A. Sézary and J. Bouvrain, Erythrodermie avec presence de cellules monstrueuses dans le derme et le sang circulant. Bulletin de la Société Francaise de Dermatologie et de Syphiligraphie, pp.245-60, 1938.

H. Taswell and R. Winkelmann, S??zary Syndrome??? A Malignant Reticulemic Erythroderma, JAMA, vol.177, issue.7, pp.465-72, 1961.
DOI : 10.1001/jama.1961.03040330001001

M. Lutzner and H. Jordan, The Ultrastructure of an Abnormal Cell in Sézary's Syndrome. Blood, pp.719-745, 1968.

R. Main, H. Goodall, and W. Swanson, SEZARY'S SYNDROME., British Journal of Dermatology, vol.9, issue.10, pp.335-378, 1959.
DOI : 10.1007/BF01949469

M. Lutzner, I. Emerit, R. Durepaire, G. Flandrin, C. Grupper et al., Cytogenetic, Cytophotometric, and Ultrastructural Study of Large Cerebriform Cells of the S??zary Syndrome and Description of a Small-Cell Variant 2 3, JNCI: Journal of the National Cancer Institute, vol.50, issue.5, pp.1145-62, 1973.
DOI : 10.1093/jnci/50.5.1145

J. Brouet, G. Flandrin, and M. Seligmann, Indications of the Thymus-Derived Nature of the Proliferating Cells in Six Patients with S??zary's Syndrome, New England Journal of Medicine, vol.289, issue.7, pp.341-345, 1973.
DOI : 10.1056/NEJM197308162890703

L. M. , E. R. , S. P. Green-i, K. C. , and A. A. , Cutaneous T-Cell Lymphomas: The Sézary Syndrome, Mycosis Fungoides, and Related Disorders, Ann Intern Med, vol.83, issue.4, pp.534-52, 1975.

S. Lamberg, P. Bunn, and J. , Cutaneous T-Cell Lymphomas, Archives of Dermatology, vol.115, issue.9, pp.1103-1108, 1979.
DOI : 10.1001/archderm.1979.04010090053026

R. Willemze, E. Jaffe, G. Burg, L. Cerroni, E. Berti et al., WHO- EORTC classification for cutaneous lymphomas. Blood, pp.3768-85, 2005.

V. Criscione and M. Weinstock, Incidence of cutaneous T-cell lymphoma in the United States, Arch Dermatol, vol.143, issue.7, pp.854-863, 1973.

E. Jaffe, The 2008 WHO classification of lymphomas: implications for clinical practice and translational research. ASH Educ Program Book, pp.523-554, 2009.

A. Tessier-marteau, L. Corre, Y. Gérard, J. Avenel-audran, M. Geneviève et al., Peripheral blood Sézary cells and the diagnosis of Sézary syndrome], Ann Biol Clin, vol.66, issue.4, pp.447-53, 2008.

M. Suárez-varela, M. , L. González, A. , M. Vila et al., Mycosis fungoides: Review of Epidemiological Observations, Dermatology, vol.201, issue.1, pp.21-29, 2000.
DOI : 10.1159/000018423

H. Wong, Novel biomarkers, dysregulated epigenetics, and therapy in cutaneous T-cell lymphoma, Discov Med, vol.16, issue.87, pp.71-79, 2013.

R. Edelson, Cutaneous T Cell Lymphoma, Annals of the New York Academy of Sciences, vol.91, issue.4, pp.1-11, 2001.
DOI : 10.1111/j.1749-6632.2001.tb03705.x

C. Berger, D. Hanlon, D. Kanada, M. Dhodapkar, V. Lombillo et al., The growth of cutaneous T-cell lymphoma is stimulated by immature dendritic cells. Blood, pp.2929-2968, 2002.

S. Tothova, S. Bonin, G. Trevisan, and G. Stanta, Mycosis fungoides: is it a Borrelia burgdorferi-associated disease? Br J Cancer, Feb, vol.2194, issue.6, pp.879-83, 2006.

J. Abrams, B. Balin, and E. Vonderheid, Association between Sézary T Cellactivating Factor, Chlamydia pneumoniae, and Cutaneous T Cell Lymphoma

J. Abrams, E. Vonderheid, S. Kolbe, D. Appelt, E. Arking et al., Sézary T- Cell Activating Factor Is aChlamydia pneumoniae-Associated Protein, Clin Diagn Lab Immunol, vol.6, issue.6, pp.895-905, 1999.

C. Jackow, J. Cather, V. Hearne, A. Asano, J. Musser et al., Association of Erythrodermic Cutaneous T-Cell Lymphoma, Superantigen-Positive Staphylococcus aureus, and Oligoclonal T-Cell Receptor V? Gene Expansion, Blood, vol.89, issue.1, pp.32-40, 1997.

F. Ballanger, C. Bressollette, C. Volteau, L. Planche, and B. Dreno, Cytomegalovirus: its potential role in the development of cutaneous T-cell lymphoma, Experimental Dermatology, vol.17, issue.6, pp.574-580, 2009.
DOI : 10.1111/j.1600-0625.2008.00817.x

S. Sivori, M. Falco, S. Carlomagno, E. Romeo, C. Soldani et al., A novel KIR-associated function: evidence that CpG DNA uptake and shuttling to early endosomes is mediated by KIR3DL2, Blood, vol.116, issue.10, pp.1637-1684, 2009.
DOI : 10.1182/blood-2009-12-256586

M. Bagot and A. Bensussan, Les lymphomes T épidermotropes comme modèles de progression tumorale. médecine/sciences, Feb, vol.22, issue.2, pp.192-198, 2006.

X. Mao, G. Orchard, D. M. Lillington, F. J. Child, E. C. Vonderheid et al., BCL2 and JUNB abnormalities in primary cutaneous lymphomas, British Journal of Dermatology, vol.22, issue.3, pp.546-56, 2004.
DOI : 10.1046/j.1523-1747.2003.12496.x

M. Su, I. Dorocicz, W. Dragowska, V. Ho, G. Li et al., Aberrant expression of T-plastin in Sezary cells, Cancer Res, vol.63, issue.21, pp.7122-7129, 2003.

L. Tracey, Mycosis fungoides shows concurrent deregulation of multiple genes involved in the TNF signaling pathway: an expression profile study, Blood, vol.102, issue.3, 2003.
DOI : 10.1182/blood-2002-11-3574

M. Bagot, L. Boumsell, and A. Bensussan, Immunopathogenesis of cutaneous T-cell lymphomas, Hematology/Oncology Clinics of North America, vol.17, issue.6, pp.1313-1320, 2003.
DOI : 10.1016/S0889-8588(03)00116-3

M. Bagot and M. Imbert, Syndrome de sézary. Rev Fr Lab, pp.51-57, 2004.

B. Lee, M. Duvic, C. Tang, C. Bueso-ramos, Z. Estrov et al., Dysregulated Synthesis of Intracellular Type 1 and Type 2 Cytokines by T Cells of Patients with Cutaneous T-Cell Lymphoma, Clin Diagn Lab Immunol, 1999.

