P. Andersen, S. Sundberg, O. Sveen, and H. Wigström, Specific long-lasting potentiation of synaptic transmission in hippocampal slices, Nature, vol.263, issue.5604, pp.736-743, 1977.
DOI : 10.1016/0006-8993(71)90508-7

I. Antonijevic, Depressive disorders -is it time to endorse different pathophysiologies? Psychoneuroendocrinology, pp.1-15, 2006.

R. Armitage, Sleep and circadian rhythms in mood disorders, Acta Psychiatrica Scandinavica, vol.29, issue.5, pp.104-115, 2007.
DOI : 10.1111/j.1399-5618.2004.00180.x

V. Balanzá-martínez, C. Rubio, and G. Selva-vera, Neurocognitive endophenotypes (Endophenocognitypes) from studies of relatives of bipolar disorder subjects: A systematic review, Neuroscience & Biobehavioral Reviews, vol.32, issue.8, pp.1426-1464, 2008.
DOI : 10.1016/j.neubiorev.2008.05.019

M. Basso and R. Bornstein, Relative memory deficits in recurrent versus first-episode major depression on a word-list learning task., Neuropsychology, vol.13, issue.4, pp.557-563, 1999.
DOI : 10.1037/0894-4105.13.4.557

M. Basso, N. Lowery, C. Ghormley, and D. Combs, Comorbid anxiety corresponds with neuropsychological dysfunction in unipolar depression, Cognitive Neuropsychiatry, vol.11, issue.5, pp.437-456, 2007.
DOI : 10.1016/S0925-4927(97)00065-6

R. Beach, S. Bathgate, and C. Cotman, Identification of cell types in rat hippocampal slices maintained in organotypic cultures, Developmental Brain Research, vol.3, issue.1, pp.3-20, 1982.
DOI : 10.1016/0165-3806(82)90071-2

C. Bearden, D. Glahn, and E. Monkul, Patterns of memory impairment in bipolar disorder and unipolar major depression, Psychiatry Research, vol.142, issue.2-3, pp.139-150, 2006.
DOI : 10.1016/j.psychres.2005.08.010

C. Bearden, P. Thompson, and R. Dutton, Three-Dimensional Mapping of Hippocampal Anatomy in Unmedicated and Lithium-Treated Patients with Bipolar Disorder, Neuropsychopharmacology, vol.157, issue.6
DOI : 10.1126/science.1077775

P. Bech and J. Rafaelsen, The use of rating scales exemplified by a comparison of the Hamilton and the Bech-Rafaelsen Melancholia Scale, Acta Psychiatrica Scandinavica, vol.131, issue.Suppl.
DOI : 10.1111/j.1600-0447.1980.tb07683.x

G. Bertschy, D??pressions s??v??res : r??currence et chronicit??, L'Enc??phale, vol.35, 2009.
DOI : 10.1016/S0013-7006(09)73481-5

M. Boldrini, M. Underwood, and R. Hen, Antidepressants increase neural progenitor cells in the human hippocampus, Neuropsychopharmacology, vol.296, issue.11, pp.2376-89, 2009.
DOI : 10.1038/npp.2009.75

T. Bolwig and O. Jorgensen, Electroconvulsive Therapy Effects on Synaptic Proteins, Annals of the New York Academy of Sciences, vol.56, issue.1 Electroconvul
DOI : 10.1007/BF01259345

T. Bolwig and T. Madsen, Electroconvulsive therapy in melancholia: the role of hippocampal neurogenesis, Acta Psychiatrica Scandinavica, vol.96, issue.s433, pp.130-135, 2007.
DOI : 10.1016/j.biopsych.2005.08.032

M. Bouvard and J. Cottraux, Protocoles et échelles d'évaluation en psychiatrie et en psychologie, 2002.

C. Bowie, M. Gupta, and K. Holshausen, Cognitive remediation for treatmentresistant depression: effects on cognition and functioning and the role of online homework. The Journal of Nervous and Mental Disease, pp.680-685, 0201.

