L. Rôles-thérapeutiques-des-polyphénols-en-santé-humaine and .. , 93 3.2-1. Propriétés anti-fongiques, anti-bactériennes et anti-virales, p.93

H. Bennani, J. Fiet, and A. Adlouni, Impact de l'huile d'argan sur le cancer de la prostate : étude de l'e et an proliféra f des polyphénols, pp.23-26, 2009.

P. Bernanose, Maladie d'Alzheimer : ApoE4, le variant qui s'attaque u système vasculaire cérébral, Nature, 2012.

J. Birks, Cholinesterase inhibitors for Alzheimer's disease, Cochrane Database Syst Rev, vol.11, issue.suppl 2, p.5593, 2006.
DOI : 10.1002/14651858.CD005593

C. Boubekri, Etude de l'activité antioxydante des polyphénols extraits de Solanum melongena par des techniques électrochimiques, Thèse de Doctorat à l, 2014.

M. A. Bouzid, Exercice physique, marqueurs antioxydants et peroxydation lipidique : effet de l'âge et du niveau d'aptitude physique, Thèse de doctorat en Sciences et Technologies des Activités Physiques et Sportives, pp.8-34, 2014.

J. Broustet, Wine and health, Heart, vol.81, issue.5, pp.459-460, 1999.
DOI : 10.1136/hrt.81.5.459

. Bush-al, The metallobiology of Alzheimer's disease, Trends in Neurosciences, vol.26, issue.4, pp.207-214, 2003.
DOI : 10.1016/S0166-2236(03)00067-5

A. Bush, C. Masters, and R. Et-tanzi, Copper, ??-amyloid, and Alzheimer's disease: Tapping a sensitive connection, Proceedings of the National Academy of Sciences, vol.100, issue.20, pp.11193-11194, 2003.
DOI : 10.1073/pnas.2135061100

I. Ceballos-picot, A. Nicole, M. Clement, J. Bourre, and P. Sinet, Age-related changes in antioxidant enzymes and lipid peroxidation in brains of control and transgenic mice overexpressing copper-zinc superoxide dismutase, Mutation Research/DNAging, vol.275, issue.3-6, pp.281-293, 1992.
DOI : 10.1016/0921-8734(92)90032-K

Z. Chen and C. Et-zhong, Decoding Alzheimer's disease from perturbed cerebral glucose metabolism: Implications for diagnostic and therapeutic strategies, Progress in Neurobiology, vol.108, pp.21-43, 2013.
DOI : 10.1016/j.pneurobio.2013.06.004

K. Chira, J. H. Suh, C. Saucier, and P. L. Teissèdre, Grape phenolics, Les polyphénols du raisin, pp.75-82, 2008.
DOI : 10.1007/s10298-008-0293-3

A. Choi and J. Et-alam, Heme oxygenase-1: function, regulation, and implication of a novel stress-inducible protein in oxidant-induced lung injury., American Journal of Respiratory Cell and Molecular Biology, vol.15, issue.1, pp.9-19, 1996.
DOI : 10.1165/ajrcmb.15.1.8679227

Y. Christen, Oxidative stress and Alzheimer disease, The American Journal of Clinical Nutrition, vol.71, pp.621-630, 2000.

C. S. Et-crouzet and J. , Polyphénols et procédés, Lavoisier édition TEC&DOC, pp.5-276, 2011.

D. Commenges, V. Scotet, S. Renaud, H. Jacqmin-gadda, P. Barberger-gateau et al., Intake of flavonoids and risk of dementia, European Journal of Epidemiology, vol.16, issue.4, pp.357-363, 2000.
DOI : 10.1023/A:1007614613771

G. Coudin, Les familles de malades atteints de maladie d'Alzheimer et leur r??ticence par rapport ?? l'aide professionnelle (Commentaire), Sciences sociales et sant??, vol.23, issue.3, 2005.
DOI : 10.3406/sosan.2005.1661

A. Daccache, Etude du mécanisme d'agrégation de la protéine TAU et son inhibition par des composes phénoliques, Thèse de doctorat en molécules et matières condensées, 2011.

