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Master Thesis

Représentation des diagnostics de tumeurs utilisés par les registres des cancers par l’intermédiaire du NCI thesaurus : évaluation de cette terminologie comme outil pour l’utilisation conjointe de données en cancérologie

Abstract : Background: Several terminologies are routinely used to encode cancer diagnosis. To conjoint use information coming from several sources, it is necessary to be able to map similar diagnoses, encoded with those different terminologies, ie to attach under one concept different codes, without change or loss of information. The NCI thesaurus (NCIt) seemed to be a good foundation to develop a pivot terminology, to consensually represent in a centralized way the concepts from different diagnostic terminologies in oncology. The ICDO was chosen to begin the mapping work towards this target terminology. Objective: The objective was to evaluate the possibility of representing the diagnostic data from a general cancers register of adult through the NCIt concepts, using a validated mapping previously established between ICDO and NCIt and relationships between NCIt concepts. Method: The first phase involved developing a mapping from ICDO to NCIt. The second phase focused on evaluating the possibility of representing the actual diagnoses of General Cancer Registry of the Gironde (RGCG), coded ICDO, with the nCit precoordinated concepts. For each phase, a manual validation by a team of physicians was performed. Results: On January 31, 2015, the validation by the team of doctors had yielded 605 valid mappings of an ICDO code to a NCIt code (40,3% of the 1500 ICDO codes). There were 21 694 tumors (52,20% of the 41,553 tumors registrated by the RGCG during the inclusion period) with a complete mapping of their diagnosis. A total of 7822 tumors (18.8% of the 41,553 tumors registrated by the RGCG) had a diagnosis that pointed to a valid NCIt pre-coordinated diagnosis.
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Master Thesis
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https://dumas.ccsd.cnrs.fr/dumas-01206467
Contributor : Bu Carreire Université de Bordeaux <>
Submitted on : Tuesday, September 29, 2015 - 10:26:15 AM
Last modification on : Wednesday, August 23, 2017 - 4:29:28 PM
Long-term archiving on: : Wednesday, December 30, 2015 - 10:24:33 AM

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Bérénice Bréchat-Huet. Représentation des diagnostics de tumeurs utilisés par les registres des cancers par l’intermédiaire du NCI thesaurus : évaluation de cette terminologie comme outil pour l’utilisation conjointe de données en cancérologie. Médecine humaine et pathologie. 2015. ⟨dumas-01206467⟩

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