ETFAD/EADV eczema task force 2009 position paper on diagnosis and treatment of atopic dermatitis, Journal of the European Academy of Dermatology and Venereology, vol.142, issue.Suppl., pp.317-345, 2010. ,
DOI : 10.1111/j.1468-3083.2009.03415.x
Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis, Nature Genetics, vol.48, issue.4, pp.441-447, 2006. ,
DOI : 10.1038/ng1767
Psychiatric comorbidity in adult eczema, British Journal of Dermatology, vol.15, issue.Suppl., pp.878-83, 2009. ,
DOI : 10.1111/j.1365-2133.2009.09309.x
Atopic Dermatitis Burden Scale for Adults: Development and Validation of a New Assessment Tool, Acta Dermato Venereologica, vol.95, issue.6, 2014. ,
DOI : 10.2340/00015555-1945
A randomized trial of methotrexate versus azathioprine for severe atopic eczema, Journal of Allergy and Clinical Immunology, vol.128, issue.2, pp.353-362, 2011. ,
DOI : 10.1016/j.jaci.2011.03.024
Ten years experience with oral immunosuppressive treatment in adult patients with atopic dermatitis in two academic centres, Journal of the European Academy of Dermatology and Venereology, vol.169, issue.10, 2009. ,
DOI : 10.1111/jdv.13064
Diagnostic features of atopic dermatitis, ActaDerm VenereolStockh), vol.92, pp.44-51, 1980. ,
Using the Physician Global Assessment in a Clinical Setting to Measure and Track Patient Outcomes, JAMA Dermatology, vol.151, issue.4, 2014. ,
DOI : 10.1001/jamadermatol.2014.3513
Anti-IL-5 recombinant humanized monoclonal antibody (Mepolizumab) for the treatment of atopic dermatitis, Allergy, vol.159, issue.5, pp.693-699, 2005. ,
DOI : 10.1164/rccm.2304001
Cyclosporin greatly improves the quality of life of adults with severe atopic dermatitis. A randomized, double-blind, placebo-controlled trial, British Journal of Dermatology, vol.19, issue.4, pp.422-452, 1993. ,
DOI : 10.1111/j.1365-2230.1987.tb01844.x
Cyclosporin in atopic dermatitis: a multicentre placebo-controlled study, British Journal of Dermatology, vol.129, issue.5, pp.634-674, 1994. ,
DOI : 10.1016/S0140-6736(89)92941-3
Azathioprine in severe adult atopic dermatitis: a double-blind, placebo-controlled, crossover trial, British Journal of Dermatology, vol.88, issue.2, pp.324-354, 2002. ,
DOI : 10.1001/archderm.131.2.193
Azathioprine dosed by thiopurine methyltransferase activity for moderate-to-severe atopic eczema: a double-blind, randomised controlled trial, The Lancet, vol.367, issue.9513, pp.839-885, 2006. ,
DOI : 10.1016/S0140-6736(06)68340-2
An open-label, dose-ranging study of methotrexate for moderate-to-severe adult atopic eczema, British Journal of Dermatology, vol.16, issue.2, 2007. ,
DOI : 10.1111/j.1365-2133.2005.06592.x
Low-dose methotrexate treatment for moderate-to-severe atopic dermatitis in adults, Journal of the European Academy of Dermatology and Venereology, vol.120, issue.6, pp.43-52, 2010. ,
DOI : 10.1111/j.1468-3083.2009.03351.x
Methotrexate versus cyclosporine in the treatment of severe atopic dermatitis in children: a multicenter experience from Egypt, European Journal of Pediatrics, vol.135, issue.3, pp.351-357, 2013. ,
DOI : 10.1007/s00431-012-1893-3
Drug combinations with methotrexate to treat rheumatoid arthritis, Clin Exp Rheumatol, vol.28, issue.5, pp.52-59, 2010. ,
Prednisolone vs. ciclosporin for severe adult eczema. An investigator-initiated double-blind placebo-controlled multicentre trial, British Journal of Dermatology, vol.143, issue.Suppl. 62, pp.661-669, 2010. ,
DOI : 10.1111/j.1365-2133.2009.09561.x
Enteric-coated mycophenolate sodium versus cyclosporin A??as long-term treatment in adult patients with severe atopic dermatitis: A??randomized controlled trial, Journal of the American Academy of Dermatology, vol.64, issue.6, pp.1074-84, 2011. ,
DOI : 10.1016/j.jaad.2010.04.027