A. Damianaki, E. Bakogeorgou, M. Kampa, G. Notas, A. Hatzoglou et al., Potent inhibitory action of red wine polyphenols on human breast cancer cells, Journal of Cellular Biochemistry, vol.52, issue.3, pp.429-470, 2000.
DOI : 10.1002/1097-4644(20000901)78:3<429::AID-JCB8>3.0.CO;2-M

J. Delattre, J. L. Beaudeux, and D. Et-bonnefort-rousselot, Radicaux libres et Stress oxydant, 2005.

E. D. De-robertis and E. M. Et-de-robertis, Biologie cellulaire et moléculaire, p.287, 1983.

J. Desport and P. Et-couratier, Stress oxydant et maladies neurod??g??n??ratives, Nutrition Clinique et M??tabolisme, vol.16, issue.4, pp.253-260, 2002.
DOI : 10.1016/S0985-0562(02)00172-3

J. Drake, C. Link, and D. Butterfield, Oxidative stress precedes fibrillar deposition of Alzheimer's disease amyloid ??-peptide (1???42) in a transgenic Caenorhabditis elegans model, Neurobiology of Aging, vol.24, issue.3, pp.415-420, 2003.
DOI : 10.1016/S0197-4580(02)00225-7

S. Donnou, Caractérisation des cellules microgliales adultes et de leur potentiel en immunothérapie des tumeurs cérébrales, Thèse de doctorat Immunologie. Université d'Angers, pp.11-39, 2007.

C. Duyckaerts, B. Delatour, and M. Et-potier, Classification and basic pathology of Alzheimer disease, Acta Neuropathologica, vol.14, issue.2, 2009.
DOI : 10.1007/s00401-009-0532-1

E. Darra and N. , Les composés phénoliques des raisins : étude du potentiel qualitatif et des procédés émergeants d'extraction, Thèse de doctorat, 2013.

R. Fabre, Cholestérol et maladies cardiovasculaires : intérêt des molécules d'origine naturelle, Thèse d'exercice, 2010.

O. Fain, Mise au point : Carences en vitamine C. La revue de médecine interne, pp.872-880, 2004.

M. Folstein, S. Folstein, and P. Et-mchugh, ???Mini-mental state???, Journal of Psychiatric Research, vol.12, issue.3, pp.189-198, 1975.
DOI : 10.1016/0022-3956(75)90026-6

C. Gallez, Rapport sur la maladie d'Alzheimer, 2005.

M. Gardes-albert, D. Bonnefont-rousselot, Z. Abedinzadeh, and D. Et-jore, Espèces réactives de l'oxygène, Comment l'oxygène peut-il devenir toxique ? . L'actualité chimique, pp.91-96, 2003.

M. Gatz, C. Reynolds, L. Fratiglioni, B. Johansson, J. Mortimer et al., Role of Genes and Environments for Explaining Alzheimer Disease, Archives of General Psychiatry, vol.63, issue.2, 2006.
DOI : 10.1001/archpsyc.63.2.168

J. B. Gayraud, Le vin et les effets bénéfiques de ses polyphénols sur la santé de l'Homme, 2011.

K. Ghedira, Effets bénéfiques des métabolites secondaires (alcool et polyphénols) du vin rouge, pp.37-41, 2003.

K. Ghedira, Flavonoids: structure, biological activities, prophylactic function and therapeutic uses, Phytotherapie, vol.3, issue.4, pp.162-169, 2005.
DOI : 10.1007/s10298-005-0096-8

M. Gueroux, La maladie d'Alzheimer et la place des polyphénols au sein des nouvelles stratégies thérapeutiques : analyse multi-techniques des interactions « polyphénols-peptides tau, Thèse de doctorat, 2013.

S. Hadi, S. Bhat, A. Azmi, S. Hanif, U. Shamim et al., Oxidative breakage of cellular DNA by plant polyphenols : a putative mechanism for anticancer properties. Seminars in Cancer Biology, pp.370-376, 2007.

. Haute-autorité-de-santé-publique, Recommandation de bonnes pratiques : maladie d'Alzheimer et maladies apparentées, 2011.

M. Hertog, E. Feskens, P. Hollman, M. Katan, and D. Et-kromhout, Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study, The Lancet, vol.342, issue.8878, pp.1007-1018, 1993.
DOI : 10.1016/0140-6736(93)92876-U

L. Ho, L. H. Chen, J. Wang, W. Zhao, S. Talcott et al., Heterogeneity in Red Wine Polyphenolic Contents Differentially Influences Alzheimer's Disease-type Neuropathology and Cognitive Deterioration, J Alzheimers Dis, vol.16, issue.1, pp.59-72, 2009.

