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Master Thesis

Gliomes infiltrants et mémoire de travail : évaluation avant et après chirurgie éveillée, liens anatomo-fonctionnels

Abstract : Complaints about working memory impairments have been described by patients who received an awake brain surgery for a low-grade glioma. The purpose of this study is to assess the specific components of the working memory for this population, and to compare anatomical impairments with functional impairments of the working memory. First, we conducted a working memory assessment (referring to Baddeley’s cognitive model) for 8 patients at the pre-operative stage. Results were compared to 28 control subjects. We also assessed working memory for 4 of these patients, after surgery, and on 10 other patients, in order to evaluate the change in their performance, and the impact of the period between the assessment and the resection in working memory processes. In a second phase, we analyzed the link between anatomical impairments of the network underpinning the processes of the phonological loop, and functional impairments. Results showed a fragility of working memory, with heterogeneous patient profiles for their performances and the affected components. Matching between anatomical and functional impairments is not systematic.
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https://dumas.ccsd.cnrs.fr/dumas-01357229
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Submitted on : Monday, August 29, 2016 - 2:42:36 PM
Last modification on : Thursday, March 14, 2019 - 9:06:06 PM
Long-term archiving on: : Wednesday, November 30, 2016 - 1:37:29 PM

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  • HAL Id : dumas-01357229, version 1

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Sophie Bouteloup, Alice Lebret. Gliomes infiltrants et mémoire de travail : évaluation avant et après chirurgie éveillée, liens anatomo-fonctionnels. Sciences cognitives. 2016. ⟨dumas-01357229⟩

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