:. Apport-dans-l-'évaluation-pronostique, I. Cirrhose, and M. Irm, 38 A. Bases de l'acquisition d'une image en IRM

:. Le-phénomène-de-résonance-magnétique-nucléaire, 39 a) Notion de moment magnétique et fréquence de Larmor : 39 b) Notion d'aimantation macroscopique, p.41

I. Acquisition-et-formation-d-'une-image, 44 a) Notion de gradients et transformée de, p.44

:. Artefacts-cinétiques, 53 c) Artefacts liés à la séquence EPI, p.55

R. La-mesure-de-la-relaxation and R. , 60 2. La quantification de la graisse intra-hépatique, p.62

:. La-spectroscopie, 68 d) La technique d'excitation sélective spectrale et spatiale

:. Elastographie-par-résonance-magnétique, 72 a) Généralités, 72 b) Apport dans la quantification de la fibrose hépatique, p.73

D. Schuppan and N. Afdhal, Liver cirrhosis. The Lancet. 14 mars, pp.838-51, 2008.

A. Sanyal, J. Bosch, A. Blei, and V. Arroyo, Portal Hypertension and Its Complications, Gastroenterology, vol.134, issue.6, pp.1715-1743, 2008.
DOI : 10.1053/j.gastro.2008.03.007

G. Garcia-tsao, S. Friedman, J. Iredale, and M. Pinzani, Now there are many (stages) where before there was one: In search of a pathophysiological classification of cirrhosis, Hepatology, vol.58, issue.2 Suppl 1, pp.1445-1454, 2010.
DOI : 10.1002/hep.23478

Y. Gandon, D. Olivié, D. Guyader, C. Aubé, F. Oberti et al., Non-invasive assessment of hepatic iron stores by MRI. The Lancet, 31 janv, vol.363, issue.9406, pp.357-62, 2004.

M. Noureddin, J. Lam, M. Peterson, M. Middleton, G. Hamilton et al., Utility of magnetic resonance imaging versus histology for quantifying changes in liver fat in nonalcoholic fatty liver disease trials, Hepatology, vol.375, issue.6, 2013.
DOI : 10.1002/hep.26455

M. Kanematsu, S. Goshima, H. Watanabe, H. Kondo, H. Kawada et al., Diffusion/Perfusion MR Imaging of the Liver: Practice, Challenges, and Future, Magnetic Resonance in Medical Sciences, vol.11, issue.3
DOI : 10.2463/mrms.11.151

J. Klasen, R. Lanzman, H. Wittsack, G. Kircheis, J. Schek et al., Diffusion-weighted imaging (DWI) of the spleen in patients with liver cirrhosis and portal hypertension, Magnetic Resonance Imaging, vol.31, issue.7, pp.1092-1098, 2013.
DOI : 10.1016/j.mri.2013.01.003

J. Schulz-menger and M. Friedrich, Magnetic Resonance Imaging in Patients with Cardiomyopathies: When and Why, Herz, vol.25, issue.4, pp.384-91, 2000.
DOI : 10.1007/s000590050030

R. Banerjee, M. Pavlides, E. Tunnicliffe, S. Piechnik, N. Sarania et al., Multiparametric magnetic resonance for the non-invasive diagnosis of liver disease, Journal of Hepatology, vol.60, issue.1, pp.69-77, 2014.
DOI : 10.1016/j.jhep.2013.09.002

S. Giri, Y. Chung, A. Merchant, G. Mihai, S. Rajagopalan et al., T2 quantification for improved detection of myocardial edema, Journal of Cardiovascular Magnetic Resonance, vol.11, issue.1, p.56, 2009.
DOI : 10.1186/1532-429X-11-56

E. Tsochatzis, J. Bosch, and A. Burroughs, Liver cirrhosis. The Lancet. 23 mai 2014, pp.1749-61

M. Blachier, H. Leleu, M. Peck-radosavljevic, D. Valla, and F. Roudot-thoraval, The burden of liver disease in Europe: A review of available epidemiological data, Journal of Hepatology, vol.58, issue.3, pp.593-608, 2013.
DOI : 10.1016/j.jhep.2012.12.005

J. García-pagán, J. Gracia-sancho, and J. Bosch, Functional aspects on the pathophysiology of portal hypertension in cirrhosis, Journal of Hepatology, vol.57, issue.2, pp.458-61, 2012.
DOI : 10.1016/j.jhep.2012.03.007

R. Franchis and . De, Updating Consensus in Portal Hypertension: Report of the Baveno III Consensus Workshop on definitions, methodology and therapeutic strategies in portal hypertension, Journal of Hepatology, vol.33, issue.5, pp.846-52, 2000.
DOI : 10.1016/S0168-8278(00)80320-7

R. Groszmann and J. Abraldes, Portal Hypertension, Journal of Clinical Gastroenterology, vol.39, issue.Supplement 2, pp.125-155, 2005.
DOI : 10.1097/01.mcg.0000155552.14396.3d

H. Awaya, D. Mitchell, T. Kamishima, G. Holland, K. Ito et al., Cirrhosis: Modified Caudate???Right Lobe Ratio, Radiology, vol.224, issue.3, pp.769-74, 2002.
DOI : 10.1148/radiol.2243011495

A. Martínez-noguera, E. Montserrat, S. Torrubia, and J. Villalba, Doppler in hepatic cirrhosis and chronic hepatitis, Seminars in Ultrasound, CT and MRI, vol.23, issue.1, pp.19-36, 2002.
DOI : 10.1016/S0887-2171(02)90027-2

W. Rector, J. Campra, P. Ralls, and M. Charms, Utility and limitations of splanchnic venous ultrasonography in diagnosis of portal hypertension, Journal of Clinical Ultrasound, vol.154, issue.9, pp.689-96, 1986.
DOI : 10.1002/jcu.1870140905

E. Giannini, A. Zaman, A. Kreil, A. Floreani, P. Dulbecco et al., Platelet Count/Spleen Diameter Ratio for the Noninvasive Diagnosis of Esophageal Varices: Results of a Multicenter, Prospective, Validation Study, The American Journal of Gastroenterology, vol.101, issue.11, pp.2511-2520, 2006.
DOI : 10.1111/j.1572-0241.2006.00874.x

F. Barrera, A. Riquelme, A. Soza, A. Contreras, G. Barrios et al., Platelet count/spleen diameter ratio for non-invasive prediction of high risk esophageal varices in cirrhotic patients, Ann Hepatol. déc, vol.8, issue.4, pp.325-355, 2009.

