R. Inflammatoires and C. , Les rhumatismes inflammatoires chroniques Les RIC concernent près d'un million de français, Les chefs de file de ces pathologies sont la Polyarthrite Rhumatoïde (PR), la SPondylarthrite Ankylosante (SPA) et

R. Haynes, E. Ackloo, and N. Sahota, Interventions for enhancing medication adherence, Cochrane Database Syst Rev. Epub, vol.288, issue.3, p.11, 2008.
DOI : 10.1002/14651858.CD000011.pub2

A. Gadkari and C. Mchorney, Medication nonfulfillment rates and reasons: narrative systematic review. Current medical research and opinion, pp.683-705, 2010.

R. Haynes, H. Mcdonald, and A. Garg, Helping Patients Follow Prescribed Treatment, JAMA, vol.288, issue.22, pp.2880-2883, 2002.
DOI : 10.1001/jama.288.22.2880

E. Goldberg, M. Dekoven, and V. Schabert, Patient medication adherence: the forgotten aspect of biologics, Biotechnology healthcare, vol.6, issue.2, pp.39-4401, 2009.

J. Smolen, D. Aletaha, and M. Koeller, New therapies for treatment of rheumatoid arthritis, The Lancet, vol.370, issue.9602, pp.1861-74, 2007.
DOI : 10.1016/S0140-6736(07)60784-3

C. Bingham, Emerging therapeutics for rheumatoid arthritis Bulletin of the NYU hospital for joint diseases, pp.210-215, 2008.

D. Furst, E. Keystone, and B. Kirkham, Updated consensus statement on biological agents for the treatment of rheumatic diseases, Annals of the rheumatic diseases, vol.67, issue.3, pp.2-25, 2008.

T. Koncz, M. Pentek, and V. Brodszky, Adherence to biologic DMARD therapies in rheumatoid arthritis, Expert Opinion on Biological Therapy, vol.33, issue.2, pp.1367-78, 2010.
DOI : 10.1111/j.1524-4733.2006.00139.x

D. Hughes, W. Cowell, and T. Koncz, Methods for Integrating Medication Compliance and Persistence in Pharmacoeconomic Evaluations, Value in Health, vol.10, issue.6, pp.498-509, 2007.
DOI : 10.1111/j.1524-4733.2007.00205.x

M. Blum, K. D. Doshi, and J. , Measurement and Rates of Persistence With and Adherence to Biologics for Rheumatoid Arthritis: A Systematic Review, Clinical Therapeutics, vol.33, issue.7, pp.901-914, 2011.
DOI : 10.1016/j.clinthera.2011.06.001

A. Williams, E. Manias, and R. Walker, Interventions to improve medication adherence in people with multiple chronic conditions: a systematic review, 12. Les Rhumatismes Inflammatoires Chroniques -AFLAR, pp.132-175, 2008.
DOI : 10.1111/j.1365-2648.2008.04656.x

. Polyarthrite-rhumatoïde-Évolutive-grave and H. Recommandations, Spondylarthrite grave. Recommandations HAS. Décembre 2008:p6. 15, pp.6-14, 2008.

C. L. Backman, Employment and work disability in rheumatoid arthritis, Current Opinion in Rheumatology, vol.16, issue.2, pp.148-52, 2004.
DOI : 10.1097/00002281-200403000-00014

W. N. Burton, A. Morrison, and R. Maclean, Systematic review of studies of productivity loss due to rheumatoid arthritis, Occupational Medicine, vol.56, issue.1, pp.18-27, 2006.
DOI : 10.1093/occmed/kqi171

R. J. Ozminkowski, W. N. Burton, and R. Z. , The Impact of Rheumatoid Arthritis on Medical Expenditures, Absenteeism, and Short-Term Disability Benefits, Journal of Occupational and Environmental Medicine, vol.48, issue.2, pp.135-183, 2006.
DOI : 10.1097/01.jom.0000194161.12923.52

