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Master Thesis

Réévaluation de l’antibiothérapie dans l’infection urinaire : est-elle applicable en médecine générale ?

Abstract : Introduction. Bacterial resistance is a major public health problem. Urinary tract infections represent 20% of general practitioners’s antibiotic prescriptions. This antibotic-therapy should be reassessed and confirmed after 3 days (except for short treatments). As far as we know, there is few data about this revaluation for outpatients.This study aims to assess revaluation rate for urinary tract infections treated in ambulatory.Material and method : We present a bicentric prospective study including all consecutive patients coming for urinalyses in one of the laboratory associated to this study. At D3/D4, a phone call to patients and to generalist doctors allows to measure the revaluation rate of empirical antibiotic therapies. Secondary objectives of the study are to assess the numbers of urinalyses prescribed without recommandations and to estimate compliance with national guidelines for empirical and documented antibiotic treatments. Results. Fourty-six patients were included. Four patients did not answer to phone call. On these 42 patients, 33 received a treatment of more than 3 days. Among theses, 22 benefited from revaluation at D3 (66,7%). Twenty four urinalyses were prescribed without recommandations for uncomplicated cystitis. General practitioners were compliant with recommdantions for 53,6% concerning empirical antibiotic treatments. Only, 45,4% of antibiotic treatments were adapted after reassesment. Conclusion. This study shows a correct reassesment rate of empirical antibiotic therapies given in outpatients with urinary tract infections. It assesses compliance with recommandations for a large pannel of general practitioners. Low conformity rate after microbiological documentation confirms the need to implant stewardship programs in general medicine.
Document type :
Master Thesis
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Contributor : Jean-Hugues Morneau <>
Submitted on : Thursday, June 1, 2017 - 4:20:48 PM
Last modification on : Wednesday, July 15, 2020 - 8:58:04 AM
Long-term archiving on: : Wednesday, December 13, 2017 - 3:05:35 AM


  • HAL Id : dumas-01531467, version 1


Raphaël Bonnet, Emmanuelle Pasquet. Réévaluation de l’antibiothérapie dans l’infection urinaire : est-elle applicable en médecine générale ?. Médecine humaine et pathologie. 2017. ⟨dumas-01531467⟩



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