C. Grattan, S. Powell, and F. Humphreys, Management and diagnostic guidelines for urticaria and angio-oedema, British Journal of Dermatology, vol.81, issue.4, pp.708-722, 2001.
DOI : 10.1046/j.1365-2133.1998.02175.x

K. Bork, G. Meng, P. Staubach, and J. Hardt, Hereditary Angioedema: New Findings Concerning Symptoms, Affected Organs, and Course, The American Journal of Medicine, vol.119, issue.3, pp.267-74, 2006.
DOI : 10.1016/j.amjmed.2005.09.064

F. Rosen, I. Davis, and . Ae, Deficiencies of C1 inhibitor, Best Practice & Research Clinical Gastroenterology, vol.19, issue.2, pp.251-61, 2005.
DOI : 10.1016/j.bpg.2004.11.011

!. Davis and I. Ae, The pathophysiology of hereditary angioedema, Clinical Immunology, vol.114, issue.1, pp.3-9, 2005.
DOI : 10.1016/j.clim.2004.05.007

M. Bas, V. Adams, T. Suvorava, T. Niehues, T. Hoffman et al., Nonallergic angioedema: role of bradykinin, Allergy, vol.77, issue.6, pp.842-56, 2007.
DOI : 10.1111/j.1398-9995.2006.01197.x

M. Moreau, N. Garbacki, G. Molinaro, N. Brown, F. Marceau et al., The Kallikrein-Kinin System: Current and Future Pharmacological Targets, Journal of Pharmacological Sciences, vol.99, issue.1, pp.6-38, 2005.
DOI : 10.1254/jphs.SRJ05001X

H. Longhurst and M. Cicardi, Hereditary angio-oedema, The Lancet, vol.379, issue.9814, pp.474-81
DOI : 10.1016/S0140-6736(11)60935-5

M. Cugno, R. Castelli, and M. Cicardi, Angioedema due to acquired C1-inhibitor deficiency: A bridging condition between autoimmunity and lymphoproliferation, Autoimmunity Reviews, vol.8, issue.2, pp.156-165, 2008.
DOI : 10.1016/j.autrev.2008.05.003

F. Rosen, P. Charache, J. Pensky, and V. Donaldson, Hereditary Angioneurotic Edema: Two Genetic Variants, Science, vol.148, issue.3672, pp.957-958, 1965.
DOI : 10.1126/science.148.3672.957

D. Miller, S. Oliveria, D. Berlowitz, B. Fincke, P. Stang et al., Angioedema Incidence in US Veterans Initiating Angiotensin-Converting Enzyme Inhibitors, Hypertension, vol.51, issue.6, pp.1624-1654, 2008.
DOI : 10.1161/HYPERTENSIONAHA.108.110270

T. Bowen, M. Cicardi, H. Farkas, and K. Bork, Hilary J Longhurst 2010 International consensus algorithm for the diagnosis, therapy and management of hereditary angioedema Allergy Asthma Clin Immunol, p.24, 2010.

X. Chen, Biochemical Properties of Recombinant Prolyl Dipeptidases DPP-IV and DPP8
DOI : 10.1007/0-387-32824-6_3

E. Waage-nielsen-a,-c, C. Waage-a, H. Fure-b, O. L. Brekke, G. Sfyroera-e et al., Mollnes Effect of supraphysiologic levels of C1-inhibitor on the classical, lectin and alternative pathways of complement, Molecular Immunology, vol.44, pp.1819-1826, 2006.

L. Bergamaschini, . Miedico, . Cicardi, E. Coppola, and A. Faioni, Agostoni Consumption of C4b-binding protein (C4BP) during in vivo activation of the classical complement pathway Clin Exp Immunol, pp.220-224, 1999.

A. Agostoni, E. Aygoren-pursun, K. Binkley, A. Blanch, K. Bork et al., Hereditary and acquired angioedema: Problems and progress: Proceedings of the third C1 esterase inhibitor deficiency workshop and beyond, Journal of Allergy and Clinical Immunology, vol.114, issue.3, pp.51-131, 2004.
DOI : 10.1016/j.jaci.2004.06.047

!. Blanch, A. Roche, O. Urrutia, I. Gamboa, P. Fontan et al., First case of homozygous C1 inhibitor deficiency, Journal of Allergy and Clinical Immunology, vol.118, issue.6, pp.1330-1335, 2006.
DOI : 10.1016/j.jaci.2006.07.035

A. Agostoni and M. Cicardi, Hereditary and Acquired C1-Inhibitor Deficiency, Medicine, vol.71, issue.4, pp.206-221, 1992.
DOI : 10.1097/00005792-199207000-00003

B. Zuraw, Hereditary Angioedema, New England Journal of Medicine, vol.359, issue.10, pp.1027-1063, 2008.
DOI : 10.1056/NEJMcp0803977

M. Cicardi and A. Zanichelli, Acquired angioedema Allergy, Asthma & Clinical Immunology, p.14, 2010.

A. Schreiber, B. Zweiman, P. Atkins, F. Goldwein, P. G. Atkinson et al., Acquired angioedema with lymphoproliferative disorder: association of C1 inhibitor deficiency with cellular abnormality, Blood, vol.48, pp.567-80, 1976.