M. Burrel, J. Llovet, C. Ayuso, C. Iglesias, M. Sala et al., MRI angiography is superior to helical CT for detection of HCC prior to liver transplantation: An explant correlation, Hepatology, vol.217, issue.4, pp.1034-1076, 2003.
DOI : 10.1002/hep.1840380430

G. Garcia-tsao and J. Bosch, Management of Varices and Variceal Hemorrhage in Cirrhosis, New England Journal of Medicine, vol.362, issue.9, pp.823-855, 2010.
DOI : 10.1056/NEJMra0901512

D. Amico, G. Pagliaro, L. Bosch, and J. , The treatment of portal hypertension: A meta-analytic review, Hepatology, vol.6, issue.1, pp.332-54, 1995.
DOI : 10.1002/hep.1840220145

D. Jensen, Endoscopic screening for varices in cirrhosis: Findings, implications, and outcomes, Gastroenterology, vol.122, issue.6, pp.1620-1650, 2002.
DOI : 10.1053/gast.2002.33419

L. Gluud, S. Klingenberg, D. Nikolova, and C. Gluud, Banding Ligation Versus Beta-Blockers as Primary Prophylaxis in Esophageal Varices: Systematic Review of Randomized Trials, The American Journal of Gastroenterology, vol.21, issue.12, pp.2842-2850, 2007.
DOI : 10.1001/jama.295.10.1147

R. Gonzalez, J. Zamora, J. Gomez-camarero, L. Molinero, R. Bañares et al., Meta-analysis: Combination Endoscopic and Drug Therapy to Prevent Variceal Rebleeding in Cirrhosis, Annals of Internal Medicine, vol.149, issue.2, pp.109-131, 2008.
DOI : 10.7326/0003-4819-149-2-200807150-00007

D. Amico, G. Garcia-tsao, G. Pagliaro, and L. , Natural history and prognostic indicators of survival in cirrhosis: A systematic review of 118 studies, Journal of Hepatology, vol.44, issue.1, pp.217-248, 2006.
DOI : 10.1016/j.jhep.2005.10.013

G. Fede, D. Amico, G. Arvaniti, V. Tsochatzis, E. Germani et al., Renal failure and cirrhosis: A systematic review of mortality and prognosis, Journal of Hepatology, vol.56, issue.4, pp.810-818, 2012.
DOI : 10.1016/j.jhep.2011.10.016

B. Runyon, Management of adult patients with ascites due to cirrhosis: An update, Hepatology, vol.101, issue.6, pp.2087-107, 2009.
DOI : 10.1002/hep.22853

V. Arvaniti, D. Amico, G. Fede, G. Manousou, P. Tsochatzis et al., Infections in Patients With Cirrhosis Increase Mortality Four-Fold and Should Be Used in Determining Prognosis, Gastroenterology, vol.139, issue.4, pp.1246-56, 2010.
DOI : 10.1053/j.gastro.2010.06.019

J. Fernández, M. Navasa, R. Planas, S. Montoliu, D. Monfort et al., Primary Prophylaxis of Spontaneous Bacterial Peritonitis Delays Hepatorenal Syndrome and Improves Survival in Cirrhosis, Gastroenterology, vol.133, issue.3, pp.818-842, 2007.
DOI : 10.1053/j.gastro.2007.06.065

P. Jepsen, P. Ott, P. Andersen, H. Sørensen, and H. Vilstrup, Clinical course of alcoholic liver cirrhosis: A Danish population-based cohort study, Hepatology, vol.244, issue.5, pp.1675-82, 2010.
DOI : 10.1002/hep.23500

B. Sharma, P. Sharma, A. Agrawal, and S. Sarin, Secondary Prophylaxis of Hepatic Encephalopathy: An Open-Label Randomized Controlled Trial of Lactulose Versus Placebo, Gastroenterology, vol.137, issue.3, pp.885-91, 2009.
DOI : 10.1053/j.gastro.2009.05.056

C. Child and J. Turcotte, Surgery and portal hypertension, Major Probl Clin Surg, vol.1, pp.1-85, 1964.

R. Pugh, I. Murray-lyon, J. Dawson, M. Pietroni, and R. Williams, Transection of the oesophagus for bleeding oesophageal varices, British Journal of Surgery, vol.1, issue.8, pp.646-655, 1973.
DOI : 10.1002/bjs.1800600817

C. Infante-rivard, S. Esnaola, and J. Villeneuve, Clinical and statistical validity of conventional prognostic factors in predicting short-term survival among cirrhotics, Hepatology, vol.5, issue.4, pp.660-664, 1987.
DOI : 10.1002/hep.1840070408

P. Kamath, R. Wiesner, M. Malinchoc, W. Kremers, T. Therneau et al., A model to predict survival in patients with end-stage liver disease, Hepatology, vol.33, issue.2, pp.464-70, 2001.
DOI : 10.1053/jhep.2001.22172

