S. Palumbi, Humans as the World's Greatest Evolutionary Force, Science. 1 sept, vol.293, pp.1786-90, 2001.

D. Livermore, M. Blaser, O. Carrs, G. Cassell, N. Fishman et al., Discovery research: the scientific challenge of finding new antibiotics):1941?4. 3. World Health Organization. Antimicrobial resistance: global report on surveillance 2014, Disponible sur, 2011.

J. Taylor, M. Hafner, E. Yerushalmi, R. Smith, J. Bellasio et al., Estimating the economic costs of antimicrobial resistance Disponible sur: http://www.rand.org/pubs/research_reports/RR911.html 5. KPMG LLP. The global economic impact of anti-microbial resistance [en ligne]. 2014 [cité 1 mars 2015]. Disponible sur: https://www.kpmg.comIssue s%20and%20Insights/amr-report-final.pdf 6. The Review on Antimicrobial Resistance. Antimicrobial Resistance: Tackling a crisis for the health and wealth of nations, Disponible sur, p.2014, 2016.

. Ansm-agence-nationale-de-la-sécurité-du-médicament, L'évolution des consommations d'antibiotiques en France entre, 2000.

C. Datta, N. Faiers, M. Reeves, D. Brumfitt, W. Orskov et al., R FACTORS IN ESCHERICHIA COLI IN F??CES AFTER ORAL CHEMOTHERAPY IN GENERAL PRACTICE, The Lancet, vol.297, issue.7694, p.13
DOI : 10.1016/S0140-6736(71)91042-7

S. Levy and B. Marshall, Antibacterial resistance worldwide: causes, challenges and responses, Nature Medicine, vol.43, issue.12s, pp.312-317, 1971.
DOI : 10.1128/AAC.48.4.1295-1299.2004

A. Agence-nationale-de-la-sécurité-du-médicament, Mis à jour en novembre 2014 Disponible sur http://ansm.sante.fr/var/ansm_site/storage/original/application, InVS) et Agence nationale de sécurité du médicament et des produits de santé (ANSM). Consommation d'antibiotiques et résistance aux antibiotiques en France, pp.17-2015, 2000.

H. Chardon, Y. Péan, J. Delarbre, Y. Costa, and S. Maugat, Réseau européen de surveillance de la résistance bactérienne aux antibiotiques (EARS-Net) : résultats 2001-2010 pour la France et place en Europe European centre for disease prevention and control. Antimicrobial resistance surveillance in Europe, Bull Epidémiologique Hebd. nov, vol.20, pp.42-43, 2012.

R. Disponible-sur-http-hopstaken, C. Butler, J. Muris, J. Knottnerus, A. Kester et al., Do clinical findings in lower respiratory tract infection help general practitioners prescribe antibiotics appropriately? An observational cohort study in general practice, Family Practice, vol.23, issue.2, pp.180-187, 2006.
DOI : 10.1093/fampra/cmi100

N. Cassir, D. Marco, J. Poujol, A. Lagier, J. Denes et al., Prescriptions inappropriées d'antibiotiques chez l'enfant en médecine de ville : raisons et conséquences Antibiotic prescription by general practitioners for urinary tract infections in outpatients, Arch Pédiatrie. juin Eur J Clin Microbiol Infect Dis Off Publ Eur Soc Clin Microbiol. nov, vol.1931, issue.2311, pp.3079-83, 2012.

. France, Disponible sur: https://www.conseilnational .medecin.fr/sites, pdf 26. Goossens H, Ferech M, Vander Stichele R, Elseviers M. Outpatient antibiotic use, p.2015, 2015.

G. Bolokhovets, L. Ghazaryan, V. Abilova, G. Pyshnik, and T. Spasojevic, European centre for disease prevention and control. Surveillance of antimicrobial consumption in Europe 2012 Stockholm: ECDC; 2014. [en ligne] Disponible sur: http://ecdc.europa.eu/en/publications/Publications/antimicrobial-consumption-europe-esac- net-2012 Antibiotic use in eastern Europe: a cross-national database study in coordination with the WHO Regional Office for Europe, Antibiotic use in adult outpatients in Switzerland in relation to regions381?7. 32. Suda KJ TH. Trends and Seasonal Variation in Outpatient Antibiotic Prescription Rates in the United States, 2006.

J. Hutchinson, S. Jelinski, D. Hefferton, G. Desaulniers, and P. Parfrey, Role of diagnostic labeling in antibiotic prescription, Can Fam Physician Médecin Fam Can. juin, vol.47, pp.1217-1241, 2001.

