E. Abraham and E. Chain, An Enzyme from Bacteria able to Destroy Penicillin, Nature, vol.146, issue.3713, pp.677-685, 1940.
DOI : 10.1038/146837a0

S. Palumbi, Humans as the world's greatest evolutionary force, Science. Sep, vol.7293, issue.5536, pp.1786-90, 2001.

N. Datta and P. Kontomichalou, Penicillinase Synthesis Controlled By Infectious R Factors In Enterobacteriaceae, Nature, vol.87, issue.5007, pp.239-280, 1965.
DOI : 10.1021/ac60172a054

J. Lederberg and . Plasmid, Plasmid (1952???1997), Plasmid, vol.39, issue.1, pp.1-9, 1952.
DOI : 10.1006/plas.1997.1320

R. Ambler, The Structure of <latex>$\beta$</latex>-Lactamases, Philosophical Transactions of the Royal Society B: Biological Sciences, vol.289, issue.1036, pp.321-352, 1036.
DOI : 10.1098/rstb.1980.0049

K. Bush and G. Jacoby, Updated Functional Classification of ??-Lactamases, Antimicrobial Agents and Chemotherapy, vol.54, issue.3, pp.969-76, 2010.
DOI : 10.1128/AAC.01009-09

H. Knothe, P. Shah, V. Krcmery, M. Antal, and S. Mitsuhashi, Ubertragbare Resistenz gegen??ber Cefotaxim, Cefoxitin, Cefamandol und Cefuroxim in klinischen Isolaten von Klebsiella pneumoniae und Serratia marcescens, Infection, vol.147, issue.6, pp.315-322, 1983.
DOI : 10.1007/BF01641355

W. Zhao and Z. Hu, Epidemiology and genetics of CTX-M extended-spectrum ?lactamases in Gram-negative bacteria. Critical reviews in microbiology, 2012.

C. Giske, A. Sundsfjord, G. Kahlmeter, N. Woodford, P. Nordmann et al., Redefining extended-spectrum beta-lactamases: balancing science and clinical need, J
DOI : 10.1093/jac/dkn444

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721700

J. Lyon and . Imipenem, cilastatin: the first carbapenem antibiotic, Drug Intell Clin Pharm, vol.19, issue.12, pp.895-904, 1985.

C. Lee, G. Lui, M. Ip, T. Ling, and N. Lee, Frequent detection of plasmid-mediated quinolone resistance (qnr) genes in multidrug-resistant Enterobacteriaceae blood isolates, Hong Kong. European journal of clinical microbiology & infectious diseases: official publication of the European Society of Clinical Microbiology, 2012.

C. Schultsz and S. Geerlings, Plasmid-Mediated Resistance in Enterobacteriaceae, Drugs, vol.11, issue.11, pp.1-16, 2012.
DOI : 10.2165/11597960-000000000-00000

A. Buré, P. Legrand, G. Arlet, V. Jarlier, G. Paul et al., Dissemination in five French hospitals of Klebsiella pneumoniae serotype K25 harbouring a new transferable enzymatic resistance to third generation cephalosporins and aztreonam. Eur, J. Clin

A. Medeiros, Nosocomial Outbreaks of Multiresistant Bacteria: Extended-Spectrum Beta-Lactamases Have Arrived in North America, Annals of Internal Medicine, vol.119, issue.5, pp.428-458, 1993.
DOI : 10.7326/0003-4819-119-5-199309010-00015

K. Meyer, C. Urban, J. Eagan, B. Berger, and J. Rahal, Nosocomial Outbreak of Klebsiella Infection Resistant to Late-Generation Cephalosporins, Annals of Internal Medicine, vol.119, issue.5, pp.353-361, 1993.
DOI : 10.7326/0003-4819-119-5-199309010-00001

T. Coque, F. Baquero, and R. Canton, Increasing prevalence of ESBL-producing Enterobacteriaceae in Europe Available from, Euro Surveill, vol.13, issue.47, 2008.