R. Castelli, D. Deliliers, L. Zingale, E. Pogliani, and M. Cicardi, Lymphoproliferative disease and acquired C1 inhibitor deficiency, Haematologica, vol.92, issue.5, pp.716-724, 2007.
DOI : 10.3324/haematol.10769

L. Bouillet, D. Ponard, H. Rousset, S. Cichon, and C. Drouet, A case of hereditary angio-oedema type III presenting with C1-inhibitor cleavage and a missense mutation in the F12 gene, British Journal of Dermatology, vol.156, issue.5, pp.1063-1068, 2007.
DOI : 10.1210/en.136.11.5076

URL : https://hal.archives-ouvertes.fr/hal-00400125

K. Bork, K. Wulff, J. Hardt, G. Witzke, and P. Staubach, Hereditary angioedema caused by missense mutations in the factor XII gene: Clinical features, trigger factors, and therapy, Journal of Allergy and Clinical Immunology, vol.124, issue.1, pp.129-163, 2009.
DOI : 10.1016/j.jaci.2009.03.038

J. Kostis, M. Packer, H. Black, R. Scmieder, D. Henry et al., Omapatrilat and enalapril in patients with hypertension: the Omapatrilat Cardiovascular Treatment vs. Enalapril (OCTAVE) trial, American Journal of Hypertension, vol.17, issue.2, pp.103-114, 2004.
DOI : 10.1016/j.amjhyper.2003.09.014

Q. Duan, B. Nikpoor, and M. Dubé, A Variant in XPNPEP2 Is Associated with Angioedema Induced by Angiotensin I???Converting Enzyme Inhibitors, The American Journal of Human Genetics, vol.77, issue.4, pp.617-643, 2005.
DOI : 10.1086/496899

B. Haymore, J. Yoon, C. Mikita, M. Klote, and K. Dezee, Risk of angioedema with angiotensin receptor blockers in patients with prior angioedema associatedwith angiotensinconverting enzyme inhibitors: a meta-analysis, 2008.

S. Toh, M. Reichman, M. Houstoun, R. Southworth, M. Ding et al., Comparative Risk for Angioedema Associated With the Use of Drugs That Target the Renin-Angiotensin-Aldosterone System, Archives of Internal Medicine, vol.172, issue.20, pp.1582-1591, 2012.
DOI : 10.1001/2013.jamainternmed.34

C. Beavers, S. Dunn, and T. Macaulay, The role of angiotensin receptor blockers in patients with angiotensin-converting enzyme inhibitor-induced angioedema. Ann Pharmacother, 2011.

M. Bonde, K. Olsen, N. Erikstrup, T. Speerschneider, C. Lyngsø et al., The angiotensin II type 1 receptor antagonist Losartan binds and activates bradykinin B2 receptor signaling, Regulatory Peptides, vol.167, issue.1, pp.21-26, 2011.
DOI : 10.1016/j.regpep.2010.11.003

D. J. Campbell, H. Krum, and M. D. Esler, Losartan Increases Bradykinin Levels in Hypertensive Humans Circulation, pp.315-320, 2005.

H. Farkas, L. Jakab, G. Temesszentandrasi, B. Visy, G. Harmat et al., Hereditary angioedema: A decade of human C1-inhibitor concentrate therapy, Journal of Allergy and Clinical Immunology, vol.120, issue.4, pp.941-948, 2007.
DOI : 10.1016/j.jaci.2007.06.026

M. Bas, H. Bier, J. Greve, G. Kojda, and T. Hoffmann, -receptor antagonist icatibant, Allergy, vol.71, issue.12, pp.1490-1492, 2006.
DOI : 10.2165/00126839-200506040-00008

URL : https://hal.archives-ouvertes.fr/hal-01258379

E. Deeks and . Icatibant, Icatibant, Drugs, vol.123, issue.Suppl., pp.73-81, 2010.
DOI : 10.2165/11204500-000000000-00000

M. Cicardi, A. Banerji, F. Bracho, A. Malbran, B. Rosenkranz et al., Icatibant, a New Bradykinin-Receptor Antagonist, in Hereditary Angioedema, WT. Icatibant, a new bradykininreceptor antagonist, pp.532-573, 2010.
DOI : 10.1056/NEJMoa0906393

A. Agostoni and M. Cicardi, Hereditary and Acquired C1-Inhibitor Deficiency, Medicine, vol.71, issue.4, pp.206-221, 1992.
DOI : 10.1097/00005792-199207000-00003

J. Gelfand, R. Sherins, D. Alling, and M. Frank, Treatment of Hereditary Angioedema with Danazol, New England Journal of Medicine, vol.295, issue.26, pp.1444-1452, 1976.
DOI : 10.1056/NEJM197612232952602

E. Pappalardo, L. Zingale, and M. Cicardi, Increased expression of C1-inhibitor mRNA in patients with hereditary angioedema treated with Danazol, Immunology Letters, vol.86, issue.3, pp.271-277, 2003.
DOI : 10.1016/S0165-2478(03)00029-4

A. Sheffer, K. Austen, and F. Rosen, Tranexamic Acid Therapy in Hereditary Angioneurotic Edema, New England Journal of Medicine, vol.287, issue.9, pp.452-456, 1972.
DOI : 10.1056/NEJM197208312870907