S. Curkendall, V. Patel, and M. Gleeson, Compliance with biologic therapies for rheumatoid arthritis: Do patient out-of-pocket payments matter?, Arthritis & Rheumatism, vol.354, issue.10, pp.1519-1545, 2008.
DOI : 10.1002/art.24114

M. Baudrant, Penser autrement le comportement d'adhésion du patient au traitement médicamenteux, 2009.

C. Tourette-turgis and M. R. , Mettre en place une consultation d'observance aux traitements contre VIH/SIDA, De la théorie à la pratique 2002. 25. Baudrant M, Calop N, Certain A, et al. L'éducation thérapeutique du patient : contexte, concepts et méthodes, pp.1271-87

P. Price, A. Magnan, and D. Vervloet, Diabetes/metabolism research and reviewsCompliance, therapeutic observance and therapeutic adherence: what do we speak about, 2008.

J. Cramer, A. Roy, and A. Burrell, Compliance, observance ou adhesion therapeutique: de quoi parlons-nous? 28 Medication compliance and persistence: terminology and definitions Achaval S, Suarez-Almazor ME. Treatment adherence to disease-modifying antirheumatic drugs in patients with rheumatoid arthritis and systemic lupus erythematosus, Value Health. Epub International journal of clinical rheumatology, vol.115, issue.13, pp.31-444, 2005.

P. Ho, C. Bryson, J. Rumsfeld, X. Huang, and V. Zarotsky, Medication adherence: its importance in cardiovascular outcomes Trends in RA patients' adherence to subcutaneous anti-TNF therapies and costs. Current medical research and opinion, Circulation, vol.11925, issue.236, pp.3028-351365, 2009.

C. Grijalva, C. Chung, and P. Arbogast, Assessment of adherence to and persistence on disease-modifying antirheumatic drugs (DMARDs) in patients with rheumatoid arthritis. Medical care, pp.66-76, 2007.

C. Harley, J. Frytak, and N. Tandon, Treatment compliance and dosage administration among rheumatoid arthritis patients receiving infliximab, etanercept, or methotrexate. The American journal of managed care, pp.136-179, 2003.

P. Choo, C. Rand, and T. Inui, Validation of patient reports, automated pharmacy records, and pill counts with electronic monitoring of adherence to antihypertensive therapy. Medical care, Epub, vol.3724, issue.9, pp.846-57, 1999.

B. Allenet, M. Baudrant, and A. Lehmann, How can we evaluate medication adherence? What are the methods, Annales pharmaceutiques francaises, vol.71, 2013.

D. Morisky, L. Green, D. Levine, X. Girerd, O. Hanon et al., Concurrent and predictive validity of a selfreported measure of medication adherence Epub 1986/01/01. 37Assessment of antihypertensive compliance using a self-administered questionnaire: development and use in a hypertension clinic] Evaluation de l'observance du traitement antihypertenseur par un questionnaire: mise au point et utilisation dans un service specialise. 38. de Klerk E, van der Heijde D, van der Tempel H, et al. Development of a questionnaire to investigate patient compliance with antirheumatic drug therapy Beliefs about medications: a questionnaire survey of people with rheumatoid arthritis, Medical care. Presse Med. Epub The Journal of rheumatology. Rheumatology, vol.243027261244, issue.121126, pp.67-741044, 1986.

M. Baudrant, B. Allenet, L. Tallec, and C. , Educating diabetic children: integrating representations by children aged 7 to 11 and their parents, Pharmacy World & Science, vol.51, issue.3, pp.699-703, 2005.
DOI : 10.1007/s11096-007-9117-z

B. Allenet, A. Guignon, and P. Maire, Intégration des représentations de la personne âgée face à ses médicaments pour améliorer son observance, J Pharm Clin, vol.24, issue.3, pp.175-184, 2005.

H. Leventhal and D. Nerenz, The assessment of illness cognition Measurement strategies in health psychology. Karoly P, editor1985. 517-55 p. 43. IM. R. Historical origins of the Health Belief Model, Health Educ Monogr, vol.2, pp.328-363, 1974.