R. Cantón and T. Coque, The CTX-M ??-lactamase pandemic, Current Opinion in Microbiology, vol.9, issue.5, pp.466-75, 2006.
DOI : 10.1016/j.mib.2006.08.011

E. Reuland, I. Overdevest, A. Naiemi, N. Kalpoe, J. Rijnsburger et al., High prevalence of ESBL-producing Enterobacteriaceae carriage in Dutch community patients with gastrointestinal complaints. Clinical microbiology and infection: the official publication of the European Society of Clinical Microbiology and Infectious Diseases [Internet], 2012.

O. Kizilca, R. Siraneci, A. Yilmaz, N. Hatipoglu, E. Ozturk et al., Risk Factors for Community-Aquired Urinary Tract Infection with ESBL-Producing Bacteria in Children, Pediatr Int [Internet], p.22882781, 2012.

R. Horton, L. Randall, E. Snary, H. Cockrem, S. Lotz et al., Fecal Carriage and Shedding Density of CTX-M Extended-Spectrum ??-Lactamase-Producing Escherichia coli in Cattle, Chickens, and Pigs: Implications for Environmental Contamination and Food Production, Applied and Environmental Microbiology, vol.77, issue.11, pp.3715-3724, 2011.
DOI : 10.1128/AEM.02831-10

E. Meyer, P. Gastmeier, A. Kola, and F. Schwab, Pet animals and foreign travel are risk factors for colonisation with extended-spectrum ??-lactamase-producing Escherichia coli, Infection, vol.350, issue.6, 2012.
DOI : 10.1007/s15010-012-0324-8

D. Girlich, L. Poirel, and P. Nordmann, Diversity of clavulanic acid-inhibited extendedspectrum ?-lactamases in Aeromonas spp. from the Seine River

J. Carlet, V. Jarlier, S. Harbarth, A. Voss, H. Goossens et al., Ready for a world without antibiotics? The Pensi??res Antibiotic Resistance Call to Action, Antimicrobial Resistance and Infection Control, vol.1, issue.1, p.11, 2012.
DOI : 10.3201/eid1707.110209

F. Barbier and M. Wolff, [Multi-drug resistant Pseudomonas aeruginosa: towards a therapeutic dead end?, Med Sci, vol.26, issue.11, pp.960-968, 2010.

J. Carlet and J. Mainardi, Antibacterial agents: back to the future? Can we live with only colistin, co-trimoxazole and fosfomycin?, Clinical Microbiology and Infection, vol.18, issue.1, pp.1-3, 2012.
DOI : 10.1111/j.1469-0691.2011.03702.x

J. Carlet, C. Rambaud, and C. Pulcini, WAAR (World Alliance against Antibiotic Resistance): Safeguarding antibiotics, Med Mal Infect, 2012.
DOI : 10.1016/j.medmal.2012.07.001

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570339

L. Ministère-de and . Santé, Plan National Alerte sur les Antibiotiques, 2011.

R. Mishra, E. Oviedo-orta, P. Prachi, R. Rappuoli, and F. Bagnoli, Vaccines and antibiotic resistance, Current Opinion in Microbiology, vol.15, issue.5, 2012.
DOI : 10.1016/j.mib.2012.08.002

D. Roux, G. Pier, and D. Skurnik, Magic bullets for the 21st century: the reemergence of immunotherapy for multi- and pan-resistant microbes, Journal of Antimicrobial Chemotherapy, vol.67, issue.12, 2012.
DOI : 10.1093/jac/dks335

W. Lo, P. Ho, K. Chow, E. Lai, F. Yeung et al., Fecal carriage of CTXM type extended-spectrum beta-lactamase-producing organisms by children and their household contacts, Journal of Infection, vol.60, issue.4, pp.286-92, 2010.
DOI : 10.1016/j.jinf.2010.02.002

M. Macrae, K. Shannon, D. Rayner, A. Kaiser, P. Hoffman et al., A simultaneous outbreak on a neonatal unit of two strains of multiply antibiotic resistant Klebsiella pneumoniae controllable only by ward closure, Journal of Hospital Infection, vol.49, issue.3, 2001.
DOI : 10.1053/jhin.2001.1066

J. Rebuck, K. Olsen, P. Fey, A. Langnas, and M. Rupp, Characterization of an outbreak due to extended-spectrum beta-lactamase-producing Klebsiella pneumoniae in a pediatric intensive care unit transplant population, Clin. Infect. Dis, 2000.