C. Etienne and C. Pulcini, ??valuation prospective des prescriptions antibiotiques d???un ??chantillon de m??decins g??n??ralistes fran??ais, La Presse M??dicale, vol.44, issue.3, pp.59-66, 2015.
DOI : 10.1016/j.lpm.2014.07.022

C. Pulcini, L. Pauvif, A. Paraponaris, P. Verger, B. Ventelou et al., Perceptions and attitudes of French general practitioners towards rapid antigen diagnostic tests in acute pharyngitis using a randomized case vignette study Factors associated with the use of rapid antigen diagnostic tests in children presenting with acute pharyngitis among French general practitioners, J Antimicrob Chemother. juin Eur J Clin Microbiol Infect Dis, vol.6733, issue.405, pp.723-731, 2012.

G. Worrall, J. Hutchinson, G. Sherman, and J. Griffiths, Diagnosing streptococcal sore throat in adults: randomized controlled trial of in-office aids. Can Fam Physician Médecin Fam Can, avr, vol.53, issue.4, pp.666-71, 2007.

M. Cotter and L. Daly, Antibiotic prescription practices of general practitioners, Ir Med J

C. Pulcini, A. Naqvi, F. Gardella, P. Dellamonica, and A. Sotto, R??sistance bact??rienne et prescription antibiotique??: perceptions, attitudes et connaissances d???un ??chantillon de m??decins g??n??ralistes, M??decine et Maladies Infectieuses, vol.40, issue.12, pp.703-712, 2010.
DOI : 10.1016/j.medmal.2010.09.018

M. Murphy, C. Bradley, and S. Byrne, Antibiotic prescribing in primary care, adherence to guidelines and unnecessary prescribing - an Irish perspective, BMC Family Practice, vol.337, issue.1, p.43, 2012.
DOI : 10.1136/bmj.a1938

C. Llor, G. Rabanaque, A. López, and J. Cots, The adherence of GPs to guidelines for the diagnosis and treatment of lower urinary tract infections in women is poor, Family Practice, vol.28, issue.3, pp.294-303, 2011.
DOI : 10.1093/fampra/cmq107

L. Jørgensen, F. Christensen, S. , C. Currea, G. Llor et al., Antibiotic prescribing in patients with acute rhinosinusitis is not in agreement with European recommendations Adherence to guidelines on antibiotic treatment for respiratory tract infections in various categories of physicians: a retrospective cross-sectional study of data from electronic patient records Disponible sur, ):101?5. 47. Tell D, p.48, 2013.

I. Björkman, M. Erntell, M. Röing, C. Lundborg, F. Roque et al., Infectious disease management in primary care: perceptions of GPs Understanding physician antibiotic prescribing behaviour: a systematic review of qualitative studies, 203?12. 51. Vazquez-Lago JM, 2011.

F. Hyde, C. Phillips, L. Brookes-howell, K. Hood, T. Verheij et al., Are GPs' antibiotic prescribing patterns contextually dependent? A qualitative focus group study Primary care clinicians' perceptions of antibiotic resistance: a multi-country qualitative interview study General practitioners' perceptions of antimicrobial resistance: a qualitative study, 237?43. 54. Simpson SA, pp.158-65, 2007.

C. Pulcini, F. Williams, N. Molinari, P. Davey, D. Nathwani et al., Junior doctors' knowledge and perceptions of antibiotic resistance and prescribing: a survey in France and Scotland Knowledge, attitudes, and beliefs of French medical students about antibiotic prescribing and resistance, 80?7. 56. Dyar OJ, pp.423-453, 2011.

J. Søndergaard, K. Vach, J. Kragstrup, and M. Andersen, Impact of pharmaceutical representative visits on GPs' drug preferences, Family Practice, vol.26, issue.3, pp.204-213, 2009.
DOI : 10.1093/fampra/cmp010

S. Wang, C. Pulcini, C. Rabaud, J. Boivin, and J. Birgé, Inventory of antibiotic stewardship programs in general practice in France and abroad, 111?23. 59. World Health Organization (WHO). Critically Important Antimicrobials for Human, 2015.
DOI : 10.1016/j.medmal.2015.01.011

URL : https://hal.archives-ouvertes.fr/hal-01491697

A. Businger, L. Whaley, J. Gagne, and J. Linder, Disponible sur: http://apps.who.int/iris/bitstream Primary care clinicians' perceptions about antibiotic prescribing for acute bronchitis: a qualitative study, Medicine-3rd revision, p.194, 2011.

S. Kumar, P. Little, N. Britten, N. Scheppers, R. Hopstaken et al., Why do general practitioners prescribe antibiotics for sore throat? Grounded theory interview study, BMJ, vol.326, issue.7381, 2003.
DOI : 10.1136/bmj.326.7381.138

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC140007