J. Bremner, M. Narayan, and E. Anderson, Hippocampal Volume Reduction in Major Depression, American Journal of Psychiatry, vol.157, issue.1, pp.115-117, 1999.
DOI : 10.1176/ajp.157.1.115

W. Brown, Treatment response in melancholia Acta Psychiatrica Scandinavica Supplément 433, Feb, vol.115, pp.125-129, 2007.

D. Burt, M. Zembar, and G. Niederehe, Depression and memory impairment: A meta-analysis of the association, its pattern, and specificity., Psychological Bulletin, vol.117, issue.2, 1995.
DOI : 10.1037/0033-2909.117.2.285

M. Caeser and A. Aertsen, Morphological organization of rat hippocampal slice cultures, The Journal of Comparative Neurology, vol.264, issue.1
DOI : 10.1002/cne.903070109

S. Cajal, Histologie du système nerveux de l'homme et des vertébrés Paris: Maloine. 1911. 23. Campbell S, MacQueen G. The role of the hippocampus in the pathophysiology of major depression, Journal of Psychiatry & Neuroscience, vol.29, issue.6, pp.417-426, 2004.

S. Campbell, M. Marriott, and C. Nahmias, Lower Hippocampal Volume in Patients Suffering From Depression: A Meta-Analysis, American Journal of Psychiatry, vol.161, issue.4, 2004.
DOI : 10.1176/appi.ajp.161.4.598

B. Carroll, F. Cassidy, and D. Naftolowitz, Pathophysiology of hypercorticism in depression, Acta psychiatric Scandinavica Supplementum, vol.433, pp.90-103, 2007.

B. Carroll, M. Feinberg, and J. Greden, A specific laboratory test for the diagnosis of melancholia. Standardization, validation, and clinical utility. Archives of General Psychiatry, pp.15-22, 1981.

B. Carroll, F. Martin, and B. Davies, Resistance to Suppression by Dexamethasone of Plasma 11-O.H.C.S. Levels in Severe Depressive Illness, BMJ, vol.3, issue.5613, pp.285-287, 1968.
DOI : 10.1136/bmj.3.5613.285

B. Casey, C. Glatt, and N. Tottenham, Brain-derived neurotrophic factor as a model system for examining gene by environment interactions across development, Neuroscience, vol.164, issue.1, pp.108-120, 2009.
DOI : 10.1016/j.neuroscience.2009.03.081

G. Chelune, R. Bornstein, and A. Prifitera, The Wechsler Memory Scale???Revised
DOI : 10.1007/978-1-4613-0555-2_3

M. Chen, J. Hamilton, and I. Gotlib, Dicreased hippocampal volume in healthy girls at risk of depression. Archives of general psychiatry, pp.270-276, 2010.

L. Clark, S. Iversen, and G. Goodwin, Sustained attention deficit in bipolar disorder, The British Journal of Psychiatry, vol.180, issue.4, pp.313-319, 2002.
DOI : 10.1192/bjp.180.4.313

L. Clark, A. Sarna, and G. Goodwin, Impairment of Executive Function But Not Memory in First-Degree Relatives of Patients With Bipolar I Disorder and in Euthymic Patients With Unipolar Depression, American Journal of Psychiatry, vol.162, issue.10, pp.1980-1982, 2005.
DOI : 10.1176/appi.ajp.162.10.1980

E. Corruble, D??pression r??currente et ??v??nements de vie : de la clinique ?? de nouveaux mod??les explicatifs ? Enqu??te ACTUEL, L'Enc??phale, vol.32, issue.6, pp.983-987, 2006.
DOI : 10.1016/S0013-7006(06)76277-7

D. Dowlatshahi, G. Macqueen, and J. Wang, Increased temporal cortex CREB concentration and antidepressant treatment in major depression Neuronal plasticity and survival in mood disorders, Lancet. Biological Psychiatry, vol.35248, issue.45, pp.1754-1755732, 1998.

