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Master Thesis

Usage des antibiotiques en médecine communautaire en Polynésie française : étude des consommations ambulatoires et enquête sur les pratiques auprès des médecins généralistes

Abstract : Objectives : the purpose is to study the community use of systemic antibiotics in French Polynesia. Methods : two descriptive studies have been carried out. One explores ambulatory consumption of antibiotics from pharmaceutical distributors’sales data in French Polynesia from 1999 to 2014 and in New Caledonia from 2005 to 2014. The other one evaluates GP’s pratices in Tahiti and Moorea, in nine routine medical practice diseases in a survey in 2014. Results : the global consumption is 40,3 DDD per 1000 inhabitants per day in 2014. Annual variations seems related to epidemics. Amoxicillin, Amoxicillin/clavulanate and Macrolids respectively represents 31,2%, 37,7% and 11,6% of consumptions. Level of consumptions in New Caledonia is comparable (p<0,01). A representative population of 58 GP’s participated. 42,9% of practices complied with guidelines. Noncompliant practices determinants related to physician represented 53,2% of determinants, the one related to social and epidemiological context respectively 19,5% and 17,5 %. Amoxicillin/clavulanate was frequently used in all clinical situations. Conclusion : the very high level of consumption seams to be explained by epidemiologic and social context, and by a large misuse, especially of Amoxicillin/clavulanate. Concret poposals to produce a practical guideline and to improve the use of antibiotics are done.
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Master Thesis
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https://dumas.ccsd.cnrs.fr/dumas-01306090
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Submitted on : Friday, April 22, 2016 - 12:16:22 PM
Last modification on : Wednesday, August 23, 2017 - 4:29:29 PM
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Camille Plaideau. Usage des antibiotiques en médecine communautaire en Polynésie française : étude des consommations ambulatoires et enquête sur les pratiques auprès des médecins généralistes. Médecine humaine et pathologie. 2016. ⟨dumas-01306090⟩

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