Predisposing factors and clinical features of eczema herpeticum: a retrospective analysis of 100 cases, Journal of the American Academy of Dermatology, vol.49, issue.2, pp.198-205, 2003. ,
DOI : 10.1067/S0190-9622(03)00896-X
Biologics in atopic dermatitis, JDDG: Journal der Deutschen Dermatologischen Gesellschaft, vol.64, issue.7, pp.174-182, 2012. ,
DOI : 10.1111/j.1610-0387.2011.07760.x
ETFAD/EADV eczema task force 2009 position paper on diagnosis and treatment of atopic dermatitis, Journal of the European Academy of Dermatology and Venereology, vol.142, issue.Suppl., pp.317-345, 2010. ,
DOI : 10.1111/j.1468-3083.2009.03415.x
Diagnostic features of atopic dermatitis, ActaDerm VenereolStockh), vol.92, pp.44-51, 1980. ,
The U.K. Working Party's Diagnostic Criteria for Atopic Dermatitis.., British Journal of Dermatology, vol.131, issue.3, pp.383-96, 1994. ,
DOI : 10.1016/0895-4356(90)90122-6
URL : https://hal.archives-ouvertes.fr/in2p3-00008652
Psychiatric comorbidity in adult eczema, British Journal of Dermatology, vol.15, issue.Suppl., pp.878-83, 2009. ,
DOI : 10.1111/j.1365-2133.2009.09309.x
Skin colonization by Staphylococcus aureus in patients with eczema and atopic dermatitis and relevant combined topical therapy: a double-blind multicentre randomized controlled trial, British Journal of Dermatology, vol.61, issue.4, pp.680-687, 2006. ,
DOI : 10.1111/j.1365-2133.1974.tb06447.x
Pathogenesis of atopic dermatitis, Clinical & Experimental Allergy, vol.192, issue.3, pp.566-74 ,
DOI : 10.1111/all.12526
Genetics of atopic dermatitis, JDDG: Journal der Deutschen Dermatologischen Gesellschaft, vol.162, issue.1 Pt 1, pp.670-676, 2011. ,
DOI : 10.1111/j.1610-0387.2011.07656.x
Immunology of atopic eczema: overcoming the Th1/Th2 paradigm, Allergy, vol.56, issue.2 Pt 1, pp.974-82, 2013. ,
DOI : 10.1111/all.12184
Association of CARD15 polymorphisms with atopy-related traits in a population-based cohort of Caucasian adults, Clinical <html_ent glyph="@amp;" ascii="&"/> Experimental Allergy, vol.9, issue.7, pp.866-72, 2005. ,
DOI : 10.1016/S1074-7613(01)00176-5
The Toll-like receptor 2 R753Q polymorphism defines a subgroup of patients with atopic dermatitis having severe phenotype, Journal of Allergy and Clinical Immunology, vol.113, issue.3, pp.565-572, 2004. ,
DOI : 10.1016/j.jaci.2003.12.583
Putative association of a TLR9 promoter polymorphism with atopic eczema, Allergy, vol.7, issue.2 Suppl., pp.766-72, 2007. ,
DOI : 10.1111/j.1398-9995.2007.01358.x
Dichotomic Nature of Atopic Dermatitis Reflected by Combined Analysis of Monocyte Immunophenotyping and Single Nucleotide Polymorphisms of the Interleukin-4/Interleukin-13 Receptor Gene: The Dichotomy of Extrinsic and Intrinsic Atopic Dermatitis, Journal of Investigative Dermatology, vol.119, issue.4, pp.870-875, 2002. ,
DOI : 10.1046/j.1523-1747.2002.00191.x
Genetic variants of the IL13 and IL4 genes and atopic diseases in at-risk children, Genes and Immunity, vol.4, issue.5, 2003. ,
DOI : 10.1038/sj.gene.6363985
Association of a STAT 6 haplotype with elevated serum IgE levels in a population based cohort of white adults, Journal of Medical Genetics, vol.41, issue.9, pp.658-63, 2004. ,
DOI : 10.1136/jmg.2004.020263
Genome-Wide Scan on Total Serum IgE Levels Identifies FCER1A as Novel Susceptibility Locus, PLoS Genetics, vol.30, issue.8, 2008. ,
DOI : 10.1371/journal.pgen.1000166.s014
-Methyltransferase C314T (Thr105Ile) Polymorphism with Atopic Dermatitis in Caucasian Children, Pharmacotherapy, vol.68, issue.12, pp.1495-501, 2008. ,
DOI : 10.1186/1471-2350-9-15
URL : https://hal.archives-ouvertes.fr/inserm-00409448
Polymorphisms in human histamine receptor H4 gene are associated with atopic dermatitis, British Journal of Dermatology, vol.6, issue.Suppl, pp.1038-1081, 2010. ,
DOI : 10.1111/j.1365-2133.2010.09675.x