L. Chandramohan and P. Revell, Prevalence and molecular characterization of extendedspectrum ?-lactamase producing Enterobacteriaceae in a pediatric patient population

C. De, D. Prioux, and E. , Infections invasives à bactéries productrices de _lactamases à spectre étendu chez l'enfant Etude rétrospective dans un Centre Hospitalier

W. Al-herz, A. Bousfiha, J. Casanova, H. Chapel, M. Conley et al., Primary immunodeficiency diseases: an update on the classification from the international union of immunological societies expert committee for primary immunodeficiency, Front Immunol, vol.2, p.54, 2011.

W. Al-herz and M. Moussa, Survival and Predictors of Death Among Primary Immunodeficient Patients: A Registry-Based Study, Journal of Clinical Immunology, vol.20, issue.5, pp.467-73, 2012.
DOI : 10.1007/s10875-011-9636-1

T. Ed, L. Hl-jr, L. Wc, and F. Jw, Intravenous infusion of bone marrow in patients receiving radiation and chemotherapy, N. Engl. J. Med, vol.257, issue.11, pp.491-497, 1957.

M. G. Hartmann-l, L. A. , and B. J. , Attempt at protection against radiogold-induced mortality by injection of isologous or homologous bone marrow cells], Rev Fr Etud Clin Biol, vol.3, issue.10, pp.1086-1093, 1958.

R. Gatti, H. Meuwissen, H. Allen, R. Hong, and R. Good, Immunological reconstitution of sex-linked lymphopenic immunological deficiency. Lancet, pp.1366-1375, 1968.

F. Bach, R. Albertini, P. Joo, J. Anderson, and M. Bortin, Bone-marrow transplantation in a patient with the Wiskott-Aldrich syndrome. Lancet, pp.1364-1370, 1968.

F. Appelbaum, Hematopoietic-Cell Transplantation at 50, New England Journal of Medicine, vol.357, issue.15, pp.1472-1477, 2007.
DOI : 10.1056/NEJMp078166

A. Freifeld, E. Bow, K. Sepkowitz, M. Boeckh, J. Ito et al., Clinical Practice Guideline for the Use of Antimicrobial Agents in Neutropenic Patients with Cancer: 2010 Update by the Infectious Diseases Society of America, Clinical Infectious Diseases, vol.52, issue.4, pp.56-93, 2011.
DOI : 10.1093/cid/cir073

S. Demir, A. Soysal, M. Bakir, M. Kaufmann, and A. Yagci, in paediatric wards: A nested case-control study, Journal of Paediatrics and Child Health, vol.40, issue.10, pp.548-53, 2008.
DOI : 10.1111/j.1440-1754.2008.01326.x

Y. Kim, H. Pai, H. Lee, S. Park, E. Choi et al., Bloodstream Infections by Extended-Spectrum ??-Lactamase-Producing Escherichia coli and Klebsiella pneumoniae in Children: Epidemiology and Clinical Outcome, Antimicrobial Agents and Chemotherapy, vol.46, issue.5, pp.1481-91, 2002.
DOI : 10.1128/AAC.46.5.1481-1491.2002

M. Arnan, C. Gudiol, L. Calatayud, J. Liñares, M. Dominguez et al., Risk factors for, and clinical relevance of, faecal extended-spectrum ??-lactamase producing Escherichia coli (ESBL-EC) carriage in neutropenic patients with haematological malignancies, European Journal of Clinical Microbiology & Infectious Diseases, vol.18, issue.3, pp.355-60, 2011.
DOI : 10.1007/s10096-010-1093-x

