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Master Thesis

Évaluation de l’équilibre des AVK post-hospitalisation, chez des sujets âgés, traités pour une Fibrillation Atriale : FAREMBOL-AMBU : étude prospective sur un territoire géographique déterminé de la région Aquitaine

Abstract : Introduction: Global time in therapeutic range (TTR), for patients over 75 years old in a specific geographic area of Aquitaine was 58%. The purpose of the prospective real life FAREMBOL AMBU trial, was to assess the impact of several actions on the TTR improving. Methods: Throughout one year, several interventions were launched including oral anticoagulation computer-aided management, communication between health professionals and patient’s information. TTR was computed according to Rosendaal's method. Results: The overall follow-up duration was of 74 patient-years including 210 patients. The time spent between therapeutic range 2 to 3 was 64%. During follow-up 47 adverse events occurred. 5 were bleeding complications (TTR = 34%), 9 were ischemic strokes (TTR = 48%) and 33 were fatal (TTR 57%). The longer the time in therapeutic range, the better the survival (r=0.8593). Conclusion: The study proved that the actions taken have improved oral anticoagulation management. These good management practices should be applied in every hospital and by ambulatory physicians.
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https://dumas.ccsd.cnrs.fr/dumas-01212706
Contributor : Bu Carreire Université de Bordeaux <>
Submitted on : Wednesday, October 7, 2015 - 9:55:09 AM
Last modification on : Sunday, October 25, 2020 - 7:04:54 AM
Long-term archiving on: : Friday, January 8, 2016 - 10:18:20 AM

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  • HAL Id : dumas-01212706, version 1

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Dorothée Bureau. Évaluation de l’équilibre des AVK post-hospitalisation, chez des sujets âgés, traités pour une Fibrillation Atriale : FAREMBOL-AMBU : étude prospective sur un territoire géographique déterminé de la région Aquitaine . Médecine humaine et pathologie. 2015. ⟨dumas-01212706⟩

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