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Master Thesis

Propriétés pharmacologiques de l’oléorésine naturelle de copaïba et tests antibactériens

Abstract : Used in traditional medicine for centuries, copaiba oleoresin, is a resinous fluid directly extracted by drilling the Copaifera tree trunk, which grows in all tropical areas of Latin America and West Africa. It has many pharmacological properties such as being anti-inflammatory, immunomodulating, wound healing, cancer, gastroprotective. This oleoresin is chemically composed mainly of sesquiterpenes such as β-caryophyllene which is the dominant compound, and some diterpenes. After GC-MS characterization of commercial copaiba oleoresin from Brazil, the oleoresin was tested free, micro-encapsulated or incorporated in plastic films. Antibacterial tests on solid and liquid media showed antibacterial properties of copaiba oleoresin on gram-positive bacterium, Bacillus subtilis. These properties were retained when the oleoresin is microencapsulated, incorporated or coated on plastic films. Because of its pharmacological properties, Copaiba oleoresin could be used in different areas as therapeutic (e.g. to treat leishmaniasis, psoriasis) or as preservative in cosmetics or active packaging.
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Master Thesis
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Submitted on : Wednesday, January 28, 2015 - 9:03:15 AM
Last modification on : Tuesday, May 11, 2021 - 11:36:17 AM
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  • HAL Id : dumas-01110359, version 1


Maroi Mahrous. Propriétés pharmacologiques de l’oléorésine naturelle de copaïba et tests antibactériens. Sciences pharmaceutiques. 2015. ⟨dumas-01110359⟩



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