M. Abbassi, C. Torres, W. Achour, L. Vinué, Y. Sáenz et al., Genetic characterisation of CTX-M-15-producing Klebsiella pneumoniae and Escherichia coli strains isolated from stem cell transplant patients in Tunisia, International Journal of Antimicrobial Agents, vol.32, issue.4, pp.308-322, 2008.
DOI : 10.1016/j.ijantimicag.2008.04.009

L. Vidal-navarro, C. Pfeiffer, N. Bouziges, A. Sotto, and J. Lavigne, Faecal carriage of multidrug-resistant Gram-negative bacilli during a non-outbreak situation in a French university hospital, Journal of Antimicrobial Chemotherapy, vol.65, issue.11, pp.2455-2463, 2010.
DOI : 10.1093/jac/dkq333

A. Kola, M. Holst, I. Chaberny, S. Ziesing, S. Suerbaum et al., Surveillance of extended-spectrum ??-lactamase-producing bacteria and routine use of contact isolation: experience from a three-year period, Journal of Hospital Infection, vol.66, issue.1, pp.46-51, 2007.
DOI : 10.1016/j.jhin.2007.01.006

J. Tham, M. Walder, E. Melander, and I. Odenholt, Duration of colonization with extendedspectrum beta-lactamase-producing Escherichia coli in patients with travellers' diarrhoea. Scand, J. Infect. Dis, vol.44, issue.8, pp.573-580, 2012.

D. Sleijfer, N. Mulder, H. De-vries-hospers, V. Fidler, H. Nieweg et al., Infection prevention in granulocytopenic patients by selective decontamination of the digestive tract, European Journal of Cancer (1965), vol.16, issue.6, pp.859-69, 1980.
DOI : 10.1016/0014-2964(80)90140-1

A. Liberati, D. Amico, R. Pifferi, S. Telaro, and E. , Antibiotic prophylaxis in intensive care units: meta-analyses versus clinical practice, Intensive Care Medicine, vol.26, issue.0, pp.38-44, 2000.
DOI : 10.1007/s001340051117

A. Naiemi, N. Heddema, E. Bart, A. De-jonge, E. Vandenbroucke-grauls et al., Emergence of multidrug-resistant Gram-negative bacteria during selective decontamination of the digestive tract on an intensive care unit--authors' response, Journal of Antimicrobial Chemotherapy, vol.60, issue.2, pp.853-859, 2006.
DOI : 10.1093/jac/dkm189

M. Bonten and H. Grundmann, Selective digestive decontamination and antibiotic resistance: A balancing act *, Critical Care Medicine, vol.31, issue.8, pp.2239-2279, 2003.
DOI : 10.1097/01.CCM.0000080491.46005.3F

G. Zobel, M. Kuttnig, H. Grubbauer, H. Semmelrock, and W. Thiel, Reduction of colonization and infection rate during pediatric intensive care by selective decontamination of the digestive tract, Critical Care Medicine, vol.19, issue.10, pp.1242-1248, 1991.
DOI : 10.1097/00003246-199110000-00005

J. Barret, M. Jeschke, and D. Herndon, Selective decontamination of the digestive tract in severely burned pediatric patients, Burns, vol.27, issue.5, pp.439-484, 2001.
DOI : 10.1016/S0305-4179(00)00147-9

F. Ruza, F. Alvarado, R. Herruzo, M. Delgado, S. García et al., Prevention of nosocomial infection in a pediatric intensive care unit (PICU) through the use of selective digestive decontamination, European Journal of Epidemiology, vol.14, issue.7, pp.719-746, 1998.
DOI : 10.1023/A:1007487330893

S. Smith, R. Jackson, C. Hannakan, R. Wadowsky, A. Tzakis et al., Selective decontamination in pediatric liver transplants. A randomized prospective study, Transplantation, vol.55, issue.6, pp.1306-1315, 1993.

F. Leclerc and O. Noizet, Does selective digestive decontamination prevent nosocomial infections?]. Arch Pediatr, Feb, vol.11, issue.2, pp.175-184, 2004.