T. Bowen, M. Cicardi, K. Bork, B. Zuraw, M. Frank et al., Hereditary angiodema: a current state-of-the-art review, VII: Canadian Hungarian 2007 International Consensus Algorithm for the Diagnosis, Therapy, and Management of Hereditary Angioedema, Annals of Allergy, Asthma & Immunology, vol.100, issue.1, pp.30-40, 2008.
DOI : 10.1016/S1081-1206(10)60584-4

H. Farkas, G. Fust, B. Fekete, I. Karadi, and L. Varga, Eradication of Helicobacter pylori and improvement of hereditary angioneurotic oedema, The Lancet, vol.358, issue.9294, pp.1695-1701, 2001.
DOI : 10.1016/S0140-6736(01)06720-4

T. Bowen, M. Cicardi, H. Farkas, K. Bork, H. Longhurst et al., 2010 International consensus algorithm for the diagnosis, therapy and management of hereditary angioedema, International consensus algorithm for the diagnosis, therapy and management of hereditary angioedema, p.24, 2010.
DOI : 10.1186/1710-1492-6-24

W. Lumry, A. Castaldo, M. Vernon, M. Blaustein, D. Wilson et al., The humanistic burden of hereditary angioedema: Impact on health-related quality of life, productivity, and depression, Allergy and Asthma Proceedings, vol.31, issue.5, pp.407-421, 2010.
DOI : 10.2500/aap.2010.31.3394

C. Dagen and T. Craig, Treatment of Hereditary Angioedema: items that need to be addressed in practice parameter, Allergy, Asthma & Clinical Immunology, vol.6, issue.1, p.11, 2010.
DOI : 10.1186/1710-1492-6-11

R. Crosher, Intravenous tranexamic acid in the management of hereditary angio-oedema, British Journal of Oral and Maxillofacial Surgery, vol.25, issue.6
DOI : 10.1016/0266-4356(87)90143-4

A. Sheffer, D. Fearon, K. Austen, and F. Rosen, Tranexamic acid: Preoperative prophylactic therapy for patients with hereditary angioneurotic edema, Journal of Allergy and Clinical Immunology, vol.60, issue.1, pp.38-40, 1977.
DOI : 10.1016/0091-6749(77)90080-X

I. Martinez-saguer, E. Rusicke, E. Aygoren-pursun, C. Heller, T. Klingebiel et al., Characterization of acute hereditary angioedema attacks during pregnancy and breast-feeding and their treatment with C1 inhibitor concentrate, American Journal of Obstetrics and Gynecology, vol.203, issue.2, pp.131-132, 2010.
DOI : 10.1016/j.ajog.2010.03.003

K. Obtulowicz, G. Porebski, B. Bilo, M. Stobiecki, and A. Obtulowick, Hereditary angioedema in pregnancy -case series study. The 6th C1-INH Defi ciency Workshop, pp.22-2458, 2009.

T. Caballero, H. Farkas, L. Bouillet, T. Bowen, A. Gompel et al., International consensus and practical guidelines on the gynecologic and obstetric management of female patients with hereditary angioedema caused by C1 inhibitor deficiency, Journal of Allergy and Clinical Immunology, vol.129, issue.2, pp.308-328, 2012.
DOI : 10.1016/j.jaci.2011.11.025

L. Bouillet, H. Longhurst, I. Boccon-gibod, K. Bork, C. Bucher et al., Disease expression in women with hereditary angioedema, American Journal of Obstetrics and Gynecology, vol.199, issue.5, pp.484-485, 2008.
DOI : 10.1016/j.ajog.2008.04.034

URL : https://hal.archives-ouvertes.fr/hal-00400660

L. Beltrami, A. Zanichelli, L. Zingale, R. Vacchini, S. Carugo et al., Long-term follow-up of 111 patients with angiotensin-converting enzyme inhibitor-related angioedema, Journal of Hypertension, vol.29, issue.11, pp.2273-2280, 2011.
DOI : 10.1097/HJH.0b013e32834b4b9b

M. Duerr, P. Glander, F. Diekmann, D. Dragun, H. Neumayer et al., Increased Incidence of Angioedema with ACE Inhibitors in Combination with mTOR Inhibitors in Kidney Transplant Recipients, Clinical Journal of the American Society of Nephrology, vol.5, issue.4, pp.703-711
DOI : 10.2215/CJN.07371009

X. Girerd, O. Hanon, B. Pannier, B. Vaïsse, and J. Mourad, Trends in the use of antihypertensive drugs in France from 2002 to 2012: Flahs surveys, Ann Cardiol Angeiol. Paris, vol.61, issue.3, p.218223, 2013.

X. Girerd and D. Herpin, Change in life style and drug therapy for treatment of hypertension in France between, Arch Mal Coeur, vol.98, pp.813-819, 2002.