L. Kristensen, T. Saxne, and J. Nilsson, Impact of concomitant DMARD therapy on adherence to treatment with etanercept and infliximab in rheumatoid arthritis. Results from a six-year observational study in southern Sweden, Arthritis research & therapy. Epub, vol.824, issue.611, p.174, 2006.

R. Horne, D. Buick, and M. Fisher, identifying the types of beliefs that are associated with non-adherence to HAART Phatak HM, Thomas J, 3rd. Relationships between beliefs about medications and nonadherence to prescribed chronic medications. The Annals of pharmacotherapy A psychosocial perspective in the explanation of patients' drug-taking behavior Factors influencing patient decisions about the use of asthma controller medication. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, International journal of STD & AIDS. Soc Sci Med. Asthma, & Immunology, vol.154027983312, issue.4610346, pp.38-441737, 1988.

R. Horne, J. Weinman, M. Hankins, A. Gauchet, and M. Izaute, The Belief about Medicines Questionnaire: The development and evaluation of a new method for assessing the cognitive representation of medication Validation of the French version of the Beliefs about Medicines Questionnaire (BMQ) among diabetes and HIV patients. 2013. 52 Beliefs about medicines in patients with rheumatoid arthritis and systemic lupus erythematosus: a comparison between patients of South Asian and White British origin, Psychology and health. Rheumatology, vol.1447, pp.1-24, 1999.

. Kobe, A glossary of terms for community health care and services for older persons. World Health Organization Sandrin-Berthon B. Education thérapeutique Concepts et enjeux, adsp, vol.5766, pp.10-58, 2004.

F. Bourdillon, Être autorisé à mettre en oeuvre un programme d'éducation thérapeutique : comment? Médecine des maladies Métaboliques, pp.25-30, 2010.

M. Albano, G. Quintrec, J. Crozet, and C. , Characteristics and development of therapeutic patient education in rheumatoid arthritis: analysis of the 2003- 2008 literature. Joint, bone, spine : revue du rhumatisme Influence of patient education on exercise compliance in rheumatoid arthritis: a prospective 12-month randomized controlled trial Outcomes of a rheumatoid arthritis disease therapy management program focusing on medication adherence, The Journal of rheumatology. Epub J Manag Care Pharm, vol.771335121628, issue.628, pp.405-10216, 2007.

B. Allenet, J. Bouchet, L. G. L-'ecole-de-la-polyarthrite-rhumatoïde-de-rhumatologie-du, C. De-grenoble-krishnan, E. Lingala et al., Education Thérapeutique du Patient Modèle, pratiques et évaluation2010 Disability in rheumatoid arthritis in the era of biological treatments Do changes in prescription practice in patients with rheumatoid arthritis treated with biological agents affect treatment response and adherence to therapy? Results from the nationwide Danish DANBIO Registry, Annals of the rheumatic diseases. Annals of the rheumatic diseases, vol.64716715, issue.27, pp.213-81023, 2008.

B. Glintborg, M. Ostergaard, and N. Krogh, Predictors of treatment response and drug continuation in 842 patients with ankylosing spondylitis treated with anti-tumour necrosis factor: results from 8 years' surveillance in the Danish nationwide DANBIO registry Annals of the rheumatic diseases Anti-TNF therapy of ankylosing spondylitis in clinical practice. Results from the Czech national registry ATTRA, Clinical and experimental rheumatology. Rheumatology, vol.692750, issue.116, pp.2002-8958, 2009.