Mast cells and basophils in cutaneous immune responses, Allergy, vol.192, issue.34 Suppl, pp.131-171, 2015. ,
DOI : 10.1111/all.12526
Staphylococcus ??-toxin induces allergic skin disease by activating mast cells, Nature, vol.76, issue.7476, pp.397-401, 2013. ,
DOI : 10.1038/nature12655
TSLP: An Epithelial Cell Cytokine that Regulates T Cell Differentiation by Conditioning Dendritic Cell Maturation, Annual Review of Immunology, vol.25, issue.1, pp.193-219, 2007. ,
DOI : 10.1146/annurev.immunol.25.022106.141718
IL-33 and Thymic Stromal Lymphopoietin in mast cell functions, European Journal of Pharmacology, vol.778, 2015. ,
DOI : 10.1016/j.ejphar.2015.04.047
An update on the role of human dendritic cells in patients with atopic dermatitis, Journal of Allergy and Clinical Immunology, vol.129, issue.4, pp.879-86 ,
DOI : 10.1016/j.jaci.2012.01.062
Does ???autoreactivity??? play a role in atopic dermatitis?, Journal of Allergy and Clinical Immunology, vol.129, issue.5, pp.1209-1224 ,
DOI : 10.1016/j.jaci.2012.02.002
Dupilumab Treatment in Adults with Moderate-to-Severe Atopic Dermatitis, New England Journal of Medicine, vol.371, issue.2, pp.130-139, 2014. ,
DOI : 10.1056/NEJMoa1314768
New pathogenic and therapeutic paradigms in atopic dermatitis, Cytokine, vol.73, issue.2, pp.311-319 ,
DOI : 10.1016/j.cyto.2014.11.023
Unravelling the complex genetic background of atopic dermatitis: from genetic association results towards novel therapeutic strategies, Archives of Dermatological Research, vol.27, issue.3 ,
DOI : 10.1007/s00403-015-1550-6
Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis, Nature Genetics, vol.48, issue.4, pp.441-447, 2006. ,
DOI : 10.1038/ng1767
Loss-of-function variations within the filaggrin gene predispose for atopic dermatitis with allergic sensitizations, Journal of Allergy and Clinical Immunology, vol.118, issue.1, pp.214-223, 2006. ,
DOI : 10.1016/j.jaci.2006.05.004
Filaggrin gene defects and risk of developing allergic sensitisation and allergic disorders: systematic review and meta-analysis, BMJ, vol.339, issue.jul08 4, p.2433, 2009. ,
DOI : 10.1136/bmj.b2433
The burden of disease associated with filaggrin mutations: A population-based, longitudinal birth cohort study, Journal of Allergy and Clinical Immunology, vol.121, issue.4, pp.872-879, 2008. ,
DOI : 10.1016/j.jaci.2008.01.026
Causes of epidermal filaggrin reduction and their role in the pathogenesis of atopic dermatitis, Journal of Allergy and Clinical Immunology, vol.134, issue.4, pp.792-801, 2014. ,
DOI : 10.1016/j.jaci.2014.06.014
Tight junction defects in patients with atopic dermatitis, Journal of Allergy and Clinical Immunology, vol.127, issue.3, pp.773-86, 2011. ,
DOI : 10.1016/j.jaci.2010.10.018
Association between polymorphisms in the SPINK5 gene and atopic dermatitis in the Japanese, Genes and Immunity, vol.4, issue.7, 2003. ,
DOI : 10.1038/sj.gene.6363889
Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis, Nature Genetics, vol.447, issue.2, pp.187-92, 2012. ,
DOI : 10.1086/519795
Variants in a Novel Epidermal Collagen Gene (COL29A1) Are Associated with Atopic Dermatitis, PLoS Biology, vol.300, issue.9, p.242, 2007. ,
DOI : 10.1371/journal.pbio.0050242.st005
Association of variation in the LAMA3 gene, encoding the alpha-chain of laminin 5, with atopic dermatitis in a German case???control cohort, BMC Dermatology, vol.8, issue.Suppl 1, p.17, 2014. ,
DOI : 10.1586/eci.11.100
New insights into the epidemiology of childhood atopic dermatitis, Allergy, vol.67, issue.2 Pt 1, pp.3-16 ,
DOI : 10.1111/all.12270
Probiotics Supplementation During Pregnancy or Infancy for the Prevention of Atopic Dermatitis, Epidemiology, vol.23, issue.3, pp.402-416, 2012. ,
DOI : 10.1097/EDE.0b013e31824d5da2
Atopic Dermatitis and the Hygiene Hypothesis Revisited, Curr Probl Dermatol, vol.41, pp.1-34, 2011. ,
DOI : 10.1159/000323290