R. Wiesner, E. Edwards, R. Freeman, A. Harper, R. Kim et al., Model for end-stage liver disease (MELD) and allocation of donor livers, Gastroenterology, vol.124, issue.1, pp.91-97, 2003.
DOI : 10.1053/gast.2003.50016

A. Bravo, S. Sheth, and S. Chopra, Liver Biopsy, New England Journal of Medicine, vol.344, issue.7, pp.495-500, 2001.
DOI : 10.1056/NEJM200102153440706

G. Vanbiervliet, G. Pomier-layrargues, and P. Huet, Diagnostic invasif de l???hypertention portale au cours des h??patopathies chroniques, Gastroent??rologie Clinique et Biologique, vol.29, issue.10, pp.988-96, 2005.
DOI : 10.1016/S0399-8320(05)88171-0

D. Amico, G. Garcia-pagan, J. Luca, A. Bosch, and J. , Hepatic vein pressure gradient reduction and prevention of variceal bleeding in cirrhosis: a systematic review, Gastroenterology. nov, vol.131, issue.5, pp.1611-1635, 2006.

F. Imbert-bismut, V. Ratziu, L. Pieroni, C. F. Benhamou, Y. Poynard et al., Biochemical markers of liver fibrosis in patients with hepatitis C virus infection: a prospective study, The Lancet, vol.357, issue.9262, pp.1069-75, 2001.
DOI : 10.1016/S0140-6736(00)04258-6

L. Adams, M. Bulsara, E. Rossi, B. Deboer, D. Speers et al., Hepascore: An Accurate Validated Predictor of Liver Fibrosis in Chronic Hepatitis C Infection, Clinical Chemistry, vol.51, issue.10, pp.1867-73, 2005.
DOI : 10.1373/clinchem.2005.048389

P. Calès, F. Oberti, S. Michalak, I. Hubert-fouchard, M. Rousselet et al., A novel panel of blood markers to assess the degree of liver fibrosis, Hepatology, vol.39, issue.6, pp.1373-81, 2005.
DOI : 10.1002/hep.20935

N. Frulio and H. Trillaud, Ultrasound elastography in liver, Diagnostic and Interventional Imaging, vol.94, issue.5, pp.515-549, 2013.
DOI : 10.1016/j.diii.2013.02.005

J. Boursier, J. Zarski, V. De-ledinghen, M. Rousselet, N. Sturm et al., Determination of reliability criteria for liver stiffness evaluation by transient elastography, Hepatology, vol.21, issue.3, pp.1182-91, 2013.
DOI : 10.1002/hep.25993

D. Roulot, S. Czernichow, L. Clésiau, H. Costes, J. Vergnaud et al., Liver stiffness values in apparently healthy subjects: Influence of gender and metabolic syndrome, Journal of Hepatology, vol.48, issue.4, pp.606-619, 2008.
DOI : 10.1016/j.jhep.2007.11.020

M. Fraquelli, C. Rigamonti, G. Casazza, D. Conte, M. Donato et al., Reproducibility of transient elastography in the evaluation of liver fibrosis in patients with chronic liver disease, Gut, vol.56, issue.7, pp.968-73, 2007.
DOI : 10.1136/gut.2006.111302

V. De-lédinghen, V. Wong, J. Vergniol, G. Wong, J. Foucher et al., Diagnosis of liver fibrosis and cirrhosis using liver stiffness measurement: Comparison between M and XL probe of FibroScan??, Journal of Hepatology, vol.56, issue.4, pp.833-842, 2012.
DOI : 10.1016/j.jhep.2011.10.017

M. Ziol, A. Handra-luca, A. Kettaneh, C. Christidis, F. Mal et al., Noninvasive assessment of liver fibrosis by measurement of stiffness in patients with chronic hepatitis C, Hepatology, vol.38, issue.1, pp.48-54, 2005.
DOI : 10.1002/hep.20506

P. Marcellin, M. Ziol, P. Bedossa, C. Douvin, R. Poupon et al., Non-invasive assessment of liver fibrosis by stiffness measurement in patients with chronic hepatitis B, Liver International, vol.29, issue.2, pp.242-249, 2009.
DOI : 10.1111/j.1478-3231.2008.01802.x

L. De, V. Douvin, C. Kettaneh, A. Ziol, M. Roulot et al., Diagnosis of Hepatic Fibrosis and Cirrhosis by Transient Elastography in HIV/Hepatitis C Virus-Coinfected Patients, JAIDS J Acquir Immune Defic Syndr. févr, vol.41, issue.2, pp.175-184, 2006.

V. Wong, J. Vergniol, G. Wong, J. Foucher, H. Chan et al., Diagnosis of fibrosis and cirrhosis using liver stiffness measurement in nonalcoholic fatty liver disease, Hepatology, vol.50, issue.Suppl 1, pp.454-62, 2010.
DOI : 10.1002/hep.23312

P. Nahon, A. Kettaneh, I. Tengher-barna, M. Ziol, V. De-lédinghen et al., Assessment of liver fibrosis using transient elastography in patients with alcoholic liver disease, Journal of Hepatology, vol.49, issue.6, pp.1062-1070, 2008.
DOI : 10.1016/j.jhep.2008.08.011

?. Friedrich, M. Rust, M. Ong, S. Martens, C. Sarrazin et al., Performance of Transient Elastography for the Staging of Liver Fibrosis: A Meta-Analysis, Gastroenterology, vol.134, issue.4, pp.960-74, 2008.
DOI : 10.1053/j.gastro.2008.01.034