M. Wysocka, M. Zaki, L. French, J. Chehimi, M. Shapiro et al., Sezary syndrome patients demonstrate a defect in dendritic cell populations: effects of CD40 ligand and treatment with GM-CSF on dendritic cell numbers and the production of cytokines, Blood, vol.100, issue.9, pp.3287-94, 2002.
DOI : 10.1182/blood-2002-01-0231

J. Bouaziz, N. Ortonne, J. Giustiniani, V. Schiavon, D. Huet et al., Circulating Natural Killer Lymphocytes Are Potential Cytotoxic Effectors Against Autologous Malignant Cells in Sezary Syndrome Patients, Journal of Investigative Dermatology, vol.125, issue.6, pp.1273-1281, 2005.
DOI : 10.1111/j.0022-202X.2005.23914.x

H. Echchakir, M. Bagot, G. Dorothée, D. Martinvalet, L. Gouvello et al., Cutaneous T Cell Lymphoma Reactive CD4+ Cytotoxic T Lymphocyte Clones Display a Th1 Cytokine Profile and Use a Fas-Independent Pathway for Specific Tumor Cell Lysis, Journal of Investigative Dermatology, vol.115, issue.1, pp.74-80, 2000.
DOI : 10.1046/j.1523-1747.2000.00995.x

L. Posner, B. Fossieck, J. Eddy, and P. Bunn, Septicemic complications of the cutaneous T-cell lymphomas, The American Journal of Medicine, vol.71, issue.2, pp.210-216, 1981.
DOI : 10.1016/0002-9343(81)90107-8

P. Axelrod, B. Lorber, and E. Vonderheid, Infections Complicating Mycosis Fungoides and S??zary Syndrome, JAMA: The Journal of the American Medical Association, vol.267, issue.10, pp.1354-1362, 1992.
DOI : 10.1001/jama.1992.03480100060031

J. Neel, L. Humbert, and J. Lebrun, Rôle du TGF? dans le cancer chez l'humain: de la suppression tumorale vers le développement des métastases, Med Sci Ameriques, pp.1-18, 2012.

G. Rappl, H. Abken, J. Muche, W. Sterry, W. Tilgen et al., CD4+CD7??? leukemic T cells from patients with S??zary syndrome are protected from galectin-1-triggered T cell death, Leukemia, vol.16, issue.5, pp.840-845, 2002.
DOI : 10.1038/sj.leu.2402438

E. Diamandidou, P. Cohen, and R. Kurzrock, Mycosis fungoides and Sezary syndrome, Blood, vol.88, issue.7, pp.2385-409, 1996.

B. Vowels, M. Cassin, E. Vonderheid, and A. Rook, Aberrant Cytokine Production By Sezary Syndrome Patients: Cytokine Secretion Pattern Resembles Murine Th2 Cells, Journal of Investigative Dermatology, vol.99, issue.1, pp.90-94, 1992.
DOI : 10.1111/1523-1747.ep12611877

B. Chong, A. Wilson, H. Gibson, M. Hafner, Y. Luo et al., Immune Function Abnormalities in Peripheral Blood Mononuclear Cell Cytokine Expression Differentiates Stages of Cutaneous T-Cell Lymphoma/Mycosis Fungoides, Clinical Cancer Research, vol.14, issue.3, pp.646-53, 2008.
DOI : 10.1158/1078-0432.CCR-07-0610

E. Kim, S. Hess, S. Richardson, S. Newton, L. Showe et al., Immunopathogenesis and therapy of cutaneous T cell lymphoma, Journal of Clinical Investigation, vol.115, issue.4, pp.798-812, 2005.
DOI : 10.1172/JCI200524826

M. Bagot, D. Charue, M. L. Boulland, P. Gaulard, J. Revuz et al., Interleukin-7 receptor expression in cutaneous T-cell lymphomas, British Journal of Dermatology, vol.71, issue.4, pp.572-577, 1996.
DOI : 10.1038/332083a0

A. Dalloul, L. Laroche, M. Bagot, M. Mossalayi, C. Fourcade et al., Interleukin-7 is a growth factor for S??zary lymphoma cells., Journal of Clinical Investigation, vol.90, issue.3, pp.1054-60, 1992.
DOI : 10.1172/JCI115920

E. Poszepczynska, M. Bagot, H. Echchakir, D. Martinvalet, M. Ramez et al., Functional characterization of an IL-7?dependent CD4+CD8??+ Th3-type malignant cell line derived from a patient with a cutaneous T-cell lymphoma, Blood, vol.96, issue.3, pp.1056-63, 2000.

E. Bégué, F. Jean-louis, C. Ram-wolff, S. Jauliac, M. Bagot et al., Expression et r??les de la T-plastine dans les lymphomes T cutan??s, Annales de Dermatologie et de V??n??r??ologie, vol.139, issue.12, pp.72-75, 2012.
DOI : 10.1016/j.annder.2012.10.053

J. Campbell, R. Clark, R. Watanabe, and T. Kupper, Sezary syndrome and mycosis fungoides arise from distinct T-cell subsets: a biologic rationale for their distinct clinical behaviors, Blood, vol.116, issue.5, pp.767-71, 2010.
DOI : 10.1182/blood-2009-11-251926

R. Van-doorn, M. Van-kester, R. Dijkman, M. Vermeer, A. Mulder et al., Oncogenomic analysis of mycosis fungoides reveals major differences with Sezary syndrome, Blood, vol.113, issue.1, pp.127-163, 2009.
DOI : 10.1182/blood-2008-04-153031

E. Vonderheid, M. Bernengo, G. Burg, M. Duvic, P. Heald et al., Update on erythrodermic cutaneous T-cell lymphoma: Report of the international society for cutaneous lymphomas, Journal of the American Academy of Dermatology, vol.46, issue.1, pp.95-106, 2002.
DOI : 10.1067/mjd.2002.118538

J. Wieselthier and H. Koh, S??zary syndrome: Diagnosis, prognosis, and critical review of treatment options, Journal of the American Academy of Dermatology, vol.22, issue.3, pp.381-401, 1990.
DOI : 10.1016/0190-9622(90)70054-L

A. Caudron, A. Marie-cardine, A. Bensussan, and M. Bagot, Actualit??s sur le syndrome de S??zary, Annales de dermatologie et de vénéréologie, pp.31-40, 2014.
DOI : 10.1016/j.annder.2011.09.188

E. Olsen, E. Vonderheid, N. Pimpinelli, R. Willemze, Y. Kim et al., Revisions to the staging and classification of mycosis fungoides and Sezary syndrome: a proposal of the International Society for Cutaneous Lymphomas (ISCL) and the cutaneous lymphoma task force of the European Organization of Research and Treatment of Cancer (EORTC), Blood, vol.110, issue.6, pp.1713-1735, 2007.
DOI : 10.1182/blood-2007-03-055749