Anthelminthic treatment during pregnancy is associated with increased risk of infantile eczema: randomisedcontrolled trial results. Pediatr Allergy Immunol Off Publ Eur Soc Pediatr Allergy Immunol, pp.305-317, 2011. ,
Effect of albendazole treatments on the prevalence of atopy in children living in communities endemic for geohelminth parasites: a cluster-randomised trial, The Lancet, vol.367, issue.9522, pp.1598-603, 2006. ,
DOI : 10.1016/S0140-6736(06)68697-2
Does early life exposure to antibiotics increase the risk of eczema? A systematic review, British Journal of Dermatology, vol.107, issue.Suppl. 1, pp.983-91, 2013. ,
DOI : 10.1111/bjd.12476
Temporal shifts in the skin microbiome associated with disease flares and treatment in children with atopic dermatitis, Genome Research, vol.22, issue.5 ,
DOI : 10.1101/gr.131029.111
Defective killing of Staphylococcus aureus in atopic dermatitis is associated with reduced mobilization of human ??-defensin-3, Journal of Allergy and Clinical Immunology, vol.122, issue.1, pp.62-70, 2008. ,
DOI : 10.1016/j.jaci.2008.04.022
Exposure to Environmental Microorganisms and Childhood Asthma, New England Journal of Medicine, vol.364, issue.8, pp.701-710, 2011. ,
DOI : 10.1056/NEJMoa1007302
Prenatal farm exposure is related to the expression of receptors of the innate immunity and to atopic sensitization in school-age children, Journal of Allergy and Clinical Immunology, vol.117, issue.4, pp.817-840, 2006. ,
DOI : 10.1016/j.jaci.2005.12.1307
Pet exposure and risk of atopic dermatitis at the pediatric age: A??meta-analysis of birth cohort studies, Journal of Allergy and Clinical Immunology, vol.132, issue.3, pp.616-638, 2013. ,
DOI : 10.1016/j.jaci.2013.04.009
Lower risk of atopic dermatitis among infants born extremely preterm compared with higher gestational age, British Journal of Dermatology, vol.87, issue.Suppl. 1, pp.1257-64, 2013. ,
DOI : 10.1111/bjd.12581
Alspac Study Team Hygiene levels in a contemporary population cohort are associated with wheezing and atopic eczema in preschool infants, Arch Dis Child, 2002. ,
A Randomised Controlled Trial of Ion-Exchange Water Softeners for the Treatment of Eczema in Children, PLoS Medicine, vol.327, issue.2, p.1000395, 2011. ,
DOI : 10.1371/journal.pmed.1000395.s002
Do fast foods cause asthma, rhinoconjunctivitis and eczema? Global findings from the International Study of Asthma and Allergies in Childhood (ISAAC) Phase Three, Thorax, vol.68, issue.4, pp.351-60 ,
DOI : 10.1136/thoraxjnl-2012-202285
Prenatal and early-life exposures alter expression of innate immunity genes: The PASTURE cohort study, Journal of Allergy and Clinical Immunology, vol.130, issue.2, pp.523-553, 2012. ,
DOI : 10.1016/j.jaci.2012.05.049
URL : https://hal.archives-ouvertes.fr/hal-00759160
Climatic Factors Are Associated with Childhood Eczema Prevalence in the United States, Journal of Investigative Dermatology, vol.133, issue.7, pp.1752-1761 ,
DOI : 10.1038/jid.2013.19
Warm, Humid, and High Sun Exposure Climates Are Associated with Poorly Controlled Eczema: PEER (Pediatric Eczema Elective Registry) Cohort, 2004???2012, Journal of Investigative Dermatology, vol.134, issue.1, pp.51-58, 2014. ,
DOI : 10.1038/jid.2013.274
Health Outcome Measures in Atopic Dermatitis: A Systematic Review of Trends in Disease Severity and Quality-of-Life Instruments 1985???2010, PLoS ONE, vol.136, issue.Suppl 48, p.17520, 2011. ,
DOI : 10.1371/journal.pone.0017520.t002
European Dermato-Epidemiology Network. What are the best outcome measurements for atopic eczema? A systematic review, J Allergy Clin Immunol, 2007. ,
The eczema area and severity index (EASI): assessment of reliability in atopic dermatitis, Experimental Dermatology, vol.44, issue.1, pp.11-19, 2001. ,
DOI : 10.1111/1523-1747.ep12297659