M. Sánchez-conde, M. Montes-ramírez, P. Miralles, C. Alvarez, J. Bellón et al., Comparison of transient elastography and liver biopsy for the assessment of liver fibrosis in HIV/hepatitis C virus-coinfected patients and correlation with noninvasive serum markers, Journal of Viral Hepatitis, vol.57, issue.9, pp.280-286, 2010.
DOI : 10.1111/j.1365-2893.2009.01180.x

S. Augustin, L. Millán, A. González, M. Martell, A. Gelabert et al., Detection of early portal hypertension with routine data and liver stiffness in patients with asymptomatic liver disease: A prospective study, Journal of Hepatology, vol.60, issue.3, pp.561-570, 2014.
DOI : 10.1016/j.jhep.2013.10.027

F. Vizzutti, U. Arena, R. Romanelli, L. Rega, M. Foschi et al., Liver stiffness measurement predicts severe portal hypertension in patients with HCV-related cirrhosis, Hepatology, vol.43, issue.5, pp.1290-1297, 2007.
DOI : 10.1002/hep.21665

L. Castera, M. Pinzani, and J. Bosch, Non invasive evaluation of portal hypertension using transient elastography, Journal of Hepatology, vol.56, issue.3, pp.696-703, 2012.
DOI : 10.1016/j.jhep.2011.07.005

J. Vergniol, J. Foucher, E. Terrebonne, P. Bernard, B. Le-bail et al., Noninvasive Tests for Fibrosis and Liver Stiffness Predict 5-Year Outcomes of Patients With Chronic Hepatitis C, Gastroenterology, vol.140, issue.7, pp.1970-1979, 2011.
DOI : 10.1053/j.gastro.2011.02.058

V. De-lédinghen, J. Vergniol, C. Barthe, J. Foucher, F. Chermak et al., Non-invasive tests for fibrosis and liver stiffness predict 5-year survival of patients chronically infected with hepatitis B virus, Alimentary Pharmacology & Therapeutics, vol.16, issue.10, pp.979-88, 2013.
DOI : 10.1111/apt.12307

S. Bota, I. Sporea, R. Sirli, A. Popescu, M. D?nil? et al., Factors that influence the correlation of acoustic radiation force impulse (ARFI), elastography with liver fibrosis, Med Ultrason. juin, vol.13, issue.2, pp.135-175, 2011.

S. Bota, I. Sporea, R. Sirli, A. Popescu, M. Danila et al., Intra- and Interoperator Reproducibility of Acoustic Radiation Force Impulse (ARFI) Elastography???Preliminary Results, Ultrasound in Medicine & Biology, vol.38, issue.7, pp.1103-1111, 2012.
DOI : 10.1016/j.ultrasmedbio.2012.02.032

Y. Takuma, K. Nouso, Y. Morimoto, J. Tomokuni, A. Sahara et al., Measurement of Spleen Stiffness by Acoustic Radiation Force Impulse Imaging Identifies Cirrhotic Patients With Esophageal Varices, Gastroenterology, vol.144, issue.1, pp.92-101, 2013.
DOI : 10.1053/j.gastro.2012.09.049

C. Cassinotto, B. Lapuyade, A. Aït-ali, J. Vergniol, D. Gaye et al., Liver Fibrosis: Noninvasive Assessment with Acoustic Radiation Force Impulse Elastography???Comparison with FibroScan M and XL Probes and FibroTest in Patients with Chronic Liver Disease, Radiology, vol.269, issue.1, pp.283-92, 2013.
DOI : 10.1148/radiol.13122208

I. Sporea, Is ARFI elastography reliable for predicting fibrosis severity in chronic HCV hepatitis?, World Journal of Radiology, vol.3, issue.7, p.188, 2011.
DOI : 10.4329/wjr.v3.i7.188

M. Friedrich-rust, J. Nierhoff, M. Lupsor, I. Sporea, C. Fierbinteanu-braticevici et al., Performance of Acoustic Radiation Force Impulse imaging for the staging of liver fibrosis: a pooled meta-analysis, Journal of Viral Hepatitis, vol.59, issue.Suppl. 1, pp.212-221, 2012.
DOI : 10.1111/j.1365-2893.2011.01537.x

I. Sporea, S. Bota, M. Peck-radosavljevic, R. Sirli, H. Tanaka et al., Acoustic Radiation Force Impulse Elastography for fibrosis evaluation in patients with chronic hepatitis C: An international multicenter study, European Journal of Radiology, vol.81, issue.12, pp.4112-4120, 2012.
DOI : 10.1016/j.ejrad.2012.08.018

A. Ferlitsch, P. Salzl, T. Reiberger, M. Homoncik, B. Payer et al., Comparison of liver stiffness assessment by Fibroscan® and Acoustic Radiation Force Impulse Imaging® for the evaluation of liver fibrosis and cirrhosis Disponible sur: https, Z Für Gastroenterol, vol.48, issue.05, 2010.

M. Tanter, J. Bercoff, A. Athanasiou, T. Deffieux, J. Gennisson et al., Quantitative Assessment of Breast Lesion Viscoelasticity: Initial Clinical Results Using Supersonic Shear Imaging, Ultrasound in Medicine & Biology, vol.34, issue.9, pp.1373-86, 2008.
DOI : 10.1016/j.ultrasmedbio.2008.02.002

J. Yoon, J. Lee, J. Han, and B. Choi, Shear Wave Elastography for Liver Stiffness Measurement in Clinical Sonographic Examinations, Journal of Ultrasound in Medicine, vol.46, issue.suppl 8, pp.437-484, 2014.
DOI : 10.7863/ultra.33.3.437

É. Bavu, J. Gennisson, M. Couade, J. Bercoff, V. Mallet et al., Noninvasive In Vivo Liver Fibrosis Evaluation Using Supersonic Shear Imaging: A Clinical Study on 113 Hepatitis C Virus Patients, Ultrasound in Medicine & Biology, vol.37, issue.9, pp.1361-73, 2011.
DOI : 10.1016/j.ultrasmedbio.2011.05.016

