Ein heizbarer Objecttisch und seine Verwendung bei Untersuchungen des Blutes. Arch Für Mikrosk Anat. 1 déc 1865, pp.1-42 ,
DOI : 10.1007/bf02961404
Ueber einen neuen Forrnbestandteil des Blutes und dessen Rolle bei der Thrombose und Blutgerinnung, Arch Für Pathol Anat Physiol Für Klin Med, vol.90, pp.261-332, 1882. ,
DOI : 10.1007/bf01931360
A Direct Measurement of the Radiation Sensitivity of Normal Mouse Bone Marrow Cells, Radiation Research, vol.14, issue.2, pp.3-7, 1961. ,
DOI : 10.2307/3570892
Hematopoietic Stem Cells, The American Journal of Pathology, vol.169, issue.2, pp.338-384, 2006. ,
DOI : 10.2353/ajpath.2006.060312
Hematopoietic stem cells: concepts, definitions, and the new reality, Blood, vol.125, issue.17, pp.2605-2618, 2015. ,
DOI : 10.1182/blood-2014-12-570200
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440889
Regulation of megakaryocyte maturation and platelet formation, Journal of Thrombosis and Haemostasis, vol.113, issue.Suppl. 1, pp.227-261, 2009. ,
DOI : 10.1111/j.1538-7836.2009.03398.x
Megakaryocyte endomitosis is a failure of late cytokinesis related to defects in the contractile ring and Rho/Rock signaling, Blood, vol.112, issue.8, pp.3164-3174, 2008. ,
DOI : 10.1182/blood-2008-03-144956
Dynamic Visualization of Thrombopoiesis Within Bone Marrow, Science, vol.108, issue.5, pp.1767-70, 2007. ,
DOI : 10.1182/blood-2005-11-011957
URL : http://mediatum.ub.tum.de/doc/675124/document.pdf
The molecular mechanisms that control thrombopoiesis, Journal of Clinical Investigation, vol.115, issue.12, pp.3339-3386, 2005. ,
DOI : 10.1172/JCI26674
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1297257
The reciprocal relationship of thrombopoietin (c-Mpl ligand) to changes in the platelet mass during busulfan-induced thrombocytopenia in the rabbit, Blood. 15 mai, vol.85, issue.10, pp.2720-2750, 1995. ,
Hemostasis and Thrombosis, Blood Coagulation & Fibrinolysis, vol.6, issue.2, 1903. ,
DOI : 10.1097/00001721-199504000-00015
The blood platelet open canalicular system: a two-way street, Eur J Cell Biol. déc, vol.56, issue.2, pp.233-275, 1991. ,
The fate of the open canalicular system in surface and suspension-activated platelets, Blood. 1 nov, vol.74, issue.6, pp.1983-1991, 1989. ,
The substructure of human platelet microtubules, Blood. oct, vol.32, issue.4, pp.638-686, 1968. ,
The Platelet: Form and Function, Seminars in Hematology, vol.43, pp.94-100, 2006. ,
DOI : 10.1053/j.seminhematol.2005.11.004
The actin cytoskeleton differentially regulates platelet ??-granule and dense-granule secretion, Blood, vol.105, issue.10, pp.3879-3887, 2005. ,
DOI : 10.1182/blood-2004-04-1392
A review of platelet secretion assays for the diagnosis of inherited platelet secretion disorders, Thrombosis and Haemostasis, vol.114, issue.1, pp.14-25, 2015. ,
DOI : 10.1160/TH14-11-0999
Platelet and Megakaryocyte Dense Granules Contain Glycoproteins Ib and IIb-IIIa, Blood. 1 juin, vol.89, issue.11, pp.4047-57, 1997. ,
The protein CD63 is in platelet dense granules, is deficient in a patient with Hermansky-Pudlak syndrome, and appears identical to granulophysin., Journal of Clinical Investigation, vol.91, issue.4, pp.1775-82, 1993. ,
DOI : 10.1172/JCI116388
The lysosomal granule membrane protein, LAMP-2, is also present in platelet dense granule membranes, Thromb Haemost. avr, vol.75, issue.4, pp.623-632, 1996. ,
Endothelium-derived relaxing and contracting factors, FASEB J Off Publ Fed Am Soc Exp Biol. juill, vol.3, issue.9, pp.2007-2025, 1989. ,
Arterial thrombosis???insidious, unpredictable and deadly, Nature Medicine, vol.17, issue.11, pp.1423-1459, 2011. ,
DOI : 10.1007/BF01931360
Platelet integrins and immunoreceptors, Immunological Reviews, vol.82, issue.1, pp.247-64, 2007. ,
DOI : 10.1074/jbc.R900037199
Activation of Platelet Function Through G Protein-Coupled Receptors, Circulation Research, vol.99, issue.12, pp.1293-304, 2006. ,