The Patient-Oriented Eczema Measure, Archives of Dermatology, vol.140, issue.12, pp.1513-1522, 2004. ,
DOI : 10.1001/archderm.140.12.1513
Patient-Oriented SCORAD (PO-SCORAD): a new self-assessment scale in atopic dermatitis validated in Europe, Allergy, vol.27, issue.8, pp.1114-1135, 2011. ,
DOI : 10.1111/j.1398-9995.2011.02577.x
Use of the Self-Administered Eczema Area and Severity Index by parent caregivers: results of a validation study, British Journal of Dermatology, vol.186, issue.6 ,
DOI : 10.1001/archderm.127.8.1239
Analysis of Correlations between Patient-Oriented SCORAD (PO-SCORAD) and Other Assessment Scores of Atopic Dermatitis Severity and Quality of Life, Dermatology, vol.229, issue.3, pp.248-55, 2014. ,
DOI : 10.1159/000365075
Atopic Dermatitis Burden Scale for Adults: Development and Validation of a New Assessment Tool, Acta Dermato Venereologica, vol.95, issue.6, 2014. ,
DOI : 10.2340/00015555-1945
Report from the third international consensus meeting to harmonise core outcome measures for atopic eczema/dermatitis clinical trials (HOME), British Journal of Dermatology, vol.147, issue.Suppl. 48, pp.1318-1343, 2014. ,
DOI : 10.1111/bjd.13237
Towards global consensus on outcome measures for atopic eczema research: results of the HOME II meeting, Allergy, vol.140, issue.Suppl 48, 2012. ,
DOI : 10.1111/j.1398-9995.2012.02874.x
Which HOME for atopic dermatitis?, British Journal of Dermatology, vol.66, issue.6, pp.1286-1293, 2014. ,
DOI : 10.1111/bjd.13448
Clearing up misunderstandings around core outcomes for atopic dermatitis, British Journal of Dermatology, vol.171, issue.2, 2015. ,
DOI : 10.1111/bjd.13787
Clearing up misunderstandings around core outcomes for atopic dermatitis: reply from the authors, British Journal of Dermatology, vol.230, issue.2, 2015. ,
DOI : 10.1111/bjd.13804
Using the Physician Global Assessment in a Clinical Setting to Measure and Track Patient Outcomes, JAMA Dermatology, vol.151, issue.4, 2014. ,
DOI : 10.1001/jamadermatol.2014.3513
Anti-IL-5 recombinant humanized monoclonal antibody (Mepolizumab) for the treatment of atopic dermatitis, Allergy, vol.159, issue.5, pp.693-699, 2005. ,
DOI : 10.1164/rccm.2304001
Psychological and educational interventions for atopic eczema in children, Cochrane Database Syst Rev, issue.3, p.4054, 2007. ,
Efficacy and tolerability of pale sulfonated shale oil cream 4% in the treatment of mild to moderate atopic eczema in children: a multicentre, randomized vehicle-controlled trial, Journal of the European Academy of Dermatology and Venereology, vol.156, issue.Suppl., pp.1176-82, 2010. ,
DOI : 10.1111/j.1468-3083.2010.03616.x
The Steroid-Sparing Effect of an Emollient Therapy in Infants with Atopic Dermatitis: A Randomized Controlled Study, Dermatology, vol.214, issue.1, pp.61-68, 2007. ,
DOI : 10.1159/000096915
Topical Steroids under Wet-Wrap Dressings in Atopic Dermatitis ??? A Vehicle-Controlled Trial, Dermatology, vol.204, issue.1, pp.56-65, 2002. ,
DOI : 10.1159/000051811
Systematic review of treatments for atopic eczema, Health Technol Assess Winch Engl, vol.4, issue.37, pp.1-191, 2000. ,
Established corticosteroid creams should be applied only once daily in patients with atopic eczema, BMJ, vol.334, issue.7606, p.1272, 2007. ,
DOI : 10.1136/bmj.39195.636319.80
Efficacy and tolerability of proactive treatment with topical corticosteroids and calcineurin inhibitors for atopic eczema: systematic review and meta-analysis of randomized controlled trials, British Journal of Dermatology, vol.249, issue.Suppl., pp.415-443, 2011. ,
DOI : 10.1111/j.1365-2133.2010.10030.x
Topical calcineurin inhibitors in atopic dermatitis: A systematic review and meta-analysis, Journal of Dermatological Science, vol.54, issue.2, pp.76-87, 2009. ,
DOI : 10.1016/j.jdermsci.2009.02.002