C. Hureau, 2012) ions métalliques, cascade amyloïde et maladie d'Alzheimer, CNRS

K. Ishige, D. Schubert, and Y. Et-sagara, Flavonoids protect neuronal cells from oxidative stress by three distinct mechanisms, Free Radical Biology and Medicine, vol.30, issue.4, pp.433-446, 2001.
DOI : 10.1016/S0891-5849(00)00498-6

M. H. Jang, X. L. Piao, H. Y. Kim, E. Cho, S. Baek et al., Resveratrol oligomers from Vitisamurensis attenuate beta-amyloid-induced oxidative stress in PC12 cells, Biol Pharm Bull, issue.6, pp.301130-1134, 2007.

J. Jang and Y. Et-surh, Protective effect of resveratrol on ??-amyloid-induced oxidative PC12 cell death, Free Radical Biology and Medicine, vol.34, issue.8, pp.1100-1110, 2003.
DOI : 10.1016/S0891-5849(03)00062-5

E. Janle, T. Chen, J. Kritchevsky, K. Hargett, K. Feller et al., Pharmacokinetics and brain distribution of polyphenols from fruit extract in young pigs, The FASEB Journal, p.28, 2014.

S. Karuppagounder, J. Pinto, H. Xu, L. Chen, M. Beal et al., Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease, Neurochemistry International, vol.54, issue.2, 2008.
DOI : 10.1016/j.neuint.2008.10.008

J. Keevil, H. Osman, J. Reed, and J. Et-folts, Grape juice, but not orange juice or grapefruit juice, inhibits human platelet aggregation, J Nutr, vol.130, pp.53-59, 2000.

M. Kessler, G. Ubeau, and L. Et-jung, Anti-and pro-oxydant activity of rutine and quercetin derivated, J. Pharm. Pharmacol, vol.55, pp.1-11, 2002.

D. Kim, SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis, The EMBO Journal, vol.81, issue.13, p.13, 2007.
DOI : 10.1038/sj.emboj.7601758

M. Kivipelto, E. Helkala, M. Laakso, T. Hanninen, M. Hallikainen et al., Midlife vascular risk factors and Alzheimer's disease in later life: longitudinal, population based study, BMJ, vol.322, issue.7300, pp.1447-1451, 2001.
DOI : 10.1136/bmj.322.7300.1447

M. Kivipelto, M. P. Laakso, J. Tuomilehto, A. Nissinen, and H. Et-soininen, Hypertension and Hypercholesterolaemia as Risk Factors for Alzheimer??s Disease, CNS Drugs, vol.903, issue.7, pp.435-479, 2002.
DOI : 10.2165/00023210-200216070-00001

M. Kivipelto, T. Ngandu, L. Fratiglioni, M. Viitanen, I. Kareholt et al., Obesity and Vascular Risk Factors at Midlife and the Risk of Dementia and Alzheimer Disease, Archives of Neurology, vol.62, issue.10, pp.1556-60, 2005.
DOI : 10.1001/archneur.62.10.1556

W. Li, X. Zhang, Y. Wu, and X. Et-tian, Anti-inflammatory effect and mechanism of proanthocyanidins from grape seeds, Acta.Pharmacol.Sin, vol.22, issue.12, pp.1117-1120, 2001.

B. Liu, H. Gao, J. Wang, G. Jeohn, and C. Cooper, Role of Nitric Oxide in Inflammation-Mediated Neurodegeneration, Annals of the New York Academy of Sciences, vol.89, issue.1, pp.318-331, 2002.
DOI : 10.1111/j.1749-6632.2002.tb04077.x

A. Lobo, L. Launer, L. Fratiglioni, K. Andersen, D. Carlo et al., Prevalence of dementias and major Subtypes in Europe: a collaboration study of population-based cohorts, Neurology, vol.54, pp.114-123, 2000.

M. Lock, La « molécularisation » de l'esprit et la recherche sur la démence naissante, Sciences Sociales et Santé, vol.24, p.1, 2006.