DOI : 10.1161/01.RES.0000251742.71301.16
Nouvelles molécules ciblées et modulation des fonctions plaquettaires : anticiper, démontrer, gérer, utiliser, Hématologie. 1 oct, vol.16, issue.5, pp.345-54, 2010. ,
The leucine-rich repeat: a versatile binding motif, Trends in Biochemical Sciences, vol.19, issue.10, pp.415-436, 1994. ,
DOI : 10.1016/0968-0004(94)90090-6
Glycoprotein Ib?? forms disulfide bonds with 2 glycoprotein Ib?? subunits in the resting platelet, Blood, vol.109, issue.2, p.603, 2007. ,
DOI : 10.1182/blood-2006-05-024091
Signalisation via le complexe GPIb-V-IX plaquettaire. Hématologie. 29 sept, pp.273-84, 2008. ,
Substructure of human von Willebrand factor., Journal of Clinical Investigation, vol.76, issue.4, pp.1491-500, 1985. ,
DOI : 10.1172/JCI112129
Shear-dependent changes in the three-dimensional structure of human von Willebrand factor, Blood. 15 oct, vol.88, issue.8, pp.2939-50, 1996. ,
Thrombospondin-1 mediates platelet adhesion at high shear via glycoprotein Ib (GPIb): an alternative/backup mechanism to von Willebrand factor, The FASEB Journal, vol.17, issue.11, pp.1490-1492, 2003. ,
DOI : 10.1096/fj.02-0830fje
Signaling Role for Phospholipase C??2 in Platelet Glycoprotein Ib?? Calcium Flux and Cytoskeletal Reorganization, Journal of Biological Chemistry, vol.90, issue.35, pp.32880-91, 2003. ,
DOI : 10.1084/jem.20020143
Analysis of the Involvement of the von Willebrand Factor?Glycoprotein Ib Interaction in Platelet Adhesion to a Collagen-Coated Surface Under Flow Conditions, Blood. 1 déc, vol.90, issue.11, pp.4413-4437, 1997. ,
Platelet-collagen interaction: is GPVI the central receptor? Blood. 15 juill, pp.449-61, 2003. ,
DOI : 10.1182/blood-2002-12-3882
GPVI and integrin alphaIIbbeta3 signaling in platelets, Journal of Thrombosis and Haemostasis, vol.272, issue.8, pp.1752-62, 2005. ,
DOI : 10.1042/BJ20031430
The future of glycoprotein??VI as an antithrombotic target, Journal of Thrombosis and Haemostasis, vol.377, issue.Suppl. 1, pp.2418-2445, 2012. ,
DOI : 10.1111/jth.12009
Platelet glycoprotein VI binds to polymerized fibrin and promotes thrombin generation, Blood, vol.126, issue.5, pp.683-91, 2015. ,
DOI : 10.1182/blood-2015-02-629717
URL : http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1000.3214
Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics, Nature, vol.83, issue.7013, pp.59-67, 2004. ,
DOI : 10.1074/jbc.271.36.21978
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372090
Structural Basis of Integrin Regulation and Signaling, Annual Review of Immunology, vol.25, issue.1, p.619, 2007. ,
DOI : 10.1146/annurev.immunol.25.022106.141618
Cell Adhesion Mechanisms in Platelets, Arteriosclerosis, Thrombosis, and Vascular Biology, vol.28, issue.3, pp.403-415, 2008. ,
DOI : 10.1161/ATVBAHA.107.150474
GPVI and ??2??1 play independent critical roles during platelet adhesion and aggregate formation to collagen under flow, Blood, vol.106, issue.4, pp.1268-77, 2005. ,
DOI : 10.1182/blood-2004-11-4434
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1895202
Involvement of activated integrin alpha2beta1 in the firm adhesion of platelets onto a surface of immobilized collagen under flow conditions, Thromb Haemost. mai, vol.83, issue.5, pp.769-76, 2000. ,
mediates outside-in regulation of platelet spreading on collagen through activation of Src kinases and PLC??2, The Journal of Cell Biology, vol.89, issue.2, pp.769-80, 2003. ,
DOI : 10.1074/jbc.M207657200
Analysis of GPIIb/IIIa receptor number by quantification of 7E3 binding to human platelets, Blood. 1 août, vol.88, issue.3, pp.907-921, 1996. ,
Initiation of Platelet Adhesion by Arrest onto Fibrinogen or Translocation on von Willebrand Factor, Cell, vol.84, issue.2, pp.289-97, 1996. ,
DOI : 10.1016/S0092-8674(00)80983-6
The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints, Molecular Pharmacology, vol.63, issue.6, pp.1256-72, 2003. ,