R. Duman, S. Nakagawa, and J. Malberg, Regulation of Adult Neurogenesis by Antidepressant Treatment, Neuropsychopharmacology, vol.25, issue.6, pp.836-880, 2001.
DOI : 10.1016/S0893-133X(01)00358-X

R. Duman, Pathophysiology of depression: the concept of synaptic plasticity1, European Psychiatry, vol.17, issue.3, pp.306-310, 2002.
DOI : 10.1016/S0924-9338(02)00654-5

R. Duman and B. Voleti, Signaling pathways underlying the pathophysiology and treatment of depression: novel mechanisms for rapid-acting agents, Trends in Neurosciences, vol.35, issue.1, 2012.
DOI : 10.1016/j.tins.2011.11.004

T. Dusouchet, M. Bret, B. P. Eich, T. Metcalfe, and J. , Antidépresseurs : caractéristiques et modalités d'utilisation des IRSS, IRSNa et NaSSA Le pharmacien hospitalier Effects of the stress of marathon running on implicit and explicit memory, Psychonomic Bulletin & Review, vol.4116, issue.503, pp.25-31475, 2006.

S. El-badri, D. Cousins, and S. Parker, Magnetic resonance imaging abnormalities in young euthymic patients with bipolar affective disorder. The British Journal of Psychiatry, pp.81-82, 2006.

S. Elgama, S. Denburg, and M. Marriott, Clinical factors that predict cognitive function in patients with major depression. The Canadian Journal of Psychiatry, pp.653-661, 2010.

R. Elliott, B. Sahakian, and A. Mckay, Neuropsychological impairments in unipolar depression: the influence of perceived failure on subsequent performance. Psychological Medicine, pp.975-89, 1996.

R. Elwood, The California Verbal Learning Test: Psychometric characteristics and clinical application, Neuropsychology Review, vol.99, issue.Suppl., pp.173-201, 1995.
DOI : 10.1007/BF02214761

D. Glahn, J. Robinson, and D. Tordesillas-gutierrez, Fronto-temporal dysregulation in asymptomatic bipolar I patients: A paired associate functional MRI study, Human Brain Mapping, vol.299, issue.Suppl 1, pp.1041-1051, 2010.
DOI : 10.1002/hbm.20918

C. Goeldner, T. Ballard, and F. Knoflach, Cognitive impairment in major depression and the mGlu2 receptor as a therapeutic target, Neuropharmacology, vol.64, pp.337-346, 2013.
DOI : 10.1016/j.neuropharm.2012.08.001

P. Gold and G. Chrousos, Organization of the stress system and its dysregulation in melancholic and atypical depression: high vs low CRH/NE states, Molecular Psychiatry, vol.7, issue.3, pp.254-275, 2002.
DOI : 10.1038/sj.mp.4001032

P. Gorwood, E. Corruble, B. Falissard, and G. Goodwin, Toxic Effects of Depression on Brain Function: Impairment of Delayed Recall and the Cumulative Length of Depressive Disorder in a Large Sample of Depressed Outpatients, American Journal of Psychiatry, vol.165, issue.6, pp.731-739, 2008.
DOI : 10.1176/appi.ajp.2008.07040574

P. Gorwood, D??pressions r??cidivantes : neurotoxicit?? des ??pisodes et pr??vention des r??currences, L'Enc??phale, vol.36, issue.5, pp.136-139, 2010.
DOI : 10.1016/S0013-7006(10)70046-4

P. Gorwood, F. Rouillon, and C. Even, Treatment response in major depression: effects of personality dysfunction and prior depression, The British Journal of Psychiatry, vol.196, issue.2, pp.139-142, 2010.
DOI : 10.1192/bjp.bp.109.067058

M. Goudemand, Les états dépressifs Chapitre 17 de Guelfi JD : psychopathologie quantitative et psychométrie de la dépression. Médecine sciences, Lavoisier, pp.142-151, 2010.

E. Gould, H. Cameron, and D. Daniels, Adrenal hormones suppress cell division in the adult rat dentate gyrus, Journal of Neuroscience, vol.12, issue.9, pp.3642-3650, 1992.

E. Gould, P. Tanapat, and B. Mcewen, Proliferation of granule cell precursors in the dentate gyrus of adult monkeys is diminished by stress, Proceedings of the National Academy of Sciences, vol.95, issue.6, pp.3168-3171, 1998.
DOI : 10.1073/pnas.95.6.3168

M. Gourovitch, E. Torrey, and J. Gold, Neuropsychological performance of monozygotic twins discordant for bipolar disorder. Biological Psychiatry, pp.639-646, 1999.

