E. Jacqz-aigrain, -Transfert placentaire des médicaments et risques foetaux- Médecine thérapeutique, Pédiatrie ?, vol.1, issue.4, pp.372-77, 1998.
URL : https://hal.archives-ouvertes.fr/hal-00744538

W. J. Larsen, Embryologie humaine-Edition De, 2011.

D. Ronald and W. , -Embryologie-Réussir le PCEM1-Edition Pradel, 2002.
URL : https://hal.archives-ouvertes.fr/hal-00557775

S. Horton, A. Tuerk, and D. Cook, Maximum recommended dosage of lithium for pregnant women based on a PBPK model for lithium absorption-Advances in bioinformatics, 2012.

F. Bavoux, Entretiens de Bichat-28 septembre 2011-disponible à l'adresse : medscape.fr-consulté le 12, 2013.

D. Newport, A. C. Jeffrey, . Viguera, and A. J. Beach, Lithium placental passage and obstetrical outcome: implications for clinical management during late pregnancy- American journal of psychiatry, pp.162-2162, 2005.

S. Yacobi and A. Et-ornoy, -Is lithium a real teratogen? What can we conclude from the prospective versus retrospective studies? A review -The Israel journal of psychiatry and related sciences, pp.45-95, 2008.
URL : https://hal.archives-ouvertes.fr/jpa-00244467

S. Dallay, Dallay-Prise en charge du trouble bipolaire chez la femme enceinte en âge de procréer-L'information psychiatrique, 2008.

J. Nicolai, S. H. Vles, and A. P. Et-aldenkamp, -Neurodevelopmental delay in children exposed to antiepileptic drugs in utero: a critical review directed at structural studybias-Journal of the neurological sciences-271 (1,2) -Août, pp.1-14, 2008.
URL : https://hal.archives-ouvertes.fr/hal-00358311

C. Cummings, M. Stewart, and M. Stevenson, Neurodevelopment of children exposed in utero to lamotrigine, sodium valproate and carbamazepine-Archives of disease in childhood, pp.96-103

K. J. Meador and D. W. Et-loring, -Risks of in utero exposure to valproate-JAMA : The Journal of the American Medical Association -309, pp.1730-1731, 2013.
URL : https://hal.archives-ouvertes.fr/insu-01438807

P. B. Pennell, A. M. Klein, and N. Browning, Differential effects of antiepileptic drugs on neonatal outcomes-Epilepsy and Behavior -24 (4)-Août 2012, pp.449-456

J. Jentink, M. A. Loane, and H. Dolk, Valproic Acid Monotherapy in Pregnancy and Major Congenital Malformations, New England Journal of Medicine, vol.362, issue.23, pp.362-2185, 2010.
DOI : 10.1056/NEJMoa0907328

B. M. Kluger and K. J. Et-meador, -Teratogenicity of antiepileptic medications-Seminars in neurology, Juillet, vol.28, issue.3, pp.328-363, 2008.
URL : https://hal.archives-ouvertes.fr/hal-01502135

K. J. Meador, G. A. Baker, and R. H. Finnell, In utero antiepileptic drug exposure: Fetal death and malformations, Utero antiepileptic drug exposure: fetal death and malformations, pp.407-412, 2006.
DOI : 10.1212/01.wnl.0000227919.81208.b2

G. Koren, A. A. Nava-ocampo, and M. E. Moretti, Major malformations with valproic acid-Canadian family physician -52, pp.441-447, 2006.

J. A. Morrow, E. Russell, and L. Guthrie, Malformation risks of antiepileptic drugs in pregnancy: a prospective study from the UK Epilepsy and Pregnancy Register, Journal of Neurology, Neurosurgery & Psychiatry, vol.77, issue.2, pp.77-193, 2006.
DOI : 10.1136/jnnp.2005.074203

E. Campbell, E. Devenney, and J. Morrow, Recurrence risk of congenital malformations in infants exposed to antiepileptic drugs in utero-Epilepsia -54 (1)- Janvier 2013, pp.165-171

E. Mawhinney, J. Campbell, and J. Craig, Valproate and the risk for congenital malformations: Is formulation and dosage regime important?-Seizure: european journal of epilepsy, pp.21-215, 2012.