DOI : 10.1124/mol.63.6.1256
The G protein-coupled receptor repertoires of human and mouse, Proceedings of the National Academy of Sciences, vol.78, issue.1, pp.4903-4911, 2003. ,
DOI : 10.1038/35007072
Thrombin signalling and protease-activated receptors, Nature, vol.407, issue.6801, pp.258-64, 2000. ,
DOI : 10.1038/35025229
Protease-activated receptors in hemostasis, thrombosis and vascular biology, Journal of Thrombosis and Haemostasis, vol.77, issue.3, pp.1800-1814, 2005. ,
DOI : 10.1074/jbc.271.25.14910
G-Protein-Coupled Receptors as Signaling Targets for Antiplatelet Therapy, Arteriosclerosis, Thrombosis, and Vascular Biology, vol.29, issue.4, pp.449-57, 2009. ,
DOI : 10.1161/ATVBAHA.108.176388
Platelet thrombin receptor antagonism and atherothrombosis, European Heart Journal, vol.31, issue.1, p.17, 2010. ,
DOI : 10.1093/eurheartj/ehp504
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2800923
Evidence for Two Distinct G-protein-coupled ADP Receptors Mediating Platelet Activation, Thromb Haemost, vol.81, issue.1, pp.111-118, 1999. ,
The effect of red blood cells on the ADP-induced aggregation of human platelets in flow through tubes, Thromb Haemost. 19 févr, vol.63, issue.1, pp.112-133, 1990. ,
P2 receptors and platelet function, Purinergic Signalling, vol.323, issue.5915, pp.293-303, 2011. ,
DOI : 10.1007/s11302-011-9247-6
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166986
Phosphopleckstrin Inhibits G????-activable Platelet Phosphatidylinositol-4,5-bisphosphate 3-Kinase, Journal of Biological Chemistry, vol.271, issue.41, pp.25192-25199, 1996. ,
DOI : 10.1074/jbc.271.41.25192
Regulation and roles of PI3K??, a major actor in platelet signaling and functions, Advances in Enzyme Regulation, vol.51, issue.1, pp.106-122, 2011. ,
DOI : 10.1016/j.advenzreg.2010.09.011
The P2Y1 receptor is necessary for adenosine 5'-diphosphate-induced platelet aggregation, Blood. 1 juill, vol.92, issue.1, pp.152-161, 1998. ,
The P2X1 receptor and platelet function, Purinergic Signalling, vol.28, issue.Suppl 1, pp.341-56, 2011. ,
DOI : 10.1007/s11302-011-9224-0
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166991
Etude des mécanismes d'adhérence et d'activation des plaquettes sanguines appliquée à l'identification de nouvelles cibles anti-thrombotiques plus sûres, 2012. ,
Platelet function and Isoprostane biology. Should Isoprostanes be the newest member of the Orphan-ligand family?, Journal of Biomedical Science, vol.17, issue.1, p.24, 2010. ,
DOI : 10.1186/1423-0127-17-24
Prostanoid and TP-receptors in atherothrombosis: is there a role for their antagonism? Thromb Haemost, nov, vol.104, issue.5, pp.949-54, 2010. ,
Regulation and roles of PI3K??, a major actor in platelet signaling and functions, Advances in Enzyme Regulation, vol.51, issue.1, pp.106-122, 2011. ,
DOI : 10.1016/j.advenzreg.2010.09.011
Loss of signaling through the G protein, Gz, results in abnormal platelet activation and altered responses to psychoactive drugs, Proceedings of the National Academy of Sciences, vol.870, issue.1-2, pp.9984-9993, 2000. ,
DOI : 10.1016/S0006-8993(00)02387-8
Potential Vascular and Bleeding Complications of Treatment With Selective Serotonin Reuptake Inhibitors, Psychosomatics, vol.37, issue.1, pp.12-18, 1996. ,
DOI : 10.1016/S0033-3182(96)71592-X
Physiological implications of adenosine receptor-mediated platelet aggregation, Journal of Cellular Physiology, vol.110, issue.1, pp.46-51, 2011. ,
DOI : 10.1002/jcp.22379
Prostacyclin receptor/thromboxane receptor interactions and cellular responses in human atherothrombotic disease, Current Atherosclerosis Reports, vol.64, issue.3, pp.227-262, 2009. ,
DOI : 10.1007/s11883-009-0035-5
Platelet PECAM-1 inhibits thrombus formation in vivo, Blood, vol.107, issue.2, pp.535-576, 2006. ,
DOI : 10.1182/blood-2005-04-1512