D. Greenberg, M. Payne, and J. Macfall, Hippocampal volumes and depression subtypes, Psychiatry Research: Neuroimaging, vol.163, issue.2, pp.126-132, 2008.
DOI : 10.1016/j.pscychresns.2007.12.009

E. Grober, H. Buschke, and H. Crystal, Screening for dementia by memory testing, Neurology, vol.38, issue.6
DOI : 10.1212/WNL.38.6.900

C. Gualtieri, L. Johnson, and K. Benedict, Neurocognition in depression:patients on and off medication versus healthy comparison subjects. The Journal of neuropsychiatry and clinical neurosciences, pp.217-225, 2006.

P. Hardy, Dépressions sévères : morbi-mortalité et suicides. L'encéphale, 2009.

P. Hardy and P. Gorwood, Impact des évènements de vie dans l'évolution de la dépression

R. F. Haskett, Electroconvulsive Therapy???s Mechanism of Action, The Journal of ECT, vol.30, issue.2, pp.107-110, 2014.
DOI : 10.1097/YCT.0000000000000143

J. Hellsten, M. Wennström, and P. Mohapel, Electroconvulsive seizures increase hippocampal neurogenesis after chronic corticosterone treatment. The European Journal of Neuroscience, pp.283-290, 2002.

I. Herrera-guzmán, E. Gudayol-ferré, and J. Herrera-abarca, Major Depressive Disorder in recovery and neuropsychological functioning: Effects of selective serotonin reuptake inhibitor and dual inhibitor depression treatments on residual cognitive deficits in patients with Major Depressive Disorder in recovery, Journal of Affective Disorders, vol.123, issue.1-3, 2010.
DOI : 10.1016/j.jad.2009.10.009

I. Herrera-guzmán, J. Herrera-abarca, and E. Gudayol-ferré, Effects of selective serotonin reuptake and dual serotonergic???noradrenergic reuptake treatments on attention and executive functions in patients with major depressive disorder, Psychiatry Research, vol.177, issue.3, 2010.
DOI : 10.1016/j.psychres.2010.03.006

I. Hickie, S. Naismith, and P. Ward, Reduced hippocampal volumes and memory loss in patients with early- and late-onset depression, The British Journal of Psychiatry, vol.186, issue.3, 2005.
DOI : 10.1192/bjp.186.3.197

M. Husain, A. Rush, and M. Fink, Speed of Response and Remission in Major Depressive Disorder With Acute Electroconvulsive Therapy (ECT), The Journal of Clinical Psychiatry, vol.65, issue.4, pp.485-491, 2004.
DOI : 10.4088/JCP.v65n0406

L. Jones, M. Payne, and D. Messer, Temporal lobe volume in bipolar disorder: Relationship with diagnosis and antipsychotic medication use, Journal of Affective Disorders, vol.114, issue.1-3, pp.1-350, 2009.
DOI : 10.1016/j.jad.2008.07.003

O. Jorgensen, E. Bock, and P. Bech, Synaptic membrane protein D2 in the cerebrospinal fluid of manic-melancholic patients, Acta Psychiatrica Scandinavica, vol.125, issue.1, 1977.
DOI : 10.1016/0003-2697(66)90246-6

O. Jorgensen and P. Riederer, Increased synaptic markers in hippocampus of depressed patients, Journal of Neural Transmission, vol.125, issue.Suppl. 1, pp.55-66, 1985.
DOI : 10.1007/BF01259345

R. Jouvent, D. Frechette, and F. Binoux, Le ralentissement psychomoteur dans les états dépressifs : construction d'une échelle d'évaluation quantitative. L'encéphale, pp.41-58, 1980.