E. Slater, D. Merrill, H. Guess, P. Roylance, W. Cooper et al., Clinical Profile of Angioedema Associated With Angiotensin Converting-Enzyme Inhibition, JAMA: The Journal of the American Medical Association, vol.260, issue.7, pp.967-970, 1988.
DOI : 10.1001/jama.1988.03410070095035

M. Lunn, C. Santos, and T. Craig, Is there a need for clinical guidelines in the United States for the diagnosis of hereditary angioedema and the screening of family members of affected patients?, Annals of Allergy, Asthma & Immunology, vol.104, issue.3, pp.211-214, 2010.
DOI : 10.1016/j.anai.2009.12.004

O. Roche, A. Blanch, T. Caballero, N. Sastre, D. Callejo et al., Hereditary angioedema due to C1 inhibitor deficiency: patient registry and approach to the prevalence in Spain, Annals of Allergy, Asthma & Immunology, vol.94, issue.4, pp.498-503, 2005.
DOI : 10.1016/S1081-1206(10)61121-0

A. Stray-pedersen, T. Abrahamsen, and S. Frøland, Primary immunodeficiency diseases in Norway, Journal of Clinical Immunology, vol.20, issue.6, pp.477-485, 2000.
DOI : 10.1023/A:1026416017763

M. Hosotte, S. Jarlot, S. Luyasu, and G. Kanny, Quincke's oedema or angioedema

. Icatibant, Attacks of hereditary angioedema: continue to use C1 esterase inhibitor

B. Zuraw and . Hereditary, Hereditary Angioedema, New England Journal of Medicine, vol.359, issue.10, pp.1027-1036, 2008.
DOI : 10.1056/NEJMcp0803977

K. Bork, S. Barnstedt, P. Koch, and H. Traupe, Hereditary angioedema with normal C1-inhibitor activity in women, The Lancet, vol.356, issue.9225, pp.213-220, 2000.
DOI : 10.1016/S0140-6736(00)02483-1

G. Dewald and K. Bork, Missense mutations in the coagulation factor XII (Hageman factor) gene in hereditary angioedema with normal C1 inhibitor, Biochemical and Biophysical Research Communications, vol.343, issue.4, pp.1286-1295, 2006.
DOI : 10.1016/j.bbrc.2006.03.092

H. Farkas, Pediatric hereditary angioedema due to C1-inhibitor deficiency., Allergy, Asthma & Clinical Immunology, vol.6, issue.1, p.18, 2010.
DOI : 10.1186/1710-1492-6-18

A. Kaplan, Type III hereditary angioedema: defined, but not understood, Annals of Allergy, Asthma & Immunology, vol.109, issue.3, pp.153-157, 2012.
DOI : 10.1016/j.anai.2012.07.007

K. Bork, D. Gul, J. Hardt, and G. Dewald, Hereditary Angioedema with Normal C1 Inhibitor: Clinical Symptoms and Course, The American Journal of Medicine, vol.120, issue.11, pp.987-992, 2007.
DOI : 10.1016/j.amjmed.2007.08.021

J. Winnewisser, M. Rossi, P. Spath, and H. Burgi, Type I hereditary angio-oedema. Variability of clinical presentation and course within two large kindreds, Journal of Internal Medicine, vol.241, issue.1, pp.39-46, 1997.
DOI : 10.1046/j.1365-2796.1997.76893000.x

L. Bouillet, I. Boccon-gibod, D. Ponard, J. Lunardi, N. Monnier et al., Angies hitaire par dicit en C1-inh : expression pathologique partir d'une sie de 180 patients La Revue de Médecine Interne, 2008.

H. Quincke, Concerning the acute localized oedema of the skin, Monatsh Prakt Dermat, vol.I, pp.129-160, 1882.

W. Osler, HEREDITARY ANGIO-NEUROTIC ??DEMA, The American Journal of the Medical Sciences, vol.95, issue.4, pp.362-369, 1888.
DOI : 10.1097/00000441-188804000-00004

J. Nussberger, M. Cugno, C. Amstutz, M. Cicardi, A. Pellacani et al., Plamsa bradykinin in angio-edema. Lancet, pp.1693-1700, 1998.

E. Schremmer-danninger, S. Naidoo, C. Neuhof, K. Valeske, C. Snyman et al., Visualisation of tissue kallikrein, kininogen and kinin receptors in human skin following trauma and in dermal diseases, Biological Chemistry, vol.385, issue.11, pp.1069-76, 2004.
DOI : 10.1515/BC.2004.138

B. Visy, G. Füst, A. Bygum, K. Bork, H. Longhurst et al., Helicobacter pylori Infection as a Triggering Factor of Attacks in Patients with Hereditary Angioedema, Helicobacter, vol.89, issue.3, pp.251-258, 2007.
DOI : 10.1002/pmic.200401094

L. Zingale, L. Beltrami, A. Zanichelli, L. Maggioni, E. Pappalardo et al., Angioedema without urticaria: a large clinical survey, Canadian Medical Association Journal, vol.175, issue.9, pp.1065-70, 2006.
DOI : 10.1503/cmaj.060535

L. Corte, A. Carter, A. Rice, and G. , A functional XPNPEP2 promoter haplotype leads to reduced plasma aminopeptidase P and increased risk of ACE inhibitor-induced angioedema, Human Mutation, vol.23, issue.11, pp.1326-1357, 2011.
DOI : 10.1002/humu.21579

R. Moholisa, B. Rayner, P. Owen, E. Schwager, S. Stark et al., Receptor Polymorphisms and ACE Activity With ACE Inhibitor-Induced Angioedema in Black and Mixed-Race South Africans, The Journal of Clinical Hypertension, vol.68, issue.6, pp.413-422, 2013.
DOI : 10.1111/jch.12104

S. Atlas, The Renin-Angiotensin Aldosterone System: Pathophysiological Role and Pharmacologic Inhibition, Journal of Managed Care Pharmacy, vol.13, issue.8 Supp B, pp.9-20, 2007.
DOI : 10.18553/jmcp.2007.13.s8-b.9

A. Theyab, D. Lee, and A. Khachemoune, Angiotensin-converting enzyme inhibitorinduced angioedema, Cutis. Review, vol.91, issue.1, pp.30-35, 2013.