C. Cassinotto, B. Lapuyade, A. Mouries, J. Hiriart, J. Vergniol et al., Non-invasive assessment of liver fibrosis with impulse elastography: Comparison of Supersonic Shear Imaging with ARFI and FibroScan??, Journal of Hepatology, vol.61, issue.3, pp.550-557, 2014.
DOI : 10.1016/j.jhep.2014.04.044

G. Ferraioli, C. Tinelli, D. Bello, B. Zicchetti, M. Filice et al., Accuracy of real-time shear wave elastography for assessing liver fibrosis in chronic hepatitis C: A pilot study, Hepatology, vol.344, issue.6, pp.2125-2158, 2012.
DOI : 10.1002/hep.25936

V. Leung, J. Shen, V. Wong, J. Abrigo, G. Wong et al., Quantitative Elastography of Liver Fibrosis and Spleen Stiffness in Chronic Hepatitis B Carriers: Comparison of Shear-Wave Elastography and Transient Elastography with Liver Biopsy Correlation, Radiology, vol.269, issue.3, pp.910-918, 2013.
DOI : 10.1148/radiol.13130128

B. Kastler and D. Vetter, Comprendre l'IRM. Édition : 7e édition. Issy-les-Moulineaux, 2011.

D. Hoa, P. Taourel, A. Micheau, G. Gahide, and E. Bars, L'IRM pas à pas. Montpellier: Sauramps Médical, 2008.

L. Bihan and D. , Looking into the functional architecture of the brain with diffusion MRI, Nature Reviews Neuroscience, vol.4, issue.6, pp.469-80, 2003.
DOI : 10.1038/nrn1119

URL : https://hal.archives-ouvertes.fr/hal-00349696

M. Moseley, Y. Cohen, J. Kucharczyk, J. Mintorovitch, H. Asgari et al., Diffusion-weighted MR imaging of anisotropic water diffusion in cat central nervous system., Radiology, vol.176, issue.2, pp.439-484, 1990.
DOI : 10.1148/radiology.176.2.2367658

E. Stejskal and J. Tanner, Spin Diffusion Measurements: Spin Echoes in the Presence of a Time???Dependent Field Gradient, The Journal of Chemical Physics, vol.42, issue.1, pp.288-92, 1965.
DOI : 10.1063/1.1695690

L. Bihan, D. Breton, E. Lallemand, D. Grenier, P. Cabanis et al., MR imaging of intravoxel incoherent motions: application to diffusion and perfusion in neurologic disorders., Radiology, vol.161, issue.2, pp.401-408, 1986.
DOI : 10.1148/radiology.161.2.3763909

URL : https://hal.archives-ouvertes.fr/hal-00349714

S. Warach, D. Chien, W. Li, M. Ronthal, and R. Edelman, Fast magnetic resonance diffusion-weighted imaging of acute human stroke, Neurology, vol.42, issue.9, pp.1717-1740, 1992.
DOI : 10.1212/WNL.42.9.1717

L. Bihan, D. Breton, E. Lallemand, D. Aubin, M. Vignaud et al., Separation of diffusion and perfusion in intravoxel incoherent motion MR imaging., Radiology, vol.168, issue.2, pp.497-505, 1988.
DOI : 10.1148/radiology.168.2.3393671

URL : https://hal.archives-ouvertes.fr/hal-00349716

L. Bihan, D. Turner, R. Macfall, and J. , Effects of intravoxel incoherent motions (IVIM) in steady-state free precession (SSFP) imaging: application to molecular diffusion imaging, Magnetic Resonance in Medicine, vol.49, issue.3, pp.324-361, 1989.
DOI : 10.1002/mrm.1910100305

URL : https://hal.archives-ouvertes.fr/hal-00349717

L. Bihan, D. Poupon, C. Amadon, A. Lethimonnier, and F. , Artifacts and pitfalls in diffusion MRI, Journal of Magnetic Resonance Imaging, vol.98, issue.12, pp.478-88, 2006.
DOI : 10.1002/jmri.20683

URL : https://hal.archives-ouvertes.fr/hal-00349658

N. Papadakis, K. Martin, J. Pickard, L. Hall, T. Carpenter et al., Gradient preemphasis calibration in diffusion

F. Calamante, D. Porter, D. Gadian, and A. Connelly, Correction for eddy current induced Bo shifts in diffusion-weighted echo-planar imaging, Magnetic Resonance in Medicine, vol.34, issue.1, pp.95-102, 1999.
DOI : 10.1002/(SICI)1522-2594(199901)41:1<95::AID-MRM14>3.0.CO;2-T

R. Ordidge, J. Helpern, Z. Qing, R. Knight, and V. Nagesh, Correction of motional artifacts in diffusion-weighted MR images using navigator echoes, Magnetic Resonance Imaging, vol.12, issue.3, pp.455-60, 1994.
DOI : 10.1016/0730-725X(94)92539-9

J. Burdette, A. Elster, and P. Ricci, Acute Cerebral Infarction: Quantification of Spin-Density and T2 Shine-through Phenomena on Diffusion-weighted MR Images, Radiology, vol.212, issue.2, pp.333-342, 1999.
DOI : 10.1148/radiology.212.2.r99au36333

S. Silvera, C. Oppenheim, E. Touzé, D. Ducreux, P. Page et al., Spontaneous Intracerebral Hematoma on Diffusion-weighted Images: Influence of T2-shine-through and T2-blackout Effects, Am J Neuroradiol. 2 janv, vol.26, issue.2, pp.236-277, 2005.