Tacrolimus ointment is more effective than pimecrolimus cream with a similar safety profile in the treatment of atopic dermatitis: Results from 3 randomized, comparative studies, Journal of the American Academy of Dermatology, vol.52, issue.5, 2005. ,
DOI : 10.1016/j.jaad.2004.12.038
A body-weight-independent dosing regimen of cyclosporine microemulsion is effective in severe atopic dermatitis and improves the quality of life, Journal of the American Academy of Dermatology, vol.42, issue.4, pp.653-662, 2000. ,
DOI : 10.1016/S0190-9622(00)90180-4
Double-blind, controlled, crossover study of cyclosporin in adults with severe refractory atopic dermatitis, The Lancet, vol.338, issue.8760, pp.137-177, 1991. ,
DOI : 10.1016/0140-6736(91)90134-B
Cyclosporin in atopic dermatitis: a multicentre placebo-controlled study, British Journal of Dermatology, vol.129, issue.5, pp.634-674, 1994. ,
DOI : 10.1016/S0140-6736(89)92941-3
Maintenance treatment with cyclosporin in atopic eczema, British Journal of Dermatology, vol.122, issue.3, pp.376-80, 1994. ,
DOI : 10.1016/0140-6736(91)90134-B
Cyclosporin in the treatment of patients with atopic eczema ? a systematic review and meta-analysis, Journal of the European Academy of Dermatology and Venereology, vol.26, issue.0, pp.606-625, 2007. ,
DOI : 10.1067/mjd.2001.117010
The Efficacy and Safety of Long-term Oral Cyclosporine Treatment for Patients with Atopic Dermatitis, Annals of Dermatology, vol.22, issue.1, pp.9-15, 2010. ,
DOI : 10.5021/ad.2010.22.1.9
Cyclosporin for severe childhood atopic dermatitis: short course versus continuous therapy, British Journal of Dermatology, vol.338, issue.Suppl. 48, 2000. ,
DOI : 10.1046/j.1365-2133.2000.03241.x
Cyclosporin in atopic dermatitis: time to relapse and effect of intermittent therapy, British Journal of Dermatology, vol.324, issue.1, pp.106-118, 1995. ,
DOI : 10.1001/archderm.129.10.1273
The efficacy, tolerability and safety of a new oral formulation of Sandimmun-Sandimmun Neoral in severe refractory atopic dermatitis, J Eur Acad Dermatol Venereol JEADV, vol.11, issue.3, pp.240-246, 1998. ,
Retrospective Review of Relapse after Systemic Cyclosporine in Children with Atopic Dermatitis, Pediatric Dermatology, vol.135, issue.Suppl 48, pp.36-40 ,
DOI : 10.1111/pde.12367
The use of cyclosporine in dermatology: Part II, Journal of the American Academy of Dermatology, vol.63, issue.6, pp.949-72, 2010. ,
DOI : 10.1016/j.jaad.2010.02.062
Review of cyclosporine immunosuppressive safety data in dermatology patients after two decades of use, J Drugs Dermatol JDD, vol.4, issue.2, pp.189-94, 2005. ,
Risk of Malignancies in Psoriasis Patients Treated with Cyclosporine: a 5 y Cohort Study, Journal of Investigative Dermatology, vol.120, issue.2, pp.211-217, 2003. ,
DOI : 10.1046/j.1523-1747.2003.12040.x
Squamous-cell cancer of the skin in patients given PUVA and ciclosporin: nested cohort crossover study, The Lancet, vol.358, issue.9287, pp.1042-1047, 2001. ,
DOI : 10.1016/S0140-6736(01)06179-7
Drug survival for cyclosporin A in a long-term daily practice cohort of adult patients with atopic dermatitis, Br J Dermatol Feb, vol.13, 2015. ,
Efficacy and safety of long-term treatment with cyclosporin A for atopic dermatitis, Journal of the European Academy of Dermatology and Venereology, vol.112, issue.1, pp.85-94, 2007. ,
DOI : 10.1111/j.1365-2133.1995.tb08633.x
Experience with low-dose methotrexate for the treatment of eczema in the elderly, Journal of the American Academy of Dermatology, vol.48, issue.3, pp.417-426, 2003. ,
DOI : 10.1067/mjd.2003.137
Successful treatment of severe atopic dermatitis with methotrexate, Clinical and Experimental Dermatology, vol.370, issue.4, pp.436-443, 2005. ,
DOI : 10.1097/00002281-199905000-00012
Methotrexate for the treatment of adult atopic dermatitis, Eur J Dermatol EJD, vol.16, issue.2, pp.155-163, 2006. ,