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1895610
A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia, Proceedings of the National Academy of Sciences, vol.93, issue.14, pp.13278-13283, 1998. ,
DOI : 10.1073/pnas.93.14.7346
CalDAG-GEFI integrates signaling for platelet aggregation and thrombus formation, Nature Medicine, vol.95, issue.9, pp.982-988, 2004. ,
DOI : 10.1074/jbc.M101277200
: activation mechanisms, Journal of Thrombosis and Haemostasis, vol.68, issue.7, pp.1345-52, 2007. ,
DOI : 10.1146/annurev.biophys.31.101101.140922
A directional switch of integrin signalling and a new anti-thrombotic strategy, Nature, vol.60, issue.7474, pp.131-136, 2013. ,
DOI : 10.1038/nature12613
The small GTPase Rap1b regulates the cross talk between platelet integrin ??2beta1 and integrin ??IIbbeta3, Blood, vol.107, issue.7, pp.2728-2763, 2006. ,
DOI : 10.1182/blood-2005-07-3023
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1895386
Rap1b is required for normal platelet function and hemostasis in mice, Journal of Clinical Investigation, vol.115, issue.3, pp.680-687, 2005. ,
DOI : 10.1172/JCI22973
RASA3 is a critical inhibitor of RAP1-dependent platelet activation, Journal of Clinical Investigation, vol.125, issue.4, pp.1419-1451, 2015. ,
DOI : 10.1172/JCI77993DS1
Kindlins in FERM adhesion, Blood, vol.115, issue.20, pp.4011-4018, 1920. ,
DOI : 10.1182/blood-2009-10-239269
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875095
Rapid Ca2+-mediated activation of Rap1 in human platelets, The EMBO Journal, vol.16, issue.2, p.252, 1997. ,
DOI : 10.1093/emboj/16.2.252
CalDAG-GEFI and protein kinase C represent alternative pathways leading to activation of integrin ??IIb??3 in platelets, Blood, vol.112, issue.5, pp.1696-703, 2008. ,
DOI : 10.1182/blood-2008-02-139733
Focal Adhesions: Paradigm for a Signaling Nexus, Circulation Research, vol.98, issue.5, pp.606-622, 2006. ,
DOI : 10.1161/01.RES.0000207408.31270.db
Identification of a novel integrin signaling pathway involving the kinase Syk and the guanine nucleotide exchange factor Vav1, Current Biology, vol.8, issue.24, pp.1289-99, 1998. ,
DOI : 10.1016/S0960-9822(07)00559-3
Regulation of platelet plug formation by phosphoinositide metabolism, Blood, vol.122, issue.8, pp.1358-65, 2013. ,
DOI : 10.1182/blood-2013-05-427716
Leukocyte and platelet integrin activation and adhesion, Hématologie. 1 janv, vol.1221, issue.1, p.33, 2006. ,
Pathophysiology of inherited platelet disorders. Hématologie. 1 janv 2014, pp.20-35 ,
Guidelines for the laboratory investigation of heritable disorders of platelet function, British Journal of Haematology, vol.123, issue.Suppl. 2, pp.30-44, 2011. ,
DOI : 10.1111/j.1365-2141.2011.08793.x
In-vitro assessment of platelet function, Transfusion and Apheresis Science, vol.44, issue.3, pp.305-324, 2011. ,
DOI : 10.1016/j.transci.2011.03.006
Mean platelet volume: comparison of three analysers towards standardization of platelet morphological phenotype, International Journal of Laboratory Hematology, vol.21, issue.3, pp.300-310, 2012. ,
DOI : 10.1111/j.1751-553X.2011.01396.x
Continuing developments with the automated platelet count1, International Journal of Laboratory Hematology, vol.37, issue.2, pp.77-91, 2007. ,
DOI : 10.1111/j.1751-553X.2007.00909.x
Platelet Counting by the RBC/Platelet Ratio Method, Am J Clin Pathol. 1 mars, vol.115, issue.3, pp.460-464, 2001. ,
Immature Platelet Fraction: Establishment of a Reference Interval and Diagnostic Measure for Thrombocytopenia, The Korean Journal of Laboratory Medicine, vol.30, issue.5, pp.451-460, 2010. ,
DOI : 10.3343/kjlm.2010.30.5.451
Assessment of an immature platelet fraction (IPF) in peripheral thrombocytopenia, British Journal of Haematology, vol.17, issue.1, pp.93-102, 2004. ,
DOI : 10.1016/0969-8051(93)90146-L
Assessment of an immature platelet fraction (IFP%) in the diagnosis of thrombocytopenia], Ann Biol Clin août, vol.68, issue.4, pp.415-435, 2010. ,
