C. Dans-le-groupe and . Ouvert, on ne retrouvait pas de variation significative de la NIRS ou de la FTOE mais la NIRS tendait à diminuer à

. Dans-le-groupe-d, enfants nés à moins de 1000g (n=9), la FTOE baissait après la dose n°2 (H- 1 dose n°1 versus H+2 dose n°2 p=0.07 ; dose n°1 versus H+2 dose n°2 p=0.01

. Dans-le-groupe-d, enfants nés à 1000 g ou plus (n=5), la FTOE avait tendance à baisser après la dose n°1 (non significatif, p=0.06) et à monter après la dose 3 (non significatif, pp.0-06

. Soixante-pourcent, 10) avaient fermé leur canal. 40% (4/10) ont reçu une 2 ème cure d'ibuprofène dont cinquante%

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