T. Parikh, S. Drew, V. Lee, S. Wong, E. Hecht et al., Focal Liver Lesion Detection and Characterization with Diffusion-weighted MR Imaging: Comparison with Standard Breath-hold T2-weighted Imaging, Radiology, vol.246, issue.3, pp.812-834, 2008.
DOI : 10.1148/radiol.2463070432

A. Hardie, M. Naik, E. Hecht, H. Chandarana, L. Mannelli et al., Diagnosis of liver metastases: value of diffusion-weighted MRI compared with gadolinium-enhanced MRI, European Radiology, vol.30, issue.955, pp.1431-1472, 2010.
DOI : 10.1007/s00330-009-1695-9

D. Löwenthal, M. Zeile, W. Lim, C. Wybranski, F. Fischbach et al., Detection and characterisation of focal liver lesions in colorectal carcinoma patients: comparison of diffusion-weighted and Gd-EOB-DTPA enhanced MR imaging, European Radiology, vol.200, issue.Suppl 5, pp.832-872, 2011.
DOI : 10.1007/s00330-010-1977-2

M. Bruegel, K. Holzapfel, J. Gaa, K. Woertler, S. Waldt et al., Characterization of focal liver lesions by ADC measurements using a respiratory triggered diffusion-weighted single-shot echo-planar MR imaging technique, European Radiology, vol.24, issue.3, pp.477-85, 2008.
DOI : 10.1007/s00330-007-0785-9

F. Agnello, M. Ronot, D. Valla, R. Sinkus, V. Beers et al., -Value Diffusion-weighted MR Imaging of Benign Hepatocellular Lesions: Quantitative and Qualitative Analysis, Radiology, vol.262, issue.2, pp.511-520, 2012.
DOI : 10.1148/radiol.11110922

URL : https://hal.archives-ouvertes.fr/ujm-01011518

V. Vandecaveye, K. Michielsen, D. Keyzer, F. Laleman, W. Komuta et al., Chemoembolization for Hepatocellular Carcinoma: 1-Month Response Determined with Apparent Diffusion Coefficient Is an Independent Predictor of Outcome, Radiology, vol.270, issue.3, pp.747-57, 2014.
DOI : 10.1148/radiol.13130591

I. Kamel, D. Reyes, E. Liapi, D. Bluemke, and J. Geschwind, Functional MR Imaging Assessment of Tumor Response after 90Y Microsphere Treatment in Patients with Unresectable Hepatocellular Carcinoma, Journal of Vascular and Interventional Radiology, vol.18, issue.1, pp.49-56, 2007.
DOI : 10.1016/j.jvir.2006.10.005

D. Sahani, T. Jiang, K. Hayano, D. Duda, O. Catalano et al., Magnetic resonance imaging biomarkers in hepatocellular carcinoma: association with response and circulating biomarkers after sunitinib therapy, Journal of Hematology & Oncology, vol.6, issue.1, p.51, 2013.
DOI : 10.1200/JCO.2005.02.2574

M. Lewin, L. Fartoux, A. Vignaud, L. Arrivé, Y. Menu et al., The diffusion-weighted imaging perfusion fraction f is a potential marker of sorafenib treatment in advanced hepatocellular carcinoma: a pilot study, European Radiology, vol.30, issue.2, pp.281-90, 2011.
DOI : 10.1007/s00330-010-1914-4

S. Bonekamp, M. Torbenson, and I. Kamel, Diffusion-weighted Magnetic Resonance Imaging for the Staging of Liver Fibrosis, Journal of Clinical Gastroenterology, vol.45, issue.10, pp.885-92, 2011.
DOI : 10.1097/MCG.0b013e318223bd2c

Y. Hong, Y. Shi, W. Liao, N. Klahr, F. Xia et al., Relative ADC measurement for liver fibrosis diagnosis in chronic hepatitis B using spleen/renal cortex as the reference organs at 3??T, Clinical Radiology, vol.69, issue.6, pp.581-589, 2014.
DOI : 10.1016/j.crad.2014.01.004

M. Lewin, A. Poujol-robert, P. Boëlle, D. Wendum, E. Lasnier et al., Diffusion-weighted magnetic resonance imaging for the assessment of fibrosis in chronic hepatitis C, Hepatology, vol.31, issue.3, pp.658-65, 2007.
DOI : 10.1002/hep.21747

L. Annet, F. Peeters, J. Abarca-quinones, I. Leclercq, P. Moulin et al., Assessment of diffusion-weighted MR imaging in liver fibrosis, Journal of Magnetic Resonance Imaging, vol.53, issue.1, pp.122-130, 2007.
DOI : 10.1002/jmri.20771

H. Leitão, S. Doblas, G. Assignies, P. Garteiser, J. Daire et al., Fat deposition decreases diffusion parameters at MRI: a study in phantoms and patients with liver steatosis, European Radiology, vol.31, issue.2, pp.461-468, 2013.
DOI : 10.1007/s00330-012-2626-8

J. Yoon, J. Lee, J. Baek, C. Shin, B. Kiefer et al., Evaluation of Hepatic Fibrosis Using Intravoxel Incoherent Motion in Diffusion-Weighted Liver MRI, Journal of Computer Assisted Tomography, vol.38, issue.1
DOI : 10.1097/RCT.0b013e3182a589be

Y. Wang, D. Ganger, J. Levitsky, L. Sternick, R. Mccarthy et al., Assessment of Chronic Hepatitis and Fibrosis: Comparison of MR Elastography and Diffusion-Weighted Imaging, American Journal of Roentgenology, vol.196, issue.3, pp.553-61, 2011.
DOI : 10.2214/AJR.10.4580