C. Kellner, M. Fink, and R. Knapp, Relief of Expressed Suicidal Intent by ECT: A Consortium for Research in ECT Study, American Journal of Psychiatry, vol.162, issue.5, pp.977-82, 2005.
DOI : 10.1176/appi.ajp.162.5.977

K. Kendler, J. Kuhn, and J. Vittum, The Interaction of Stressful Life Events and a Serotonin Transporter Polymorphism in the Prediction of Episodes of Major Depression, Archives of General Psychiatry, vol.62, issue.5, pp.529-535, 2005.
DOI : 10.1001/archpsyc.62.5.529

R. Kessler, P. Berglund, and O. Demler, Lifetime Prevalence and Age-of-Onset Distributions of DSM-IV Disorders in the National Comorbidity Survey Replication, Archives of General Psychiatry, vol.62, issue.6, pp.593-602, 2005.
DOI : 10.1001/archpsyc.62.6.593

R. Kessler, P. Berglund, and O. Demler, The Epidemiology of Major Depressive Disorder, JAMA, vol.289, issue.23, pp.3095-3105, 2003.
DOI : 10.1001/jama.289.23.3095

J. Kim and D. Diamond, The stressed hippocampus, synaptic plasticity and lost memories

J. Konarski, R. Mcintyre, and S. Kennedy, Volumetric neuroimaging investigations in mood disorders: bipolar disorder versus major depressive disorder. Bipolar Disorders, 2008.

D. Kondziella, J. Strandberg, C. Lindquist, and F. Asztely, Lamotrigine increases the number of BrdU-labeled cellsinthe rat hippocampus, NeuroReport, vol.22, issue.2, pp.97-100, 2011.
DOI : 10.1097/WNR.0b013e328342d2fa

J. Kragh, T. Bolwig, and D. Woldbye, Electroconvulsive shock and lidocaine-induced seizures in the rat activate astrocytes as measured by glial fibrillary acidic protein, Biological Psychiatry, vol.33, issue.11-12, pp.794-800, 1993.
DOI : 10.1016/0006-3223(93)90020-E

J. Krogh, E. Rostrup, and C. Thomsen, The effect of exercise on hippocampal volume and neurotrophines in patients with major depression???A randomized clinical trial, Journal of Affective Disorders, vol.165, pp.24-30
DOI : 10.1016/j.jad.2014.04.041

K. Kronmüller, J. Pantel, and B. Gotz, Life events and hippocampal volume in first-episode major depression, Journal of Affective Disorders, vol.110, issue.3, pp.241-247, 2008.
DOI : 10.1016/j.jad.2008.01.022

S. Kulkarni, S. Jain, J. Reddy, and Y. , Impairment of verbal learning and memory and executive function in unaffected siblings of probands with bipolar disorder, Bipolar Disorders, vol.141, issue.Suppl. 20
DOI : 10.1111/j.1399-5618.2010.00857.x

G. Laje, S. Paddock, and H. Manji, Genetic markers of suicidal ideation emerging during citalopram treatment of major depression, American Journal of Psychiatry, 2007.

P. Mitchell, Validity of the CORE: I, a neuroendocrinological strategy, in Melancholia: a disorder of movement and mood: a phenomenological and neurobiological review

R. Mojtabai, E. Bromet, and P. Harvey, Neuropsychological Differences Between First-Admission Schizophrenia and Psychotic Affective Disorders, American Journal of Psychiatry, vol.157, issue.9, pp.1453-1460, 2000.
DOI : 10.1176/appi.ajp.157.9.1453

T. Mueller, A. Leon, and M. Keller, Recurrence after recovery from major depressive disorder during 15 years of observational follow-up, American Journal of Psychiatry, vol.156, issue.57, pp.1000-1006, 1999.

J. Murrough, A. Perez, and S. Pillemer, Rapid and Longer-Term Antidepressant Effects of Repeated Ketamine Infusions in Treatment-Resistant Major Depression, Biological Psychiatry, vol.74, issue.4, pp.250-256, 2013.
DOI : 10.1016/j.biopsych.2012.06.022

H. Nasrallah, T. Hopkins, and S. Pixley, Differential effects of antipsychotic and antidepressant drugs on neurogenic regions in rats, Brain Research, vol.1354, pp.23-29, 20100.
DOI : 10.1016/j.brainres.2010.07.075

R. Nehra, S. Chakrabarti, B. Pradhan, and N. Khehra, Comparison of cognitive functions between first- and multi-episode bipolar affective disorders, Journal of Affective Disorders, vol.93, issue.1-3, pp.1-3185, 2006.
DOI : 10.1016/j.jad.2006.03.013

H. Nelson and J. Willison, The National Adult Reading Scale (NART). Part I: The original study NART and WAIS (1982). [ressource en ligne] Disponible sur

A. Neumeister, S. Wood, and O. Bonne, Reduced hippocampal volume in unmedicated, remitted patients with major depression versus control subjects. Biological Pasychiatry, 2005.

