L. Entreprises and . Médicament, 100 questions que l'on nous pose, 2012.

S. Stremersch and A. Lemmens, Sales Growth of New Pharmaceuticals Across the Globe: The Role of Regulatory Regimes, Marketing Science, vol.28, issue.4, pp.690-708, 2009.
DOI : 10.1287/mksc.1080.0440

D. Kvesic, Product lifecycle management: marketing strategies for the pharmaceutical industry, Journal of Medical Marketing, vol.330, issue.4, pp.293-301, 2008.
DOI : 10.1057/jmm.2008.23

J. K. Christiansen, C. J. Varnes, M. Gasparin, D. Storm-nielsen, and E. Vinther, Living Twice: How a Product Goes through Multiple Life Cycles*, Journal of Product Innovation Management, vol.43, issue.(4, pp.797-827, 2010.
DOI : 10.1111/j.1540-5885.2010.00753.x

URL : https://lra.le.ac.uk/bitstream/2381/32025/2/John%20-%20LIVING%20AT%20LEAST%20TWICE%20-%20v6_14-6-2010_John%20updated_Juli_2010.3.pdf

A. Joseph, &. Dimasi, B. Laura, and . Faden, Competitiveness in follow-on drug R&D: a race or imitation?, Nature Reviews Drug Discovery, vol.10, pp.23-27, 2011.

R. Dubey and J. Dubey, Pharmaceutical product differentiation: A strategy for strengthening product pipeline and life cycle management, Journal of Medical Marketing: Device, Diagnostic and Pharmaceutical Marketing, pp.104-118, 2009.

D. Kvesic, Adalat?A Lifecycle Managed Journal of Medical Marketing: Device, Diagnostic and Pharmaceutical Marketing, pp.187-200, 2009.

S. Paul, D. Mytelka, C. Dunwiddie, C. Persinger, B. Munos et al., How to improve R&D productivity: the pharmaceutical industry's grand challenge, Nature Reviews Drug Discovery, vol.116, issue.3, pp.201-215, 2010.
DOI : 10.1038/nrd3078

F. Pammolli, L. Magazzini, and M. Riccaboni, The productivity crisis in pharmaceutical R&D, Nature Reviews Drug Discovery, vol.23, issue.6, pp.428-466, 2011.
DOI : 10.1038/nrd3405

R. Dewar and J. Dutton, The Adoption of Radical and Incremental Innovations: An Empirical Analysis, Management Science, vol.32, issue.11, pp.1422-1455, 1986.
DOI : 10.1287/mnsc.32.11.1422

C. P. Adams, V. Van, and . Brantner, Estimating the cost of new drug development: is it really $802 Million? Health Affairs, pp.420-448, 2006.

J. A. Dimasia and H. G. Grabowskib, The cost of biopharmaceutical R&D: is biotech different?, Managerial and Decision Economics, vol.13, issue.4-5, pp.469-79, 2007.
DOI : 10.1002/mde.1360

M. Steiner, D. Bugen, W. Kazanchy, I. Knox, V. Margaret et al., The Continuing Evolution of the Pharmaceutical Industry: Career Challenges and Opportunities, 2012.

A. Salviati, A. P. Burlina, and W. Borsini, Nervous system and Fabry disease, from symptoms to diagnosis: damage evaluation and follow-up in adult patients, enzyme replacement, and support therapy, Neurological Sciences, vol.30, issue.Suppl 451, pp.299-306, 2010.
DOI : 10.1007/s10072-009-0211-y

H. Morse, Product market definition in the pharmaceutical industry, Antitrust Law Journal, issue.271, pp.633-76, 2003.

J. Mark and . Belsey, Drug developer strategies to boost competitiveness, Nature Reviews: Drug Discovery, vol.6, pp.265-66, 2007.

J. Beney and V. Von-gunten, Les Biosimilaires ne sont pas des génériques. Caduceus express, 2009.

A. Joseph, &. Dimasi, B. Laura, and . Faden, Competitiveness in follow-on drug R&D: a race or imitation?, Nature Reviews Drug Discovery, vol.10, pp.23-27, 2011.

P. M. Danzon, A. Epstein, and S. Nicholson, Mergers and acquisitions in the pharmaceutical and biotech industries, Managerial and Decision Economics, vol.33, issue.4-5, pp.307-328, 2007.
DOI : 10.1002/mde.1343

V. Dickov and B. Kuzman, Specific features of pharmaceuticals marketing mix Journal of Management & Marketing in Healthcare, pp.160-167, 2011.

F. Alkhateeb, N. Khanfar, W. Doucette, and D. Loudon, Characteristics of Physicians Targeted by the Pharmaceutical Industry to Participate in E-detailing, Health Marketing Quarterly, vol.155, issue.2, pp.98-116, 2009.
DOI : 10.1377/hlthaff.5.3.91

A. Matthew, Changing channels Medical Marketing & Media, pp.34-42, 2005.

P. Norris, A. Herxheimer, J. Lexchin, and P. Mansfield, Drug promotion: what we know, what we have yet to learn. Reviews of materials in the WHO

P. Henning and A. Schnur, eLearning in continuing medical education: A comparison of knowledge gain and learning efficiency, Journal of Medical Marketing, vol.9, issue.2, pp.156-161, 2009.
DOI : 10.1057/jmm.2009.5

M. Joshi, T. Jambulingam, and R. Kathuria, Benchmarking web based CRM strategies of pharmaceutical companies : a competitive analysis using analytic hierarchy process. Health Care and Pharmaceutical Management, pp.417-422

W. Lundstrom and R. Wright, The CRM?physician interface: Toward a model of physician relationship building Journal of Medical Marketing: Device, Diagnostic and Pharmaceutical Marketing, pp.316-323, 2005.

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