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Master Thesis

Problèmes posés par la consommation des benzodiazépines chez les personnes âgées : focus sur la mémoire

Abstract : By a French population increasingly aging, consumption of benzodiazepines has become a major public health problem. On January 1, 2015, the class of 65 and over is more than 12.3 million of the 66 million inhabitants of the France. In addition, 11.5 million French have used at least one benzodiazepine and about 20% of the 12 million people chronically consume hypnotics or anxiolytics. Normal physiological conditions of age make them naturally more vulnerable to the risks associated with the use of these molecules. Thus, falls, car accidents and cognitive impairment are frequently encountered cases. Indeed, the use of benzodiazepines in the elderly has a significant impact on memory functioning. Several biochemical mechanisms involved but all types and stages of memory does not seem to be affected in the same way. In addition, recent studies show a probable link between the consumption of benzodiazepines and Alzheimer's disease but should remain cautious on data obtained because no certainty has been established. Finally, because of the importance of consumption in France, significant adverse effects they generate and certain problematic use, benzodiazepines are the subject for many years, of a special attention of health authorities, particularly the ANSM.
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Master Thesis
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Contributor : Bu Carreire Université de Bordeaux <>
Submitted on : Wednesday, July 22, 2015 - 4:49:33 PM
Last modification on : Wednesday, April 1, 2020 - 4:58:04 PM
Long-term archiving on: : Friday, October 23, 2015 - 11:21:49 AM


  • HAL Id : dumas-01179524, version 1



Marie Leroy. Problèmes posés par la consommation des benzodiazépines chez les personnes âgées : focus sur la mémoire. Sciences pharmaceutiques. 2015. ⟨dumas-01179524⟩



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