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Master Thesis

L'évaluation du bon usage du médicament en France : définitions, enjeux et méthodes en pharmaco-épidémiologie

Abstract : Recent healthcare controversies such as the “Mediator affair” and the concerns regarding third- and fourth-generation oral contraceptives have placed the appropriate use of medicines at the center of French healthcare issues. Despite the implementation of measures promoting appropriate drug use in recent years, certain barriers to optimal drug use remain. Recently, action plans have been established by each type of healthcare stakeholder with the goal of promoting the rational use of drugs. Such plans encompass new tools designed for healthcare professionals, keeping up-to-date databases, informational campaigns, and the use of innovative technology. Within the current regulatory framework, studies evaluating the appropriate use of drugs are increasingly important and required by and for health authorities and pharmaceutical companies. Based on their methodology, these studies enable the qualitative and quantitative evaluatio! n of the patient population treated by a drug or a drug class and/or their conditions of use as well as the identification of parameters leading to inappropriate drug use. These studies may include multiple data sources, none of which are completely exhaustive. In France, administrative healthcare claims databases are the most frequently employed, although they are not specifically designed for research purposes. Linking all available data sources regarding medicinal product use in France, including private databases and existing cohorts, would enable the optimization of this type of study. However, this type of measure is confronted with important legal constraints.
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Master Thesis
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Contributor : Bu Carreire Université de Bordeaux <>
Submitted on : Wednesday, May 20, 2015 - 4:38:21 PM
Last modification on : Thursday, May 30, 2019 - 5:32:00 PM
Long-term archiving on: : Thursday, April 20, 2017 - 5:31:30 AM


  • HAL Id : dumas-01153922, version 1



Bénédicte Sabin. L'évaluation du bon usage du médicament en France : définitions, enjeux et méthodes en pharmaco-épidémiologie. Sciences pharmaceutiques. 2015. ⟨dumas-01153922⟩



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