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Master Thesis

Les bienfaits du vin rouge sur la santé et l’avenir du resvératrol en tant que médicament

Abstract : The wine is the alcoholic drink the most consumed in France in spite of a clear decrease of the rate of regular consumers because it ‘s the occasional mode (1 - 2 times a week or more rarely) that prevails. Our survey that was conducted on 76 patients (45-88 years) in the department of cardiac care in the CHU (teaching hospital) of Grenoble indicates that 34,2 % of regular consumers of red wine who are older than those consuming other alcohols ; women consume fewer alcoholic drinks than the men ; regular consumer patients of the other alcohols take statines with a higher dose in comparison to regular consumers of red wine. The polyphenols of the red wine would have multiple beneficial properties: this association is at the origin of "French Paradox" : the cardiovascular mortality of the French people is lower than of the other countries with identical consumption of fats. This phenomenon would be due to the Mediterranean diet and/or the consumption of red wine in moderate quantity, thanks to its content in resvératrol (studied polyphenol). Most of the studies which illustrate all its properties, were led in vitro or tested on animals, where makes it hard to convert to a human scale. Clinical trials and meta analysis must be led before considering this molecule as a medicine. At present, the resvératrol is currently on the market in the form of food complements even if it has no current claim.
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Master Thesis
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https://dumas.ccsd.cnrs.fr/dumas-01417875
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Submitted on : Friday, December 16, 2016 - 10:25:54 AM
Last modification on : Wednesday, July 15, 2020 - 8:56:03 AM
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  • HAL Id : dumas-01417875, version 1

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Marina Vauche. Les bienfaits du vin rouge sur la santé et l’avenir du resvératrol en tant que médicament. Sciences pharmaceutiques. 2016. ⟨dumas-01417875⟩

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