H. Makani, F. Messerli, and J. Romero, Meta-Analysis of Randomized Trials of Angioedema as an Adverse Event of Renin???Angiotensin System Inhibitors, The American Journal of Cardiology, vol.110, issue.3, pp.383-391, 2012.
DOI : 10.1016/j.amjcard.2012.03.034

K. Bork, Diagnosis and treatment of hereditary angioedema with normal C1 inhibitor, Allergy, Asthma & Clinical Immunology, vol.6, issue.1, p.15, 2010.
DOI : 10.1186/1710-1492-6-15

G. Bertazzoni, M. Spina, M. Scarpellini, F. Buccelletti, D. Simone et al., Drug-induced angioedema: experience of Italian emergency departments, Internal and Emergency Medicine, vol.70, issue.1664, 2009.
DOI : 10.1007/s11739-013-1007-x

C. Gang, C. Lindsell, J. Moellman, W. Sublett, K. Hart et al., Factors associated with hospitalization of patients with angiotensin-converting enzyme inhibitorinduced angioedema. Allergy Asthma Proc, 2013.

J. Byrd, A. Woodard-grice, E. Stone, A. Lucisano, H. Schaefer et al., Association of angiotensin-converting enzyme inhibitor-associated angioedema with transplant and immunosuppressant use, Allergy, vol.54, issue.Pt 1, pp.1381-1388, 2010.
DOI : 10.1111/j.1398-9995.2010.02398.x

J. Ducroix, S. Outurquin, B. Benabes-jezraoui, V. Gras, G. Chaby et al., Angio-??d??mes et inhibiteurs de l'enzyme de conversion de l'angiotensine??: ?? propos de 19??cas, La Revue de M??decine Interne, vol.25, issue.7, pp.501-507, 2004.
DOI : 10.1016/j.revmed.2004.02.024

A. Agostoni, M. Cicardi, M. Cugno, L. Zingale, D. Gioffré et al., Angioedema due to angiotensin-converting enzyme inhibitors, Immunopharmacology, vol.44, issue.1-2, pp.21-26, 1999.
DOI : 10.1016/S0162-3109(99)00107-1

M. Cicardi, L. Zingale, L. Bergamaschini, and A. Agostoni, Angioedema Associated With Angiotensin-Converting Enzyme Inhibitor Use, Archives of Internal Medicine, vol.164, issue.8, pp.910-913, 2004.
DOI : 10.1001/archinte.164.8.910

E. E. Slater, D. D. Merril, H. A. Guess, P. J. Rylance, W. D. Cooper et al., Clinical Profile of Angioedema Associated With Angiotensin Converting-Enzyme Inhibition, JAMA: The Journal of the American Medical Association, vol.260, issue.7, pp.967-970, 1988.
DOI : 10.1001/jama.1988.03410070095035

J. Yayan, Onset of orolingual angioedema after treatment of acute brain ischemia with alteplase depends on the site of brain Ischemia: A meta-analysis, North American Journal of Medical Sciences, vol.5, issue.10, pp.589-93, 1947.
DOI : 10.4103/1947-2714.120794

Y. Okada, K. Shibazaki, K. Sakai, K. Kobayashi, Y. Iguchi et al., Orolingual angioedema as complication after rtPA in stroke patient treated with ACE inhibitor, Rinsho Shinkeigaku, vol.48, p.27880, 2008.

G. Molinaro, N. Gervais, and A. Adam, Biochemical Basis of Angioedema Associated With Recombinant Tissue Plasminogen Activator Treatment: An In Vitro Experimental Approach, Stroke, vol.33, issue.6, p.17126, 2002.
DOI : 10.1161/01.STR.0000017284.77838.87

N. Brown, S. Byiers, D. Carr, M. Maldonado, and B. Warner, Dipeptidyl Peptidase-IV Inhibitor Use Associated With Increased Risk of ACE Inhibitor-Associated Angioedema, Hypertension, vol.54, issue.3, pp.516-539, 2009.
DOI : 10.1161/HYPERTENSIONAHA.109.134197

J. Abbosh, J. Anderson, A. Levine, and W. Kupin, Angiotensin converting enzyme inhibitor-induced angioedema more prevalent in transplant patients, Annals of Allergy, Asthma & Immunology, vol.82, issue.5, pp.473-476, 1999.
DOI : 10.1016/S1081-1206(10)62723-8

J. Byrd, A. Woodard-grice, E. Stone, A. Lucisano, H. Schaefer et al., Association of angiotensin-converting enzyme inhibitor-associated angioedema with transplant and immunosuppressant use, Allergy, vol.54, issue.Pt 1, pp.1381-1388, 2010.
DOI : 10.1111/j.1398-9995.2010.02398.x

G. Stallone, B. Infante, P. Di, A. Schena, G. Grandaliano et al., Sirolimus and angiotensin-converting enzyme inhibitors together induce tongue oedema in renal transplant recipients, Nephrology Dialysis Transplantation, vol.19, issue.11, pp.2906-2908, 2004.
DOI : 10.1093/ndt/gfh352

P. Lykavieris, E. Frauger, D. Habes, O. Bernard, and D. Debray, Angioedema in pediatric liver transplant recipients under tacrolimus immunosuppression, Transplantation, vol.75, issue.1, pp.152-155, 2003.
DOI : 10.1097/00007890-200301150-00027

S. Scharpe, I. Demeester, and G. Vanhoof, Serum dipeptidyl peptidase IV activity in transplant recipients, Clin Chem, vol.36, p.984, 1990.

