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Master Thesis

Évaluation médico-économique du programme d’éducation thérapeutique de l’étude ETHAP (étude de soins courants, contrôlée, randomisée, multicentrique) sur l’hypertension artérielle pulmonaire

Abstract : To reduce adverse drug reactions (ADR) in pulmonary hypertension, a pharmacist collaborative care (CC) program was set up in Grenoble and evaluated by the ETHAP study. The present work is aimed at estimating the cost (based on the ETHAP data) and consequences in monetary unit of the program, compared to usual care (UC). Consequences are reduced to unsolved DRP as this parameter was statistically significant between the two groups in the ETHAP study. Hospitalizations related to unsolved DRP were measured using two different methods: bibliographic (bibliographic hospitalization risk) and experimental (hospitalization related to unsolved DRP that occurred during the ETHAP study). Design and setting up of the program have been evaluated at 74 486€ for 10 centers, and operating cost at 10 192€ for 37.6 patient.year so 271€ per patient. Using the bibliographic approach, unsolved DRP are responsible for 13 092€ hospitalization costs in the UC group and 4270€ in the CC group. Using the experimental approach, the costs are respectively 50 659€ and 10 in the UC and CC group. The use of two complementary approaches allowed us to calculate a range (bibliographic; experimental) in which the real net benefit of the program might be (taking into account only the operating costs): between -36.4 €/patient and 30 441€ for 37.6 patient.year (809.7 €/patient). Taking also into account design and setting up costs, 92 patient.year have to follow the program in the 10 centers to have a positive net benefit (experimental results).
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Master Thesis
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https://dumas.ccsd.cnrs.fr/dumas-01387907
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Submitted on : Wednesday, October 26, 2016 - 11:25:45 AM
Last modification on : Wednesday, July 15, 2020 - 8:56:03 AM

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  • HAL Id : dumas-01387907, version 1

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Marie Coste. Évaluation médico-économique du programme d’éducation thérapeutique de l’étude ETHAP (étude de soins courants, contrôlée, randomisée, multicentrique) sur l’hypertension artérielle pulmonaire. Sciences pharmaceutiques. 2015. ⟨dumas-01387907⟩

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