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Master Thesis

Prévention de l’hétéro-agressivité des sujets schizophrènes : efficacité des antipsychotiques de première et de seconde génération

Abstract : Schizophrenia is a common mental illness, causing a strong stigma sometimes linked to aggressive risk conveyed by the media. Although this risk is only slightly increased compared to the general population, some patients may have hetero-aggressive behavior and they must be supported. No treatment has been developed to specifically address this aggressive behavior, but a few studies on our current therapies begin to show interest. Despite this, our practice usually consists in the administration of a first-generation antipsychotic, with the idea that they would be more effective against the aggressiveness of this patients, mainly related to an increase in sedative effect. However, second-generation antipsychotics, neurologically better tolerated and enabling better compliance, could make a treatment of choice in the prevention of aggressiveness from this schizophrenic patients. It is for this purpose that we conducted a literature review of current knowledge about effectiveness of first- and second-generation antipsychotics on this type of behavior. With this knowledge, we then conducted a cross-sectional study from the Buss Perry Aggression Questionnaire, measuring aggressiveness of 331 schizophrenic patients of Expert Center, depending on the received antipsychotic type. The analysis of these two studies allows us to attempt giving treatment recommendations for use with the most violent schizophrenic patients.
Document type :
Master Thesis
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https://dumas.ccsd.cnrs.fr/dumas-01251785
Contributor : Université Paris Descartes - Scd <>
Submitted on : Wednesday, January 6, 2016 - 4:59:11 PM
Last modification on : Friday, March 27, 2020 - 2:18:33 AM
Long-term archiving on: : Thursday, April 7, 2016 - 4:11:25 PM

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  • HAL Id : dumas-01251785, version 1

Citation

Maureen Favez. Prévention de l’hétéro-agressivité des sujets schizophrènes : efficacité des antipsychotiques de première et de seconde génération. Médecine humaine et pathologie. 2015. ⟨dumas-01251785⟩

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