P. Nordanskog, U. Dahlstrand, and M. Larsson, Increase in Hippocampal Volume After Electroconvulsive Therapy in Patients With Depression, The Journal of ECT, vol.26, issue.1, pp.62-69, 2010.
DOI : 10.1097/YCT.0b013e3181a95da8

T. Okamoto, R. Yoshimura, and A. Ikenouchi-sugita, Efficacy of electroconvulsive therapy is associated with changing blood levels of homovanillic acid and brain-derived neurotrophic factor (BDNF) in refractory depressed patients: A pilot study, Progress in Neuro-Psychopharmacology and Biological Psychiatry, vol.32, issue.5, pp.1185-1190, 2008.
DOI : 10.1016/j.pnpbp.2008.02.009

U. Ösby, L. Brandt, and N. Correia, Excess Mortality in Bipolar and Unipolar Disorder in Sweden, Archives of General Psychiatry, vol.58, issue.9, pp.844-850, 2001.
DOI : 10.1001/archpsyc.58.9.844

W. Ottowitz, D. Dougherty, and C. Savage, The Neural Network Basis for Abnormalities of Attention and Executive Function in Major Depressive Disorder: Implications for Application of the Medical Disease Model to Psychiatric Disorders, Harvard Review of Psychiatry, vol.10, issue.2, pp.86-99, 2002.
DOI : 10.1080/10673220216210

Y. Papakostas, M. Fink, and J. Lee, Neuroendocrine measures in psychiatric patients: course and outcome with ECT. Psychiatry Research, Feb, vol.4, issue.1, pp.55-64, 1981.

G. Parker, Defining melancholia: the primacy of psychomotor disturbance, Acta Psychiatrica Scandinavica, vol.142, issue.s433, pp.21-30, 2007.
DOI : 10.1016/0165-0327(92)90056-C

G. Parker, M. Fink, and E. Shorter, Issues for DSM-5: Whither Melancholia? The Case for Its Classification as a Distinct Mood Disorder, American Journal of Psychiatry, vol.167, issue.7, 2010.
DOI : 10.1176/appi.ajp.2010.09101525

G. Patki, N. Solanki, and F. Atrooz, Depression, anxiety-like behavior and memory impairment are associated with increased oxidative stress and inflammation in a rat model of social stress, Brain Research, vol.1539, pp.73-86, 2013.
DOI : 10.1016/j.brainres.2013.09.033

A. Pedersen, K. Küppers, and A. Behnkena, Implicit and explicit procedural learning in patients recently remitted from severe major depression Psychiatric Research, 2009.

G. Pedrides, M. Fink, and M. Husain, ECT Remission Rates in Psychotic Versus Nonpsychotic Depressed Patients: A Report from CORE, The Journal of ECT, vol.17, issue.4, 2001.
DOI : 10.1097/00124509-200112000-00003

M. Ritchey, F. Dolcos, and K. Eddington, Neural correlates of emotional processing in depression: Changes with cognitive behavioral therapy and predictors of treatment response, Journal of Psychiatric Research, vol.45, issue.5
DOI : 10.1016/j.jpsychires.2010.09.007

J. Robinson, C. Bearden, and E. Monkul, Fronto-temporal dysregulation in remitted bipolar patients: an fMRI delayed-non-match-to-sample (DNMS) study, Bipolar Disorders, vol.162, issue.Suppl. 1
DOI : 10.1111/j.1399-5618.2009.00703.x

B. Rodriguez, R. Weisberg, and M. Pagano, Frequency and patterns of psychiatric comorbidity in a sample of primary care patients with anxiety disorders, Comprehensive Psychiatry, vol.45, issue.2, pp.129-137, 2004.
DOI : 10.1016/j.comppsych.2003.09.005

R. Sapolsky, Glucocorticoids and Hippocampal Atrophy in Neuropsychiatric Disorders, Archives of General Psychiatry, vol.57, issue.10, pp.925-935, 2000.
DOI : 10.1001/archpsyc.57.10.925

R. Sapolsky, Is impaired neurogenesis relevant to the affective symptoms of depression? Biological Psychiatry, pp.137-139, 2004.