R. Hoppe, G. Wood, and E. Abel, Mycosis fungoides and the S??zary syndrome: Pathology, staging, and treatment, Current Problems in Cancer, vol.14, issue.6, pp.297-361, 1990.
DOI : 10.1016/0147-0272(90)90018-L

J. Herrmann, H. Roenigk, A. Hurria, T. Kuzel, E. Samuelson et al., Treatment of mycosis fungoides with photochemotherapy (PUVA): Long-term follow-up, Journal of the American Academy of Dermatology, vol.33, issue.2, pp.234-276, 1995.
DOI : 10.1016/0190-9622(95)90241-4

A. Chu, D. Robinson, J. Hawk, R. Meacham, M. Spittle et al., Immunologic Differentiation of the S??zary Syndrome Due to Cutaneous T-Cell Lymphoma and Chronic Actinic Dermatitis, Journal of Investigative Dermatology, vol.86, issue.2, 1986.
DOI : 10.1111/1523-1747.ep12284160

D. 'incan, M. Souteyrand, P. Bignon, Y. Fonck, Y. Roger et al., HYdantoin-induced cutaneous pseudolymphoma with clinical, pathologic, and immunologic aspects of sézary syndrome, Arch Dermatol, vol.128, issue.10, pp.1371-1375, 1992.

N. Ortonne, L. Gouvello, S. Mansour, H. Poillet, C. Martin et al., CD158K/KIR3DL2 Transcript Detection in Lesional Skin of Patients with Erythroderma Is a Tool for the Diagnosis of S??zary Syndrome, Journal of Investigative Dermatology, vol.128, issue.2, pp.465-72, 2008.
DOI : 10.1038/sj.jid.5701013

E. Scheffer, C. Meijer, V. Vloten, W. Willemze, and R. , A histologic study of lymph nodes from patients with the sézary syndrome. Cancer, Jun, vol.1557, issue.12, pp.2375-80, 1986.

R. Winkelmann and J. Linman, Erythroderma with atypical lymphocytes (S??zary syndrome), The American Journal of Medicine, vol.55, issue.2, pp.192-200, 1973.
DOI : 10.1016/0002-9343(73)90168-X

R. Winkelmann, Clinical studies of T-cell erythroderma in the Sezary syndrome, Mayo Clin Proc, vol.49, issue.8, pp.519-544, 1974.

R. Winkelmann and M. Peters, Absolute Number of Circulating S??zary Cells, Archives of Dermatology, vol.117, issue.7, pp.382-382, 1981.
DOI : 10.1001/archderm.1981.01650070006008

G. Schechter, E. Sausville, A. Fischmann, F. Soehnlen, J. Eddy et al., Evaluation of circulating malignant cells provides prognostic information in cutaneous T cell lymphoma, Blood, vol.69, issue.3, pp.841-850, 1987.

R. Willemze, W. Van-vloten, J. Hermans, M. Damsteeg, and C. Meijer, Diagnostic Criteria in S??zary's Syndrome: A Multiparameter Study of Peripheral Blood Lymphocytes in 32 Patients with Erythroderma, Journal of Investigative Dermatology, vol.81, issue.5, 1983.
DOI : 10.1111/1523-1747.ep12521991

R. Willemze, H. Kerl, W. Sterry, E. Berti, L. Cerroni et al., EORTC Classification for Primary Cutaneous Lymphomas: A Proposal From the Cutaneous Lymphoma Study Group of the European Organization for Research and Treatment of Cancer, Blood, vol.90, issue.1, pp.354-71, 1997.

M. Bernengo, M. Novelli, P. Quaglino, F. Lisa, D. Matteis et al., The relevance of the CD4+???CD26- subset in the identification of circulating S??zary cells, British Journal of Dermatology, vol.88, issue.1, pp.125-160, 2001.
DOI : 10.1046/j.1365-2133.2001.04014.x

J. Muche, A. Lukowsky, K. Asadullah, S. Gellrich, and W. Sterry, Demonstration of Frequent Occurrence of Clonal T Cells in the Peripheral Blood of Patients With Primary Cutaneous T-Cell Lymphoma. Blood, pp.1636-1678, 1997.

M. Beylot-barry, O. Dereure, B. Vergier, S. Barete, L. Laroche et al., Prise en charge des lymphomes T cutan??s??: recommandations du Groupe fran??ais d?????tude des lymphomes cutan??s, Annales de Dermatologie et de V??n??r??ologie, vol.137, issue.10, 2010.
DOI : 10.1016/j.annder.2010.06.021

E. Poszepczynska-guigné, V. Schiavon, D. Incan, M. Echchakir, H. Musette et al., CD158k/KIR3DL2 Is a New Phenotypic Marker of Sezary Cells: Relevance for the Diagnosis and Follow-Up of Sezary Syndrome, Journal of Investigative Dermatology, vol.122, issue.3, pp.820-823, 2004.
DOI : 10.1111/j.0022-202X.2004.22326.x

K. Vidulich, R. Talpur, R. Bassett, and M. Duvic, Overall survival in erythrodermic cutaneous T-cell lymphoma: an analysis of prognostic factors in a cohort of patients with erythrodermic cutaneous T-cell lymphoma, International Journal of Dermatology, vol.9, issue.3, pp.243-52, 2009.
DOI : 10.1111/j.1365-4632.2009.03771.x

J. Scarisbrick, S. Whittaker, A. Evans, E. Fraser-andrews, F. Child et al., Prognostic significance of tumor burden in the blood of patients with erythrodermic primary cutaneous T-cell lymphoma, Blood, vol.97, issue.3, pp.624-654, 2001.
DOI : 10.1182/blood.V97.3.624

N. Agar, E. Wedgeworth, S. Crichton, T. Mitchell, M. Cox et al., Survival Outcomes and Prognostic Factors in Mycosis Fungoides/S??zary Syndrome: Validation of the Revised International Society for Cutaneous Lymphomas/European Organisation for Research and Treatment of Cancer Staging Proposal, Journal of Clinical Oncology, vol.28, issue.31, pp.4730-4739, 2010.
DOI : 10.1200/JCO.2009.27.7665

Y. Kim, K. Bishop, A. Varghese, and R. Hoppe, Prognostic Factors in Erythrodermic Mycosis Fungoides and the S??zary Syndrome, Archives of Dermatology, vol.131, issue.9, pp.1003-1011, 1995.
DOI : 10.1001/archderm.1995.01690210033005

E. Tancrède-bohin, M. Ionescu, and P. De-la-salmonière, Prognostic Value of Blood Eosinophilia in Primary Cutaneous T-Cell Lymphomas, Archives of Dermatology, vol.140, issue.9, pp.1057-61, 2004.
DOI : 10.1001/archderm.140.9.1057

M. Bernengo, P. Quaglino, M. Novelli, N. Cappello, G. Doveil et al., Prognostic factors in Sézary syndrome: a multivariate analysis of clinical, haematological and immunological features, Annals of Oncology, vol.9, issue.8, pp.857-63, 1998.
DOI : 10.1023/A:1008397323199

M. Fierro, R. Ponti, S. Titli, L. Bonello, A. Comessatti et al., TCR??-Chain Gene Rearrangement by GeneScan: Incidence and Significance of Clonal Heterogeneity in S??zary Syndrome, Journal of Investigative Dermatology, vol.130, issue.9, pp.2312-2321, 2010.
DOI : 10.1038/jid.2010.97

B. Jr and L. Si, Report of the Committee on Staging and Classification of Cutaneous T-Cell Lymphomas. Cancer Treat Rep, pp.725-733, 1979.