Response to Prasugrel and Levels of Circulating Reticulated Platelets in Patients With ST-Segment Elevation Myocardial Infarction, Journal of the American College of Cardiology, vol.63, issue.6, pp.513-520, 2014. ,
DOI : 10.1016/j.jacc.2013.07.110
Relationship between high platelet turnover and platelet function in high-risk patients with coronary artery disease on dual antiplatelet therapy, Thrombosis and Haemostasis, vol.99, issue.5, pp.930-935, 2008. ,
DOI : 10.1160/TH08-01-0002
Immature platelet fraction (IPF) determined with an automated method predicts clopidogrel hyporesponsiveness, Journal of Thrombosis and Thrombolysis, vol.181, issue.5, pp.137-179, 2012. ,
DOI : 10.1007/s11239-011-0665-7
Impact of immature platelets on platelet response to ticagrelor and prasugrel in patients with acute coronary syndrome, European Heart Journal, vol.36, issue.45, pp.3202-3212, 2015. ,
DOI : 10.1093/eurheartj/ehv326
The gray platelet syndrome. Hématologie. 1 mars 2013, pp.123-158 ,
Description of an in vitro platelet function analyzer--PFA-100, Semin Thromb Hemost, vol.21, issue.2, pp.106-118, 1995. ,
A comparison of the effects of aspirin on bleeding time measured using the Simplate??? method and closure time measured using the PFA-100???, in healthy volunteers, British Journal of Clinical Pharmacology, vol.44, issue.2, pp.151-156, 1997. ,
DOI : 10.1046/j.1365-2125.1997.00639.x
PFA-100??? System: A New Method for Assessment of Platelet Dysfunction, Seminars in Thrombosis and Hemostasis, vol.24, issue.02, pp.195-202, 1998. ,
DOI : 10.1055/s-2007-995840
Platelet function analyzer (PFA)-100R closure time in the evaluation of platelet disorders and platelet function, Journal of Thrombosis and Haemostasis, vol.132, issue.2, pp.312-321, 2006. ,
DOI : 10.1016/S0049-3848(02)00041-5
Diagnostic performance of the platelet function analyzer (PFA-100??) for the detection of disorders of primary haemostasis in patients with a bleeding history???a systematic review and meta-analysis, Platelets, vol.4, issue.2, pp.249-60, 2007. ,
DOI : 10.1111/j.1365-2141.2005.05511.x
The PFA-100?? does not predict delta-granule platelet storage pool deficiencies, Haemophilia, vol.101, issue.Suppl. 3, pp.626-635, 2012. ,
DOI : 10.1111/j.1365-2516.2011.02733.x
Aggregation of Blood Platelets by Adenosine Diphosphate and its Reversal, Nature, vol.14, issue.4832, pp.927-936, 1962. ,
DOI : 10.1016/0006-3002(61)90250-5
The adhesiveness of native platelets and its prevention, Journal of Clinical Pathology, vol.14, issue.2, pp.140-149, 1961. ,
DOI : 10.1136/jcp.14.2.140
Platelet aggregation: a tool for clinical investigation and pharmacological study, Methodology] ,
The electronic aggregometer: A novel device for assessing platelet behavior in blood, Journal of Pharmacological Methods, vol.3, issue.2, pp.135-58, 1980. ,
DOI : 10.1016/0160-5402(80)90024-8
Detection of activated platelets in whole blood using activation-dependent monoclonal antibodies and flow cytometry, Blood. juill, vol.70, issue.1, pp.307-322, 1987. ,
Application of Flow Cytometry to Platelet Disorders, Seminars in Thrombosis and Hemostasis, vol.30, issue.5, pp.501-512, 2004. ,
DOI : 10.1055/s-2004-835671
Changes in the platelet membrane glycoprotein IIb.IIIa complex during platelet activation, J Biol Chem. 15 sept, vol.260, issue.20, pp.11107-11121, 1985. ,
Measurement of platelet factor 4 and ??-thromboglobulin by an enzyme-linked immunosorbent assay, Clinica Chimica Acta, vol.175, issue.1, pp.113-117, 1988. ,
DOI : 10.1016/0009-8981(88)90042-3
The adhesion molecule P-selectin and cardiovascular disease, European Heart Journal, vol.24, issue.24, pp.2166-79, 2003. ,
DOI : 10.1016/j.ehj.2003.08.021
Platelet dense granule membranes contain both granulophysin and P-selectin (GMP-140) ,
[16] Measurement of secretion of adenine nucleotides, Methods Enzymol, vol.169, pp.195-205, 1989. ,