R. Sapolsky, L. Krey, and B. Mcewen, Glucocorticoid-sensitive hippocampal neurons are involved in terminating the adrenocortical stress response., Proceedings of the National Academy of Sciences of the United States of America, pp.6174-6177, 1984.
DOI : 10.1073/pnas.81.19.6174

A. Schatzberg, Major depression: causes or effects? American Journal of Psychiatry, pp.1077-1079, 2002.

J. Schmitt, M. Kruizinga, and W. Riedel, Non-serotonergic pharmacological profiles and associated cognitive effects of serotonin reuptake inhibitors, Journal of Psychopharmacology, vol.12, issue.3, pp.173-179, 2001.
DOI : 10.1177/026988110101500304

G. Serafini, Neuroplasticity and major depression, the role of modern antidepressant drugs, World Journal of Psychiatry, vol.2, issue.3, pp.49-57
DOI : 10.5498/wjp.v2.i3.49

Y. Sheline, 3D MRI studies of neuroanatomic changes in unipolar major depression: the role of stress and medical comorbidity, Biological Psychiatry, vol.48, issue.8, pp.791-800, 2000.
DOI : 10.1016/S0006-3223(00)00994-X

Y. Sheline, M. Gado, and H. Kraemer, Untreated Depression and Hippocampal Volume Loss, American Journal of Psychiatry, vol.160, issue.8, pp.1516-1524, 2003.
DOI : 10.1176/appi.ajp.160.8.1516

Y. Sheline, B. Mittler, and M. Mintun, The hippocampus and depression1, European Psychiatry, vol.17, issue.3, pp.300-305, 2002.
DOI : 10.1016/S0924-9338(02)00655-7

Y. Sheline, M. Shanghavi, and M. Mintun, Depression duration but not age predicts hippocampal volume loss in medically healthy women with recurrent major depression. The Journal of Neuroscience, pp.5034-5043, 1999.

Y. Shirayama, A. Chen, and S. Nakagawa, Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression. The Journal of Neuroscience, pp.3251-3261, 2002.

J. Siuciak, D. Lewis, and S. Wiegand, Antidepressant-Like Effect of Brain-derived Neurotrophic Factor (BDNF), Pharmacology Biochemistry and Behavior, vol.56, issue.1, pp.131-138, 1997.
DOI : 10.1016/S0091-3057(96)00169-4

D. Smith, W. Muir, and D. Blackwood, Neurocognitive impairment in euthymic young adults with bipolar spectrum disorder and recurrent major depressive disorder, Bipolar Disorders, vol.12, issue.1, pp.40-46, 2006.
DOI : 10.1016/S0006-3223(00)01020-9

M. Smith, S. Makino, and R. Kvetnansky, Stress alters the expression of brain-derived neurotrophic factor and neurotrophin-3 mRNAs in the hippocampus, The Journal of Neuroscience, vol.15, pp.1768-1777, 1995.

C. Soriano-mas, R. Hernández-ribas, and J. Pujol, Cross-sectional and longitudinal assessment of structural brain alterations in melancholic depression. Biological Psychiatry, Feb, vol.69, issue.4, pp.318-325, 2011.

L. Squire, Memory Functions as Affected by Electroconvulsive Therapy, Annals of the New York Academy of Sciences, vol.138, issue.10, pp.307-314, 1986.
DOI : 10.1016/0031-9384(71)90321-0

S. Stern and C. Alberini, Mechanisms of memory enhancement, Wiley Interdisciplinary Reviews: Systems Biology and Medicine, vol.33, issue.1, pp.37-53, 2013.
DOI : 10.1002/wsbm.1196

J. Sweeney, J. Kmiec, and D. Kupfer, Neuropsychologic impairments in bipolar and unipolar mood disorders on the CANTAB neurocognitive battery, Biological Psychiatry, vol.48, issue.7, pp.674-685, 2000.
DOI : 10.1016/S0006-3223(00)00910-0

M. Taylor and M. Fink, Melancholia: the diagnosis, pathophysiology and treatment of depressive illness, 2006.
DOI : 10.1017/CBO9780511544330

W. Taylor, D. Steffens, and M. Payne, Influence of serotonine transporter promoter region polymorphisms on hippocampal volumes in late-life depression. Archives of General Psychiatry, pp.537-544, 2005.

