Skip to Main content Skip to Navigation
Master Thesis

Électrorétinogramme multifocal et choriorétinopathie de Birdshot : à propos de 54 patients

Abstract : Birdshot chorioretinopathy is a chronic bilateral posterior uveitis associated in 90% with HLA-A29. Its diagnosis is often delayed. It requires many paraclinical exams to adjust treatment. Fullfield ERG has already shown its interest in the monitoring of birdshot chorioretinopathy. Multifocal electroretinogram, an objective technique provides an accurate mapping of the electrical activity of the outer retina. In our retrospective study of 54 right eyes with birdshot chorioretinopathy, according to the criteria of the International Classification, and comparable to the literature data, a specific pattern in multifocal ERG appears with a centrifugal distribution of the alteration in time of waves N1, P1, and N2 (ie a minimum reached in the center and a maximum reached in the periphery), associated with a centripetal distribution of the alteration in amplitude of waves N1, P1, and N2 (ie a maximum at the center and a minimal impairment in the periphery). We therefore demonstrated that 11 patients or 20.37% have a normal mf ERG, this pattern is found for the N1 wave: in 37.21% of patients for the amplitude, and in 53.49% of them for the implicit time; vs for the wave P1: in 50% of patients for the amplitude, and in 52.38% of them for the implicit time. Visual acuity does not fully reflect the severity of the disease. 14/54 patients has VA unchanged with abnormal multifocal electroretinogram. Multifocal ERG may allow earlier diagnosis of birdshot chorioretinopathy.
Document type :
Master Thesis
Complete list of metadata

Cited literature [113 references]  Display  Hide  Download

https://dumas.ccsd.cnrs.fr/dumas-01145031
Contributor : Université Paris Descartes - Scd <>
Submitted on : Thursday, April 23, 2015 - 1:57:19 PM
Last modification on : Friday, October 23, 2020 - 4:42:53 PM
Long-term archiving on: : Monday, September 14, 2015 - 12:46:11 PM

Identifiers

  • HAL Id : dumas-01145031, version 1

Citation

Juliette Knoeri. Électrorétinogramme multifocal et choriorétinopathie de Birdshot : à propos de 54 patients. Médecine humaine et pathologie. 2014. ⟨dumas-01145031⟩

Share

Metrics

Record views

380

Files downloads

1318