S. Duncan, Teratogenesis of sodium valproate-Current opinion in neurology, pp.175-180, 2007.

C. Stodgell, J. Ingram, and M. O-'bara, Induction of the homeotic gene Hoxa1 through valproic acid's teratogenic mechanism of action-Neurotoxicology and Teratology -28 (5)-Octobre, pp.617-624, 2006.

J. Jentink, M. K. Bakker, and C. Nijenhuis, Does folic acid use decrease the risk for spina bifida after in utero exposure to valproic acid?-Pharmacoepidemiology and drug safety -19 (8)-Août, pp.803-807, 2010.

C. Nadebaum, V. Anderson, and F. Vajda, The Australian Brain and Cognition and Antiepileptic Drugs Study: IQ in School-Aged Children Exposed to Sodium Valproate and Polytherapy, Journal of the International Neuropsychological Society, vol.51, issue.01, pp.17-133, 2011.
DOI : 10.1038/nrd3076

K. J. Meador, G. A. Baker, and N. Browning, Fetal antiepileptic drug exposure and cognitive outcomes at age 6 years (NEAD study): a prospective observational study- Lancet Neurology -12 (3) -Mars 2013, pp.244-52

K. J. Meador, G. A. Baker, and N. Browning, Effects of fetal antiepileptic drug exposure: Outcomes at age 4.5 years, Neurology, vol.78, issue.16, pp.1207-1214, 2012.
DOI : 10.1212/WNL.0b013e318250d824

M. J. Cohen, K. J. Meador, and N. Browning, Fetal antiepileptic drug exposure: motor, adaptive and emotional/behavioral functioning at age 3 years-Epilepsy and Behavior, pp.240-246, 2011.

C. Frisch, K. Hüsch, and F. Angenstein, Dose dependent memory effects and cerebral volume changes after in utero exposure to valproate in the rat-Epilepsia, pp.1432-1441, 2009.

M. J. Cohen, K. J. Meador, and N. Browning, Fetal antiepileptic drug exposure: adaptive and emotional/behavioral Functioning at age 6 years-Epilepsy and Behavior-Septembre, 2013.

K. Eriksson, K. Viinikainen, and A. Mönkkönen, Children exposed to valproate in utero, population based evaluation of risks and confounding factors for long-term neurocognitive development-Epilepsy research, pp.65-189, 2005.

A. Bravo, D. Hernandez, and L. Martinez-villarreal, Severe consequences of carbamazepine exposure in utero-BMJ case reports, 2011.

J. Jentink, H. Dolk, and M. A. Loane, Intrauterine exposure to carbamazepine and specific congenital malformations: systematic review and case-control study, BMJ, vol.341, issue.dec02 1, pp.341-2010
DOI : 10.1136/bmj.c6581

L. B. Holmes, B. A. Coull, and J. Dorfman, The correlation of deficits in IQ with midface and digit hypoplasia in children exposed in utero to anticonvulsant drugs- The journal of pediatrics, pp.146-118, 2005.

K. Wide, B. Winbladh, and B. Et-källén, Major malformations in infants exposed to antiepileptic drugs in utero, with emphasis on carbamazepine and valproic acid: a nation-wide, population-based register study, Acta Paediatrica, vol.8, issue.Suppl 5, pp.1992-93174, 2004.
DOI : 10.1111/j.1651-2227.2004.tb00701.x

W. F. Rayburn, C. L. Gonzalez, and K. M. Parker, Chronic prenatal exposure to carbamazepine and behavior effects on mice offspring-American journal of obstetrics and gynecology, pp.517-521, 2004.

E. Gaily, E. Kantola-sorsa, and V. Hiilesmaa, Normal intelligence in children with prenatal exposure to carbamazepine, Neurology, vol.62, issue.1, pp.28-32, 2004.
DOI : 10.1212/WNL.62.1.28

A. Sabers and T. Et-tomson, Managing antiepileptic drugs during pregnancy and lactation-Current opinion in neurology, pp.157-161, 2009.