An open-label, dose-ranging study of methotrexate for moderate-to-severe adult atopic eczema, British Journal of Dermatology, vol.16, issue.2, pp.346-51, 2007. ,
DOI : 10.1111/j.1365-2133.2005.06592.x
Low-dose methotrexate treatment for moderate-to-severe atopic dermatitis in adults, Journal of the European Academy of Dermatology and Venereology, vol.120, issue.6, pp.43-52, 2010. ,
DOI : 10.1111/j.1468-3083.2009.03351.x
Methotrexate versus cyclosporine in the treatment of severe atopic dermatitis in children: a multicenter experience from Egypt, European Journal of Pediatrics, vol.135, issue.3, pp.351-357, 2013. ,
DOI : 10.1007/s00431-012-1893-3
Efficacit?? du m??thotrexate (MTX) versus ciclosporine (Cy) dans la dermatite atopique (DA) mod??r??e ?? s??v??re de l???adulte, Annales de Dermatologie et de V??n??r??ologie, vol.141, issue.12, p.302, 2014. ,
DOI : 10.1016/j.annder.2014.09.168
The carcinogenic risk of treatments for severe psoriasis Photochemotherapy Follow-up Study. Cancer, pp.2759-64, 1994. ,
Lymphoma Risk in Psoriasis, Archives of Dermatology, vol.142, issue.9, pp.1132-1137, 2006. ,
DOI : 10.1001/archderm.142.9.1132
Long-term safety of methotrexate monotherapy in patients with rheumatoid arthritis: a systematic literature research, Annals of the Rheumatic Diseases, vol.68, issue.7, pp.1100-1104, 2009. ,
DOI : 10.1136/ard.2008.093690
Azathioprine for atopic dermatitis, Clinical and Experimental Dermatology, vol.33, issue.5, pp.369-75, 2001. ,
DOI : 10.1046/j.1365-2133.1996.d01-1061.x
Azathioprine in severe adult atopic dermatitis: a double-blind, placebo-controlled, crossover trial, British Journal of Dermatology, vol.88, issue.2, 2002. ,
DOI : 10.1001/archderm.131.2.193
Azathioprine dosed by thiopurine methyltransferase activity for moderate-to-severe atopic eczema: a double-blind, randomised controlled trial, The Lancet, vol.367, issue.9513, pp.839-885, 2006. ,
DOI : 10.1016/S0140-6736(06)68340-2
A retrospective evaluation of azathioprine in severe childhood atopic eczema, using thiopurine methyltransferase levels to exclude patients at high risk of myelosuppression, British Journal of Dermatology, vol.46, issue.2, pp.308-323, 2002. ,
DOI : 10.1016/S0140-6736(94)92150-4
The adverse effect profile of oral azathioprine in pediatric atopic dermatitis, and recommendations for monitoring, Journal of the American Academy of Dermatology, vol.72, issue.1, pp.108-122 ,
DOI : 10.1016/j.jaad.2014.08.048
Oral azathioprine for recalcitrant pediatric atopic dermatitis: Clinical response and thiopurine monitoring, Journal of the American Academy of Dermatology, vol.68, issue.1, pp.29-35, 2013. ,
DOI : 10.1016/j.jaad.2012.07.001
A randomized trial of methotrexate versus azathioprine for severe atopic eczema, Journal of Allergy and Clinical Immunology, vol.128, issue.2, 2011. ,
DOI : 10.1016/j.jaci.2011.03.024
Risk of developing certain malignancies is related to duration of immunosuppressive drug exposure in patients with rheumatic diseases, J Rheumatol, 1999. ,
Risk of cancer from azathioprine therapy in multiple sclerosis: A case-control study, Neurology, vol.46, issue.6, pp.1607-1619, 1996. ,
DOI : 10.1212/WNL.46.6.1607
Azathioprine treatment photosensitizes human skin to ultraviolet A radiation, British Journal of Dermatology, vol.378, issue.1, 2008. ,
DOI : 10.1016/j.dnarep.2006.11.003
Mycophenolate mofetil therapy for moderate to severe atopic dermatitis, Clinical and Experimental Dermatology, vol.92, issue.0, pp.23-30, 2007. ,
DOI : 10.1046/j.1365-2133.2000.03623.x
Severe adult atopic dermatitis: treatment with mycophenolate mofetil in 8 patients]. Actas Dermo-Sifiliográficas, pp.883-890, 2009. ,