K. Jr, D. Jr, L. Gl, and R. Ma, Erythroderma: review of 82 cases, South Med J, vol.79, issue.10, pp.1210-1215, 1986.

J. Despain and D. Clark, Subacute cutaneous lupus erythematosus presenting as erythroderma, Journal of the American Academy of Dermatology, vol.19, issue.2, pp.388-92, 1988.
DOI : 10.1016/S0190-9622(88)70184-X

S. Duncan and R. Winkelmann, Circulating Sezary cells in hospitalized dermatology patients, British Journal of Dermatology, vol.49, issue.2, pp.171-179, 1978.
DOI : 10.1001/archderm.111.1.29

O. Briain, D. Lawlor, E. Sarsfield, P. Cooney, C. Blaney et al., Circulating cerebriform lymphoid cells (sezary-type cells) in a b-cell malignant lymphoma. Cancer, pp.1587-93, 1988.

J. Toonstra, C. Henquet, H. Van-weelden, S. Van-der-putte, and W. Van-vloten, Actinic reticuloid, Journal of the American Academy of Dermatology, vol.21, issue.2, pp.205-219, 1989.
DOI : 10.1016/S0190-9622(89)70162-6

J. Toonstra, A. Wildschut, J. Boer, G. Smeenk, R. Willemze et al., Jessner's lymphocytic infiltration of the skin. A clinical study of 100 patients, Archives of Dermatology, vol.125, issue.11, pp.1525-1555, 1989.
DOI : 10.1001/archderm.125.11.1525

Y. Bignon, P. Souteyrand, W. Van-vloten, R. Willemze, L. Vejlsgaard et al., Genotyping of Cutaneous T-Cell Lymphomas and Pseudolymphomas, Current Problems in Dermatology [Internet]. S. Karger AG, pp.114-137, 1989.
DOI : 10.1159/000418081

U. Rijlaarsdam and R. Willemze, Cutaneous pseudo-T-cell lymphomas, Semin Diagn Pathol, vol.8, issue.2, pp.102-110, 1991.

J. Rijlaarsdam, E. Scheffer, C. Meijer, and R. Willemze, Cutaneous pseudo-T-cell lymphomas. A clinicopathologic study of 20 patients. Cancer, Feb, vol.169, issue.3, pp.717-741, 1992.

W. Lambert and M. Everett, The nosology of parapsoriasis, Journal of the American Academy of Dermatology, vol.5, issue.4, pp.373-95, 1981.
DOI : 10.1016/S0190-9622(81)70100-2

M. Lindae, E. Abel, R. Hoppe, and G. Wood, Poikilodermatous Mycosis Fungoides and Atrophic Large-Plaque Parapsoriasis Exhibit Similar Abnormalities of T-Cell Antigen Expression, Archives of Dermatology, vol.124, issue.3, pp.366-72, 1988.
DOI : 10.1001/archderm.1988.01670030032018

W. Macaulay, Lymphomatoid papulosis. A continuing self-healing eruption, clinically benign--histologically malignant, Archives of Dermatology, vol.97, issue.1, pp.23-30, 1968.
DOI : 10.1001/archderm.97.1.23

R. Willemze, C. Meyer, V. Vloten, W. Scheffer, and E. , The clinical and histological spectrum of lymphomatoid papulosis, British Journal of Dermatology, vol.1, issue.2, pp.131-175, 1982.
DOI : 10.1007/BF00709158

F. Cabanillas, J. Armitage, W. Pugh, D. Weisenburger, and M. Duvic, Lymphomatoid Papulosis: A T-Cell Dyscrasia with a Propensity To Transform into Malignant Lymphoma, Annals of Internal Medicine, vol.122, issue.3, pp.210-217, 1995.
DOI : 10.7326/0003-4819-122-3-199502010-00009

H. Pinkus, Alopecia Mucinosa, A.M.A. Archives of Dermatology, vol.76, issue.4, pp.419-443, 1957.
DOI : 10.1001/archderm.1957.01550220027005

H. Plotnick and M. Abbrecht, Alopecia mucinosa and lymphoma. Report of two cases and review of literature, Archives of Dermatology, vol.92, issue.2, pp.137-178, 1965.
DOI : 10.1001/archderm.92.2.137

A. Binnick, F. Wax, and W. Clendenning, Alopecia Mucinosa of the Face Associated With Mycosis Fungoides, Archives of Dermatology, vol.114, issue.5, pp.791-793, 1978.
DOI : 10.1001/archderm.1978.01640170087021

W. Wood, V. Killby, and W. Stewart, Pagetoid Reticulosis. (Woringer-Kolopp Disease), Journal of Cutaneous Pathology, vol.10, issue.2, pp.113-136, 1979.
DOI : 10.1001/archderm.114.2.262

J. Lacour, L. Juhlin, P. Baze, . El, M. Barety et al., Disseminated pagetoid reticulosis associated with mycosis fungoides: Immunomorphologic study, Journal of the American Academy of Dermatology, vol.14, issue.5, pp.898-901, 1986.
DOI : 10.1016/S0190-9622(86)70107-2

V. Mielke, H. Wolff, M. Winzer, and W. Sterry, Localized and disseminated pagetoid reticulosis. Diagnostic immunophenotypical findings, Archives of Dermatology, vol.125, issue.3, pp.402-408, 1989.
DOI : 10.1001/archderm.125.3.402

P. Leboit, J. Beckstead, B. Bond, W. Epstein, I. Frieden et al., Granulomatous slack skin, J Invest Dermatol, vol.89, issue.2, pp.183-189, 1987.
DOI : 10.1007/978-3-642-57624-9_13

R. Beljaards, P. Kaudewitz, E. Berti, R. Gianotti, C. Neumann et al., Primary cutaneous CD30-positive large cell lymphoma: Definition of a new type of cutaneous lymphoma with a favorable prognosis.A European multicenter study of 47 patients, Cancer, vol.19, issue.6, pp.2097-104, 1993.
DOI : 10.1002/1097-0142(19930315)71:6<2097::AID-CNCR2820710626>3.0.CO;2-7

T. Uchiyama, J. Yodoi, K. Sagawa, K. Takatsuki, and H. Uchino, Adult T-cell leukemia, Blood Reviews, vol.2, issue.4, pp.481-92, 1977.
DOI : 10.1016/0268-960X(88)90012-4

S. Horwitz, E. Olsen, M. Duvic, P. Porcu, and Y. Kim, Review of the Treatment of Mycosis Fungoides and Sézary Syndrome: A Stage-Based Approach, J Natl Compr Canc Netw, vol.6, issue.4, pp.436-478, 2008.