J. Thuile, C. Even, S. Friedman, and J. Guelfi, Inter-rater reliability of the French version of the core index for melancholia, Journal of Affective Disorders, vol.88, issue.2, pp.193-208, 2005.
DOI : 10.1016/j.jad.2005.07.004

N. Toni, Modifications morphologiques associées à la plasticité synaptique, Thèse de Sciences, mention biologique Thèse n° Sc. 3203, 2000.

C. Torrent, C. Del-mar-bonnin, and A. Martinez-aran, Efficacy of Functional Remediation in Bipolar Disorder: A Multicenter Randomized Controlled Study, American Journal of Psychiatry, vol.170, issue.8, pp.852-859, 2013.
DOI : 10.1176/appi.ajp.2012.12070971

I. Torres, V. Boudreau, and L. Yatham, Neuropsychological functioning in euthymic bipolar disorder: a meta-analysis, Acta Psychiatrica Scandinavica, vol.17, issue.s434
DOI : 10.1111/j.1399-5618.2004.00113.x

H. Van-praag, Exercise and the brain: something to chew on. Trends in neurosciences, pp.283-290, 2009.

E. Vermetten, M. Vythilingam, and S. Southwick, Long-term treatment with Paroxetine increases verbal declarative memory and hippocampal volume in posttraumatic stress disorder. Biological Psychiatry, pp.693-702, 2003.

P. Videbech and B. Ravnkilde, Hippocampal Volume and Depression: A Meta-Analysis of MRI Studies, American Journal of Psychiatry, vol.161, issue.11, pp.1957-66, 2004.
DOI : 10.1176/appi.ajp.161.11.1957

M. Vythilingam, E. Vermetten, and G. Anderson, Hippocampal volume, memory, and cortisol status in major depressive disorder: effects of treatment, Biological Psychiatry, vol.56, issue.2, 2004.
DOI : 10.1016/j.biopsych.2004.04.002

M. Zigmond, F. Bloom, and S. Landis, Fundamental neuroscience. Academic press, 1999.

X. Zhang, Z. Zhang, and W. Sha, Electroconvulsive therapy increases glial cell-line derived neurotrophic factor (GDNF) serum levels in patients with drug-resistant depression, Psychiatry Research, vol.170, issue.2-3, pp.273-275, 2009.
DOI : 10.1016/j.psychres.2009.01.011

X. Zhang, Z. Zhang, and C. Xie, Effect of treatment on serum glial cell line-derived neurotrophic factor in depressed patients, Progress in Neuro-Psychopharmacology and Biological Psychiatry, vol.32, issue.3, pp.886-890, 2008.
DOI : 10.1016/j.pnpbp.2008.01.004

X. Zhang, X. Li, and H. Zhang, Valproic acid as a promising agent to combat Alzheimer's disease, Brain Research Bulletin, vol.81, issue.1, pp.3-6, 2010.
DOI : 10.1016/j.brainresbull.2009.09.003

S. Zola-morgan and L. Squire, The primate hippocampal formation: evidence for a time-limited role in memory storage, Science, vol.250, issue.4978, pp.288-290, 1990.
DOI : 10.1126/science.2218534

K. Zou, W. Deng, and T. Li, Changes of Brain Morphometry in First-Episode, Drug-Na??ve, Non???Late-Life Adult Patients with Major Depression: An Optimized Voxel-Based Morphometry Study, Biological Psychiatry, vol.67, issue.2, pp.186-188, 2010.
DOI : 10.1016/j.biopsych.2009.09.014

A. Histoire, Note totale (Max=25) : ?? Histoire B rappel : Note totale (Max=25) : ?? Rappels mémoire logique 2 : Note totale, Max=50) : ?? Epreuve de reconnaissance Demander au patient de répondre par oui (O) ou non

A. Histoire, La femme s'appelait-elle Diane Boiron