H. Makani, F. Messerli, and J. Romero, Meta-Analysis of Randomized Trials of Angioedema as an Adverse Event of Renin???Angiotensin System Inhibitors, The American Journal of Cardiology, vol.110, issue.3, pp.383-391, 2012.
DOI : 10.1016/j.amjcard.2012.03.034

K. Bork, D. Gul, J. Hardt, and G. Dewald, Hereditary Angioedema with Normal C1 Inhibitor: Clinical Symptoms and Course, The American Journal of Medicine, vol.120, issue.11, pp.987-992, 2007.
DOI : 10.1016/j.amjmed.2007.08.021

J. Roberts, J. Lee, and D. Marthers, Angiotensin-Converting Enzyme (ACE) Inhibitor Angioedema: The Silent Epidemic, The American Journal of Cardiology, vol.109, issue.5, pp.774-779, 2012.
DOI : 10.1016/j.amjcard.2011.11.014

P. Schmidt, M. Hirschl, and F. Trautinger, Treatment of angiotensin-converting enzyme inhibitor???related angioedema with the bradykinin B2 receptor antagonist icatibant, Journal of the American Academy of Dermatology, vol.63, issue.5, pp.913-917, 2010.
DOI : 10.1016/j.jaad.2010.03.023

M. Bas, J. Greve, and K. Stelter, Therapeutic Efficacy of Icatibant in Angioedema Induced by Angiotensin-Converting Enzyme Inhibitors: A Case Series, Annals of Emergency Medicine, vol.56, issue.3, pp.278-82, 2010.
DOI : 10.1016/j.annemergmed.2010.03.032

M. Gallitelli and M. Alzetta, Icatibant: a novel approach to the treatment of angioedema related to the use of angiotensin-converting enzyme inhibitors, The American Journal of Emergency Medicine, vol.30, issue.8, 2011.
DOI : 10.1016/j.ajem.2011.09.014

L. Bouillet, L???angi??d??me laryng?? induit par les m??dicaments interf??rant avec le m??tabolisme de la bradykinine, Revue Fran??aise d'Allergologie, vol.52, issue.3, pp.157-166, 2012.
DOI : 10.1016/j.reval.2012.01.006

B. Gelée, P. Michel, R. Haas, and F. Boishardy, Angio-??d??me acquis induit par les IEC??: traitement aux urgences par concentr?? de C1 inhibiteur, La Revue de M??decine Interne, vol.29, issue.6, pp.516-525, 2007.
DOI : 10.1016/j.revmed.2007.09.038

E. Nielsen and S. Gramstad, Angioedema from angiotensin-converting enzyme (ACE) inhibitor treated with complement 1 (C1) inhibitor concentrate, Acta Anaesthesiologica Scandinavica, vol.5, issue.Suppl. 1, pp.120-122, 2006.
DOI : 10.1111/j.1399-6576.2005.00819.x

E. Rasmussen and A. Bygum, ACE-inhibitor induced angio-oedema treated with complement C1-inhibitor concentrate, Case Reports, vol.2013, issue.oct04 1, 2013.
DOI : 10.1136/bcr-2013-200652

K. Bork, K. Wulff, G. Witzke, C. Stanger, P. Lohse et al., Antihistamine-resistant Angioedema in Women with Negative Family History: Estrogens and F12 Gene Mutations, The American Journal of Medicine, vol.126, issue.12, pp.1142-1151, 2013.
DOI : 10.1016/j.amjmed.2013.05.017

A. Agostoni and M. Cicardi, Hereditary and Acquired C1-Inhibitor Deficiency, Medicine, vol.71, issue.4, pp.206-215, 1992.
DOI : 10.1097/00005792-199207000-00003

L. Bouillet, D. Launay, O. Fain, I. Boccon-gibod, J. Laurent et al., French National Reference Center for Hereditary Angioedema (CREAK).Hereditary angioedema with C1 inhibitor deficiency: clinical presentation and quality of life of 193 French patients, Ann Allergy Asthma Immunol, 2013.

L. Bouillet, H. Longhurst, and I. Boccon-gibod, Disease expression in women with hereditary angio-oedema, Am J Obstet Gynaecol, vol.199, p.484, 2008.