M. C. Cunnington, J. G. Weil, and J. A. Messenheimer, Final results from 18 years of the International Lamotrigine Pregnancy Registry, Neurology, vol.76, issue.21, pp.1817-1823, 2011.
DOI : 10.1212/WNL.0b013e31821ccd18

F. J. Vajda, J. E. Graham, and A. A. Hitchcock, Is lamotrigine a significant human teratogen? Observations from the Australian Pregnancy Register, Seizure, vol.19, issue.9, pp.558-561, 2010.
DOI : 10.1016/j.seizure.2010.07.019

L. B. Holmes and S. Et-hernandez-diaz, -Newer anticonvulsivants: lamotrigine, topiramate, and gabapentine, clinical and molecular teratology-part. A-Août, 2012.
URL : https://hal.archives-ouvertes.fr/hal-00956948

S. Sarit, G. Koren, and N. , I-Teratogenicity of lamotrigine-Canadian Family Physician-53 (6)-Juin, pp.1007-1009, 2007.

S. Hunt, J. Craig, and J. Et-morrow, INCREASED FREQUENCY OF ISOLATED CLEFT PALATE IN INFANTS EXPOSED TO LAMOTRIGINE DURING PREGNANCY, Neurology, vol.72, issue.12, pp.1108-1109, 2009.
DOI : 10.1212/01.wnl.0000346463.44116.56

. H. Dolk, J. Jentink, and M. Loane, Does lamotrigine use in pregnancy increase orofacial cleft risk relative to other malformations? -Neurology -71 (10) -Septembre, pp.714-722, 2008.

M. Cunnington, S. Ferber, and G. Quartey, Effect of dose on the frequency of major birth defects following fetal exposure to lamotrigine monotherapy in an international observational study -Epilepsia -48 (6)-2007, pp.1207-1210

D. J. Newport, Z. Stowe, and A. C. Viguera, Lamotrigine in bipolar disorder: efficacy during pregnancy-Bipolar disorders, pp.432-436, 2008.

C. Cummings, M. Stewart, and M. Stevenson, Neurodevelopment of children exposed in utero to lamotrigine, sodium valproate and carbamazepine-Archives of disease in childhood, Juillet, vol.2011, issue.7, pp.96-643

J. Manent, I. Jorquera, and V. Franco, Antiepileptic drugs and brain maturation: Fetal exposure to lamotrigine generates cortical malformations in rats, Epilepsy Research, vol.78, issue.2-3, pp.2-3, 2008.
DOI : 10.1016/j.eplepsyres.2007.10.014

URL : https://hal.archives-ouvertes.fr/inserm-00483481

S. L. Man, I. Petersen, and M. Thompson, Antiepileptic Drugs during Pregnancy in Primary Care: A UK Population Based Study, PLoS ONE, vol.66, issue.1111/j.1468???1331.2006.01359, pp.523-539, 2012.
DOI : 10.1371/journal.pone.0052339.t001

K. Palmsten, S. Setoguchi, and A. V. Margulis, Elevated risk of preeclampsia in pregnant women with depression: depression or antidepressants? -American journal of epidemiology, pp.175-988, 2012.

K. Palmsten, S. Hernández-díaz, and K. F. Huybrechts, Use of Antidepressants Near Delivery and Risk of Postpartum Hemorrhage, Obstetric Anesthesia Digest, vol.34, issue.3, 2013.
DOI : 10.1097/01.aoa.0000452164.17871.dc

C. Vasilakis-scaramozza, A. Aschengrau, and H. Cabral, Antidepressant use during early pregnancy and the risk of congenital anomalies-Pharmacotherapy, pp.693-700, 2013.

S. Grigoriadis, E. H. Vonderporten, and L. Mamisashvili, The effect of prenatal antidepressant exposure on neonatal adaptation-The journal of clinical psychiatry, pp.309-320, 2013.

M. Steiner, Prenatal exposure to antidepressants: How safe are they? -American journal of psychiatry 169-no, pp.1130-1132, 2012.

H. M. Jensen, R. Gron, and O. Lidegaard, Maternal depression, antidepressant use in pregnancy and apgar scores in infants -The british journal of psychiatry: The journal of mental science, pp.202-347, 2013.

K. Laugesen, M. S. Olsen, and A. B. Andersen, In utero exposure to antidepressant drugs and risk of attention deficit hyperactivity disorder: a nationwide Danish cohort study, BMJ Open, vol.3, issue.9, 2013.
DOI : 10.1136/bmjopen-2013-003507

L. H. Pedersen, T. B. Henriksen, and B. H. Bech, Prenatal antidepressant exposure and behavioral problems in early childhood ? a cohort study-Acta psychiatrica scandinavica, pp.127-129

D. Vera, M. A. Et-berard, and A. , Antidepressant use during pregnancy and the risk of pregnancy-induced hypertension, British Journal of Clinical Pharmacology, vol.60, issue.7, pp.362-369
DOI : 10.1111/j.1365-2125.2012.04196.x