W. Markesbery and M. Lovell, Four-Hydroxynonenal, a Product of Lipid Peroxidation, is Increased in the Brain in Alzheimer???s Disease, Neurobiology of Aging, vol.19, issue.1, pp.33-36, 1998.
DOI : 10.1016/S0197-4580(98)00009-8

F. Massoud, La maladie d'Alzheimer mise à jour en 200, Le Médecin du Québec, vol.44, p.4

F. Mazue, Effet des polyphénols de vin rouge sur la prolifération cellulaire et sur le métabolisme du resvératrol, 2011.

P. Mecocci, U. Macgarvey, and F. Et-beal, Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease, Annals of Neurology, vol.90, issue.5, pp.747-51, 1994.
DOI : 10.1002/ana.410360510

P. Mecocci, M. Polidori, A. Cherubini, T. Ingegni, P. Mattioli et al., Lymphocyte Oxidative DNA Damage and Plasma Antioxidants in Alzheimer Disease, Archives of Neurology, vol.59, issue.5, pp.794-802, 2002.
DOI : 10.1001/archneur.59.5.794

J. M. Merillon, H. Temsamami, J. Delaunay, and S. Et-krisa, Stilbènes : de la chimie à la neuroprotection. Cahiers de Nutrition et de Diététique, pp.173-180, 2014.

H. Milane, La quercétine et ses dérivés : molécules à caractère prooxydant ou capteurs de radicaux libres ; études et applications thérapeutiques, Thèse de doctorat de l'université de Louis Pasteur, pp.13-36, 2004.

Z. Mohammedi, Etude du pouvoir antimicrobien et antioxydant des huiles essentielles et flavonoïdes de quelques plantes de la région de Tlemecen, 2006.

J. Morelle, L'oxydation des aliments et la santé, 2003.

E. Morelle-lauzanne and P. , Diet and oxidative stress: sources of lipoperoxidation and the means to protect against it, Phytoth??rapie, vol.43, issue.3-4, 2006.
DOI : 10.1007/s10298-006-0196-0

I. Mucsi and B. Et-pragai, Inhibition of virus multiplication and alteration of cyclic AMP level in cell cultures by flavonoids, Experientia, vol.56, issue.7, pp.930-931, 1985.
DOI : 10.1007/BF01970018

R. M. Murphy, Kinetics of amyloid formation and membrane interaction with amyloidogenic proteins, Biochimica et Biophysica Acta (BBA) - Biomembranes, vol.1768, issue.8, pp.1923-1934, 2007.
DOI : 10.1016/j.bbamem.2006.12.014

I. Myara, C. Alamowitch, O. Michel, D. Heudes, J. Bariety et al., Lipoprotein Oxidation and Plasma Vitamin E in Nondiabetic Normotensive Obese Patients, Obesity Research, vol.17, issue.1, pp.112-120, 2003.
DOI : 10.1038/oby.2003.19

K. A. Naidu, Vitamin C in Human Health and Disease is Still a Mystery? An Overview, Nutrition Journal, vol.2, issue.7, pp.1-10, 2003.
DOI : 10.1201/b16307-8

M. Netzel, G. Strass, I. Bitsch, R. Könitz, M. Christmann et al., Effect of grape processing on selected antioxidant phenolics in red wine, Journal of Food Engineering, vol.56, issue.2-3, pp.223-231, 2003.
DOI : 10.1016/S0260-8774(02)00256-X

F. Nicks, Y. Borguet, S. Delfosse, D. Bicchielli, L. Delaude et al., Microwave-assisted Ruthenium-Catalysed Reactions, Introduction générale, Aust. J, 2009.

E. Nkhili, Polyphénols de l'alimentation : extraction, interactions avec les ions du fer et du cuivre, oxydation et pouvoir antioxydant, Thèse doctorat, 2009.

S. Olusi, Obesity is an independent risk factor for plasma lipid peroxidation and depletion of erythrocyte cytoprotectic enzymes in humans, International Journal of Obesity, vol.26, issue.9, pp.1159-1164, 2002.
DOI : 10.1038/sj.ijo.0802066

K. Ono, Y. Yoshiike, A. Takashima, K. Hasegawa, H. Naiki et al., Potent anti-amyloidogenic and fibril-destabilizing effects of polyphenols in vitro: implications for the prevention and therapeutics of Alzheimer's disease, Journal of Neurochemistry, vol.49, issue.1, pp.172-81, 2003.
DOI : 10.1046/j.1471-4159.2003.01976.x

J. M. Orgogozo, Facteurs de risque vasculaire et risque de maladie d'Alzheimer : revue d'études épidémiologiques, 2006.

M. Pera, D. Alcolea, R. Sanchez-valle, C. Guardia-laguarta, M. Colom-cadena et al., Distinct patterns of APP processing in the CNS in autosomal-dominant and sporadic Alzheimer disease, Acta Neuropathologica, vol.64, issue.6, pp.201-213, 2013.
DOI : 10.1007/s00401-012-1062-9

M. A. Piquet and X. Et-hébuterne, Nutrition en pathologie digestive, p.93, 2007.

E. Apolipoprotein, Alzheimer's disease, Lancet, vol.342, pp.170-174

J. Poirier, Apolipoprotein E in animal models of CNS injury and in alzheimer's disease, Trends in Neurosciences, vol.17, issue.12, pp.525-555, 1994.
DOI : 10.1016/0166-2236(94)90156-2

R. Prior, Fruits and Vegetables in the prevention of cellular oxidative damage, Am J Clin Nutr, vol.78, pp.570-579, 2003.