DOI : 10.1016/0076-6879(89)69060-X
Further evidence for a deficient storage pool of adenine nucleotides in platelets from some patients with thrombocytopathia--« storage pool disease », Blood. févr, vol.39, issue.2, pp.197-209, 1972. ,
Increase in density and accumulation of serotonin by human aging platelets, American Journal of Hematology, vol.52, issue.1, pp.11-21, 1984. ,
DOI : 10.1002/ajh.2830170103
Platelet serotonin content and free and total plasma tryptophan in healthy volunteers during 24 hours, Clin Chem, vol.39, issue.11, pp.2337-2340, 1993. ,
A modified HPLC technique for simultaneous measurement of 5-hydroxytryptamine and 5-hydroxyindoleacetic acid in cerebrospinal fluid, platelet and plasma, Life Sciences, vol.47, issue.19, pp.1751-1760, 1990. ,
DOI : 10.1016/0024-3205(90)90349-V
Comparative analysis of serotonin in equine plasma with liquid chromatography-tandem mass spectrometry and enzyme-linked immunosorbent assay, Journal of Veterinary Diagnostic Investigation, vol.24, issue.6, pp.1035-1077, 2012. ,
DOI : 10.1177/1040638712457928
Flow cytometry detection of serotonin content and release in resting and activated platelets, British Journal of Haematology, vol.98, issue.6, pp.892-898, 2003. ,
DOI : 10.1002/cyto.1170
Diagnosing Platelet ??-Storage Pool Disease in Children by Flow Cytometry, American Journal of Clinical Pathology, vol.127, issue.4, pp.626-658, 2007. ,
DOI : 10.1309/3KRYCPNAPDTVFWGY
The lumi-aggregometer: a new instrument for simultaneous measurement of secretion and aggregation by platelets, J Lab Clin Med. juill, vol.90, issue.1, pp.125-134, 1977. ,
Light Transmission Aggregometry and ATP Release for the Diagnostic Assessment of Platelet Function, Seminars in Thrombosis and Hemostasis, vol.35, issue.02, pp.158-67, 2009. ,
DOI : 10.1055/s-0029-1220324
A flow cytometric assay using mepacrine for study of uptake and release of platelet dense granule contents, British Journal of Haematology, vol.45, issue.2, pp.380-385, 1995. ,
DOI : 10.1111/j.1365-2141.1995.tb03315.x
Diagnosis of inherited platelet function disorders: guidance from the SSC of the ISTH, Journal of Thrombosis and Haemostasis, vol.10, issue.2, pp.314-336, 2015. ,
DOI : 10.1111/jth.12792
ISTH/SSC bleeding assessment tool: a standardized questionnaire and a proposal for a new bleeding score for inherited bleeding disorders, Journal of Thrombosis and Haemostasis, vol.97, issue.Suppl. 1, pp.2063-2068, 2010. ,
DOI : 10.1111/j.1538-7836.2010.03975.x
Glanzmann thrombasthenia: a review of ITGA2B and ITGB3 defects with emphasis on variants, phenotypic variability, and mouse models, Blood, vol.118, issue.23, pp.5996-6005, 2011. ,
DOI : 10.1182/blood-2011-07-365635
Bernard-Soulier syndrome (hemorrhagiparous thrombocytic dystrophy) ,
URL : https://hal.archives-ouvertes.fr/inserm-00122094
Absence of collagen-induced platelet activation caused by compound heterozygous GPVI mutations, Blood, vol.114, issue.9, pp.1900-1903, 2009. ,
DOI : 10.1182/blood-2009-03-213504
A compound heterozygous mutation in glycoprotein VI in a patient with a bleeding disorder, Journal of Thrombosis and Haemostasis, vol.299, issue.8, pp.1356-63, 2009. ,
DOI : 10.1111/j.1538-7836.2009.03520.x
Platelet type von Willebrand disease and registry report: communication from the SSC of the ISTH, Journal of Thrombosis and Haemostasis, vol.139, issue.2, pp.411-415, 2016. ,
DOI : 10.1111/jth.13204
The platelet P2Y12 receptor for adenosine diphosphate: congenital and drug-induced defects, Blood, vol.117, issue.7, pp.2102-2114, 2011. ,
DOI : 10.1182/blood-2010-08-263111
Phenotypic approaches to gene mapping in platelet function disorders -identification of new variant of P2Y12, TxA2 and GPVI receptors, Hamostaseologie. janv, vol.30, issue.1, pp.29-38, 2010. ,
