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Master Thesis

Recrudescence du nombre de cas de sérologies syphilitiques au cours de la grossesse sur l’île de la Réunion, étude sur 85 cas de 2003 à 2013

Abstract : Introduction: Syphilis is on the rise in France and in other developing countries, especially since the early 2000’s in the homosexual population. On Reunion Island, this increase is also affecting the heterosexual population and therefore women of childbearing age. Available data on positive syphilis serology in pregnant women is limited, especially from 2009. The main objective of this study was to determine the number of positive syphilitic serology in pregnant women during the period from 2003 to 2013 on Reunion Island. The secondary objective was to find predictors that can guide targeted serology. Method: Descriptive multicentric retrospective study on prevalence over a period of 10 years from the first of January 2003 to 31st of December 2013 in the four public hospitals in Reunion Island: the GHSR of St Pierre, the CHD of St Denis, the CHGM of St Paul and the GHSR of St Benoit. All women having been pregnant and TPHA and VDRL positive during this period were included. Results: 85 pregnancies were included in this study. The distribution according to the year is as follows: 2 cases in 2003 , no cases in 2004 , 1 case in 2005 and 2006 , 2 cases in 2007 , 10 cases in 2008 , 14 cases in 2009, 17 cases 2010, 15 cases in 2011 , 12 cases in 2012 and 11 cases in 2013. Discussion: This study confirms the data already known until 2008, and it indicates that the measures set up from 2010 had limited effectiveness. This study also finds predictors such as: co-infection with HCV, poor monitoring of pregnancy, isolated mother status, unfavorable socioeconomic conditions, contact with Madagascar, multiple partners and contact with prisons. These factors must be confirmed by a case-control or cohort.
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Master Thesis
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https://dumas.ccsd.cnrs.fr/dumas-01164646
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Submitted on : Wednesday, June 17, 2015 - 2:31:54 PM
Last modification on : Wednesday, August 23, 2017 - 4:32:02 PM
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Pierre Baranzelli. Recrudescence du nombre de cas de sérologies syphilitiques au cours de la grossesse sur l’île de la Réunion, étude sur 85 cas de 2003 à 2013. Médecine humaine et pathologie. 2015. ⟨dumas-01164646⟩

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