T. Rissanen, S. Voutilainen, J. Virtanen, B. Venho, M. Vanharanta et al., Low intakes of fruits, berries, and vegetables are associated with excess mortality in men : The Kuopio Ischaemic Heart Diseases riesk factor (KIHD) Study, J Nutr, vol.133, pp.199-204, 2003.

C. Rivière, Interactions Polyphénols/ ?-Amyloïde : Impact dans la maladie d'Alzheimer, Thèse de doctorat, 2008.

A. Roussel and M. Ferry, Stress oxydant, nutrition et vieillissement, Nutr Biochem, vol.13, pp.75-79, 2002.

A. Sabiha, Polyphénols de l'alimentation : extraction, pouvoir antioxydant et interaction avec des ions métalliques, Thèse de doctorat, 2013.

L. Saïd, F. Tamion, A. Leplingard, A. Leplingard, C. Beaumont et al., Rôles protecteurs de l'hème oxygénase et des catabolites de l'hème, Hématologie, vol.13, issue.4, pp.251-65, 2007.

S. Schaffer and B. Et-halliwell, Do polyphenols enter the brain and does it matter? Some theoretical and practical considerations, Genes & Nutrition, vol.9, issue.Suppl 1, pp.99-109, 2011.
DOI : 10.1007/s12263-011-0255-5

J. Sevalle, Etude de la production et de la dégradation du peptide amyloïde dans la maladie d'Alzheimer, 2009.

. Smith, Oxidative damage in Alzheimer's, Nature, vol.382, issue.6587, pp.120-121, 1996.
DOI : 10.1038/382120b0

M. Soderberg, C. Edlund, K. Kristensson, and G. Et-dallner, Lipid Composition in Different Regions of the Brain in Alzheimer's Disease/Senile Dementia of Alzheimer's Type, Journal of Neurochemistry, vol.27, issue.5, pp.1646-1653, 1992.
DOI : 10.1111/j.1471-4159.1992.tb10994.x

G. Spedding, A. Ratty, and E. J. Et-middleton, Inhibition of reverse transcriptases by flavonoids, Antiviral Research, vol.12, issue.2, pp.99-110, 1989.
DOI : 10.1016/0166-3542(89)90073-9

N. Stabbert, complexation of condensed tannins with metal ions in plant polyphenols. Synthesis, properties, significance, pp.421-436, 1992.

R. Stocker, Y. Yamamoto, A. F. Mcdonagh, A. N. Glazer, and . Ames, Bilirubin is an antioxidant of possible physiological importance, Science, vol.235, issue.4792, pp.1043-1046, 1987.
DOI : 10.1126/science.3029864

W. Strittmatter, A. Saunders, D. Schmechel, M. Pericak-vance, J. Enghild et al., Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease., Proceedings of the National Academy of Sciences, vol.90, issue.5, pp.1977-81, 1993.
DOI : 10.1073/pnas.90.5.1977

K. Subbarao and J. Richardson, Autopsy Samples of Alzheimer's Cortex Show Increased Peroxidation In Vitro, Journal of Neurochemistry, vol.4, issue.1, pp.342-345, 1990.
DOI : 10.1002/ana.410220208

Y. Suh and F. Et-checler, Amyloid Precursor Protein, Presenilins, and alpha -Synuclein: Molecular Pathogenesis and Pharmacological Applications in Alzheimer's Disease, Pharmacological Reviews, vol.54, issue.3, pp.469-525, 2002.
DOI : 10.1124/pr.54.3.469

L. Svennerholm and C. Et-gottfries, Membrane Lipids, Selectively Diminished in Alzheimer Brains, Suggest Synapse Loss as a Primary Event in Early-Onset Form (Type I) and Demyelination in Late-Onset Form (Type II), Journal of Neurochemistry, vol.13, issue.Suppl., pp.1039-1047, 1994.
DOI : 10.1046/j.1471-4159.1994.62031039.x

P. Taillandier, Le vin : composition et transformations chimiques, 2005.

P. Teissèdre and N. Et-landrault, Wine phenolics: contribution to dietary intake and bioavailability, Food Research International, vol.33, issue.6, pp.461-468, 2000.
DOI : 10.1016/S0963-9969(00)00070-3

J. P. Tilement, J. J. Hauw, and V. Et-papadopoulos, Le défi de la maladie d'Alzheimer Synergies franco-québéquoises, 2012.