S. Dugas-breit, H. Schulze, and C. Hallermann, New and established treatment options for mycosis fungoides and S??zary syndrome - an update, JDDG: Journal der Deutschen Dermatologischen Gesellschaft, vol.120, issue.11, pp.561-570
DOI : 10.1111/ddg.12376

C. Pitzalis, N. Pipitone, and M. Perretti, Regulation of Leukocyte-Endothelial Interactions by Glucocorticoids, Annals of the New York Academy of Sciences, vol.86, issue.1, pp.108-126, 2002.
DOI : 10.1111/j.1749-6632.2002.tb04208.x

P. Barnes and K. M. , Nuclear Factor-?B ? A Pivotal Transcription Factor in Chronic Inflammatory Diseases, N Engl J Med Apr, vol.10336, issue.15, pp.1066-71, 1997.

L. M. Lindahl, M. Fenger-grøn, and L. Iversen, Secondary cancers, comorbidities and mortality associated with nitrogen mustard therapy in patients with mycosis fungoides: a 30-year population-based cohort study, British Journal of Dermatology, vol.74, issue.3, pp.699-704, 2014.
DOI : 10.1111/bjd.12620

Y. Kim, G. Martinez, A. Varghese, and R. Hoppe, Topical Nitrogen Mustard in the Management of Mycosis Fungoides, Archives of Dermatology, vol.139, issue.2, pp.165-73, 2003.
DOI : 10.1001/archderm.139.2.165

R. A. Abbott, S. J. Whittaker, S. L. Morris, R. Russell-jones, T. Hung et al., Bexarotene therapy for mycosis fungoides and S??zary syndrome, British Journal of Dermatology, vol.104, issue.6, pp.1299-307, 2009.
DOI : 10.1111/j.1365-2133.2009.09037.x

J. Budgin, S. Richardson, and S. Newton, Biological Effects of Bexarotene in Cutaneous T-Cell Lymphoma, Archives of Dermatology, vol.141, issue.3, pp.315-335, 2005.
DOI : 10.1001/archderm.141.3.315

S. Richardson, S. Newton, T. Bach, J. Budgin, B. Benoit et al., Bexarotene blunts malignant T-cell chemotaxis in Sezary syndrome: Reduction of chemokine receptor 4-positive lymphocytes and decreased chemotaxis to thymus and activation-regulated chemokine, American Journal of Hematology, vol.10, issue.9, pp.792-799, 2007.
DOI : 10.1002/ajh.20952

A. Farkas, L. Kemeny, L. French, and R. Dummer, New and Experimental Skin-Directed Therapies for Cutaneous Lymphomas, Skin Pharmacology and Physiology, vol.22, issue.6, pp.322-356, 2009.
DOI : 10.1159/000241302

H. Zackheim, Topical carmustine (BCNU) in the treatment of mycosis fungoides, Dermatologic Therapy, vol.42, issue.4, pp.299-302, 2003.
DOI : 10.1001/archderm.106.2.177

C. Pressanti and M. Cadiergues, Mécanismes d'action de l'imiquimod et implication dans le traitement des affections cutanées virales humaines et animales. Prat Médicale Chir Anim Cie, pp.105-117, 2013.

D. Hurwitz, L. Pincus, and T. Kupper, Imiquimod, Archives of Dermatology, vol.139, issue.10, pp.1347-50, 2003.
DOI : 10.1001/archderm.139.10.1347

S. Arulogun, H. Prince, P. Gambell, S. Lade, G. Ryan et al., Extracorporeal photopheresis for the treatment of S??zary syndrome using a novel treatment protocol, Journal of the American Academy of Dermatology, vol.59, issue.4, pp.589-95, 2008.
DOI : 10.1016/j.jaad.2008.05.038

K. Camphausen and P. Tofilon, Inhibition of Histone Deacetylation: A Strategy for Tumor Radiosensitization, Journal of Clinical Oncology, vol.25, issue.26, pp.4051-4057, 2007.
DOI : 10.1200/JCO.2007.11.6202

D. Parida, K. Verma, S. Chander, R. Joshi, and G. Rath, Total skin electron irradiation therapy in mycosis fungoides using high-dose rate mode: A preliminary experience, International Journal of Dermatology, vol.15, issue.0, pp.828-858, 2005.
DOI : 10.1016/S0360-3016(97)00585-3

G. Jones, B. Kacinski, L. Wilson, R. Willemze, M. Spittle et al., Total skin electron radiation in the management of mycosis fungoides: Consensus of the European Organization for Research and Treatment of Cancer (EORTC) Cutaneous Lymphoma Project Group, Journal of the American Academy of Dermatology, vol.47, issue.3, pp.364-70, 2002.
DOI : 10.1067/mjd.2002.123482

O. Ea and P. B. , Interferon in the treatment of cutaneous T-cell lymphoma, Hematol Oncol Clin North Am, vol.9, issue.5, pp.1089-107, 1995.

C. Querfeld, N. Mehta, S. Rosen, J. Guitart, A. Rademaker et al., Alemtuzumab for relapsed and refractory erythrodermic cutaneous T-cell lymphoma: a single institution experience from the Robert H. Lurie Comprehensive Cancer Center, Leukemia & Lymphoma, vol.90, issue.12, pp.1969-76, 2009.
DOI : 10.1046/j.1523-1747.2003.12402.x

Y. Kim, M. Duvic, E. Obitz, R. Gniadecki, L. Iversen et al., Clinical efficacy of zanolimumab (HuMax-CD4): two phase 2 studies in refractory cutaneous T-cell lymphoma, Blood, vol.109, issue.11, pp.4655-62, 2007.
DOI : 10.1182/blood-2006-12-062877

M. Ogura, T. Ishida, K. Hatake, M. Taniwaki, K. Ando et al., Multicenter Phase II Study of Mogamulizumab (KW-0761), a Defucosylated Anti-CC Chemokine Receptor 4 Antibody, in Patients With Relapsed Peripheral T-Cell Lymphoma and Cutaneous T-Cell Lymphoma, Journal of Clinical Oncology, vol.32, issue.11, pp.1157-63, 2014.
DOI : 10.1200/JCO.2013.52.0924

E. Olsen, Y. Kim, T. Kuzel, T. Pacheco, F. Foss et al., Phase IIB Multicenter Trial of Vorinostat in Patients With Persistent, Progressive, or Treatment Refractory Cutaneous T-Cell Lymphoma, Journal of Clinical Oncology, vol.25, issue.21, pp.3109-3124, 2007.
DOI : 10.1200/JCO.2006.10.2434

H. Zackheim, M. Kashani-sabet, and A. Mcmillan, Low-dose methotrexate to treat mycosis fungoides: a retrospective study in 69 patients, Journal of the American Academy of Dermatology, vol.49, issue.5, pp.873-881, 2003.
DOI : 10.1016/S0190-9622(03)01591-3

Y. Hui and J. Reitz, Gemcitabine: a cytidine analogue active against solid tumors. Am J Health-Syst Pharm AJHP Off J Am Soc Health-Syst Pharm, pp.162-70, 1997.