J. Gomez-reino, C. Rodriguez-lozano, and C. Campos-fernandez, Change in the discontinuation pattern of tumour necrosis factor antagonists in rheumatoid arthritis over 10 years: data from the Spanish registry BIOBADASER 2.0, Annals of the Rheumatic Diseases, vol.71, issue.3, pp.382-515, 2010.
DOI : 10.1136/annrheumdis-2011-200302

B. Glintborg, M. Ostergaard, and N. Krogh, Clinical response, drug survival and predictors thereof in 432 ankylosing spondylitis patients after switching tumour necrosis factor alpha inhibitor therapy: results from the Danish nationwide DANBIO registry Annals of the rheumatic diseases Persistence with anti-tumour necrosis factor therapies in patients with psoriatic arthritis: observational study from the British Society of Rheumatology Biologics Register, Arthritis research & therapy, vol.1110, issue.2, p.52, 2009.

C. Duftner, C. Dejaco, and H. Larcher, Biologicals in rheumatology: Austrian experiences from a rheumatic outpatient clinic EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs, Rheumatology international. Annals of the rheumatic diseases, vol.292869, issue.736, pp.69-73964, 2008.

B. Allenet, A. Betegnie, and A. Lehmann, Adherence to biologics in chronic inflammatory rheumatic diseases: identifying levers to better support the patient Comparison between two generic questionnaires to assess satisfaction with medication in chronic diseases, Rheumatology (Oxford) PloS one, vol.826, issue.2, p.5624702, 2013.

S. Garfield, S. Clifford, and L. Eliasson, Suitability of measures of self-reported medication adherence for routine clinical use: a systematic review. BMC medical research methodology, Epub, vol.11, issue.11, p.14905, 2011.

M. Bonafede, K. Fox, and C. Watson, Treatment patterns in the first year after initiating tumor necrosis factor blockers in real-world settings Advances in therapy Factors associated with severe skin infections in patients treated with biologic therapies for inflammatory rheumatic diseases Predictors of adherence to treatment in women with fibromyalgia Comparison of drug retention rates and causes of drug discontinuation between anti-tumor necrosis factor agents in rheumatoid arthritis Understanding compliance issues for daily selfinjectable treatment in ambulatory care settings, M, Garcia Popa-Lisseanu M, et al. Treatment adherence in patients with rheumatoid arthritis and systemic lupus erythematosus, pp.664-7472, 2006.

G. Westhoff and A. Zink, Basic treatment of early rheumatoid arthritis, Zeitschrift f??r Rheumatologie, vol.1051, issue.2, pp.121-125, 2007.
DOI : 10.1007/s00393-007-0153-9

C. Berteau, F. Schwarzenbach, and Y. Donazzolo, Evaluation of performance, safety, subject acceptance, and compliance of a disposable autoinjector for subcutaneous injections in healthy volunteers Need for information and for involvement in decision making among patients with rheumatoid arthritis: a questionnaire survey Medicines adherence: involving patients in decisions about prescribed medicines and supporting adherence -Clinical guidelines, de Klerk E, van der Heijde D, Landewe R, et al. Patient compliance in rheumatoid arthritis, polymyalgia rheumatica, and gout, pp.379-88249, 2003.

H. Brus, M. Van-de-laar, and E. Taal, Determinants of compliance with medication in patients with rheumatoid arthritis: the importance of self-efficacy expectations. Patient education and counseling, Epub, vol.3626, issue.1, pp.57-64, 1999.

P. Li, M. Blum, V. Feldt, and J. , Adherence, Discontinuation, and Switching of Biologic Therapies in Medicaid Enrollees with Rheumatoid Arthritis, Value in Health, vol.13, issue.6, pp.805-817, 2010.
DOI : 10.1111/j.1524-4733.2010.00764.x

G. Popa-lisseanu, M. Greisinger, A. Richardson, and M. , Determinants of treatment adherence in ethnically diverse, economically disadvantaged patients with rheumatic disease, The Journal of rheumatology, vol.32, issue.5, pp.913-922, 2005.

S. Bonino, Vivre la maladie : ces liens qui me rattachent à la vie

D. 'une-manière-générale, ces thérapeutiques m'ont apporté une aide pour diminuer voir arrêter le traitement prescrit par le médecin : Tout à fait