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Master Thesis

Cystite radique et oxygénothérapie hyperbare

Abstract : INTRODUCTION : Hemorrhagic radiation cystitis, crippling through its hematuria, occurs after 5 to 10% of pelvic radiotherapy. The first-line treatments are debilitating, HBO therapy would fit fighting against hypoxia. METHOD : A retrospective descriptive study was conducted in Bordeaux over a 6-year period between August 2008 and August 2014. The main objective of the study is to assess the immediate efficacy of HBOT on hemorrhagic radiation cystitis. The effectiveness has then been reassessed after 3 months and 12 months. RESULTS : Out of 33 patients, 74% have presented clinical improvements. This benefit was maintained in 78% of cases after 3 months and 67% after 12 months. A 56% efficacy has been measured at 3 months and 36% at 12 months. 85% of patients are men. 79% of hemorrhagic radiation cystitis follow radiotherapy of prostate cancer. Only 19% had mild complications of HBOT. CONCLUSION : HBOT is an effective treatment with a very good tolerance. Looking at it physiopathological rational, it would be beneficial to start it at an early stage of the persistent hematuria installation.
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Master Thesis
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Contributor : Bu Carreire Université de Bordeaux <>
Submitted on : Wednesday, May 27, 2015 - 6:44:13 PM
Last modification on : Wednesday, August 23, 2017 - 4:29:29 PM
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  • HAL Id : dumas-01157269, version 1



Valérie Spitz. Cystite radique et oxygénothérapie hyperbare. Médecine humaine et pathologie. 2015. ⟨dumas-01157269⟩



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