Qualité de vie, mortalité et facteurs associés, six mois après une hospitalisation en réanimation : étude observationnelle

Abstract : Background: advances in critical care medicine have improved patients’ survival rate. However, physical and cognitive sequels as well as mortality rate after Intensive Care Unit (ICU) discharge remain substantial. Our objectives were to evaluate the Quality of Life (QOL) and the mortality rate after ICU discharge, and identify the risk factors of these outcomes. Methods: we performed a single-center prospective observational study. The Short Form 36 (SF-36) was used to evaluate the QOL on preadmission, at 3- and 6-month after ICU discharge. The mortality rate was also assessed at 3- and 6-month after ICU discharge. Results: two hundred twenty patients were included. During the follow-up period significant improvement were recorded in the bodily pain scale, general health perceptions and emotional role functioning compared to the preadmission status in ICU. Factors independently associated with the 6-month QOL were age, preadmission QOL score, SAPS II, prolonged mechanical ventilation (> 3 days) and the occurrence of acute respiratory distress syndrome. The 6-month mortality rate was 19.2 % (IC 95% [13.7-24.7]) and its risk factors were age, medical reason of ICU admission and prolonged mechanical ventilation (> 3days). Conclusion: three scaled score of the SF-36 improved among the survivors admitted in ICU at 3- and 6-month after discharge. A better knowledge of the risk factors leading to QOL impairment and increased 6-month mortality rate may lead to an early detection of high-risk patients and might help guiding specific patients’ care and organizational strategies.
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Master Thesis
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Nathan Ferrand. Qualité de vie, mortalité et facteurs associés, six mois après une hospitalisation en réanimation : étude observationnelle. Médecine humaine et pathologie. 2017. ⟨dumas-01611684⟩

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