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une pathologie maligne. L'objectif principal de ce travail était l'évaluation d'un nouveau protocole d'antibiothérapie, par Tazocilline®, dans le traitement des neutropénies fébriles en oncologie pédiatrique dans le service de pédiatrie du centre hospitalier universitaire (CHU) de Brest Etude de comparaison historique, réalisée dans le service de pédiatrie du CHU de Brest. Comparaison d'un nouveau protocole à l'ancien appliqué dans le service afin d'évaluer son efficacité et sa tolérance, Pas de différence de succès ou d'échec du nouveau protocole en comparaison à l'ancien et pas de différence sur le plan des complications. L'utilisation de la Tazocilline® en monothérapie dans le traitement de la neutropénie fébrile en oncologie pédiatrique semble possible mais il n'existe encore que peu de connaissances à son sujet chez l'enfant ,