J. Winnewisser, M. Rossi, P. Spath, and H. Burgi, Type I hereditary angio-oedema. Variability of clinical presentation and course within two large kindreds, Journal of Internal Medicine, vol.241, issue.1, pp.39-46, 1997.
DOI : 10.1046/j.1365-2796.1997.76893000.x

K. Binkley, A. Davis, and . Iii, Clinical, biochemical, and genetic characterization of a novel estrogen-dependent inherited form of angioedema, Journal of Allergy and Clinical Immunology, vol.106, issue.3, pp.546-550, 2000.
DOI : 10.1067/mai.2000.108106

L. Martin, D. Degenne, A. Toutain, D. Ponard, and H. Watier, Hereditary angioedema type III: An additional French pedigree with autosomal dominant transmission, Journal of Allergy and Clinical Immunology, vol.107, issue.4, pp.747-748, 2001.
DOI : 10.1067/mai.2001.114242

S. Cichon, L. Martin, H. Hennies, F. Müller, K. Van-driessche et al., Increased Activity of Coagulation Factor XII (Hageman Factor) Causes Hereditary Angioedema Type III, The American Journal of Human Genetics, vol.79, issue.6, pp.1098-1104, 2006.
DOI : 10.1086/509899

URL : https://hal.archives-ouvertes.fr/hal-00399574

C. Gomez-traseira, A. Lopez-lera, C. Drouet, M. Lopez-trascasa, E. Perez-fernandez et al., Hereditary angioedema caused by the p.Thr309Lys mutation in the F12 gene: A??multifactorial disease, Journal of Allergy and Clinical Immunology, vol.132, issue.4, pp.986-995, 2013.
DOI : 10.1016/j.jaci.2013.04.032

K. Bork, K. Wulff, G. Witzke, C. Stanger, P. Lohse et al., Antihistamine-resistant Angioedema in Women with Negative Family History: Estrogens and F12 Gene Mutations, The American Journal of Medicine, vol.126, issue.12, pp.1142-1151, 2013.
DOI : 10.1016/j.amjmed.2013.05.017

C. Oschatz, C. Maas, B. Lecher, T. Jansen, J. Björkqvist et al., Mast Cells Increase Vascular Permeability by Heparin-Initiated Bradykinin Formation In??Vivo, Immunity, vol.34, issue.2, pp.258-68, 2011.
DOI : 10.1016/j.immuni.2011.02.008

T. Renné, A. Schmaier, K. Nickel, M. Blombäck, and C. Maas, In vivo roles of factor XII, vivoroles of factor XII, pp.4296-303, 2012.
DOI : 10.1182/blood-2012-07-292094

R. Lleonart, B. Andres, and J. Jacob, Mercè Corominas Treatment of Idiopathic Nonhistaminergic Angiodema with Icatibant World Allergy Organ J, p.46, 2012.

A. Agostoni, M. , E. Aygo¨renaygo¨ren-pu¨rsu¨npu¨rsu¨pu¨rsu¨n, M. , K. E. Binkley et al., Hereditary and acquired angioedema: Problems and progress: Proceedings of the third C1 esterase inhibitor deficiency workshop and beyond, MD Hereditary and acquired angioedema: Problems and progress: Proceedings of the third C1 esterase inhibitor deficiency workshop and beyond, pp.51-131, 2003.
DOI : 10.1016/j.jaci.2004.06.047

J. Cesbron, C. Lunardi, and &. Massot, Bouillet Type III hereditary angio-oedema: clinical and biological features in a French cohort, Allergy, vol.65, issue.10, pp.1331-1337, 2010.

!. Zuraw and B. , Hereditary Angioedema, New England Journal of Medicine, vol.359, issue.10, pp.1027-1036, 2008.
DOI : 10.1056/NEJMcp0803977

T. Craig, R. Levy, and R. Wasserman, Efficacy of human C1 esterase inhibitor concentrate compared with placebo in acute hereditary angioedema attacks, Journal of Allergy and Clinical Immunology, vol.124, issue.4, pp.801-808, 2009.
DOI : 10.1016/j.jaci.2009.07.017

M. Cicardi, A. Banerji, and F. Bracho, Icatibant, a New Bradykinin-Receptor Antagonist, in Hereditary Angioedema, New England Journal of Medicine, vol.363, issue.6, pp.532-541, 2010.
DOI : 10.1056/NEJMoa0906393

W. Lumry, H. Li, and R. Levy, Randomized placebo-controlled trial of the bradykinin B2 receptor antagonist icatibant for the treatment of acute attacks of hereditary angioedema: the FAST-3 trial, Annals of Allergy, Asthma & Immunology, vol.107, issue.6, pp.529-537, 2011.
DOI : 10.1016/j.anai.2011.08.015

A. Bouillet, Gompel Benefits of progestin contraception in non-allergic angioedema, Clin Exp Allergy.2013, vol.43, issue.4, pp.475-82

N. Bloom and A. Nair, Malbrán Open-label, multicenter study of self-administered icatibant for attacks of hereditary angioedema, Allergy, 2013.

A. Kaplan, M. Greaves, and . Angioedema, Angioedema, Journal of the American Academy of Dermatology, vol.53, issue.3, pp.373-88, 2005.
DOI : 10.1016/j.jaad.2004.09.032

M. Abajian, A. M?ynek, and M. Maurer, Physical urticaria. Curr Allergy Asthma Rep, 2012.

G. Gleich, A. Schroeter, and P. Marcoux, Episodic Angioedema Associated with Eosinophilia, New England Journal of Medicine, vol.310, issue.25, pp.1621-1627, 1984.
DOI : 10.1056/NEJM198406213102501

N. Cassano, V. Mastrandrea, M. Vestita, and G. Vena, An overview of delayed pressure urticaria with special emphasis on pathogenesis and treatmentd Dermatol Ther, pp.22-28, 2009.