R. Girometti, A. Furlan, G. Esposito, M. Bazzocchi, G. Como et al., -values in evaluating liver fibrosis: A study in healthy and cirrhotic subjects using two single-shot spin-echo echo-planar diffusion-weighted sequences, Journal of Magnetic Resonance Imaging, vol.53, issue.2, pp.411-420, 2008.
DOI : 10.1002/jmri.21461

A. Razek, S. Massoud, M. Azziz, M. El-bendary, K. Zalata et al., Prediction of esophageal varices in cirrhotic patients with apparent diffusion coefficient of the spleen, Abdominal Imaging, vol.68, issue.6, 2015.
DOI : 10.1007/s00261-015-0391-2

H. Bonkovsky, B. Banner, and A. Rothman, Iron and chronic viral hepatitis, Hepatology, vol.25, issue.3, pp.759-68, 1997.
DOI : 10.1002/hep.510250345

M. Barry and S. Sherlock, MEASUREMENT OF LIVER-IRON CONCENTRATION IN NEEDLE-BIOPSY SPECIMENS, The Lancet, vol.297, issue.7690, pp.100-103, 1971.
DOI : 10.1016/S0140-6736(71)90838-5

D. Guyader, Y. Gandon, Y. Deugnier, H. Jouanolle, O. Loreal et al., Evaluation of computed tomography in the assessment of liver iron overload, Gastroenterology, vol.97, issue.3, pp.737-780, 1989.
DOI : 10.1016/0016-5085(89)90646-X

J. Villeneuve, M. Bilodeau, R. Lepage, J. Côté, and M. Lefebvre, Variability in hepatic iron concentration measurement from needle-biopsy specimens, Journal of Hepatology, vol.25, issue.2, pp.172-179, 1996.
DOI : 10.1016/S0168-8278(96)80070-5

C. Rose, P. Vandevenne, E. Bourgeois, N. Cambier, and O. Ernst, Liver iron content assessment by routine and simple magnetic resonance imaging procedure in highly transfused patients, European Journal of Haematology, vol.80, issue.2, pp.145-154, 2006.
DOI : 10.1002/jmri.10332

J. Wood, C. Enriquez, N. Ghugre, J. Tyzka, S. Carson et al., MRI R2 and R2* mapping accurately estimates hepatic iron concentration in transfusion-dependent thalassemia and sickle cell disease patients, Blood, vol.106, issue.4, pp.1460-1465, 2005.
DOI : 10.1182/blood-2004-10-3982

S. Pierre, T. Clark, P. Chua-anusorn, W. Fleming, A. Jeffrey et al., Noninvasive measurement and imaging of liver iron concentrations using proton magnetic resonance, Blood, vol.105, issue.2, pp.855-61, 2005.
DOI : 10.1182/blood-2004-01-0177

A. Tanimoto, K. Oshio, M. Suematsu, D. Pouliquen, and D. Stark, Relaxation effects of clustered particles, Journal of Magnetic Resonance Imaging, vol.174, issue.1, pp.72-79, 2001.
DOI : 10.1002/jmri.1153

J. Hankins, M. Mccarville, R. Loeffler, M. Smeltzer, M. Onciu et al., R2* magnetic resonance imaging of the liver in patients with iron overload, Blood, vol.113, issue.20, pp.4853-4858, 2009.
DOI : 10.1182/blood-2008-12-191643

M. Lazo and J. Clark, The Epidemiology of Nonalcoholic Fatty Liver Disease: A Global Perspective, Seminars in Liver Disease, vol.28, issue.04, pp.339-50, 2008.
DOI : 10.1055/s-0028-1091978

A. Sanyal and A. Gastroenterological-association, AGA technical review on nonalcoholic fatty liver disease, Gastroenterology, vol.123, issue.5, pp.1705-1730, 2002.
DOI : 10.1053/gast.2002.36572

W. Dixon, Simple proton spectroscopic imaging., Radiology, vol.153, issue.1, pp.189-94, 1984.
DOI : 10.1148/radiology.153.1.6089263

M. Fishbein, K. Gardner, C. Potter, P. Schmalbrock, and M. Smith, Introduction of fast MR imaging in the assessment of hepatic steatosis, Magnetic Resonance Imaging, vol.15, issue.3, pp.287-93, 1997.
DOI : 10.1016/S0730-725X(96)00224-X

A. Olthof, P. Sijens, H. Kreeftenberg, P. Kappert, E. Van-der-jagt et al., Non-invasive liver iron concentration measurement by MRI: Comparison of two validated protocols, European Journal of Radiology, vol.71, issue.1, pp.116-137, 2009.
DOI : 10.1016/j.ejrad.2008.02.008

G. Glover and E. Schneider, Three-point dixon technique for true water/fat decomposition withB0 inhomogeneity correction, Magnetic Resonance in Medicine, vol.13, issue.2, pp.371-83, 1991.
DOI : 10.1002/mrm.1910180211

S. Reeder, A. Pineda, Z. Wen, A. Shimakawa, H. Yu et al., Iterative decomposition of water and fat with echo asymmetry and least-squares estimation (IDEAL): Application with fast spin-echo imaging, Magnetic Resonance in Medicine, vol.50, issue.3, pp.636-680, 2005.
DOI : 10.1002/mrm.20624

S. Reeder, C. Mckenzie, A. Pineda, H. Yu, A. Shimakawa et al., Water???fat separation with IDEAL gradient-echo imaging, Journal of Magnetic Resonance Imaging, vol.55, issue.3, pp.644-52, 2007.
DOI : 10.1002/jmri.20831

C. Liu, C. Mckenzie, H. Yu, J. Brittain, and S. Reeder, Fat quantification with IDEAL gradient echo imaging: Correction of bias fromT1 and noise, Magnetic Resonance in Medicine, vol.55, issue.2, pp.354-64, 2007.
DOI : 10.1002/mrm.21301