K. Jidar, S. Ingen-housz-oro, M. Beylot-barry, C. Paul, D. Chaoui et al., Gemcitabine treatment in cutaneous T-cell lymphoma: a multicentre study of 23 cases, British Journal of Dermatology, vol.31, issue.3, pp.660-663, 2009.
DOI : 10.1111/j.1365-2133.2009.09230.x

C. Assaf, J. Becker, M. Beyer, A. Cozzio, E. Dippel et al., Treatment of advanced cutaneous T-cell lymphomas with non-pegylated liposomal doxorubicin - Consensus of the lymphoma group of the Working Group Dermatologic Oncology, JDDG: Journal der Deutschen Dermatologischen Gesellschaft, vol.24, issue.5, 2013.
DOI : 10.1111/ddg.12012

K. Kahata, S. Hashino, M. Takahata, F. Fujisawa, T. Kondo et al., Durable Remission of S&eacute;zary Syndrome after Unrelated Bone Marrow Transplantation by Reduced-Intensity Conditioning, Acta Haematologica, vol.120, issue.1, pp.14-22, 2008.
DOI : 10.1159/000151510

R. Duarte, C. Canals, F. Onida, I. Gabriel, R. Arranz et al., Allogeneic Hematopoietic Cell Transplantation for Patients With Mycosis Fungoides and S??zary Syndrome: A Retrospective Analysis of the Lymphoma Working Party of the European Group for Blood and Marrow Transplantation, Journal of Clinical Oncology, vol.28, issue.29, pp.4492-4501, 2010.
DOI : 10.1200/JCO.2010.29.3241

H. Jouault and M. Imbert, La cytométrie en flux: intérêt et applications en hématologie. Rev Fr Lab, pp.29-35, 1995.

M. Bagot, J. Civatte, I. Binet, M. Tubiana, and Y. Bouvrain, Le lymphome cutané de type Sézary et Bouvrain, Progrès physiopathologiques et perspectives thérapeutiques, pp.927-965, 1998.

L. Boumsell, A. Bernard, E. Reinherz, L. Nadler, J. Ritz et al., Surface antigens on malignant Sezary and T-CLL cells correspond to those of mature T cells, Blood, vol.57, issue.3, pp.526-556, 1981.

C. Harmon, T. Witzig, J. Katzmann, and M. Pittelkow, Detection of circulating T cells with CD4+CD7??? immunophenotype in patients with benign and malignant lymphoproliferative dermatoses, Journal of the American Academy of Dermatology, vol.35, issue.3, pp.404-414, 1996.
DOI : 10.1016/S0190-9622(96)90605-2

W. Gorczyca, Differential Diagnosis of T-Cell Lymphoproliferative Disorders by Flow Cytometry Multicolor Immunophenotyping. Correlation with Morphology, Methods Cell Biol, vol.75, pp.595-621, 2004.
DOI : 10.1016/S0091-679X(04)75025-6

L. Ginaldi, N. Farahat, E. Matutes, M. Martinis, R. Morilla et al., Differential expression of T cell antigens in normal peripheral blood lymphocytes: a quantitative analysis by flow cytometry., Journal of Clinical Pathology, vol.49, issue.7, pp.539-583, 1996.
DOI : 10.1136/jcp.49.7.539

B. Laetsch, A. Häffner, U. Döbbeling, B. Seifert, E. Ludwig et al., CD4+/CD7??? T Cell Frequency and Polymerase Chain Reaction-Based Clonality Assay Correlate with Stage in Cutaneous T Cell Lymphomas, Journal of Investigative Dermatology, vol.114, issue.1, pp.107-118, 2000.
DOI : 10.1046/j.1523-1747.2000.00818.x

U. Reinhold, H. Abken, S. Kukel, M. Moll, R. Müller et al., CD7-T cells represent a subset of normal human blood lymphocytes, J Immunol, vol.150, issue.5, pp.2081-2090, 1993.

R. Stillwell and B. Bierer, T Cell Signal Transduction and the Role of CD7 in Costimulation, Immunologic Research, vol.24, issue.1, pp.31-52, 2001.
DOI : 10.1385/IR:24:1:31

A. Hristov, E. Vonderheid, and M. Borowitz, Simplified Flow Cytometric Assessment in Mycosis Fungoides and Sezary Syndrome, American Journal of Clinical Pathology, vol.136, issue.6, 2011.
DOI : 10.1309/AJCP09OTJOYAVZZK

S. Kukel, U. Reinhold, I. Oltermann, and H. Kreysel, Progressive increase of CD7- T cells in human blood lymphocytes with ageing, Clinical & Experimental Immunology, vol.149, issue.1, pp.163-171, 1994.
DOI : 10.1111/j.1365-2249.1994.tb06624.x

M. Moll, U. Reinhold, S. Kukel, H. Abken, R. Müller et al., CD7-Negative Helper T Cells Accumulate in Inflammatory Skin Lesions, Journal of Investigative Dermatology, vol.102, issue.3, pp.328-360, 1994.
DOI : 10.1111/1523-1747.ep12371791

L. Jung, S. Fu, T. Hara, N. Kapoor, and R. Good, Defective expression of T cell-associated glycoprotein in severe combined immunodeficiency., Journal of Clinical Investigation, vol.77, issue.3, pp.940-946, 1986.
DOI : 10.1172/JCI112393

B. Sa, D. P. , M. C. , M. M. , H. K. et al., Immunophenotypic identification of Sezary cells in peripheral blood, Am J Clin Pathol, vol.106, issue.6, pp.739-787, 1996.

