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Master Thesis

Defining reference interval of haemoglobin in early postpartum: the actual cut-off for postpartum anaemia

Abstract : Introduction: Postpartum anaemia is defined as haemoglobin below 100 g/L by an international agreement. It has never been determined scientifically yet. The main purpose of this study was to assess the reference interval for haemoglobin in puerperal women and so define a cut-off value for postpartum anaemia. Methods: This retrospective study was performed in the University Hospital of Grenoble, between March 2013 and December 2015. Haemoglobin values two days after delivery were collected. Healthy women were included, aged between 18 and 43 years old, with a single, normal pregnancy, follow up and delivery. Haemoglobin reference interval was set between the 2.5th and the 97.5th percentile. Cut-off for anaemia was set at the 2.5th percentile. Haemoglobin was also statistically compared to other blood and clinical factors. Results: 1723 haemoglobin values ranged from 60 g/L to 154 g/L. Mean was 112 g/L. Standard deviation was 13 g/L. Cut-off value for anaemia was 85 g/L. Hb<85g/L was significantly correlated with low age (OR=0.87[0.82; 0.93]), and blood loss>300mL (p<0.001). Conclusion: This study determined haemoglobin standard and cut-off for anaemia on the second day after eutocic delivery. Subsequent studies should be conducted to determine whether the threshold is consistent with clinical outcomes of anaemia in order to determine a suitable iron supplementation program.
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Master Thesis
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Submitted on : Thursday, September 7, 2017 - 4:21:36 PM
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  • HAL Id : dumas-01583624, version 1


Clara Spitalier, Marion Benbournane. Defining reference interval of haemoglobin in early postpartum: the actual cut-off for postpartum anaemia. Human health and pathology. 2017. ⟨dumas-01583624⟩



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