R. Wills, W. Crouthamel, F. Iber, and M. Perkal, Influence of Alcohol on the Pharmacokinetics of Diazepam Controlled-Release Formulation in Healthy Volunteers, The Journal of Clinical Pharmacology, vol.143, issue.11, pp.557-561, 1982.
DOI : 10.1016/S0378-4347(00)81313-4

. Le, une composante santé qui évolue avec l'âge, Innovations Agronomiques, vol.33, issue.1, pp.37-46, 2013.

. Absorption-des-médicaments-jennifer-le, M. Pharmd, and . Bcps-id, Skaggs School of Pharmacy and Pharmaceutical Sciences Disponible sur http

C. Ayme-dietrich, Verstuyft edimark.fr [15] Impact of P-glycoprotein-mediated intestinal efflux kinetics on oral bioavailability of Pglycoprotein substrates Mol Pharm, pp.455-65, 2004.

L. Doyle, W. Yang, and L. Abruzzo, A multidrug resistance transporter from human MCF-7 breast cancer cells, Proceedings of the National Academy of Sciences, vol.5, issue.10, pp.15665-70, 1998.
DOI : 10.1093/hmg/5.10.1649

URL : http://www.pnas.org/content/95/26/15665.full.pdf

H. Törnblom and G. Lindberg, Correlation of gene expression of ten drug efflux proteins of the ATP-binding cassette transporter family in normal human jejunum and in human intestinal epithelial Caco-2 cell monolayers, J Taipalensuu J Pharmacol Exp Ther, vol.299, pp.164-70, 2001.

S. Grad and L. Abenavoli, The Effect of Alcohol on Gastrointestinal Motility, Reviews on Recent Clinical Trials, vol.11, issue.3, pp.191-196, 2016.
DOI : 10.2174/1574887111666160815103251

H. M. Mcconnell and A. W. Fadda, Basit Article ~ 86 Food-induced "dose-dumping" from a once-a-day theophylline product as a cause of theophylline toxicity, International Journal of Pharmaceutics, vol.3642987, issue.26, pp.758-65, 1985.

. Fiche-pratique-pharmacocinétique-de-l-'omedit and . Poitou, Charentes Disponible sur https://omedit.esante-poitou-charentes.fr/portail/gallery_files/site

. Médicaments, Disponible sur le site : https://omedit.esante-poitou-charentes.fr/portail/gallery_files/site

B. Kirby and J. Unadkat, Grapefruit Juice, a Glass Full of Drug Interactions?, Clinical Pharmacology & Therapeutics, vol.70, issue.5, pp.631-633, 1038.
DOI : 10.1038/sj.clpt.6100185

. Abus, usage récréatifs, addiction dopage, les cahiers de l'Ordre national des pharmaciens, 2015.

O. Centre, Broyage Modules en e-learning de L'Omédit e-learning

M. K. Romach, K. A. Schoedel, and E. M. Sellers, Update on tamper-resistant drug formulations, Drug and Alcohol Dependence, vol.130, issue.1-3, pp.13-23, 2013.
DOI : 10.1016/j.drugalcdep.2012.12.028

. Disponible-en-ligne-sur, sante.fr/var/ansm_site/storage/original/application/220170fe1e36e383f0d0ce3c0c 4c80a8.pdf [54] La prise concomitante d'alcool avec des substances psychoactives quels produits par quels consommateurs ? Christophe Moracchini

X. Amaslidou and . Thirion, Joëlle Micallef 7eme atelier d'addictovigilance de Biarritz, p.24

. Disponible-sur-https, org/forum/t11824-p1-Purple-drank-deja-teste.html [57] Regulatory Considerations for Alcohol-Induced Dose Dumping of Oral Modified-Release Formulations " Thomas P. Friebe, Firouz Asgarzadeh, 2015.

. S. Henderson, Ethanol Does Not Alter the Pharmacokinetic Profile of the Controlled-release Formulation of Carvedilol, The Journal of Clinical Pharmacology, vol.5, issue.suppl, pp.1358-1365, 2007.
DOI : 10.1007/BF01065396

E. /. Cpmp and . Ewp, 96 Corr1 Draft XXIII [63] Oral Controlled Release Formulation Design and Drug Delivery: Theory to Practice publié par Hong Wen

M. Evans, G. Broe, E. Triggs, M. Cheung, H. Creasey et al., Gastric emptying rate and the systemic availability of levodopa in the elderly parkinsonian patient, Neurology, vol.31, issue.10, pp.1288-94, 1981.
DOI : 10.1212/WNL.31.10.1288

. Kétoprofene, Omeprazole Ethypharm® 200mg, gélule à libération modifiée, Afssaps ? Septembre, 2011.

. Siepmann, 1250-1258] + [Ethanol-resistant polymeric film coatings for controlled drug delivery, European Journal of Pharmaceutics and Biopharmaceutics, vol.85, 2013.

W. Evonik, Strategies for alcohol resistant modified release formulations, F

A. Resistance, S. Guha, V. Joshi, and K. Jain, Gadilkar Evonik Industries [81] A new extended released formulation (OROS ® ) of hydromorphone in the management of pain, Weinstein S.M., Ther.Clin. Risk Manag, vol.5, pp.75-80, 2009.

M. K. Romach, K. A. Schoedel, and E. M. Sellers, Update on tamper-resistant drug formulations, Drug and Alcohol Dependence, vol.130, issue.1-3, pp.13-23, 2013.
DOI : 10.1016/j.drugalcdep.2012.12.028

C. Ewp, 1 Corr. 2** Page 41/59 Appendix II [86] Sink Condition: Solely an in vitro (analytical chemistry) and not the in vivo or physiological requirement, 2012.

. Codéine, deux décès depuis janvier, Le figaro article du 9, 2017.

D. Codéine, éthylmorphine et noscapine : prescription médicale obligatoire, liste des produits conçus Jean Philippe Rivière, 2017.