V. Schiavon, P. Roth, W. Bolton, J. Farcet, A. Bensussan et al., Lymphocytes subsets in normal individuals: analysis by four color immunofluorescence and flow cytometry on whole blood, Tissue Antigens, vol.79, issue.4, pp.312-320, 1996.
DOI : 10.1111/j.1399-0039.1996.tb02650.x

M. Narducci, E. Scala, A. Bresin, E. Caprini, M. Picchio et al., Skin homing of Sezary cells involves SDF-1-CXCR4 signaling and down-regulation of CD26/dipeptidylpeptidase IV, Blood, vol.107, issue.3, pp.1108-1123, 2006.
DOI : 10.1182/blood-2005-04-1492

T. Mattern, W. Scholz, A. Feller, H. Flad, and A. Ulmer, Expression of CD26 (Dipeptidyl Peptidase IV) on Resting and Activated Human T-Lymphocytes, Scandinavian Journal of Immunology, vol.31, issue.97
DOI : 10.1016/0008-8749(85)90400-9

M. Girardi, P. Heald, and L. Wilson, The Pathogenesis of Mycosis Fungoides, New England Journal of Medicine, vol.350, issue.19, pp.1978-88, 2004.
DOI : 10.1056/NEJMra032810

A. Lambeir, P. Proost, C. Durinx, G. Bal, K. Senten et al., Kinetic Investigation of Chemokine Truncation by CD26/Dipeptidyl Peptidase IV Reveals a Striking Selectivity within the Chemokine Family, Journal of Biological Chemistry, vol.276, issue.32, 2001.
DOI : 10.1074/jbc.M103106200

K. Ohnuma, N. Takahashi, T. Yamochi, O. Hosono, N. Dang et al., Role of CD26/dipeptidyl peptidase IV in human T cell activation and function, Frontiers in Bioscience, vol.13, issue.13, pp.2299-310, 2008.
DOI : 10.2741/2844

P. Havre, M. Abe, Y. Urasaki, K. Ohnuma, C. Morimoto et al., The role of CD26/dipeptidyl peptidase IV in cancer, Frontiers in Bioscience, vol.13, issue.13, pp.1634-1679, 2008.
DOI : 10.2741/2787

N. Dang, Y. Torimoto, K. Shimamura, T. Tanaka, J. Daley et al., 1F7 (CD26): a marker of thymic maturation involved in the differential regulation of the CD3 and CD2 pathways of human thymocyte activation, J Immunol, vol.147, issue.9, pp.2825-2857, 1991.

A. Carbone, M. Cozzi, A. Gloghini, and A. Pinto, CD26/dipeptidyl peptidase IV expression in human lymphomas is restricted to CD30-positive anaplastic large cell and a subset of T-cell non-Hodgkin's lymphomas, Human Pathology, vol.25, issue.12, 1994.
DOI : 10.1016/0046-8177(94)90098-1

D. Jones, N. Dang, M. Duvic, L. Washington, and Y. Huh, Absence of CD26 Expression Is a Useful Marker for Diagnosis of T-Cell Lymphoma in Peripheral Blood, American Journal of Clinical Pathology, vol.115, issue.6, pp.885-92, 2001.
DOI : 10.1309/U1Y6-J4AG-5M4M-7AYV

D. Pende, R. Biassoni, C. Cantoni, S. Verdiani, M. Falco et al., The natural killer cell receptor specific for HLA-A allotypes: a novel member of the p58/p70 family of inhibitory receptors that is characterized by three immunoglobulin-like domains and is expressed as a 140-kD disulphide-linked dimer, Journal of Experimental Medicine, vol.184, issue.2, pp.505-523, 1996.
DOI : 10.1084/jem.184.2.505

N. Ortonne, D. Huet, C. Gaudez, A. Marie-cardine, V. Schiavon et al., Significance of circulating T-cell clones in Sezary syndrome, Blood, vol.107, issue.10, pp.4030-4038, 2006.
DOI : 10.1182/blood-2005-10-4239

A. Moretta, R. Biassoni, C. Bottino, D. Pende, M. Vitale et al., Major histocompatibility complex class I-specific receptors on human natural killer and T lymphocytes, Immunological Reviews, vol.154, issue.1, pp.105-122, 1997.
DOI : 10.1006/clin.1994.1029

C. Gardiner, L. Guethlein, H. Shilling, M. Pando, W. Carr et al., Different NK Cell Surface Phenotypes Defined by the DX9 Antibody Are Due to KIR3DL1 Gene Polymorphism, The Journal of Immunology, vol.166, issue.5, pp.2992-3001, 2001.
DOI : 10.4049/jimmunol.166.5.2992

M. Mingari, A. Moretta, and L. Moretta, Regulation of KIR expression in human T cells: a safety mechanism that may impair protective T-cell responses, Immunology Today, vol.19, issue.4, pp.153-160, 1998.
DOI : 10.1016/S0167-5699(97)01236-X

E. Vivier and N. Anfossi, Inhibitory NK-cell receptors on T cells: witness of the past, actors of the future, Nature Reviews Immunology, vol.170, issue.3, pp.190-198, 2004.
DOI : 10.1038/nri1306

D. Bahler, L. Hartung, S. Hill, G. Bowen, and E. Vonderheid, CD158k/KIR3DL2 is a useful marker for identifying neoplastic T-cells in S??zary syndrome by flow cytometry, Cytometry Part B: Clinical Cytometry, vol.4, issue.3, pp.156-62, 2008.
DOI : 10.1002/cyto.b.20395

J. Bouaziz, N. Remtoula, A. Bensussan, A. Marie-cardine, and M. Bagot, Absolute CD3+ CD158k+ lymphocyte count is reliable and more sensitive than 98

J. Wechsler, M. Bagot, M. Nikolova, S. Parolini, N. Martin-garcia et al., S??zary syndrome lymphocytes, The Journal of Pathology, vol.36, issue.1, pp.77-83, 2003.
DOI : 10.1002/path.1251

E. Vonderheid, On the diagnosis of erythrodermic cutaneous T-cell lymphoma, Journal of Cutaneous Pathology, vol.132, issue.2, pp.27-42, 2006.
DOI : 10.1038/sj.leu.2400710

M. Delfau-larue, S. Dalac, E. Lepage, T. Petrella, J. Wechsler et al., Prognostic Significance of a Polymerase Chain Reaction?Detectable Dominant T-Lymphocyte Clone in Cutaneous Lesions of Patients With Mycosis Fungoides, Blood, vol.92, issue.9, pp.3376-80, 1998.

M. Delfau-larue, L. Laroche, J. Wechsler, E. Lepage, C. Lahet et al., Diagnostic value of dominant T-cell clones in peripheral blood in 363 patients presenting consecutively with a clinical suspicion of cutaneous lymphoma, Blood, vol.96, issue.9, pp.2987-92, 2000.

M. Beylot-barry, V. Sibaud, R. Thiebaut, B. Vergier, C. Beylot et al., Evidence that an Identical T Cell Clone in Skin and Peripheral Blood Lymphocytes is an Independent Prognostic Factor in Primary Cutaneous T Cell Lymphomas, Journal of Investigative Dermatology, vol.117, issue.4, pp.920-926, 2001.
DOI : 10.1046/j.0022-202x.2001.01476.x

C. Klemke, J. Brade, S. Weckesser, M. Sachse, N. Booken et al., The diagnosis of S??zary syndrome on peripheral blood by flow cytometry requires the use of multiple markers, British Journal of Dermatology, vol.22, issue.Suppl. 1, pp.871-80, 2008.
DOI : 10.1111/j.1365-2133.2008.08739.x

B. Feng, J. Jorgensen, D. Jones, S. Chen, Y. Hu et al., Flow cytometric detection of peripheral blood involvement by mycosis fungoides and Sézary syndrome using T-cell receptor Vbeta chain antibodies and its application in blood staging, Mod Pathol Off J U S Can Acad Pathol Inc, 2010.