Enteric-coated mycophenolate sodium versus cyclosporin A??as long-term treatment in adult patients with severe atopic dermatitis: A??randomized controlled trial, Journal of the American Academy of Dermatology, vol.64, issue.6, pp.1074-84, 2011. ,
DOI : 10.1016/j.jaad.2010.04.027
Clinical improvement and immunohistochemical findings in severe atopic dermatitis treated with interferon gamma, Journal of the American Academy of Dermatology, vol.42, issue.6, pp.1033-1073, 2000. ,
DOI : 10.1067/mjd.2000.104793
Recombinant interferon gamma therapy for atopic dermatitis, Journal of the American Academy of Dermatology, vol.28, issue.2, pp.189-97, 1993. ,
DOI : 10.1016/0190-9622(93)70026-P
Open-label, pilot study examining sequential therapy with oral tacrolimus and topical tacrolimus for severe atopic dermatitis, Journal of the American Academy of Dermatology, vol.67, issue.4, pp.636-677, 2012. ,
DOI : 10.1016/j.jaad.2011.10.033
Poor efficacy of oral tacrolimus in the treatment of severe generalized atopic eczema in adults: A small retrospective case series, Australasian Journal of Dermatology, vol.25, issue.1, pp.295-302, 2012. ,
DOI : 10.1111/j.1440-0960.2011.00789.x
Prednisolone vs. ciclosporin for severe adult eczema. An investigator-initiated double-blind placebo-controlled multicentre trial, British Journal of Dermatology, vol.143, issue.Suppl. 62, pp.661-669, 2010. ,
DOI : 10.1111/j.1365-2133.2009.09561.x
Ten years experience with oral immunosuppressive treatment in adult patients with atopic dermatitis in two academic centres, Journal of the European Academy of Dermatology and Venereology, vol.169, issue.10, 2009. ,
DOI : 10.1111/jdv.13064
Drug combinations with methotrexate to treat rheumatoid arthritis, Clin Exp Rheumatol, vol.28, issue.5, pp.52-59, 2010. ,
Biologics in atopic dermatitis, JDDG: Journal der Deutschen Dermatologischen Gesellschaft, vol.64, issue.7, pp.174-182, 2012. ,
DOI : 10.1111/j.1610-0387.2011.07760.x
Low-dose anti-IgE therapy in patients with atopic eczema with high serum IgE levels, Journal of Allergy and Clinical Immunology, vol.120, issue.5, pp.1223-1228, 2007. ,
DOI : 10.1016/j.jaci.2007.08.060
Omalizumab for the treatment of atopic dermatitis. Actas Dermo- Sifiliográficas, pp.624-632, 2012. ,
Omalizumab therapy in atopic dermatitis: depletion of IgE does not improve the clinical course - a randomized, placebo-controlled and double blind pilot study, JDDG: Journal der Deutschen Dermatologischen Gesellschaft, vol.131, issue.12, pp.990-998, 2010. ,
DOI : 10.1111/j.1610-0387.2010.07497.x
Failure of omalizumab for treatment of severe adult atopic dermatitis, Journal of the American Academy of Dermatology, vol.53, issue.2, pp.338-378, 2005. ,
DOI : 10.1016/j.jaad.2005.02.014
Alefacept (lymphocyte function-associated molecule 3/IgG fusion protein) treatment for atopic eczema, Journal of Allergy and Clinical Immunology, vol.122, issue.2, pp.423-427, 2008. ,
DOI : 10.1016/j.jaci.2008.06.010
Alefacept for moderate to severe atopic dermatitis: A pilot study in adults, Journal of the American Academy of Dermatology, vol.58, issue.6, pp.984-993, 2008. ,
DOI : 10.1016/j.jaad.2008.02.007
Infliximab in the treatment of moderate to severe atopic dermatitis, Journal of the American Academy of Dermatology, vol.52, issue.3, pp.522-528, 2005. ,
DOI : 10.1016/j.jaad.2004.11.022
Anti-CD20 (rituximab) treatment improves atopic eczema, Journal of Allergy and Clinical Immunology, vol.121, issue.1, pp.122-130, 2008. ,
DOI : 10.1016/j.jaci.2007.11.016
Possible new therapeutic strategy to regulate atopic dermatitis through upregulating filaggrin expression, Journal of Allergy and Clinical Immunology, vol.133, issue.1, pp.139-185, 2014. ,
DOI : 10.1016/j.jaci.2013.07.027
Recombinant Filaggrin Is Internalized and Processed to Correct Filaggrin Deficiency, Journal of Investigative Dermatology, vol.134, issue.2, 2014. ,
DOI : 10.1038/jid.2013.284