J. Frahm, H. Bruhn, M. Gyngell, K. Merboldt, W. Hänicke et al., Localized high-resolution proton NMR spectroscopy using stimulated echoes: Initial applications to human brainin vivo, Magnetic Resonance in Medicine, vol.312, issue.1, pp.79-93, 1989.
DOI : 10.1002/mrm.1910090110

P. Bottomley, Spatial Localization in NMR Spectroscopy in Vivo, Annals of the New York Academy of Sciences, vol.160, issue.1 Physiological, pp.333-381, 1987.
DOI : 10.1038/310681a0

P. Sijens, G. Smit, M. Borgdorff, P. Kappert, and M. Oudkerk, Multiple voxel 1H MR spectroscopy of phosphorylase-b kinase deficient patients (GSD IXa) showing an accumulation of fat in the liver that resolves with aging, Journal of Hepatology, vol.45, issue.6, pp.851-856, 2006.
DOI : 10.1016/j.jhep.2006.06.021

L. Szczepaniak, P. Nurenberg, D. Leonard, J. Browning, J. Reingold et al., Magnetic resonance spectroscopy to measure hepatic triglyceride content: prevalence of hepatic steatosis in the general population, AJP: Endocrinology and Metabolism, vol.288, issue.2, pp.462-470, 2005.
DOI : 10.1152/ajpendo.00064.2004

F. Schick, Simultaneous highly selective MR water and fat imaging using a simple new type of spectral-spatial excitation, Magnetic Resonance in Medicine, vol.55, issue.2, pp.194-202, 1998.
DOI : 10.1002/mrm.1910400205

T. Yokoo, M. Bydder, G. Hamilton, M. Middleton, A. Gamst et al., Nonalcoholic Fatty Liver Disease: Diagnostic and Fat-Grading Accuracy of Low-Flip-Angle Multiecho Gradient-Recalled-Echo MR Imaging at 1.5 T, Radiology, vol.251, issue.1, pp.67-76, 2009.
DOI : 10.1148/radiol.2511080666

S. Lee, Y. Lee, N. Kim, S. Kim, J. Byun et al., Hepatic fat quantification using chemical shift MR imaging and MR spectroscopy in the presence of hepatic iron deposition: Validation in phantoms and in patients with chronic liver disease, Journal of Magnetic Resonance Imaging, vol.52, issue.6, pp.1390-1398, 2011.
DOI : 10.1002/jmri.22583

F. Fischbach and H. Bruhn, Assessment of in vivo 1H magnetic resonance spectroscopy in the liver: a review, Liver International, vol.I, issue.3, pp.297-307, 2008.
DOI : 10.1111/j.1478-3231.2007.01647.x

M. Suga, T. Matsuda, K. Minato, O. Oshiro, K. Chihara et al., Measurement of in vivo local shear modulus using MR elastography multiple-phase patchwork offsets, IEEE Transactions on Biomedical Engineering, vol.50, issue.7, pp.908-923, 2003.
DOI : 10.1109/TBME.2003.813540

M. Yin, J. Talwalkar, K. Glaser, A. Manduca, R. Grimm et al., A Preliminary Assessment of Hepatic Fibrosis with Magnetic Resonance Elastography, Clin Gastroenterol Hepatol Off Clin Pract J Am Gastroenterol Assoc. oct, vol.5, issue.10, pp.1207-1220, 2007.

L. Huwart, C. Sempoux, E. Vicaut, N. Salameh, L. Annet et al., Magnetic Resonance Elastography for the Noninvasive Staging of Liver Fibrosis, Gastroenterology, vol.135, issue.1, pp.32-40, 2008.
DOI : 10.1053/j.gastro.2008.03.076

M. Batheja, H. Vargas, A. Silva, F. Walker, Y. Chang et al., Magnetic resonance elastography (MRE) in assessing hepatic fibrosis: performance in a cohort of patients with histological data, Abdominal Imaging, vol.123, issue.3, 2014.
DOI : 10.1007/s00261-014-0321-8

M. Haimerl, N. Verloh, F. Zeman, C. Fellner, R. Müller-wille et al., Assessment of Clinical Signs of Liver Cirrhosis Using T1 Mapping on Gd-EOB-DTPA-Enhanced 3T MRI, PLoS ONE, vol.36, issue.12, p.85658, 2013.
DOI : 10.1371/journal.pone.0085658.t005

F. Smith, J. Mallard, A. Reid, and J. Hutchison, NUCLEAR MAGNETIC RESONANCE TOMOGRAPHIC IMAGING IN LIVER DISEASE, The Lancet, vol.317, issue.8227, pp.963-969, 1981.
DOI : 10.1016/S0140-6736(81)91731-1

A. Alanen, M. Komu, R. Leino, and S. Toikkanen, MR and magnetisation transfer imaging in cirrhotic and fatty livers, Acta Radiol Stockh Swed juill, vol.39, issue.4, pp.434-443, 1987.

Y. Ding, S. Rao, T. Meng, C. Chen, R. Li et al., Usefulness of T1 mapping on Gd-EOB-DTPA-enhanced MR imaging in assessment of non-alcoholic fatty liver disease, European Radiology, vol.51, issue.3, pp.959-66, 2014.
DOI : 10.1007/s00330-014-3096-y

J. Moon, D. Messroghli, P. Kellman, S. Piechnik, M. Robson et al., Myocardial T1 mapping and extracellular volume quantification: a Society for Cardiovascular Magnetic Resonance (SCMR) and CMR Working Group of the European Society of Cardiology consensus statement, Journal of Cardiovascular Magnetic Resonance, vol.15, issue.1, p.92, 2013.
DOI : 10.1186/1532-429X-15-92