M. Thangavelu, W. Finn, K. Yelavarthi, H. Roenigk, E. Samuelson et al., Recurring structural chromosome abnormalities in peripheral blood lymphocytes of patients with mycosis fungoides/Sézary syndrome, Blood, vol.89, issue.9, pp.3371-3378, 1997.

G. Burg, W. Kempf, A. Cozzio, J. Feit, R. Willemze et al., WHO/EORTC classification of cutaneous lymphomas 2005: histological and molecular aspects, Journal of Cutaneous Pathology, vol.35, issue.10, pp.647-74, 2005.
DOI : 10.1002/cncr.10489.abs

X. Mao, D. Lillington, B. Czepulkowski, R. , R. Young et al., Molecular cytogenetic characterization of S??zary syndrome, Genes, Chromosomes and Cancer, vol.20, issue.3, pp.250-60, 2003.
DOI : 10.1002/gcc.10152

M. Vermeer, R. Van-doorn, R. Dijkman, X. Mao, S. Whittaker et al., Novel and Highly Recurrent Chromosomal Alterations in Sezary Syndrome, Cancer Research, vol.68, issue.8, pp.2689-98, 2008.
DOI : 10.1158/0008-5472.CAN-07-6398

M. Nielsen, C. Kaestel, K. Eriksen, A. Woetmann, T. Stokkedal et al., Inhibition of constitutively activated Stat3 correlates with altered Bcl-2/Bax expression and induction of apoptosis in mycosis fungoides tumor cells, Leukemia, vol.13, issue.5, pp.735-743, 1999.
DOI : 10.1038/sj.leu.2401415

Q. Zhang, STAT3 induces transcription of the DNA methyltransferase 1 gene (DNMT1) in malignant T lymphocytes, Blood, vol.108, issue.3, pp.1058-64, 2006.
DOI : 10.1182/blood-2005-08-007377

E. Ballabio, T. Mitchell, M. Van-kester, S. Taylor, H. Dunlop et al., MicroRNA expression in Sezary syndrome: identification, function, and diagnostic potential, Blood, vol.116, issue.7, pp.1105-1118, 2010.
DOI : 10.1182/blood-2009-12-256719

C. Querfeld, S. Rosen, J. Guitart, and T. Kuzel, The spectrum of cutaneous T-cell lymphomas: new insights into biology and therapy, Current Opinion in Hematology, vol.12, issue.4, 2005.
DOI : 10.1097/01.moh.0000166498.64515.03

E. Sausville, J. Eddy, R. Makuch, A. Fischmann, G. Schechter et al., Histopathologic Staging at Initial Diagnosis of Mycosis Fungoides and the S??zary Syndrome, Annals of Internal Medicine, vol.109, issue.5, pp.372-82, 1988.
DOI : 10.7326/0003-4819-109-5-372

E. Van-der-loo, J. Cnossen, and C. Meijer, Morphological aspects of T cell subpopulations in human blood: characterization of the cerebriform mononuclear cells in healthy individuals, Clin Exp Immunol, vol.43, issue.3, pp.506-522, 1981.

W. Morice, J. Katzmann, M. Pittelkow, R. Azhary, L. Gibson et al., Analysis, and TCR-PCR in Qualitative and Quantitative Assessment of Peripheral Blood Involvement by S??zary Syndrome, American Journal of Clinical Pathology, vol.125, issue.3, pp.364-74, 2006.
DOI : 10.1309/25E9Y7RRAY84HTAT

G. Brisou, D. Manzoni, S. Dalle, P. Felman, D. Morel et al., Alarms and Parameters Generated by Hematology Analyzer: New Tools to Predict and Quantify Circulating Sezary Cells, Journal of Clinical Laboratory Analysis, vol.106, issue.2, 2014.
DOI : 10.1002/jcla.21744

F. Heshmati, Mechanisms of action of extracorporeal photochemotherapy, Transfusion and Apheresis Science, vol.29, issue.1, pp.61-70, 2003.
DOI : 10.1016/S1473-0502(03)00103-4

R. Edelson, C. Berger, F. Gasparro, B. Jegasothy, P. Heald et al., Treatment of Cutaneous T-Cell Lymphoma by Extracorporeal Photochemotherapy, New England Journal of Medicine, vol.316, issue.6, pp.297-303, 1987.
DOI : 10.1056/NEJM198702053160603

R. Knobler, G. Berlin, P. Calzavara-pinton, H. Greinix, P. Jaksch et al., Guidelines on the use of extracorporeal photopheresis, Journal of the European Academy of Dermatology and Venereology, vol.36, issue.4, pp.1-37, 2014.
DOI : 10.1111/jdv.12311

X. Ronot and D. Grunwald, La cytométrie en flux: ostface de, Gérard Martet,... Editions Tec & Doc, 2006.

C. Surcouf, D. Delaune, T. Samson, and V. Foissaud, Analyse d'image en cytologie hématologique: automate CellaVision DM96 TM, Annales de Biologie Clinique, pp.419-443, 2009.

M. Girardi, J. Schechner, E. Glusac, C. Berger, and R. Edelson, Transimmunization and the evolution of extracorporeal photochemotherapy, Transfusion and Apheresis Science, vol.26, issue.3, 2002.
DOI : 10.1016/S1473-0502(02)00011-3

A. Marie-cardine, N. Viaud, N. Thonnart, R. Joly, S. Chanteux et al., IPH4102, a Humanized KIR3DL2 Antibody with Potent Activity against Cutaneous T-cell Lymphoma, Cancer Research, vol.74, issue.21, pp.6060-70, 2014.
DOI : 10.1158/0008-5472.CAN-14-1456

H. Sicard, C. Bonnafous, A. Morel, M. Bagot, A. Bensussan et al., A novel targeted immunotherapy for CTCL is on its way: Anti-KIR3DL2 mAb IPH4102 is potent and safe in non-clinical studies, OncoImmunology, vol.4, issue.9, p.1022306, 2015.
DOI : 10.1158/1078-0432.CCR-12-3488

L. Van-der-fits, M. Van-kester, Y. Qin, J. Out-luiting, F. Smit et al., MicroRNA-21 Expression in CD4+ T Cells Is Regulated by STAT3 and Is Pathologically Involved in S??zary Syndrome, Journal of Investigative Dermatology, vol.131, issue.3, 2011.
DOI : 10.1038/jid.2010.349