Two thromboxane A2 receptor isoforms in human platelets. Opposite coupling to adenylyl cyclase with different sensitivity to Arg60 to Leu mutation., Journal of Clinical Investigation, vol.97, issue.4, pp.949-56, 1996. ,
DOI : 10.1172/JCI118518
A novel thromboxane A2 receptor D304N variant that abrogates ligand binding in a patient with a bleeding diathesis, Blood, vol.115, issue.2, pp.363-372, 2010. ,
DOI : 10.1182/blood-2009-08-236976
Thromboxane synthase mutations in an increased bone density disorder (Ghosal syndrome), Nature Genetics, vol.4, issue.3, pp.284-290, 2008. ,
DOI : 10.1016/S0163-7827(00)00016-3
) mutation affects platelet function and causes severe bleeding, The Journal of Experimental Medicine, vol.96, issue.7, pp.1349-62, 2014. ,
DOI : 10.1074/jbc.M111.239608
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076591
Novel mutations in RASGRP2 encoding for CalDAG-GEFI abrogate Rap1 activation causing platelet dysfunction, Blood. 1 janv, pp.2015-2026, 2016. ,
DOI : 10.1182/blood-2015-11-683102
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009515
Human CalDAG-GEFI deficiency increases bleeding and delays ??IIb??3 activation, Blood, vol.128, issue.23, pp.2729-2762, 2016. ,
DOI : 10.1182/blood-2016-03-704825
Leukocyte Adhesion Deficiency III - When Integrins Activation Fails, Journal of Clinical Immunology, vol.103, issue.1, pp.900-903, 2014. ,
DOI : 10.1007/s10875-014-0094-4
Noonan syndrome, The Lancet, vol.381, issue.9863, p.333, 2013. ,
DOI : 10.1016/S0140-6736(12)61023-X
URL : https://hal.archives-ouvertes.fr/hal-00562941
Spectrum of Mutations in Noonan Syndrome and Their Correlation with Phenotypes, The Journal of Pediatrics, vol.159, issue.6, pp.1029-1064, 2011. ,
DOI : 10.1016/j.jpeds.2011.05.024
Medical complications, clinical findings, and educational outcomes in adults with Noonan syndrome, American Journal of Medical Genetics Part A, vol.136, issue.12, pp.3106-3117, 2012. ,
DOI : 10.1002/ajmg.a.35639
Hemostatic Abnormalities in Noonan Syndrome, PEDIATRICS, vol.133, issue.5, pp.1299-304, 2014. ,
DOI : 10.1542/peds.2013-3251
Le syndrome des plaquettes grises. Hématologie. 1 mars 2013, pp.123-158 ,
Quebec Platelet Disorder: Update on Pathogenesis, Diagnosis, and Treatment, Seminars in Thrombosis and Hemostasis, vol.37, issue.06, 2011. ,
DOI : 10.1055/s-0031-1291382
Mutations in VPS33B, encoding a regulator of SNARE-dependent membrane fusion, cause arthrogryposis???renal dysfunction???cholestasis (ARC) syndrome, Nature Genetics, vol.36, issue.4, pp.400-404, 2004. ,
DOI : 10.1038/ng1325
Requirement of VPS33B, a member of the Sec1/Munc18 protein family, in megakaryocyte and platelet ??-granule biogenesis, Blood, vol.106, issue.13, pp.4159-66, 2005. ,
DOI : 10.1182/blood-2005-04-1356
Paris-Trousseau syndrome : clinical, hematological, molecular data of ten new cases, Thrombosis and Haemostasis, vol.90, issue.5, pp.893-900, 2003. ,
DOI : 10.1160/TH03-02-0120
Role of MRP4 (ABCC4) in Platelet Adenine Nucleotide-Storage, The American Journal of Pathology, vol.176, issue.3, pp.1097-103, 2010. ,
DOI : 10.2353/ajpath.2010.090425
Clinical, Molecular, and Cell Biological Aspects of Chediak???Higashi Syndrome, Molecular Genetics and Metabolism, vol.68, issue.2, pp.283-303, 1999. ,
DOI : 10.1006/mgme.1999.2927
Protein truncation test of LYST reveals heterogenous mutations in patients with Chediak- Higashi syndrome, Blood. 1 févr, vol.95, issue.3, pp.979-83, 2000. ,
Disorders of Lysosome-Related Organelle Biogenesis: Clinical and Molecular Genetics, Annual Review of Genomics and Human Genetics, vol.9, issue.1, pp.359-86, 2008. ,
DOI : 10.1146/annurev.genom.9.081307.164303
Isolated deficiency of platelet procoagulant activity, The American Journal of Medicine, vol.67, issue.2, pp.206-219, 1979. ,
DOI : 10.1016/0002-9343(79)90392-9
Calcium-dependent phospholipid scrambling by TMEM16F, Nature, vol.13, issue.7325, pp.834-842, 2010. ,
DOI : 10.1038/nature09583