J. Bons, Courrier d'information des modifications des RCP du DEROXAT®disponible aux adresses : ansm

G. Koren and H. M. Et-nordeng, -Selective serotonin reuptake inhibitors and malformations: case closed?-Seminars in fetal and neonatal medicine -18 (1)- Février 2013, pp.19-22
URL : https://hal.archives-ouvertes.fr/hal-01110262

T. W. Sadler, Selective serotonin reuptake inhibitors (SSRIs) and heart defects: Potential mechanisms for the observed associations, Reproductive Toxicology, vol.32, issue.4, pp.484-489, 2011.
DOI : 10.1016/j.reprotox.2011.09.004

M. V. Smith, A. Sung, and B. Shah, Assessment of infants born at term and in utero exposure to serotonin reuptake inhibitors -Early human development, pp.81-86, 2013.

C. R. , G. A. Fleisher, and B. E. , Length of prenatal exposure to selective serotonin reuptake inhibitor (SSRI) antidepressants: effects on neonatal adaptation and psychomotor development, Psychopharmacology, vol.217, issue.2, pp.211-219, 2011.

M. P. Austin, J. C. Karatas, and P. Mishra, Infant neurodevelopment following in utero exposure to antidepressant medication, Acta Paediatrica ?, vol.102, issue.11, pp.1054-1059, 2013.

T. F. Oberlander, -Fetal serotonin signaling: setting pathways for early childhood development and behavior-Journal of adolescent health -51, Août, vol.2012, issue.2, pp.9-16
URL : https://hal.archives-ouvertes.fr/halshs-01400829

L. A. Croen, J. K. Grether, and C. K. Yoshida, Antidepressant use during pregnancy and childhood autism spectrum disorders-Archives of general psychiatry -68 (11) - Novembre, pp.1104-1112, 2011.

A. Einarson, J. Choi, and G. Koren, Outcomes of infants exposed to multiple antidepressants during pregnancy: results of a cohort study-Journal of population therapeutics and clinical pharmacology, pp.182011-390

S. L. Hoog, -Duloxetine and pregnancy outcomes: safety surveillance findings - International journal of medical sciences, pp.413-419
URL : https://hal.archives-ouvertes.fr/hal-00531994

K. N. Polen, S. A. Rasmussen, and T. Riehle-colarusso, Association between reported venlafaxine use in early pregnancy and birth defects, national birth defects prevention study, 1997-2007, Birth Defects Research Part A: Clinical and Molecular Teratology, vol.313, issue.116 Suppl, pp.28-35, 1997.
DOI : 10.1002/bdra.23096

N. Sokover, P. Merlob, and G. Klinger, -Neonatal recurrent prolonged hypothermia associated with maternal mirtazapine treatment during pregnancy -The Canadian journal of clinical pharmacology, pp.188-190, 2008.

T. Takeshi, Antidepressant treatment and relapse of depression during pregnancy, JAMA ? Juillet, vol.296, issue.2, pp.165-170, 2006.

N. Franck and F. Thibaut, -Pharmacologie et mode d'action des neuroleptiques -EMC- Psychiatrie, pp.282-299, 2005.
URL : https://hal.archives-ouvertes.fr/hal-00607361

G. E. Robinson, -Treatment of schizophrenia in pregnancy and postpartum, Journal of population therapeutics and clinical pharmacology ?, vol.19, issue.3, pp.380-386
URL : https://hal.archives-ouvertes.fr/jpa-00209843

M. D. Yaeger, M. D. Smith, and M. D. Altshuler, Atypical antipsychotics in the treatment of schizophrenia during pregnancy and the postpartum -American journal of psychiatry -163 (12) ? Décembre, pp.2064-2070, 2006.

Y. Yeshayahu, -The use of olanzapine in pregnancy and congenital cardiac and musculoskeletal abnormalities-The american journal of psychiatry -164 (11)- Novembre, pp.1759-1760, 2007.