H. Guiot and R. Van-furth, SUMMARY, Epidemiology and Infection, vol.89, issue.03, pp.349-60, 1992.
DOI : 10.3109/00365548609032322

URL : https://hal.archives-ouvertes.fr/in2p3-00917773

L. Rhodes, H. Van-saene, S. White, S. Fairclough, L. Ball et al., Microbial carriage, sepsis, infection and acute GVHD in the first 25 BMT at the Royal Liverpool Children's Hospital, Bone Marrow Transplant, vol.11, issue.4, pp.261-270, 1993.

H. Mitsui, T. Karasuno, T. Santo, K. Fukushima, H. Matsunaga et al., Analysis of sepsis in allogeneic bone marrow transplant recipients: a single-center study, Journal of Infection and Chemotherapy, vol.9, issue.3
DOI : 10.1007/s10156-003-0252-8

J. Vossen, P. Heidt, H. Van-den-berg, E. Gerritsen, J. Hermans et al., Prevention of infection and graft-versus-host disease by suppression of intestinal microflora in children treated with allogeneic bone marrow transplantation, European Journal of Clinical Microbiology & Infectious Diseases, vol.108, issue.Supplement 1, pp.14-23, 1990.
DOI : 10.1007/BF01969527

M. Buehlmann, T. Bruderer, R. Frei, and A. Widmer, Effectiveness of a new decolonisation regimen for eradication of extended-spectrum ??-lactamase-producing Enterobacteriaceae, Journal of Hospital Infection, vol.77, issue.2
DOI : 10.1016/j.jhin.2010.09.022

F. Abecasis, R. Sarginson, S. Kerr, N. Taylor, and H. Van-saene, Is selective digestive decontamination useful in controlling aerobic gram-negative bacilli producing extended spectrum beta-lactamases? Microb. Drug Resist, pp.17-23, 2011.

E. Oostdijk, A. De-smet, J. Kesecioglu, and M. Bonten, Decontamination of cephalosporin-resistant Enterobacteriaceae during selective digestive tract decontamination in intensive care units, Journal of Antimicrobial Chemotherapy, vol.67, issue.9, p.2012
DOI : 10.1093/jac/dks187

T. Sarashina, M. Yoshida, A. Iguchi, H. Okubo, N. Toriumi et al., Risk Factor Analysis of Bloodstream Infection in Pediatric Patients After Hematopoietic Stem Cell Transplantation, Journal of Pediatric Hematology/Oncology, vol.35, issue.1, 2012.
DOI : 10.1097/MPH.0b013e3182677f35

D. Poutsiaka, L. Price, A. Ucuzian, G. Chan, K. Miller et al., Blood stream infection after hematopoietic stem cell transplantation is associated with increased mortality, Bone Marrow Transplantation, vol.9, issue.1, pp.63-70, 2007.
DOI : 10.1038/sj.bmt.1705690

M. Crocetti, N. Moghbeli, and J. Serwint, Fever Phobia Revisited: Have Parental Misconceptions About Fever Changed in 20 Years?, PEDIATRICS, vol.107, issue.6, pp.1241-1247, 2001.
DOI : 10.1542/peds.107.6.1241

A. Karwowska, C. Nijssen-jordan, D. Johnson, and H. Davies, Conclusions:, CJEM, vol.20, issue.06, 2002.
DOI : 10.1001/archpedi.1980.02130140050015

E. Purssell, Fever phobia revisited, Arch. Dis. Child, vol.89, issue.1, pp.89-90, 2004.

M. Enarson, S. Ali, B. Vandermeer, R. Wright, T. Klassen et al., Beliefs and Expectations of Canadian Parents Who Bring Febrile Children for Medical Care, PEDIATRICS, vol.130, issue.4, 2012.
DOI : 10.1542/peds.2011-2140

C. Gudiol, L. Calatayud, C. Garcia-vidal, J. Lora-tamayo, M. Cisnal et al., Bacteraemia due to extended-spectrum ??-lactamase-producing Escherichia coli (ESBL-EC) in cancer patients: clinical features, risk factors, molecular epidemiology and outcome, Journal of Antimicrobial Chemotherapy, vol.65, issue.2, pp.333-374, 2010.
DOI : 10.1093/jac/dkp411