Ca2+-dependent phospholipid scrambling by a reconstituted TMEM16 ion channel, Nature Communications, vol.35, p.2367, 2013. ,
DOI : 10.1038/ncomms3367
URL : http://doi.org/10.1038/ncomms3367
Differential membrane binding and diacylglycerol recognition by C1 domains of RasGRPs, Biochemical Journal, vol.406, issue.2, p.223, 2007. ,
DOI : 10.1042/BJ20070294
Differential membrane binding and diacylglycerol recognition by C1 domains of RasGRPs, Biochemical Journal, vol.406, issue.2, pp.223-259, 2007. ,
DOI : 10.1042/BJ20070294
Characterization of RasGRP2, a Plasma Membrane-targeted, Dual Specificity Ras/Rap Exchange Factor, Journal of Biological Chemistry, vol.275, issue.41, pp.32260-32267, 2000. ,
DOI : 10.1074/jbc.M006087200
Structural Basis for the Failure of the C1 Domain of Ras Guanine Nucleotide Releasing Protein 2 (RasGRP2) to Bind Phorbol Ester with High Affinity, Journal of Biological Chemistry, vol.291, issue.21, pp.11133-11180, 2016. ,
DOI : 10.1074/jbc.M116.725333
The kinetics of ??IIb??3 activation determines the size and stability of thrombi in mice: implications for antiplatelet therapy, Blood, vol.117, issue.3, pp.1005-1018, 2011. ,
DOI : 10.1182/blood-2010-07-297713
Fractionation of Subcellular Organelles, In: Curr Protoc Cell Biol Inc, vol.195, 2015. ,
DOI : 10.1002/0471143030.cb0301s69
Novel mutations in RASGRP2 encoding for CalDAG-GEFI abrogate Rap1 activation causing platelet dysfunction, Blood. 1 janv, pp.2015-2026, 2016. ,
DOI : 10.1182/blood-2015-11-683102
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009515
Rap1-Rac1 Circuits Potentiate Platelet Activation, Arteriosclerosis, Thrombosis, and Vascular Biology, vol.32, issue.2, pp.434-475, 2012. ,
DOI : 10.1161/ATVBAHA.111.239194
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262085
The Par polarity complex regulates Rap1- and chemokine-induced T cell polarization, The Journal of Cell Biology, vol.176, issue.6, pp.863-75, 2007. ,
DOI : 10.1038/ncb1368
Rap1 promotes cell spreading by localizing Rac guanine nucleotide exchange factors, The Journal of Cell Biology, vol.81, issue.1, pp.111-133, 2004. ,
DOI : 10.1006/excr.1999.4695
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172522
F-actin-dependent Translocation of the Rap1 GDP/GTP Exchange Factor RasGRP2, Journal of Biological Chemistry, vol.279, issue.19, pp.20435-20481, 2004. ,
DOI : 10.1074/jbc.M313013200
A Selective Role for Phosphatidylinositol 3,4,5-Trisphosphate in the Gi-dependent Activation of Platelet Rap1B, Journal of Biological Chemistry, vol.278, issue.1, pp.131-139, 2003. ,
DOI : 10.1074/jbc.M204821200
C1 domains exposed: From diacylglycerol binding to protein???protein interactions, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, vol.1761, issue.8, pp.827-864, 2006. ,
DOI : 10.1016/j.bbalip.2006.05.001
Protein Kinase C ?? Is Negatively Regulated by 14-3-3 Signal Transduction Proteins, Journal of Biological Chemistry, vol.274, issue.14, pp.9258-64, 1999. ,
DOI : 10.1074/jbc.274.14.9258
Elucidation of Binding Determinants and Functional Consequences of Ras/Raf-Cysteine-rich Domain Interactions, Journal of Biological Chemistry, vol.275, issue.29, pp.22172-22181, 2000. ,
DOI : 10.1074/jbc.M000397200
Mice lacking the signaling molecule CalDAG-GEFI represent a model for leukocyte adhesion deficiency type III, Journal of Clinical Investigation, vol.117, issue.6, pp.1699-707, 2007. ,
DOI : 10.1172/JCI30575
Calcium-Diacylglycerol Guanine Nucleotide Exchange Factor I gene mutations associated with loss of function in canine platelets, Translational Research, vol.150, issue.2, pp.81-92, 2007. ,
DOI : 10.1016/j.trsl.2007.03.006
Mice Expressing Low Levels of CalDAG-GEFI Exhibit Markedly Impaired Platelet Activation With Minor Impact on HemostasisHighlights, Arteriosclerosis, Thrombosis, and Vascular Biology, vol.36, issue.9, pp.1838-1884, 2016. ,
DOI : 10.1161/ATVBAHA.116.307874