : 10.1111/j.1365-2621.1980.tb02605.x
Major chromosomal rearrangements induced by T-DNA transformation in Arabidopsis, Genetics, vol.149, issue.2, pp.641-650, 1998. ,
Recombinant production of the human complement factor 5 a in Escherichia coli, African Journal of Biotechnology, issue.81, pp.11-14685, 2012. ,
High-Level Transient Expression of ER-Targeted Human Interleukin 6 in Nicotiana benthamiana, PLoS ONE, vol.27, issue.11, p.48938, 2012. ,
DOI : 10.1371/journal.pone.0048938.t004
Expression and Subcellular Targeting of Human Complement Factor C5a in Nicotiana species, PLoS ONE, vol.30, issue.12, p.53023, 2012. ,
DOI : 10.1371/journal.pone.0053023.s003
Recombinant Production of Human Interleukin 6 in Escherichia coli, PLoS ONE, vol.11, issue.1, p.54933, 2013. ,
DOI : 10.1371/journal.pone.0054933.t003
Activity of a chimeric promoter with the doubled CaMV 35S enhancer element in protoplast-derived cells and transgenic plants in maize, Plant Molecular Biology, vol.3, issue.3, pp.415-428, 1993. ,
DOI : 10.1007/BF00028800
Fluorescent protein spectra, Journal of Cell Science, vol.114, issue.5, pp.837-838, 2001. ,
A protocol for the fluorometric quantification of mGFP5-ER and sGFP (S65T) in transgenic plants, Plant Molecular Biology Reporter, vol.17, issue.4, pp.385-395, 1999. ,
DOI : 10.1023/A:1007654318401
Protective Effects of IL-6 Blockade in Sepsis Are Linked to Reduced C5a Receptor Expression, The Journal of Immunology, vol.170, issue.1, pp.503-507, 2003. ,
DOI : 10.4049/jimmunol.170.1.503
Antibodies and Genetically Engineered Related Molecules: Production and Purification, Biotechnology Progress, vol.20, issue.3, pp.639-654, 2004. ,
DOI : 10.1021/bp030070k
Enhanced expression in tobacco of the gene encoding green fluorescent protein by modification of its codon usage, Plant molecular biology, issue.6, pp.33-989, 1997. ,
Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein, Nature Biotechnology, vol.177, issue.12, pp.22-1567, 2004. ,
DOI : 10.1016/S0165-0270(00)00354-X
Key issues in the purification and characterization of recombinant proteins for therapeutic use, Advanced Drug Delivery Reviews, vol.4, issue.2, pp.87-111, 1989. ,
DOI : 10.1016/0169-409X(89)90015-X
Structure and Function of Plant Cell Wall Proteins, THE PLANT CELL ONLINE, vol.5, issue.1, p.9, 1993. ,
DOI : 10.1105/tpc.5.1.9
S. 1.9 A crystal structure of interleukin 6: implications for a novel mode of receptor dimerization and signaling, pp.989-997, 1997. ,
Study of tobacco plant as a possible nutritive protein source, Acta Alimentaria, vol.39, issue.2, pp.149-156, 2010. ,
DOI : 10.1556/AAlim.39.2010.2.6
Genetic approaches for studying transgene inheritance and genetic recombination in three successive generations of transformed tobacco, Genetics and Molecular Biology, vol.35, issue.3, pp.640-649, 2012. ,
DOI : 10.1590/S1415-47572012000400015
Tobacco, a highly efficient green bioreactor for production of therapeutic proteins, Biotechnology Advances, vol.28, issue.2, pp.214-221, 2010. ,
DOI : 10.1016/j.biotechadv.2009.11.008
Molecular farming in plants: host systems and expression technology, Trends in Biotechnology, vol.21, issue.12, pp.570-578, 2003. ,
DOI : 10.1016/j.tibtech.2003.10.002
Instability, stabilization, and formulation of liquid protein pharmaceuticals, International Journal of Pharmaceutics, vol.185, issue.2, pp.129-188, 1999. ,
DOI : 10.1016/S0378-5173(99)00152-0