. Etant-donné-qu, il faut 6-12 mois de supplémentation pour retrouver les taux physiologiques de DHEA observés chez un individu jeune [25], il paraît logique que le temps de latence des effets soit supérieur à 3 mois chez 60

. Amélioration-au-niveau-de-la-masse-musculaire, Les résultats de notre étude ne confirment pas l'amélioration de la prise de DHEA sur la masse musculaire

. Amélioration-au-niveau-des-capacités-intellectuelles, Les résultats obtenus laissent penser que la DHEA aurait des propriétés bénéfiques sur la cognition, 60 % des individus parlent d'une efficacité moyenne à très importante contrebalançant le manque de preuves de la littérature à ce sujet

. Parallèlement, les différentes publications se contredisent sur la question

. Toutefois, on peut citer le cas d'une patiente, souffrant de cystites à répétition attribuées à la sécheresse de la muqueuse vaginale, qui suite à la prise de DHEA n'a

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E. E. Baulieu and F. Forette, -Etude de l'administration de déhydroépiandrostérone chez le sujet de 60 à 79 ans ou protocole DHEAge, 2004.
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C. Berr, S. La:-ffont, B. Debuire, J. F. Dartigues, and E. E. Baulieu, -Relationships of dehydroepiandrosterone sulfate in the ederly with functional, psychological, and mental status, and short-term mortality : a french community-based study, Proc. Natl. Acad. Sei, pp.13410-13415, 1996.
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W. Flynn and K. L. Osterholtz, Sharpe Timms-Dehydroepiandrosterone replacement in aging humans, J. Clin. Endocrinol. 1vletab, vol.84, issue.5, pp.1527-1533, 1999.

H. Guénard, Physiologie humaine -2e Ed. -Pradel, Paris-1996

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M. Kalimi and W. Et-regelson, -The biologie role of dehydroépiandrosterone (DHEA)

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V. G. Kimonides, DHEA antagonizes the neurotoxic effect of cortisterone and translocation of stress-actived protein kinase 3 in hippocampal primary cultures - Neuroscience-1999, pp.429-436

F. Labrie, A. Belanger, J. Simard, . Van-luu-the, and C. Labrie, DHEA and Peripheral Androgen and Estrogen Formation: Intracrinology, Annals of the New York Academy of Sciences, vol.12, issue.1 Dehydroepiand, pp.16-28, 1995.
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K. S. Lee and B. C. Kim, Effects of dehydroepiandrosterone on collagen and collagenase gene expression by skin fibroblasts in culture, Journal of Dermatological Science, vol.23, issue.2, pp.103-113, 2000.
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. Ann and . Med, Interne-2001-152, suppl. n°3, pp.1-43

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. T. Wolfü, E. Naumann, D. H. Hellhammer, and C. Kischbaum, -Effects of dehydroepiandrosterone replacement in ederly men: event-related potentials, memory, and well-being, J. Geront. Bio. Med. Sei, vol.53, issue.5, pp.385-390, 1998.
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Y. S. Morales, A. J. Nolan, J. J. Nelson, and J. C. , -Effects ofreplacement dose of dehydroepiandrosterone in men and women of advancing age, J. Clin. Endocrinol. Metab, vol.78, issue.6, pp.1360-1367, 1994.
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S. R. Borken-s, Dehydroepiandrosterone and cardiac arrythmia

D. La and . Déhydroépiandrostérone, stéroïde le plus abondant de l'organisme dont le taux sanguin régresse avec l'âge, est présentée par les médias comme une« hormone miracle» bien que son activité pharmacologique exacte reste mystérieuse et inconnue

. Dans-ce-contexte, quel doit être le rôle du professionnel de santé? Mots clés