F. Mcduffie, W. Sams, J. Maldonado, P. Andreini, D. Conn et al., Hypocomplementemia with cutaneous vasculitis and arthritis, Mayo Clin Proc, vol.48, pp.340-348, 1973.

T. J. Muckle and W. Wells, Urticaria, deafness, and amyloidosis: a new heredofamilial syndrome, The Quarterly journal of medicine, vol.31, pp.235-248, 1962.

H. De-koning, E. Bodar, J. Van-der-meer, and A. Simon, Schnitzler Syndrome: Beyond the Case Reports: Review and Follow-Up of 94 Patients with an Emphasis on Prognosis and Treatment, Seminars in Arthritis and Rheumatism, vol.37, issue.3, pp.137-148, 2007.
DOI : 10.1016/j.semarthrit.2007.04.001

E. Hernes, . Sd-fossb, . Vaage, . Ogreid, E. Heilo et al., Epirubicin combined with estramustine phosphate in hormone-resistant prostate cancer: a phase II study, British Journal of Cancer, vol.76, issue.1, pp.93-99, 1997.
DOI : 10.1038/bjc.1997.342

C. Rousset-jablonski, J. Thalabard, and A. , Tamoxifen contraindicated in women with hereditary angioedema?, Annals of Oncology, vol.20, issue.7, pp.1281-1286, 2009.
DOI : 10.1093/annonc/mdp295

W. Pichler, R. Lehner, and P. Späth, Recurrent angioedema associated with hypogonadism or anti-androgen therapy, Ann Allergy, vol.63, issue.4, pp.301-306, 1989.

K. Joseph, T. Tholanikunnel, and A. Kaplan, In vitro comparison of bradykinin degradation by aliskiren, a renine inhibitor versus an inhibitor of angiotensine converting enzyme, J Renin Angiotensin Aldosterone Syst, 2013.

D. Campbell, Y. Zhang, D. Kelly, R. Gilbert, D. Mccarthy et al., Aliskiren increases bradykinin and tissue kallikrein mRNA levels in the heart, Clinical and Experimental Pharmacology and Physiology, vol.278, issue.Suppl. 1, pp.623-654, 2011.
DOI : 10.1111/j.1440-1681.2011.05572.x

A. Ali, Pharmacovigilance analysis of adverse event reports for aliskiren hemifumarate, a first-in-class direct renin inhibitor, Therapeutics and Clinical Risk Management, vol.7, pp.337-381, 2009.
DOI : 10.2147/TCRM.S23889

D. Andrade, D. Assis, A. Lima, J. Oliveira, M. Araujo et al., Substrate specificity and inhibition of human kallikrein-related peptidase 3 (KLK3 or PSA) activated with sodium citrate and glycosaminoglycans, Archives of Biochemistry and Biophysics, vol.498, issue.1, pp.74-82, 2010.
DOI : 10.1016/j.abb.2010.03.022

K. Mavridis, M. Avgeris, and A. Scorilas, Targeting kallikrein-related peptidases in prostate cancer, Expert Opinion on Therapeutic Targets, vol.6, issue.4, pp.365-83
DOI : 10.1002/pros.22667

M. Ba?, J. Greve, T. Hoffmann, A. Reshef, W. Aberer et al., Repeat treatment with icatibant for multiple hereditary angioedema attacks: FAST-2 open-label study, Allergy, vol.67, issue.11, pp.1452-1461, 2013.
DOI : 10.1111/all.12244

T. Craig, E. Aygören-pürsün, K. Bork, T. Bowen, H. Boysen et al., WAO Guideline for the Management of Hereditary Angioedema, World Allergy Organization Journal, vol.5, issue.12, pp.182-99, 2012.
DOI : 10.1097/WOX.0b013e318279affa

M. Cugno, J. Nussberger, M. Cicardi, and A. Agostoni, Bradykinin and the pathophysiology of angioedema, International Immunopharmacology, vol.3, issue.3, pp.311-317, 2003.
DOI : 10.1016/S1567-5769(02)00162-5

M. Cicardi, W. Aberer, A. Banerji, M. Bas, J. Bernstein et al., Classification, diagnosis, and approach to treatment for angioedema: consensus report from the Hereditary Angioedema International Working Group, Allergy, vol.6, issue.Suppl 3, 2014.
DOI : 10.1111/all.12380

A. Lopez-lera, B. Favier, R. De-la-cruz, S. Garrido, C. Drouet et al., A new case of homozygous C1-inhibitor deficiency suggests a role for Arg378 in the control of kinin pathway activation, Journal of Allergy and Clinical Immunology, vol.126, issue.6, pp.1307-1310, 2010.
DOI : 10.1016/j.jaci.2010.07.037

A. Blanch, O. Roche, I. Urrutia, P. Gamboa, G. Fontan et al., First case of homozygous C1 inhibitor deficiency, Journal of Allergy and Clinical Immunology, vol.118, issue.6, pp.1330-1335, 2006.
DOI : 10.1016/j.jaci.2006.07.035

V. Bafunno, C. Divella, F. Sessa, G. Tiscia, G. Castellano et al., De novo homozygous mutation of the C1 inhibitor gene in a patient with hereditary angioedema, Journal of Allergy and Clinical Immunology, vol.132, issue.3, pp.748-750, 2013.
DOI : 10.1016/j.jaci.2013.04.006