D. Coppola, L. J. Russo, and R. Kwarta, Evaluating the Postmarketing Experience of Risperidone Use During Pregnancy, Drug Safety, vol.20, issue.13, pp.30-33
DOI : 10.2165/00002018-200730030-00006

S. Grover and R. Et-madan, -Successful use of quetiapine in two successive pregnancies - The journal of neuropsychiatry and clinical neurosciences, p.38, 2012.
URL : https://hal.archives-ouvertes.fr/hal-01482901

S. Raha, V. H. Taylor, and A. C. Et-holloway, Effect of Atypical Antipsychotics on Fetal Growth: Is the Placenta Involved?, Journal of Pregnancy, vol.20, issue.1, p.2012
DOI : 10.1016/j.schres.2012.05.010

S. Gentile, Antipsychotic therapy during early and late pregnancy. A systematic review -Schizophrenia Bulletin -36 (3)-Mai, pp.518-544, 2010.

J. J. Newham, S. H. Thomas, and K. Macritchie, Birth weight of infants after maternal exposure to typical and atypical antipsychotics: prospective comparison study -The british journal of psychiatry -192 (5)-Mai, pp.333-337, 2008.

K. C. Johnson, J. L. Laprairie, and P. A. Brennan, Prenatal antipsychotic exposure and neuromotor performance during infancy-Archives of general psychiatry, pp.69-787

B. Wikner, C. O. Stiller, and U. Bergman, -Use of benzodiazepines and benzodiazepine receptor agonists during pregnancy: neonatal outcome and congenital malformations -Pharmacoepidemiology and drug safety, pp.16-1203, 2007.
URL : https://hal.archives-ouvertes.fr/hal-01417410

J. Gidai, N. Acs, and F. Bánhidy, An evaluation of data for 10 children born to mothers who attempted suicide by taking large doses of alprazolam during pregnancy -Toxicology and industrial health, pp.24-25, 2008.

E. Enato, M. Moretti, and G. Et-koren, -The fetal safety of benzodiazepines: an updated meta-analysis -Journal of obstetrics and gynaecology Canada, pp.46-48, 2011.

N. Picard, S. Guénin, Y. Perrin, and G. Hilaire, Prenatal diazepam exposure alters respiratory control system and GABAA and adenosine receptor gene expression in newborn rats -Pediatric research, pp.44-49, 2008.

O. Bonnot, S. E. Vollset, and P. F. Godet, Exposition in utero au lorazépam et atrésie anale : signal épidémiologique-L'Encéphale -29 (6) -Novembre 2013, pp.553-559

S. M. Gilboa, M. J. Strickland, and A. F. Olshan, Use of antihistamine medications during early pregnancy and isolated major malformations -Birth defects research, pp.85-137, 2009.

D. Swortfiguer, H. Cissoko, and B. Giraudeau, -Retentissement néonatal de l'exposition aux benzodiazépines en fin de grossesse -Archives de pédiatrie, pp.12-21

R. Serreau, M. Komiha, and F. Blanc, Neonatal seizures associated with maternal hydroxyzine hydrochloride in late pregnancy-Reproductive toxicology, pp.573-574, 2005.

H. D. Christensen, C. L. Gonzalez, and W. F. Et-rayburn, -Effects from prenatal exposure to alprazolam on the social behavior of mice offspring-American journal of obstetrics and gynecology, pp.1452-1457, 2003.
URL : https://hal.archives-ouvertes.fr/hal-00309466

M. Chauvenet, Méthodologie de l'évaluation des médicaments chez la femme enceinte -Thérapie, pp.247-252, 2003.

A. P. Jonville-béra and T. Et-vial, Médicaments et grossesse : prescrire et évaluer le risque -Edition Elsevier, pp.3-14, 2012.

S. Nezelof and L. Et-mathioly, -L'hospitalisation conjointe mère-bébé-Enfances et Psy - 37 (4)-Novembre, pp.81-89, 2007.
URL : https://hal.archives-ouvertes.fr/inserm-00493033

A. L. Sutter-dallay, -Les unités mère-enfant en psychiatrie périnatale -Le journal des psychologues ? 261 (8)-Août, pp.22-25, 2008.
URL : https://hal.archives-ouvertes.fr/hal-01286113

B. Durand, -Les unités d'hospitalisation conjointe mère-enfant en France : des structures expérimentales ?-Edition Eres -Janvier, pp.169-177, 2001.
URL : https://hal.archives-ouvertes.fr/inserm-00409083

F. Poinso, M. P. Gay, and M. C. Nine, Care in a mother-baby psychiatric unit: analysis of separation at discharge-Archives of women's mental health, pp.49-58, 2002.