J. P. Tillement, J. J. Hauw, and V. Et-papadopoulos, Vieillissement et démences : Un défi médical, scientifique et socio économique, Lavoisier médecine sciences édition, 2014.

E. Vandelle, B. Poinssot, D. Wendehenne, M. Bentéjac, and A. Et-pugin, Integrated Signaling Network Involving Calcium, Nitric Oxide, and Active Oxygen Species but Not Mitogen-Activated Protein Kinases in BcPG1-Elicited Grapevine Defenses, Molecular Plant-Microbe Interactions, vol.19, issue.4, pp.429-440, 2006.
DOI : 10.1094/MPMI-19-0429

T. Vanderweyde, M. Bednar, S. Forman, and B. Et-wolozin, Iatrogenic risk factors for Alzheimer's disease : surgery and anesthesia, J Alzheimer Dis, vol.111, pp.964-970, 2010.

X. Vitrac, A. Bornet, R. Vanderlinde, A. Bornet, J. Valls et al., -resveratrol, ??-viniferin) in Brazilian Wines, Journal of Agricultural and Food Chemistry, vol.53, issue.14, pp.5664-5669, 2005.
DOI : 10.1021/jf050122g

URL : https://hal.archives-ouvertes.fr/hal-00655835

H. Wang, M. Zhao, B. Yang, Y. Jiang, and G. Et-rao, Identification of polyphénols in tobacco leaf and their antioxydant and antimicrobial activities. Food chemistry, pp.1399-1406, 2008.

J. Wang, L. Ho, Z. Zhao, I. Seror, N. Humala et al., Moderate consumption of Cabernet Sauvignon attenuates A?? neuropathology in a mouse model of Alzheimer's disease, The FASEB Journal, vol.20, issue.13, pp.2313-2320, 2006.
DOI : 10.1096/fj.06-6281com

J. Wang, L. Ho, and W. Z. , Grape-Derived Polyphenolics Prevent A?? Oligomerization and Attenuate Cognitive Deterioration in a Mouse Model of Alzheimer's Disease, Journal of Neuroscience, vol.28, issue.25, pp.6388-6392, 2008.
DOI : 10.1523/JNEUROSCI.0364-08.2008

X. Wang and P. Et-quinn, The structure and phase behaviour of ??-tocopherol-rich domains in 1-palmitoyl-2-oleoyl-phosphatidylethanolamine, Biochimie, vol.88, issue.12, pp.1883-1901, 2006.
DOI : 10.1016/j.biochi.2006.07.017

A. Waterhouse and P. Et-teissèdre, Levels of phenolics in california varietal wines Livre : " Wine: nutritional and therapeutic benefits, pp.11-23, 1997.

H. Weiner and D. Et-frenkel, Immunology and immunotherapy of Alzheimer's disease, Nature Reviews Immunology, vol.6, issue.6, 2006.
DOI : 10.1038/nri1881

S. Weyerer, M. Scaufele, B. Wiese, W. Maier, F. Tebarth et al., Current alcohol consumption and its relationship to incident dementia: results from a 3-year follow-up study among primary care attenders aged 75 years and older, Age and Ageing, vol.40, issue.4, pp.456-63, 2011.
DOI : 10.1093/ageing/afr007

M. P. Williamso, T. G. Mccrmick, C. L. Nance, and W. T. Et-shearer, Epigallocatechin gallate, the main polyphenol in green tea, binds to the T-cell receptor, CD4: Potential for HIV-1 therapy, Journal of Allergy and Clinical Immunology, vol.118, issue.6, pp.1369-1374, 2006.
DOI : 10.1016/j.jaci.2006.08.016

Y. Cs, Inhibition of carconigenesis by dietary polyphenlic compounds, Annu Rev Nutr, vol.21, pp.381-406, 2001.

F. Zhang, J. Liu, and J. Shi, Anti-inflammatory activities of resveratrol in the brain: Role of resveratrol in microglial activation, European Journal of Pharmacology, vol.636, issue.1-3, pp.1-7, 2010.
DOI : 10.1016/j.ejphar.2010.03.043